PDB: 184427 件ウェブページステータス検索Chemie searchBIRD

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5MC9	Crystal structure of the heterotrimeric integrin-binding region of laminin-111 分子名称: CALCIUM ION, Laminin subunit alpha-1, Laminin subunit beta-1, ... 著者 Pulido, D, Hohenester, E. 登録日 2016-11-09 公開日 2017-02-08 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Crystal Structure of the Heterotrimeric Integrin-Binding Region of Laminin-111. Structure, 25, 2017
5FXS	IGFR-1R complex with a pyrimidine inhibitor. 分子名称: 2-[4-[4-[[(6Z)-5-chloranyl-6-pyrazolo[1,5-a]pyridin-3-ylidene-1H-pyrimidin-2-yl]amino]-3,5-dimethyl-pyrazol-1-yl]piperidin-1-yl]-N,N-dimethyl-ethanamide, ACETATE ION, INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR 著者 Degorce, S, Boyd, S, Curwen, J, Ducray, R, Halsall, C, Jones, C, Lach, F, Lenz, E, Pass, M, Pass, S, Trigwell, C, Norman, R, Phillips, C. 登録日 2016-03-02 公開日 2016-10-19 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Discovery of a Potent, Selective, Orally Bioavailable, and Efficacious Novel 2-(Pyrazol-4-ylamino)-pyrimidine Inhibitor of the Insulin-like Growth Factor-1 Receptor (IGF-1R). J. Med. Chem., 59, 2016
4GQK	Structure of Native VgrG1-ACD with ADP (no cations) 分子名称: ADENOSINE-5'-DIPHOSPHATE, SULFATE ION, VgrG protein 著者 Nguyen, V.S, Spinelli, S, Derrez, E, Durand, E, Cambillau, C. 登録日 2012-08-23 公開日 2013-09-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Structure of Native VgrG1-ACD with ADP (no cations) To be Published
5LFB	Structure of the bacterial sex F pilus (12.5 Angstrom rise) 分子名称: Pilin, [(2~{S})-3-[[(2~{R})-2,3-bis(oxidanyl)propoxy]-oxidanyl-phosphoryl]oxy-2-hexadec-9-enoyloxy-propyl] hexadecanoate 著者 Costa, T.R.D, Ilangovan, I, Ukleja, M, Redzej, A, Santini, J.M, Smith, T.K, Egelman, E.H, Waksman, G. 登録日 2016-06-30 公開日 2016-11-02 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (5 Å) 主引用文献 Structure of the Bacterial Sex F Pilus Reveals an Assembly of a Stoichiometric Protein-Phospholipid Complex. Cell, 166, 2016
4GR0	Crystal structure of the catalytic domain of Human MMP12 in complex with selective phosphinic inhibitor RXP470B 分子名称: CALCIUM ION, Macrophage metalloelastase, N-[(2S)-3-[(R)-(4-bromophenyl)(hydroxy)phosphoryl]-2-{[3-(3'-chlorobiphenyl-4-yl)-1,2-oxazol-5-yl]methyl}propanoyl]-L-a lanyl-L-alaninamide, ... 著者 Stura, E.A, Vera, L, Beau, F, Devel, L, Cassar-Lajeunesse, E, Dive, V. 登録日 2012-08-24 公開日 2013-02-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.497 Å) 主引用文献 Molecular determinants of a selective matrix metalloprotease-12 inhibitor: insights from crystallography and thermodynamic studies. J.Med.Chem., 56, 2013
3P70	Structural basis of thrombin-mediated factor V activation: essential role of the hirudin-like sequence Glu666-Glu672 for processing at the heavy chain-B domain junction 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BENZAMIDINE, ... 著者 Corral-Rodriguez, M.A, Bock, P.E, Hernandez-Carvajal, E, Gutierrez-Gallego, R, Fuentes-Prior, P. 登録日 2010-10-11 公開日 2011-09-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural basis of thrombin-mediated factor V activation: the Glu666-Glu672 sequence is critical for processing at the heavy chain-B domain junction. Blood, 117, 2011
3BB1	Crystal structure of Toc34 from Pisum sativum in complex with Mg2+ and GMPPNP 分子名称: GLYCEROL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... 著者 Koenig, P, Sinning, I, Schleiff, E, Tews, I. 登録日 2007-11-09 公開日 2008-04-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 The GTPase cycle of the chloroplast import receptors Toc33/Toc34: implications from monomeric and dimeric structures. Structure, 16, 2008
4DOO	Crystal structure of Arabidopsis thaliana fatty-acid binding protein At3g63170 (AtFAP1) 分子名称: Chalcone-flavanone isomerase family protein, LAURIC ACID, POTASSIUM ION 著者 Noel, J.P, Pojer, F, Louie, G.V, Bowman, M.E. 登録日 2012-02-09 公開日 2012-05-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Evolution of the chalcone-isomerase fold from fatty-acid binding to stereospecific catalysis. Nature, 485, 2012
