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8URV
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Solution NMR structure of pro-IL-18
分子名称: Interleukin-18
著者Bonin, J.P, Aramini, J.M, Kay, L.E.
登録日2023-10-26
公開日2024-05-29
実験手法SOLUTION NMR
主引用文献Structural transitions enable interleukin-18 maturation and signaling.
Immunity, 2024
8URU
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Spo11 core complex with hairpin DNA
分子名称: Antiviral protein SKI8, Hairpin DNA, MAGNESIUM ION, ...
著者Yu, Y, Patel, D.J.
登録日2023-10-26
公開日2024-06-26
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM structure of the yeast Spo11 core complex bound to DNA
To Be Published
8URQ
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Spo11 core complex with gapped DNA
分子名称: Antiviral protein SKI8, MAGNESIUM ION, Meiosis-specific protein SPO11, ...
著者Yu, Y, Patel, D.J.
登録日2023-10-26
公開日2024-06-26
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structure of the yeast Spo11 core complex bound to DNA
To Be Published
8URN
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Crystal structure of EscI(51-87)-linker-EtgA(18-152) fusion protein
分子名称: EscI inner rod protein type III secretion system,EtgA protein, SULFATE ION
著者van den Akker, F.
登録日2023-10-26
公開日2024-02-14
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Structural insights into peptidoglycan glycosidase EtgA binding to the inner rod protein EscI of the type III secretion system via a designed EscI-EtgA fusion protein.
Protein Sci., 33, 2024
8URI
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Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH bound to ops signal, NusA, mRNA with a 27 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
著者Molodtsov, V, Wang, C, Ebright, R.H.
登録日2023-10-26
公開日2024-05-29
実験手法ELECTRON MICROSCOPY (5.3 Å)
主引用文献Escherichia coli transcription-translation coupled complex class A (TTC-A) containing RfaH bound to ops signal, mRNA with a 21 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome
Nat.Struct.Mol.Biol., 2024
8URH
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BU of 8urh by Molmil
Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH bound to ops signal, mRNA with a 27 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
著者Molodtsov, V, Wang, C, Ebright, R.H.
登録日2023-10-26
公開日2024-05-29
実験手法ELECTRON MICROSCOPY (5.7 Å)
主引用文献Escherichia coli transcription-translation coupled complex class A (TTC-A) containing RfaH bound to ops signal, mRNA with a 21 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome
Nat.Struct.Mol.Biol., 2024
8URF
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Crystal Structure of human ASGR2 CRD (Carbohydrate Recognition Domain) bound to 8G8 Fab
分子名称: 8G8 Fab Heavy Chain, 8G8 Fab Light Chain, Asialoglycoprotein receptor 2, ...
著者Sampathumar, P, Li, Y.
登録日2023-10-25
公開日2024-06-19
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Targeted protein degradation systems to enhance Wnt signaling.
Elife, 13, 2024
8URB
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Porcine epidemic diarrhea virus complete core polymerase complex
分子名称: RNA (33-MER), RNA (55-MER), ZINC ION, ...
著者Anderson, T.K, Kirchdoerfer, R.N.
登録日2023-10-25
公開日2023-11-15
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献An alphacoronavirus polymerase structure reveals conserved co-factor functions.
Biorxiv, 2023
8UR9
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Crystal Structure of the SARS-CoV-2 Main Protease in Complex with Compound 61
分子名称: (5P)-5-[(1P,3M,3'P)-3-{3-chloro-5-[(2-chlorophenyl)methoxy]-4-fluorophenyl}-2-oxo-2H-[1,3'-bipyridin]-5-yl]-1-methylpyrimidine-2,4(1H,3H)-dione, 3C-like proteinase nsp5
著者Papini, C, Zhang, C.H, Jorgensen, W.L, Anderson, K.S.
登録日2023-10-25
公開日2024-05-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Proof-of-concept studies with a computationally designed M pro inhibitor as a synergistic combination regimen alternative to Paxlovid.
