PDB: 243083 件ウェブページステータス検索Chemie searchBIRD

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6IX7	The structure of LepI C52A in complex with SAH and substrate analogue 分子名称: 1,2-ETHANEDIOL, 4-hydroxy-3-[(2S,6E,8E)-2-methyldeca-6,8-dienoyl]-5-phenylpyridin-2(1H)-one, CHLORIDE ION, ... 著者 Cai, Y, Ohashi, M, Hai, Y, Tang, Y, Zhou, J. 登録日 2018-12-09 公開日 2019-07-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.835 Å) 主引用文献 Structural basis for stereoselective dehydration and hydrogen-bonding catalysis by the SAM-dependent pericyclase LepI. Nat.Chem., 11, 2019
4W9K	pVHL:EloB:EloC in complex with (2S,4R)-1-((S)-2-((S)-2-acetamido-3-phenylpropanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (ligand 14) 分子名称: N-acetyl-L-phenylalanyl-3-methyl-L-valyl-(4R)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide, Transcription elongation factor B polypeptide 1, Transcription elongation factor B polypeptide 2, ... 著者 Gadd, M.S, Galdeano, C, van Molle, I, Ciulli, A. 登録日 2014-08-27 公開日 2014-09-10 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure-Guided Design and Optimization of Small Molecules Targeting the Protein-Protein Interaction between the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase and the Hypoxia Inducible Factor (HIF) Alpha Subunit with in Vitro Nanomolar Affinities. J.Med.Chem., 57, 2014
4UXU	Crystal Structure of the Extracellular Domain of the Human Alpha9 Nicotinic Acetylcholine Receptor In Complex with Methyllycaconitine 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Zouridakis, M, Giastas, P, Zarkadas, E, Tzartos, S.J. 登録日 2014-08-27 公開日 2014-10-01 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Crystal Structures of Free and Antagonist-Bound States of Human Alpha9 Nicotinic Receptor Extracellular Domain Nat.Struct.Mol.Biol., 21, 2014
6JO2	Ferredoxin I from Thermosynechococcus elongatus 分子名称: BENZAMIDINE, FE2/S2 (INORGANIC) CLUSTER, Ferredoxin-1, ... 著者 Motomura, T. 登録日 2019-03-19 公開日 2019-09-18 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 An alternative plant-like cyanobacterial ferredoxin with unprecedented structural and functional properties. Biochim Biophys Acta Bioenerg, 1860, 2019
4V5O	CRYSTAL STRUCTURE OF THE EUKARYOTIC 40S RIBOSOMAL SUBUNIT IN COMPLEX WITH INITIATION FACTOR 1. 分子名称: 18S RRNA, 40S RIBOSOMAL PROTEIN S12, 40S RIBOSOMAL PROTEIN S3A, ... 著者 Rabl, J, Leibundgut, M, Ataide, S.F, Haag, A, Ban, N. 登録日 2010-11-26 公開日 2014-07-09 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (3.93 Å) 主引用文献 Crystal Structure of the Eukaryotic 40S Ribosomal Subunit in Complex with Initiation Factor 1. Science, 331, 2011
6JJ1	Crystal structure of peptidyl-tRNA hydrolase from Acinetobacter baumannii at 0.97 A resolution with disordered five N-terminal residues 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Peptidyl-tRNA hydrolase 著者 Iqbal, N, Sharma, P, Chaudhary, A, Sharma, S, Singh, T.P. 登録日 2019-02-24 公開日 2019-03-13 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (0.97 Å) 主引用文献 Crystal structure of peptidyl-tRNA hydrolase from Acinetobacter baumannii at 0.97 A resolution with disordered five N-terminal residues To Be Published
6JOJ	Crystal structure of PDGFRA T674I in complex with crenolanib by soaking 分子名称: 1-(2-{5-[(3-Methyloxetan-3-yl)methoxy]-1H-benzimidazol-1-yl}quinolin-8-yl)piperidin-4-amine, CHLORIDE ION, Platelet-derived growth factor receptor alpha, ... 著者 Liang, L, Yan, X.E, Yun, C.H. 登録日 2019-03-22 公開日 2020-03-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of PDGFRA in complex with crenolanib by soaking To Be Published
6JOO	Crystal structure of Corynebacterium diphtheriae Cas9 in complex with sgRNA and target DNA 分子名称: 1,2-ETHANEDIOL, CRISPR-associated protein,CRISPR-associated endonuclease Cas9, Guide RNA, ... 著者 Hirano, S, Ishitani, R, Nishimasu, H, Nureki, O. 登録日 2019-03-22 公開日 2019-04-17 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis for the promiscuous PAM recognition by Corynebacterium diphtheriae Cas9. Nat Commun, 10, 2019
