5KXS
| Hen Egg White Lysozyme at 278K, Data set 4 | 分子名称: | Lysozyme C, SODIUM ION | 著者 | Russi, S, Gonzalez, A, Kenner, L.R, Keedy, D.A, Fraser, J.S, van den Bedem, H. | 登録日 | 2016-07-20 | 公開日 | 2016-09-07 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Conformational variation of proteins at room temperature is not dominated by radiation damage. J Synchrotron Radiat, 24, 2017
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5KXX
| Hen Egg White Lysozyme at 278K, Data set 7 | 分子名称: | Lysozyme C, SODIUM ION | 著者 | Russi, S, Gonzalez, A, Kenner, L.R, Keedy, D.A, Fraser, J.S, van den Bedem, H. | 登録日 | 2016-07-20 | 公開日 | 2016-09-07 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Conformational variation of proteins at room temperature is not dominated by radiation damage. J Synchrotron Radiat, 24, 2017
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5KXO
| Hen Egg White Lysozyme at 278K, Data set 1 | 分子名称: | Lysozyme C, SODIUM ION | 著者 | Russi, S, Gonzalez, A, Kenner, L.R, Keedy, D.A, Fraser, J.S, van den Bedem, H. | 登録日 | 2016-07-20 | 公開日 | 2016-09-07 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Conformational variation of proteins at room temperature is not dominated by radiation damage. J Synchrotron Radiat, 24, 2017
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5KXZ
| Hen Egg White Lysozyme at 278K, Data set 9 | 分子名称: | Lysozyme C, SODIUM ION | 著者 | Russi, S, Gonzalez, A, Kenner, L.R, Keedy, D.A, Fraser, J.S, van den Bedem, H. | 登録日 | 2016-07-20 | 公開日 | 2016-09-07 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Conformational variation of proteins at room temperature is not dominated by radiation damage. J Synchrotron Radiat, 24, 2017
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5KXW
| Hen Egg White Lysozyme at 278K, Data set 6 | 分子名称: | Lysozyme C, SODIUM ION | 著者 | Russi, S, Gonzalez, A, Kenner, L.R, Keedy, D.A, Fraser, J.S, van den Bedem, H. | 登録日 | 2016-07-20 | 公開日 | 2016-09-07 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Conformational variation of proteins at room temperature is not dominated by radiation damage. J Synchrotron Radiat, 24, 2017
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8GBN
| Structure of Apo Human SIRT5 P114T Mutant | 分子名称: | 1,2-ETHANEDIOL, NAD-dependent protein deacylase sirtuin-5, mitochondrial, ... | 著者 | Petrunak, E.M, Stuckey, J.A. | 登録日 | 2023-02-26 | 公開日 | 2024-06-05 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Human SIRT5 variants with reduced stability and activity do not cause neuropathology in mice. Iscience, 27, 2024
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8GBL
| Structure of Apo Human SIRT5 | 分子名称: | NAD-dependent protein deacylase sirtuin-5, mitochondrial, ZINC ION | 著者 | Petrunak, E.M, Stuckey, J.A. | 登録日 | 2023-02-26 | 公開日 | 2024-06-05 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Human SIRT5 variants with reduced stability and activity do not cause neuropathology in mice. Iscience, 27, 2024
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5NUK
| Engineered beta-lactoglobulin: variant I56F-L39A-M107F in complex with chlorpromazine (LG-FAF-CLP) | 分子名称: | 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine, Beta-lactoglobulin, CHLORIDE ION, ... | 著者 | Loch, J.I, Bonarek, P, Tworzydlo, M, Lazinska, I, Szydlowska, J, Lewinski, K. | 登録日 | 2017-04-30 | 公開日 | 2018-04-04 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The engineered beta-lactoglobulin with complementarity to the chlorpromazine chiral conformers. Int. J. Biol. Macromol., 114, 2018
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6D2T
| HLA-B*57:01 presenting LALLTGVRW | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-57 alpha chain, ... | 著者 | Vivian, J.P, Rossjohn, J. | 登録日 | 2018-04-13 | 公開日 | 2018-10-03 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands. Sci Immunol, 3, 2018
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6D29
