8UQR

Crystal structure of the human p53 tetramerization domain

Summary for 8UQR

• Entry DOI: 10.2210/pdb8uqr/pdb
• Descriptor: Cellular tumor antigen p53 (2 entities in total)
• Functional Keywords: human p53 tetramerization domain stability, transcription
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 15641.40

Authors

Wahba, H.M.,Sakaguchi, S.,Nakagawa, N.,Wada, J.,Kamada, R.,Sakaguchi, K.,Omichinski, J.G. (deposition date: 2023-10-24, release date: 2023-12-20)

• Primary citation: Sakaguchi, S.,Nakagawa, N.,Wahba, H.M.,Wada, J.,Kamada, R.,Omichinski, J.G.,Sakaguchi, K.; Highly Similar Tetramerization Domains from the p53 Protein of Different Mammalian Species Possess Varying Biophysical, Functional and Structural Properties.; Int J Mol Sci, 24:-, 2023; PubMed: 38068946; DOI: 10.3390/ijms242316620

Experimental method

X-RAY DIFFRACTION (1.22 Å)