3DWI	Crystal structure of Mycobacterium tuberculosis CysM, the cysteine synthase B 分子名称: Cysteine synthase B, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION 著者 Jurgenson, C.T, Burns, K.E, Begley, T.P, Ealick, S.E. 登録日 2008-07-22 公開日 2008-09-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 Crystal structure of a sulfur carrier protein complex found in the cysteine biosynthetic pathway of Mycobacterium tuberculosis. Biochemistry, 47, 2008
5G21	Leishmania major N-myristoyltransferase in complex with a quinoline inhibitor (compound 26). 分子名称: ETHYL 4-[(2-CYANOETHYL)SULFANYL]-6-{[6-(PIPERAZIN-1-YL), GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, MAGNESIUM ION, ... 著者 Goncalves, V, Brannigan, J.A, Laporte, A, Bell, A.S, Roberts, S.M, Wilkinson, A.J, Leatherbarrow, R.J, Tate, E.W. 登録日 2016-04-06 公開日 2017-02-15 最終更新日 2017-06-28 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure-guided optimization of quinoline inhibitors of Plasmodium N-myristoyltransferase. Medchemcomm, 8, 2017
5G2U	Structure of BT1596,a 2-O GAG sulfatase 分子名称: 2-O GLYCOSAMINOGLYCAN SULFATASE, CITRIC ACID, ZINC ION 著者 Cartmell, A, Lowe, E.C, Basle, A, Crouch, L.I, Czjzek, M, Turnbull, J, Henrissat, B, Terrapon, N, Thomas, S, Murray, H, Firbank, S.J, Bolam, D.N. 登録日 2016-04-14 公開日 2017-05-24 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 How members of the human gut microbiota overcome the sulfation problem posed by glycosaminoglycans. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1Y1Q	Crystal Structure of the Uridine Phosphorylase from Salmonella Typhimurium in Complex with Uridine-5p-monophosphate and Sulfate Ion at 2.35A Resolution 分子名称: SULFATE ION, URIDINE-5'-MONOPHOSPHATE, Uridine phosphorylase 著者 Gabdoulkhakov, A.G, Dontsova, M.V, Kachalova, G.S, Betzel, C, Ealick, S.E, Mikhailov, A.M. 登録日 2004-11-19 公開日 2005-11-22 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Crystal Structures of Salmonella Typhimurium Uridine Phosphorylase in Native and Three Complexes Forms - with Uridine, Uracil and Sulfate. To be Published
5JUV	STRUCTURE OF E298Q-BETA-GALACTOSIDASE FROM ASPERGILLUS NIGER IN COMPLEX WITH 6-b-Galactopyranosyl galactose 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, PENTAETHYLENE GLYCOL, ... 著者 Rico-Diaz, A, Ramirez-Escudero, M, Vizoso Vazquez, A, Cerdan, M.E, Becerra, M, Sanz-Aparicio, J. 登録日 2016-05-10 公開日 2017-04-19 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Structural features of Aspergillus niger beta-galactosidase define its activity against glycoside linkages. FEBS J., 284, 2017
7E3Z	Non-Ribosomal Peptide Synthetases, Thioesterase 分子名称: CHLORIDE ION, thioesterase 著者 Jung, Y.E, Cha, S.S. 登録日 2021-02-09 公開日 2021-12-22 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Unprecedented Noncanonical Features of the Nonlinear Nonribosomal Peptide Synthetase Assembly Line for WS9326A Biosynthesis. Angew.Chem.Int.Ed.Engl., 60, 2021
1Y9H	Methylation of cytosine at C5 in a CpG sequence context causes a conformational switch of a benzo[a]pyrene diol epoxide-N2-guanine adduct in DNA from a minor groove alignment to intercalation with base displacement 分子名称: 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE, 5'-D(*CP*CP*AP*TP*(5CM)P*(BPG)P*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*CP*GP*AP*TP*GP*G)-3' 著者 Zhang, N, Lin, C, Huang, X, Kolbanovskiy, A, Hingerty, B.E, Amin, S, Broyde, S, Geacintov, N.E, Patel, D.J. 登録日 2004-12-15 公開日 2005-03-22 最終更新日 2024-04-24 実験手法 SOLUTION NMR 主引用文献 Methylation of cytosine at C5 in a CpG sequence context causes a conformational switch of a benzo[a]pyrene diol epoxide-N2-guanine adduct in DNA from a minor groove alignment to intercalation with base displacement. J.Mol.Biol., 346, 2005
7E9Y	Crystal structure of eLACCO1 分子名称: (2S)-2-HYDROXYPROPANOIC ACID, CALCIUM ION, Lactate-binding periplasmic protein TTHA0766,Lactate-binding periplasmic protein TTHA0766 著者 Wen, Y, Campbell, R.E, Lemieux, M.J, Nasu, Y. 登録日 2021-03-05 公開日 2021-12-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 A genetically encoded fluorescent biosensor for extracellular L-lactate. Nat Commun, 12, 2021
