3OKV
| Human Carbonic Anhydrase II A65S, N67Q (CA IX mimic) bound with 2-Ethylestrone 3-O-sulfamate | 分子名称: | (9beta)-2-ethyl-17-oxoestra-1(10),2,4-trien-3-yl sulfamate, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... | 著者 | Sippel, K.H, Stander, B.A, Robbins, A.H, Tu, C.K, Agbandje-McKenna, M, Silverman, D.N, Joubert, A.M, McKenna, R. | 登録日 | 2010-08-25 | 公開日 | 2011-07-06 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Characterization of Carbonic Anhydrase Isozyme Specific Inhibition by Sulfamated 2-Ethylestra Compounds LETT.DRUG DES.DISCOVERY, 8, 2011
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2F7M
| Crystal Structure of Unliganded Human FPPS | 分子名称: | Farnesyl Diphosphate Synthase, PHOSPHATE ION | 著者 | Rondeau, J.-M, Bitsch, F, Bourgier, E, Geiser, M, Hemmig, R, Kroemer, M, Lehmann, S, Ramage, P, Rieffel, S, Strauss, A, Green, J.R, Jahnke, W. | 登録日 | 2005-12-01 | 公開日 | 2006-02-28 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs. Chemmedchem, 1, 2006
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2XWU
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2LLH
| NMR structure of Npm1_c70 | 分子名称: | Nucleophosmin | 著者 | Banci, L, Bertini, I, Brunori, M, Di Matteo, A, Federici, L, Gallo, A, Lo Sterzo, C, Mori, M. | 登録日 | 2011-11-09 | 公開日 | 2012-06-27 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of Nucleophosmin DNA-binding Domain and Analysis of Its Complex with a G-quadruplex Sequence from the c-MYC Promoter. J.Biol.Chem., 287, 2012
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1JY0
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1BZ1
| HEMOGLOBIN (ALPHA + MET) VARIANT | 分子名称: | PROTEIN (HEMOGLOBIN ALPHA CHAIN), PROTEIN (HEMOGLOBIN BETA CHAIN), PROTOPORPHYRIN IX CONTAINING FE | 著者 | Kavanaugh, J.S, Arnone, A. | 登録日 | 1998-11-05 | 公開日 | 1998-11-11 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Structural and functional properties of human hemoglobins reassembled after synthesis in Escherichia coli. Biochemistry, 38, 1999
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3BTM
| THE CRYSTAL STRUCTURES OF THE COMPLEXES BETWEEN BOVINE BETA-TRYPSIN AND TEN P1 VARIANTS OF BPTI | 分子名称: | CALCIUM ION, PROTEIN (PANCREATIC TRYPSIN INHIBITOR), PROTEIN (TRYPSIN), ... | 著者 | Helland, R, Otlewski, J, Sundheim, O, Dadlez, M, Smalas, A.O. | 登録日 | 1999-03-10 | 公開日 | 2000-03-13 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The crystal structures of the complexes between bovine beta-trypsin and ten P1 variants of BPTI. J.Mol.Biol., 287, 1999
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3BTF
| THE CRYSTAL STRUCTURES OF THE COMPLEXES BETWEEN BOVINE BETA-TRYPSIN AND TEN P1 VARIANTS OF BPTI. | 分子名称: | CALCIUM ION, PROTEIN (PANCREATIC TRYPSIN INHIBITOR), PROTEIN (TRYPSIN), ... | 著者 | Helland, R, Otlewski, J, Sundheim, O, Dadlez, M, Smalas, A.O. | 登録日 | 1999-03-10 | 公開日 | 2000-03-13 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The crystal structures of the complexes between bovine beta-trypsin and ten P1 variants of BPTI. J.Mol.Biol., 287, 1999
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1RH0
| Crystal structure of human Tyrosyl-DNA Phosphodiesterase complexed with vanadate, octopamine and trinucleotide GTT | 分子名称: | 4-(2S-AMINO-1-HYDROXYETHYL)PHENOL, 5'-D(*GP*TP*T)-3', SPERMINE, ... | 著者 | Davies, D.R, Interthal, H, Champoux, J.J, Hol, W.G. | 登録日 | 2003-11-13 | 公開日 | 2004-03-02 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Explorations of peptide and oligonucleotide binding sites of tyrosyl-DNA phosphodiesterase using vanadate complexes. J.Med.Chem., 47, 2004
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2F89