Proc.Natl.Acad.Sci.USA, 121, 2024
8UR7
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I53_dn5 nanoparticle displaying the trimeric HA heads with heptad domain, TH-6heptad-I53_dn5 (local refinement of TH-6heptad)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Trimer head HA,Hemagglutinin HA1 chain
著者Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2023-10-25
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Antigen spacing on protein nanoparticles influences antibody responses to vaccination.
Cell Rep, 42, 2023
8UR6
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Cryo-EM reconstruction of Staphylococcus aureus oleate hydratase (OhyA) dimer with a disordered C-terminal membrane-association domain
分子名称: Oleate hydratase
著者Oldham, M.L, Qayyum, M.Z.
登録日2023-10-25
公開日2024-01-10
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献The carboxy terminus causes interfacial assembly of oleate hydratase on a membrane bilayer.
J.Biol.Chem., 300, 2024
8UR5
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I53_dn5 nanoparticle displaying the trimeric HA heads with heptad domain, TH-1heptad-I53_dn5 (local refinement of TH-1heptad)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Trimer head HA,Hemagglutinin HA1 chain
著者Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2023-10-25
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Antigen spacing on protein nanoparticles influences antibody responses to vaccination.
Cell Rep, 42, 2023
8UR4
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Crystal Structure of macrophage migration inhibitory factor (MIF) from Trichomonas vaginalis (I4122 form)
分子名称: CHLORIDE ION, MACROPHAGE MIGRATION INHIBITORY FACTOR
著者Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2023-10-25
公開日2024-03-20
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal Structure of macrophage migration inhibitory factor (MIF) from Trichomonas vaginalis (I4122 form)
To be published
8UR3
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Cryo-EM reconstruction of Staphylococcus aureus Oleate hydratase (OhyA) dimer with an ordered C-terminal membrane-association domain
分子名称: Oleate hydratase
著者Oldham, M.L, Qayyum, M.Z.
登録日2023-10-25
公開日2024-01-10
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.61 Å)
主引用文献The carboxy terminus causes interfacial assembly of oleate hydratase on a membrane bilayer.
J.Biol.Chem., 300, 2024
8UR2
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Crystal Structure of macrophage migration inhibitory factor (MIF) from Trichomonas vaginalis (I41 form)
分子名称: IODIDE ION, MACROPHAGE MIGRATION INHIBITORY FACTOR, PYRUVIC ACID
著者Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2023-10-25
公開日2023-11-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of macrophage migration inhibitory factor (MIF) from Trichomonas vaginalis (I41 form)
To be published
8UR1
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BU of 8ur1 by Molmil
Crystal structure N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (pyruvate bound halide free active site)
分子名称: CHLORIDE ION, GLYCEROL, N-acetylneuraminate lyase, ...
著者Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2023-10-25
公開日2023-11-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (pyruvate bound halide free active site)
To be published
8UR0
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Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH bound to ops signal, NusA, mRNA with a 24 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
著者Molodtsov, V, Wang, C, Ebright, R.H.
登録日2023-10-25
公開日2024-05-29
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Escherichia coli transcription-translation coupled complex class A (TTC-A) containing RfaH bound to ops signal, mRNA with a 21 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome
Nat.Struct.Mol.Biol., 2024
8UQZ
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Round 18 Arylesterase Variant of Phosphotriesterase Bound to Gadolinium(III) Measured at 9.5 keV
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, GADOLINIUM ION, ...
著者Breeze, C.W, Frkic, R.L, Campbell, E.C, Jackson, C.J.
登録日2023-10-25
公開日2024-04-03
最終更新日2024-04-10
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Mononuclear binding and catalytic activity of europium(III) and gadolinium(III) at the active site of the model metalloenzyme phosphotriesterase.
