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3CZ7
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Molecular Basis for the Autoregulation of the Protein Acetyl Transferase Rtt109
分子名称: ACETYL COENZYME *A, Regulator of Ty1 transposition protein 109
著者Hoelz, A, Stavropoulos, P.
登録日2008-04-28
公開日2008-09-09
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular basis for the autoregulation of the protein acetyl transferase Rtt109
Proc.Natl.Acad.Sci.Usa, 105, 2008
4Z0M
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BU of 4z0m by Molmil
EchA5 Mycobacterium tuberculosis
分子名称: Enoyl-CoA hydratase
著者Chaudhary, S, Gokhale, R.S.
登録日2015-03-26
公開日2016-02-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Unsaturated Lipid Assimilation by Mycobacteria Requires Auxiliary cis-trans Enoyl CoA Isomerase
Chem.Biol., 22, 2015
3LWT
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BU of 3lwt by Molmil
Crystal structure of the Yeast Sac1: Implications for its phosphoinositide phosphatase function
分子名称: Phosphoinositide phosphatase SAC1
著者Mao, Y, Manford, A, Xia, T, Saxena, A.K, Stefan, C, Hu, F, Emr, S.D.
登録日2010-02-24
公開日2010-05-05
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.956 Å)
主引用文献Crystal structure of the yeast Sac1: implications for its phosphoinositide phosphatase function.
Embo J., 29, 2010
1ERW
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BU of 1erw by Molmil
HUMAN THIOREDOXIN DOUBLE MUTANT WITH CYS 32 REPLACED BY SER AND CYS 35 REPLACED BY SER
分子名称: THIOREDOXIN
著者Weichsel, A, Gasdaska, J.R, Powis, G, Montfort, W.R.
登録日1996-02-07
公開日1996-10-14
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structures of reduced, oxidized, and mutated human thioredoxins: evidence for a regulatory homodimer.
Structure, 4, 1996
4Z0X
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BU of 4z0x by Molmil
Structure of Hepatitis C Virus Envelope glycoprotein E2 antigenic region 434-446 bound to the broadly neutralizing antibody HC26AM
分子名称: Antibody HC26AM heavy chain variable domain, Antibody HC26AM light chain variable domain, HCV E2 Antigen (residues 432-446)
著者Rangarajan, S, Shahid, S, Mariuzza, R.A.
登録日2015-03-26
公開日2016-07-20
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Affinity maturation of a broadly neutralizing human monoclonal antibody that prevents acute hepatitis C virus infection in mice.
Hepatology, 64, 2016
2CTJ
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BU of 2ctj by Molmil
Solution structure of the 8th KH type I domain from human Vigilin
分子名称: Vigilin
著者Tomizawa, T, Kigawa, T, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-24
公開日2005-11-24
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the 8th KH type I domain from human Vigilin
To be Published
4KLM
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BU of 4klm by Molmil
DNA polymerase beta matched product complex with Mg2+, 11 h
分子名称: 5'-D(*CP*CP*GP*AP*CP*GP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*C)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ...
著者Freudenthal, B.D, Beard, W.A, Shock, D.D, Wilson, S.H.
登録日2013-05-07
公開日2013-07-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.747 Å)
主引用文献Observing a DNA polymerase choose right from wrong.
Cell(Cambridge,Mass.), 154, 2013
6WSL
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Cryo-EM structure of VASH1-SVBP bound to microtubules
分子名称: GUANOSINE-5'-TRIPHOSPHATE, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Small vasohibin-binding protein, ...
著者Li, F, Li, Y, Yu, H.
登録日2020-05-01
公開日2020-08-26
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM structure of VASH1-SVBP bound to microtubules.
Elife, 9, 2020
3V6O
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Leptin Receptor-antibody complex
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
著者Carpenter, B, Hemsworth, G.R, Ross, R.J, Artymiuk, P.J.
登録日2011-12-20
公開日2012-03-14
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure of the human obesity receptor leptin-binding domain reveals the mechanism of leptin antagonism by a monoclonal antibody.
Structure, 20, 2012
7ZCU
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BU of 7zcu by Molmil
PucA-LH2 complex from Rps. palustris
分子名称: 1,2-Dihydro-psi,psi-caroten-1-ol, BACTERIOCHLOROPHYLL A, Light-harvesting protein B-800-850 alpha chain, ...