| HLA-B*57:01 presenting TSMSFVPRPW | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-57 alpha chain, ... | 著者 | Vivian, J.P, Rossjohn, J. | 登録日 | 2018-04-13 | 公開日 | 2018-10-03 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands. Sci Immunol, 3, 2018
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8K82
| Cryo-EM structure of the yeast 80S ribosome with tigecycline, Not5 and P-site tRNA | 分子名称: | 18S rRNA, 23S rRNA, 40S ribosomal protein S1-A, ... | 著者 | Buschauer, R, Beckmann, R, Cheng, J. | 登録日 | 2023-07-28 | 公開日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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7Q85
| Crystal structure of human STING in complex with MD1193 | 分子名称: | 9-[(1R,6R,8R,13E,15R,17R,18R)-17-(6-aminopurin-9-yl)-9,18-bis(fluoranyl)-3,12-bis(oxidanyl)-3,12-bis(oxidanylidene)-2,4,7,11,16-pentaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.3.0.0^{6,10}]octadec-13-en-8-yl]purin-6-amine, Stimulator of interferon genes protein | 著者 | Smola, M, Klima, M, Boura, E. | 登録日 | 2021-11-10 | 公開日 | 2022-10-19 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.359 Å) | 主引用文献 | Vinylphosphonate-based cyclic dinucleotides enhance STING-mediated cancer immunotherapy. Eur.J.Med.Chem., 259, 2023
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8FXV
| Crystal structure of human proTGF-beta2 in complex with Nb18 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody clone 18, Transforming growth factor beta-2 proprotein | 著者 | Le, V.Q, Springer, T.A. | 登録日 | 2023-01-25 | 公開日 | 2023-06-21 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | A specialized integrin-binding motif enables proTGF-beta 2 activation by integrin alpha V beta 6 but not alpha V beta 8. Proc.Natl.Acad.Sci.USA, 120, 2023
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8FXS
| Crystal structure of human pro-TGF-beta2 in complex with Nb9 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody clone 9, Transforming growth factor beta-2 proprotein | 著者 | Le, V.Q, Springer, T.A. | 登録日 | 2023-01-25 | 公開日 | 2023-06-21 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | A specialized integrin-binding motif enables proTGF-beta 2 activation by integrin alpha V beta 6 but not alpha V beta 8. Proc.Natl.Acad.Sci.USA, 120, 2023
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5NFF
| Crystal structure of GP1 receptor binding domain from Morogoro virus | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, ... | 著者 | Israeli, H, Cohen-Dvashi, H, Shulman, A, Shimon, A, Diskin, R. | 登録日 | 2017-03-14 | 公開日 | 2017-04-19 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.615 Å) | 主引用文献 | Mapping of the Lassa virus LAMP1 binding site reveals unique determinants not shared by other old world arenaviruses. PLoS Pathog., 13, 2017
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7ZUC
| Human Major Histocompatibility Complex A2 allele presenting LLLGIGILV | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, LEU-LEU-LEU-GLY-ILE-GLY-ILE-LEU-VAL, ... | 著者 | Rizkallah, P.J, Wall, A, Sewell, A.K, Fuller, A. | 登録日 | 2022-05-12 | 公開日 | 2023-05-24 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy. Cell, 186, 2023
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5MWV
| Solid-state NMR Structure of outer membrane protein G in lipid bilayers | 分子名称: | Outer membrane protein G | 著者 | Retel, J.S, Nieuwkoop, A.J, Hiller, M, Higman, V.A, Barbet-Massin, E, Stanek, J, Andreas, L.B, Franks, W.T, van Rossum, B.-J, Vinothkumar, K.R, Handel, L, de Palma, G.G, Bardiaux, B, Pintacuda, G, Emsley, L, Kuelbrandt, W, Oschkinat, H. | 登録日 | 2017-01-20 | 公開日 | 2017-12-27 | 最終更新日 | 2024-05-15 | 実験手法 | SOLID-STATE NMR | 主引用文献 | Structure of outer membrane protein G in lipid bilayers. Nat Commun, 8, 2017
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5O60