| Crystal structure of human FPPS in complex with pamidronate | 分子名称: | Farnesyl Diphosphate Synthase, MANGANESE (II) ION, PAMIDRONATE, ... | 著者 | Rondeau, J.-M, Bitsch, F, Bourgier, E, Geiser, M, Hemmig, R, Kroemer, M, Lehmann, S, Ramage, P, Rieffel, S, Strauss, A, Green, J.R, Jahnke, W. | 登録日 | 2005-12-02 | 公開日 | 2006-02-28 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs. Chemmedchem, 1, 2006
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2F94
| Crystal structure of human FPPS in complex with ibandronate | 分子名称: | Farnesyl Diphosphate Synthase, IBANDRONATE, PHOSPHATE ION, ... | 著者 | Rondeau, J.-M, Bitsch, F, Bourgier, E, Geiser, M, Hemmig, R, Kroemer, M, Lehmann, S, Ramage, P, Rieffel, S, Strauss, A, Green, J.R, Jahnke, W. | 登録日 | 2005-12-05 | 公開日 | 2006-02-28 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs. Chemmedchem, 1, 2006
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3AZK
| Crystal Structure of Human Nucleosome Core Particle Containing H4K59Q mutation | 分子名称: | 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ... | 著者 | Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H. | 登録日 | 2011-05-25 | 公開日 | 2011-09-21 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains Biochemistry, 50, 2011
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3BTD
| The Crystal Structures of the Complexes Between the Bovine Beta-Trypsin and Ten P1 Variants of BPTI. | 分子名称: | CALCIUM ION, PROTEIN (BOVINE PANCREATIC TRYPSIN INHIBITOR), PROTEIN (TRYPSIN), ... | 著者 | Helland, R, Otlewski, J, Sundheim, O, Dadlez, M, Smalas, A.O. | 登録日 | 1999-03-11 | 公開日 | 2000-03-13 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The crystal structures of the complexes between bovine beta-trypsin and ten P1 variants of BPTI. J.Mol.Biol., 287, 1999
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1HU3
| MIDDLE DOMAIN OF HUMAN EIF4GII | 分子名称: | EIF4GII | 著者 | Marcotrigiano, J, Lomakin, I, Pestova, T.V, Hellen, C.U.T, Sonenberg, N, Burley, S.K. | 登録日 | 2001-01-03 | 公開日 | 2001-02-21 | 最終更新日 | 2021-02-03 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | A conserved HEAT domain within eIF4G directs assembly of the translation initiation machinery. Mol.Cell, 7, 2001
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1RV6
| Crystal Structure of PlGF in Complex with Domain 2 of VEGFR1 | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FLT1 protein, placenta growth factor (PlGF) | 著者 | Christinger, H.W, Fuh, G, de Vos, A.M, Wiesmann, C. | 登録日 | 2003-12-12 | 公開日 | 2004-01-20 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | The crystal structure of placental growth factor in complex with domain 2 of vascular endothelial growth factor receptor-1. J.Biol.Chem., 279, 2004
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1WA4
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3BTE
| The Crystal Structures of the Complexes Between Bovine Beta-Trypsin and Ten P1 Variants of BPTI. | 分子名称: | CALCIUM ION, PANCREATIC TRYPSIN INHIBITOR, SULFATE ION, ... | 著者 | Helland, R, Otlewski, J, Sundheim, O, Dadlez, M, Smalas, A.O. | 登録日 | 1999-03-11 | 公開日 | 2000-03-15 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | The crystal structures of the complexes between bovine beta-trypsin and ten P1 variants of BPTI. J.Mol.Biol., 287, 1999
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3BTG
| THE CRYSTAL STRUCTURES OF THE COMPLEXES BETWEEN BOVINE BETA-TRYPSIN AND TEN P1 VARIANTS OF BPTI | 分子名称: | CALCIUM ION, PROTEIN (PANCREATIC TRYPSIN INHIBITOR), PROTEIN (TRYPSIN), ... | 著者 | Helland, R, Otlewski, J, Sundheim, O, Dadlez, M, Smalas, A.O. | 登録日 | 1999-03-10 | 公開日 | 2000-03-13 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The crystal structures of the complexes between bovine beta-trypsin and ten P1 variants of BPTI. J.Mol.Biol., 287, 1999