著者Qian, P, Cogdell, R.J.
登録日2022-03-28
公開日2022-10-12
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Cryo-EM structures of light-harvesting 2 complexes from Rhodopseudomonas palustris reveal the molecular origin of absorption tuning.
Proc.Natl.Acad.Sci.USA, 119, 2022
4K34
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BU of 4k34 by Molmil
Crystal structures of CusC review conformational changes accompanying folding and transmembrane channel formation
分子名称: Cation efflux system protein CusC
著者Su, C.-C.
登録日2013-04-10
公開日2013-10-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Crystal Structures of CusC Review Conformational Changes Accompanying Folding and Transmembrane Channel Formation.
J.Mol.Biol., 426, 2014
6KM3
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BU of 6km3 by Molmil
Human Carbonic Anhydrase II native 00 atm CO2
分子名称: Carbonic anhydrase 2, GLYCEROL, ZINC ION
著者Kim, C.U, Kim, J.K.
登録日2019-07-30
公開日2020-08-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Structural insights into the effect of active-site mutation on the catalytic mechanism of carbonic anhydrase.
Iucrj, 7, 2020
6ZGL
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BU of 6zgl by Molmil
Structure of DPS determined by movement-free cryoEM with zero dose extrapolation
分子名称: DNA protection during starvation protein
著者Naydenova, K, Russo, C.J.
登録日2020-06-19
公開日2020-10-21
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (1.9 Å)
主引用文献Cryo-EM with sub-1 angstrom specimen movement.
Science, 370, 2020
7ZH4
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BU of 7zh4 by Molmil
USP1 bound to ML323 and ubiquitin conjugated to FANCD2 (focused refinement)
分子名称: 5-methyl-2-(2-propan-2-ylphenyl)-~{N}-[[4-(1,2,3-triazol-1-yl)phenyl]methyl]pyrimidin-4-amine, Ubiquitin carboxyl-terminal hydrolase 1, Ubiquitin-60S ribosomal protein L40, ...
著者Rennie, M.L, Walden, H.
登録日2022-04-05
公開日2022-10-12
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.49 Å)
主引用文献Cryo-EM reveals a mechanism of USP1 inhibition through a cryptic binding site.
Sci Adv, 8, 2022
2CTI
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BU of 2cti by Molmil
DETERMINATION OF THE COMPLETE THREE-DIMENSIONAL STRUCTURE OF THE TRYPSIN INHIBITOR FROM SQUASH SEEDS IN AQUEOUS SOLUTION BY NUCLEAR MAGNETIC RESONANCE AND A COMBINATION OF DISTANCE GEOMETRY AND DYNAMICAL SIMULATED ANNEALING
分子名称: TRYPSIN INHIBITOR
著者Holak, T.A, Gondol, D, Otlewski, J, Wilusz, T.
登録日1990-08-28
公開日1992-01-15
最終更新日2024-10-30
実験手法SOLUTION NMR
主引用文献Determination of the complete three-dimensional structure of the trypsin inhibitor from squash seeds in aqueous solution by nuclear magnetic resonance and a combination of distance geometry and dynamical simulated annealing.
J.Mol.Biol., 210, 1989
7ZUD
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BU of 7zud by Molmil
Crystal structure of HIV-1 capsid IP6-CPSF6 complex
分子名称: Capsid protein p24, Cleavage and polyadenylation specificity factor subunit 6, INOSITOL HEXAKISPHOSPHATE
著者Nicastro, G, Taylor, I.A.
登録日2022-05-12
公開日2022-07-27
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.93 Å)
主引用文献CP-MAS and Solution NMR Studies of Allosteric Communication in CA-assemblies of HIV-1.
J.Mol.Biol., 434, 2022
2CTM
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BU of 2ctm by Molmil
Solution structure of the 14th KH type I domain from human Vigilin
分子名称: Vigilin
著者Tomizawa, T, Kigawa, T, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-24
公開日2005-11-24
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the 14th KH type I domain from human Vigilin
To be Published
6KE2
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BU of 6ke2 by Molmil
ABloop reengineered Ferritin Nanocage
分子名称: CALCIUM ION, CHLORIDE ION, FE (III) ION, ...