6IBX	Human PFKFB3 in complex with a N-Aryl 6-Aminoquinoxaline inhibitor 5 分子名称: 3-[[8-(1-methylindol-6-yl)quinoxalin-6-yl]amino]-~{N}-[(3~{S})-1-methylpiperidin-3-yl]pyridine-4-carboxamide, 6-O-phosphono-beta-D-fructofuranose, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3, ... 著者 Banaszak, K, Pawlik, H, Bialas, A, Fabritius, C.H, Nowak, M. 登録日 2018-12-01 公開日 2019-01-23 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Synthesis of amide and sulfonamide substituted N-aryl 6-aminoquinoxalines as PFKFB3 inhibitors with improved physicochemical properties. Bioorg. Med. Chem. Lett., 29, 2019
8XNO	Respiratory complex Peripheral Arm of CI, close form A, focus-refined map of type IA, Wild type mouse under Cold Acclimation 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... 著者 Shin, Y.-C, Liao, M. 登録日 2023-12-30 公開日 2024-10-30 最終更新日 2024-12-04 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural basis of respiratory complex adaptation to cold temperatures. Cell, 187, 2024
8XNV	Respiratory complex Peripheral Arm of CI, close form A, focus-refined map of type II, Wild type mouse under Cold Acclimation 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... 著者 Shin, Y.-C, Liao, M. 登録日 2023-12-30 公開日 2024-10-30 最終更新日 2024-12-04 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural basis of respiratory complex adaptation to cold temperatures. Cell, 187, 2024
8XNQ	Respiratory complex Peripheral Arm of CI, open form A, focus-refined map of type IA, Wild type mouse under Cold Acclimation 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... 著者 Shin, Y.-C, Liao, M. 登録日 2023-12-30 公開日 2024-10-30 最終更新日 2024-12-04 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural basis of respiratory complex adaptation to cold temperatures. Cell, 187, 2024
4TVH	HIV Protease (PR) dimer in closed form with TL-3 in active site and fragment AK-2097 in the outside/top of flap 分子名称: 3-(morpholin-4-ylmethyl)-1H-indole-6-carboxylic acid, BETA-MERCAPTOETHANOL, Protease, ... 著者 Tiefenbrunn, T, Kislukhin, A, Finn, M.G, Stout, C.D. 登録日 2014-06-26 公開日 2014-09-17 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.195 Å) 主引用文献 Distinguishing Binders from False Positives by Free Energy Calculations: Fragment Screening Against the Flap Site of HIV Protease. J.Phys.Chem.B, 119, 2015
6IHE	Crystal structure of Malate dehydrogenase from Metallosphaera sedula 分子名称: 1,2-ETHANEDIOL, D-MALATE, DI(HYDROXYETHYL)ETHER, ... 著者 Lee, D, Kim, K.J. 登録日 2018-09-29 公開日 2019-02-06 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure and biochemical characterization of malate dehydrogenase from Metallosphaera sedula Biochem. Biophys. Res. Commun., 509, 2019
4U63	Crystal structure of a bacterial class III photolyase from Agrobacterium tumefaciens at 1.67A resolution 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5,10-METHENYL-6,7,8-TRIHYDROFOLIC ACID, DNA photolyase, ... 著者 Scheerer, P, Zhang, F, Kalms, J, von Stetten, D, Krauss, N, Oberpichler, I, Lamparter, T. 登録日 2014-07-26 公開日 2015-03-25 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 The Class III Cyclobutane Pyrimidine Dimer Photolyase Structure Reveals a New Antenna Chromophore Binding Site and Alternative Photoreduction Pathways. J.Biol.Chem., 290, 2015
4UE7	Thrombin in complex with 1-amidinopiperidine 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... 著者 Ruehmann, E, Heine, A, Klebe, G. 登録日 2014-12-16 公開日 2015-08-26 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.129 Å) 主引用文献 Fragments Can Bind Either More Enthalpy or Entropy-Driven: Crystal Structures and Residual Hydration Pattern Suggest Why. J.Med.Chem., 58, 2015
6ITM	Crystal structure of FXR in complex with agonist XJ034 分子名称: 1-adamantyl-[4-(5-chloranyl-2-methyl-phenyl)piperazin-1-yl]methanone, Bile acid receptor, HD3 Peptide from Nuclear receptor coactivator 1 著者 Zhang, H, Wang, Z. 登録日 2018-11-23 公開日 2019-11-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Pose Filter-Based Ensemble Learning Enables Discovery of Orally Active, Nonsteroidal Farnesoid X Receptor Agonists. J.Chem.Inf.Model., 60, 2020