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1YGK
| Crystal Structure of Pyridoxal Kinase in Complex with Roscovitine and Derivatives | 分子名称: | Pyridoxal kinase, R-ROSCOVITINE | 著者 | Tang, L, Li, M.-H, Cao, P, Wang, F, Chang, W.-R, Bach, S, Reinhardt, J, Ferandin, Y, Koken, M, Galons, H, Wan, Y, Gray, N, Meijer, L, Jiang, T, Liang, D.-C. | 登録日 | 2005-01-05 | 公開日 | 2005-07-05 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of pyridoxal kinase in complex with roscovitine and derivatives J.Biol.Chem., 280, 2005
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4B1U
| Structure of the Phactr1 RPEL domain and RPEL motif directed assemblies with G-actin reveal the molecular basis for actin binding cooperativity. | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACTIN, ALPHA SKELETAL MUSCLE, ... | 著者 | Mouilleron, S, Wiezlak, M, O'Reilly, N, Treisman, R, McDonald, N.Q. | 登録日 | 2012-07-12 | 公開日 | 2013-07-31 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structures of the Phactr1 RPEL domain and RPEL motif complexes with G-actin reveal the molecular basis for actin binding cooperativity. Structure, 20, 2012
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1T2D
| Plasmodium falciparum lactate dehydrogenase complexed with NAD+ and oxalate | 分子名称: | GLYCEROL, L-lactate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Cameron, A, Read, J, Tranter, R, Winter, V.J, Sessions, R.B, Brady, R.L, Vivas, L, Easton, A, Kendrick, H, Croft, S.L, Barros, D, Lavandera, J.L, Martin, J.J, Risco, F, Garcia-Ochoa, S, Gamo, F.J, Sanz, L, Leon, L, Ruiz, J.R, Gabarro, R, Mallo, A, De Las Heras, F.G. | 登録日 | 2004-04-21 | 公開日 | 2004-05-11 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity. J.Biol.Chem., 279, 2004
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2F8C
| Crystal structure of FPPS in complex with Zoledronate | 分子名称: | Farnesyl Diphosphate Synthase, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Rondeau, J.-M, Bitsch, F, Bourgier, E, Geiser, M, Hemmig, R, Kroemer, M, Lehmann, S, Ramage, P, Rieffel, S, Strauss, A, Green, J.R, Jahnke, W. | 登録日 | 2005-12-02 | 公開日 | 2006-02-28 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs. Chemmedchem, 1, 2006
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2F92
| Crystal structure of human FPPS in complex with alendronate | 分子名称: | 4-AMINO-1-HYDROXYBUTANE-1,1-DIYLDIPHOSPHONATE, Farnesyl Diphosphate Synthase, PHOSPHATE ION, ... | 著者 | Rondeau, J.-M, Bitsch, F, Bourgier, E, Geiser, M, Hemmig, R, Kroemer, M, Lehmann, S, Ramage, P, Rieffel, S, Strauss, A, Green, J.R, Jahnke, W. | 登録日 | 2005-12-05 | 公開日 | 2006-02-28 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs. Chemmedchem, 1, 2006
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2F8Z
| Crystal structure of human FPPS in complex with zoledronate and isopentenyl diphosphate | 分子名称: | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Farnesyl Diphosphate Synthase, MAGNESIUM ION, ... | 著者 | Rondeau, J.-M, Bitsch, F, Bourgier, E, Geiser, M, Hemmig, R, Kroemer, M, Lehmann, S, Ramage, P, Rieffel, S, Strauss, A, Green, J.R, Jahnke, W. | 登録日 | 2005-12-02 | 公開日 | 2006-02-28 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs. Chemmedchem, 1, 2006
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1SSL
| Solution structure of the PSI domain from the Met receptor | 分子名称: | Hepatocyte growth factor receptor | 著者 | Kozlov, G, Perreault, A, Schrag, J.D, Cygler, M, Gehring, K, Ekiel, I. | 登録日 | 2004-03-24 | 公開日 | 2004-10-12 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Insights into function of PSI domains from structure of the Met receptor PSI domain. Biochem.Biophys.Res.Commun., 321, 2004
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