著者Wang, W.M, Wang, H.F.
登録日2019-07-03
公開日2019-10-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.798 Å)
主引用文献AB loop engineered ferritin nanocages for drug loading under benign experimental conditions.
Chem.Commun.(Camb.), 55, 2019
3CRK
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BU of 3crk by Molmil
Crystal structure of the PDHK2-L2 complex.
分子名称: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial, POTASSIUM ION, ...
著者Green, T.J, Popov, K.M, Luo, M, Grigorian, A, Klyuyeva, A, Tuganova, A.
登録日2008-04-07
公開日2008-04-29
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and functional insights into the molecular mechanisms responsible for the regulation of pyruvate dehydrogenase kinase 2.
J.Biol.Chem., 283, 2008
7ZGV
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BU of 7zgv by Molmil
Serratia NucC bound to cA3
分子名称: ACETATE ION, CALCIUM ION, RNA (5'-R(P*AP*AP*A)-3'), ...
著者Garcia-Doval, C, Mayo-Munoz, D, Smith, L.M, Fineran, P.C.
登録日2022-04-04
公開日2022-10-26
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Type III CRISPR-Cas provides resistance against nucleus-forming jumbo phages via abortive infection.
Mol.Cell, 82, 2022
5ZND
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BU of 5znd by Molmil
8-mer nanotube derived from 24-mer rHuHF nanocage
分子名称: Ferritin heavy chain
著者Wang, W.M, Wang, L.L, Zang, J.C, Chen, H, Zhao, G.H, Wang, H.F.
登録日2018-04-09
公開日2018-11-07
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Selective Elimination of the Key Subunit Interfaces Facilitates Conversion of Native 24-mer Protein Nanocage into 8-mer Nanorings.
J. Am. Chem. Soc., 140, 2018
4G0C
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BU of 4g0c by Molmil
Neutron structure of acetazolamide-bound human carbonic anhydrase II reveal molecular details of drug binding.
分子名称: 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, Carbonic anhydrase 2, ZINC ION
著者Fisher, S.Z, McKenna, R, Aggarwal, M.
登録日2012-07-09
公開日2012-09-19
最終更新日2023-09-13
実験手法NEUTRON DIFFRACTION (2 Å)
主引用文献Neutron diffraction of acetazolamide-bound human carbonic anhydrase II reveals atomic details of drug binding.
J.Am.Chem.Soc., 134, 2012
7ZO1
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BU of 7zo1 by Molmil
SpCas9 bound to CD34 off-target9 DNA substrate
分子名称: CD34 off-target9 DNA non-target strand, CD34 off-target9 DNA target strand, CD34 sgRNA, ...
著者Pacesa, M, Jinek, M.
登録日2022-04-23
公開日2022-10-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7LJC
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Allosteric modulator LY3154207 binding to SKF-81297-bound dopamine receptor 1 in complex with miniGs protein
分子名称: (1R)-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol, 2-[2,6-bis(chloranyl)phenyl]-1-[(1S,3R)-3-(hydroxymethyl)-1-methyl-5-(3-methyl-3-oxidanyl-butyl)-3,4-dihydro-1H-isoquinolin-2-yl]ethanone, CHOLESTEROL, ...
著者Zhuang, Y, Krumm, B, Zhang, H, Zhou, X.E, Wang, Y, Guo, J, Huang, X.-P, Liu, Y, Wang, L, Cheng, X, Jiang, Y, Jiang, H, Melcher, K, Zhang, C, Yi, W, Roth, B.L, Zhang, Y, Xu, H.E.
登録日2021-01-28
公開日2021-03-03
最終更新日2021-05-12
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor.
Cell Res., 31, 2021
7ZH3
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USP1 bound to ubiquitin conjugated to FANCD2 (focused refinement)
分子名称: Ubiquitin carboxyl-terminal hydrolase 1, Ubiquitin-60S ribosomal protein L40, ZINC ION
著者Rennie, M.L, Walden, H.
登録日2022-04-05
公開日2022-10-12
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Cryo-EM reveals a mechanism of USP1 inhibition through a cryptic binding site.
Sci Adv, 8, 2022

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