4UET	Diversity in the structures and ligand binding sites among the fatty acid and retinol binding proteins of nematodes revealed by Na-FAR-1 from Necator americanus 分子名称: NEMATODE FATTY ACID RETINOID BINDING PROTEIN 著者 Rey-Burusco, M.F, Ibanez Shimabukuro, M, Griffiths, K, Cooper, A, Kennedy, M.W, Corsico, B, Smith, B.O, Griffiths, K. 登録日 2014-12-18 公開日 2015-09-16 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Diversity in the Structures and Ligand Binding Sites of Nematode Fatty Acid and Retinol Binding Proteins Revealed by Na-Far-1 from Necator Americanus. Biochem.J., 471, 2015
4U5P	Crystal structure of native RhCC (YP_702633.1) from Rhodococcus jostii RHA1 at 1.78 Angstrom 分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, MAGNESIUM ION, ... 著者 Poddar, H, Rozeboom, H.J, Thunnissen, A.M.W.H. 登録日 2014-07-25 公開日 2015-02-25 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.782 Å) 主引用文献 Functional and structural characterization of an unusual cofactor-independent oxygenase. Biochemistry, 54, 2015
4U91	GephE in complex with Para-Phenyl crosslinked Glycine receptor beta subunit derived dimeric peptide 分子名称: 1,1'-benzene-1,4-diylbis(1H-pyrrole-2,5-dione), 1,2-ETHANEDIOL, ACETATE ION, ... 著者 Kasaragod, V.B, Maric, H.M, Schindelin, H. 登録日 2014-08-05 公開日 2014-12-10 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Design and Synthesis of High-Affinity Dimeric Inhibitors Targeting the Interactions between Gephyrin and Inhibitory Neurotransmitter Receptors. Angew.Chem.Int.Ed.Engl., 54, 2015
4UCT	Fragment bound to H.influenza NAD dependent DNA ligase 分子名称: 1-(2,4-dimethylbenzyl)-6-oxo-1,6-dihydropyridine-3-carboxamide, 2-amino-6-methyl-5-(propan-2-yloxy)-3H-[1,2,4]triazolo[1,5-a]pyrimidin-8-ium, DNA LIGASE 著者 Hale, M, Brassington, C, Carcanague, D, Embrey, K, Eyermann, C.J, Giacobbe, R.A, Gingipali, L, Gowravaram, M, Harang, J, Howard, T, Ioannidis, G, Jahic, H, Kutschke, A, Laganas, V.A, Loch, J, Miller, M.D, Murphy-Benenato, K.E, Oguto, H, Otterbein, L, Patel, S.J, Shapiro, A.B, Boriack-Sjodin, P.A. 登録日 2014-12-04 公開日 2015-10-14 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 From Fragments to Leads: Novel Bacterial Nad+-Dependent DNA Ligase Inhibitors Tetrahedron Lett., 56, 2015
6IX5	The structure of LepI complex with SAM and its substrate analogue 分子名称: 1,2-ETHANEDIOL, 4-hydroxy-3-[(2S,6E,8E)-2-methyldeca-6,8-dienoyl]-5-phenylpyridin-2(1H)-one, CHLORIDE ION, ... 著者 Cai, Y, Ohashi, M, Hai, Y, Tang, Y, Zhou, J. 登録日 2018-12-09 公開日 2019-07-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis for stereoselective dehydration and hydrogen-bonding catalysis by the SAM-dependent pericyclase LepI. Nat.Chem., 11, 2019
6VFR	Crystal structure of human protocadherin 18 EC1-EC4 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Harrison, O.J, Brasch, J, Shapiro, L. 登録日 2020-01-06 公開日 2020-03-11 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Family-wide Structural and Biophysical Analysis of Binding Interactions among Non-clustered delta-Protocadherins. Cell Rep, 30, 2020
7VT7	Crystal structure of CBM deleted MtGlu5 in complex with CBI 分子名称: Endoglucanase H, GLYCEROL, TRYPTOPHAN, ... 著者 Ye, T.J, Ko, P.T, Huang, K.F, Wu, S.H. 登録日 2021-10-28 公開日 2022-09-07 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Synergic action of an inserted carbohydrate-binding module in a glycoside hydrolase family 5 endoglucanase. Acta Crystallogr D Struct Biol, 78, 2022
7W59	The cryo-EM structure of human pre-C*-I complex 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... 著者 Zhan, X, Lu, Y, Shi, Y. 登録日 2021-11-29 公開日 2022-06-22 最終更新日 2025-06-18 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022

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