2OMU	Crystal structure of InlA G194S+S Y369S/hEC1 complex 分子名称: CALCIUM ION, CHLORIDE ION, Epithelial-cadherin, ... 著者 Wollert, T, Heinz, D.W, Schubert, W.D. 登録日 2007-01-23 公開日 2007-08-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Thermodynamically reengineering the listerial invasion complex InlA/E-cadherin. Proc.Natl.Acad.Sci.Usa, 104, 2007
3J6U	Cryo-EM structure of Dengue virus serotype 3 in complex with human antibody 5J7 Fab 分子名称: Fab 5J7 heavy chain, Fab 5J7 light chain, envelope protein, ... 著者 Fibriansah, G, Tan, J.L, Smith, S.A, de Alwis, R, Ng, T.-S, Kostyuchenko, V.A, Kukkaro, P, de Silva, A.M, Crowe Jr, J.E, Lok, S.-M. 登録日 2014-03-26 公開日 2015-03-04 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (9 Å) 主引用文献 A highly potent human antibody neutralizes dengue virus serotype 3 by binding across three surface proteins. Nat Commun, 6, 2015
2ANY	Expression, Crystallization and the Three-dimensional Structure of the Catalytic Domain of Human Plasma Kallikrein: Implications for Structure-Based Design of Protease Inhibitors 分子名称: BENZAMIDINE, PHOSPHATE ION, plasma kallikrein, ... 著者 Tang, J, Yu, C.L, Williams, S.R, Springman, E, Jeffery, D, Sprengeler, P.A, Estevez, A, Sampang, J, Shrader, W, Spencer, J.R, Young, W.B, McGrath, M.E, Katz, B.A. 登録日 2005-08-11 公開日 2005-10-11 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Expression, crystallization, and three-dimensional structure of the catalytic domain of human plasma kallikrein. J.Biol.Chem., 280, 2005
5LSB	Crystal structure of yeast Hsh49p in complex with Cus1p binding domain. 分子名称: Cold sensitive U2 snRNA suppressor 1, Protein HSH49 著者 van Roon, A.M, Obayashi, E, Sposito, B, Oubridge, C, Nagai, K. 登録日 2016-08-24 公開日 2017-04-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of U2 snRNP SF3b components: Hsh49p in complex with Cus1p-binding domain. RNA, 23, 2017
5EIZ	Crystal structure of Y99A mutant of human macrophage migration inhibitory factor 分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... 著者 Pantouris, G, Lolis, E. 登録日 2015-10-30 公開日 2015-11-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Nanosecond Dynamics Regulate the MIF-Induced Activity of CD74. Angew. Chem. Int. Ed. Engl., 2018
5M28	Maltodextrin binding protein MalE1 from L. casei BL23 bound to maltotriose 分子名称: CHLORIDE ION, MalE1, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose 著者 Homburg, C, Bommer, M, Wuttge, S, Hobe, C, Beck, S, Dobbek, H, Deutscher, J, Licht, A, Schneider, E. 登録日 2016-10-12 公開日 2017-07-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.079 Å) 主引用文献 Inducer exclusion in Firmicutes: insights into the regulation of a carbohydrate ATP binding cassette transporter from Lactobacillus casei BL23 by the signal transducing protein P-Ser46-HPr. Mol. Microbiol., 105, 2017
1TT2	Cryogenic crystal structure of Staphylococcal nuclease variant truncated Delta+PHS I92K 分子名称: CALCIUM ION, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Nguyen, D.M, Reynald, R.L, Gittis, A.G, Lattman, E.E. 登録日 2004-06-21 公開日 2004-07-06 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 X-ray and thermodynamic studies of staphylococcal nuclease variants I92E and I92K: insights into polarity of the protein interior J.Mol.Biol., 341, 2004
5LX1	Cys-Gly dipeptidase GliJ mutant D304A 分子名称: Dipeptidase, FE (III) ION, GLYCEROL 著者 Huber, E.M, Groll, M. 登録日 2016-09-19 公開日 2017-05-31 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Gliotoxin Biosynthesis: Structure, Mechanism, and Metal Promiscuity of Carboxypeptidase GliJ. ACS Chem. Biol., 12, 2017
1FXH	MUTANT OF PENICILLIN ACYLASE IMPAIRED IN CATALYSIS WITH PHENYLACETIC ACID IN THE ACTIVE SITE 分子名称: 2-PHENYLACETIC ACID, CALCIUM ION, PENICILLIN ACYLASE 著者 Alkema, W.B, Hensgens, C.M, Kroezinga, E.H, de Vries, E, Floris, R, van der Laan, J.M, Dijkstra, B.W, Janssen, D.B. 登録日 2000-09-26 公開日 2001-03-28 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Characterization of the beta-lactam binding site of penicillin acylase of Escherichia coli by structural and site-directed mutagenesis studies. Protein Eng., 13, 2000

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