Acta Crystallogr D Struct Biol, 80, 2024
8UQY
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Round 18 Arylesterase Variant of Phosphotriesterase Bound to Europium(III) Measured at 9.5 keV
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, EUROPIUM (III) ION, ...
著者Breeze, C.W, Frkic, R.L, Campbell, E.C, Jackson, C.J.
登録日2023-10-25
公開日2024-04-03
最終更新日2024-04-10
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Mononuclear binding and catalytic activity of europium(III) and gadolinium(III) at the active site of the model metalloenzyme phosphotriesterase.
Acta Crystallogr D Struct Biol, 80, 2024
8UQX
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Round 18 Arylesterase Variant of Apo-Phosphotriesterase Measured at 9.5 keV
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Phosphotriesterase variant PTE-R18
著者Breeze, C.W, Frkic, R.L, Campbell, E.C, Jackson, C.J.
登録日2023-10-25
公開日2024-04-03
最終更新日2024-04-10
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Mononuclear binding and catalytic activity of europium(III) and gadolinium(III) at the active site of the model metalloenzyme phosphotriesterase.
Acta Crystallogr D Struct Biol, 80, 2024
8UQW
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Round 18 Arylesterase Variant of Apo-Phosphotriesterase Measured at 13 keV
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Phosphotriesterase variant PTE-R18
著者Breeze, C.W, Frkic, R.L, Campbell, E.C, Jackson, C.J.
登録日2023-10-25
公開日2024-04-03
最終更新日2024-04-10
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Mononuclear binding and catalytic activity of europium(III) and gadolinium(III) at the active site of the model metalloenzyme phosphotriesterase.
Acta Crystallogr D Struct Biol, 80, 2024
8UQV
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Trehalose Synthase (TreS) of Mycobacterium tuberculosis in complex with 6-TreAz compound
分子名称: 6-azido-6-deoxy-alpha-D-glucopyranose, CALCIUM ION, Trehalose synthase/amylase TreS, ...
著者Pathirage, R, Ronning, D.R.
登録日2023-10-24
公開日2024-03-27
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Targeting Mycobacterium tuberculosis Persistence through Inhibition of the Trehalose Catalytic Shift.
Acs Infect Dis., 10, 2024
8UQT
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Crystal structure of the Tree Shrew p53 tetramerization domain
分子名称: Cellular tumor antigen p53, SULFATE ION
著者Wahba, H.M, Sakaguchi, S, Nakagawa, N, Wada, J, Kamada, R, Sakaguchi, K, Omichinski, J.G.
登録日2023-10-24
公開日2023-12-20
実験手法X-RAY DIFFRACTION (1.16 Å)
主引用文献Highly Similar Tetramerization Domains from the p53 Protein of Different Mammalian Species Possess Varying Biophysical, Functional and Structural Properties.
Int J Mol Sci, 24, 2023
8UQS
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Crystal structure of the Opossum p53 tetramerization domain
分子名称: Cellular tumor antigen p53 (Fragment)
著者Wahba, H.M, Sakaguchi, S, Nakagawa, N, Wada, J, Kamada, R, Sakaguchi, K, Omichinski, J.G.
登録日2023-10-24
公開日2023-12-20
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Highly Similar Tetramerization Domains from the p53 Protein of Different Mammalian Species Possess Varying Biophysical, Functional and Structural Properties.
Int J Mol Sci, 24, 2023
8UQR
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Crystal structure of the human p53 tetramerization domain
分子名称: Cellular tumor antigen p53
著者Wahba, H.M, Sakaguchi, S, Nakagawa, N, Wada, J, Kamada, R, Sakaguchi, K, Omichinski, J.G.
登録日2023-10-24
公開日2023-12-20
実験手法X-RAY DIFFRACTION (1.22 Å)
主引用文献Highly Similar Tetramerization Domains from the p53 Protein of Different Mammalian Species Possess Varying Biophysical, Functional and Structural Properties.
Int J Mol Sci, 24, 2023

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件を2024-06-26に公開中

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