| Structure of the 50S large ribosomal subunit from Mycobacterium smegmatis | 分子名称: | 23S rRNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ... | 著者 | Hentschel, J, Burnside, C, Mignot, I, Leibundgut, M, Boehringer, D, Ban, N. | 登録日 | 2017-06-02 | 公開日 | 2017-07-12 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | 主引用文献 | The Complete Structure of the Mycobacterium smegmatis 70S Ribosome. Cell Rep, 20, 2017
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7VUN
| Design, modification, evaluation and cocrystal studies of novel phthalimides regulating PD-1/PD-L1 interaction | 分子名称: | (2~{S},3~{S})-2-[[6-[(3-cyanophenyl)methoxy]-2-(2-methyl-3-phenyl-phenyl)-1,3-bis(oxidanylidene)isoindol-5-yl]methylamino]-3-oxidanyl-butanoic acid, Programmed cell death 1 ligand 1 | 著者 | Cheng, Y, Sun, C.L, Chen, M.R, Yang, P, Xiao, Y.B. | 登録日 | 2021-11-03 | 公開日 | 2022-09-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.701 Å) | 主引用文献 | Novel phthalimides regulating PD-1/PD-L1 interaction as potential immunotherapy agents. Acta Pharm Sin B, 12, 2022
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6D2B
| HLA-B*57:01 presenting LSDSTARDVTW | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-57 alpha chain, ... | 著者 | Vivian, J.P, Rossjohn, J. | 登録日 | 2018-04-13 | 公開日 | 2018-10-03 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands. Sci Immunol, 3, 2018
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4U79
| Crystal structure of human JNK3 in complex with a benzenesulfonamide inhibitor. | 分子名称: | Mitogen-activated protein kinase 10, N-{4-[(3-{2-[(trans-4-aminocyclohexyl)amino]pyrimidin-4-yl}pyridin-2-yl)oxy]naphthalen-1-yl}benzenesulfonamide | 著者 | Mohr, C. | 登録日 | 2014-07-30 | 公開日 | 2014-10-08 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Unfolded Protein Response in Cancer: IRE1 alpha Inhibition by Selective Kinase Ligands Does Not Impair Tumor Cell Viability. Acs Med.Chem.Lett., 6, 2015
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3V7E
| Crystal structure of YbxF bound to the SAM-I riboswitch aptamer | 分子名称: | COBALT HEXAMMINE(III), MAGNESIUM ION, Ribosome-associated protein L7Ae-like, ... | 著者 | Baird, N.J, Zhang, J, Hamma, T, Ferre-D'Amare, A.R. | 登録日 | 2011-12-21 | 公開日 | 2012-03-07 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | YbxF and YlxQ are bacterial homologs of L7Ae and bind K-turns but not K-loops. Rna, 18, 2012
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6MSU
| Integrin alphaVBeta3 in complex with EETI-II 2.5F | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | van Agthoven, J.F, Arnaout, M.A. | 登録日 | 2018-10-18 | 公開日 | 2019-10-23 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | 主引用文献 | Structural Basis of the Differential Binding of Engineered Knottins to Integrins alpha V beta 3 and alpha 5 beta 1. Structure, 27, 2019
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5U7A
| Crystal structure of a complex formed between MerB and Dimethyltin | 分子名称: | Alkylmercury lyase, BROMIDE ION, Dimethyltin dibromide, ... | 著者 | Wahba, H.M, Stevenson, M, Mansour, A, Sygusch, J, Wilcox, D.E, Omichinski, J.G. | 登録日 | 2016-12-12 | 公開日 | 2017-01-11 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.532 Å) | 主引用文献 | Structural and Biochemical Characterization of Organotin and Organolead Compounds Binding to the Organomercurial Lyase MerB Provide New Insights into Its Mechanism of Carbon-Metal Bond Cleavage. J. Am. Chem. Soc., 139, 2017
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5U88
| Crystal structure of a MerB-triimethyllead complex. | 分子名称: | ACETATE ION, Alkylmercury lyase, Trimethyllead bromide | 著者 | Wahba, H.M, Stevenson, M, Mansour, A, Sygusch, J, Wilcox, D.E, Omichinski, J.G. | 登録日 | 2016-12-14 | 公開日 | 2017-01-11 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | 主引用文献 | Structural and Biochemical Characterization of Organotin and Organolead Compounds Binding to the Organomercurial Lyase MerB Provide New Insights into Its Mechanism of Carbon-Metal Bond Cleavage. J. Am. Chem. Soc., 139, 2017
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