PDB: 30867 件ウェブページステータス検索Chemie searchBIRD

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8S9R	SAL2, Staphylococcus aureus lipase 2 (geh, lip2), apo form 分子名称: CALCIUM ION, Lipase 2, PHOSPHATE ION, ... 著者 Fellner, M. 登録日 2023-03-30 公開日 2024-04-10 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 SAL2, Staphylococcus aureus lipase 2 (geh, lip2), apo form To Be Published
6Z10	Crystal structure of a humanized (K18E, K269N) rat succinate receptor SUCNR1 (GPR91) in complex with a nanobody and antagonist 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-[2-[[3-[4-chloranyl-2-fluoranyl-5-[(3~{R})-piperidin-3-yl]oxy-phenyl]-2-fluoranyl-phenyl]carbonylamino]-5-fluoranyl-phenyl]ethanoic acid, CHLORIDE ION, ... 著者 Haffke, M, Villard, F. 登録日 2020-05-11 公開日 2020-09-16 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.269 Å) 主引用文献 Discovery and Optimization of Novel SUCNR1 Inhibitors: Design of Zwitterionic Derivatives with a Salt Bridge for the Improvement of Oral Exposure. J.Med.Chem., 63, 2020
6ZLJ	Crystal Structure of UDP-Glucuronic acid 4-epimerase Y149F mutant from Bacillus cereus in complex with UDP-4-DEOXY-4-FLUORO-Glucuronic acid and NAD 分子名称: (2~{R},3~{S},4~{R},5~{R},6~{R})-6-[[[(2~{R},3~{S},4~{R},5~{R})-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidany l)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3-fluoranyl-4,5-bis(oxidanyl)oxane-2-carboxylic acid, Epimerase domain-containing protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Iacovino, L.G, Mattevi, A. 登録日 2020-06-30 公開日 2020-07-29 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystallographic snapshots of UDP-glucuronic acid 4-epimerase ligand binding, rotation, and reduction. J.Biol.Chem., 295, 2020
8S9J	FphA, Staphylococcus aureus fluorophosphonate-binding serine hydrolases A, apo form 分子名称: Fluorophosphonate-binding serine hydrolase A, SULFATE ION 著者 Fellner, M. 登録日 2023-03-28 公開日 2024-04-10 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 FphA, Staphylococcus aureus fluorophosphonate-binding serine hydrolases A, apo form To Be Published
6AYQ	Crystal structure of Campylobacter jejuni 5'-methylthioadenosine/S-adenosyl homocysteine nucleosidase (MTAN) complexed with methylthio-DADMe-Immucillin-A 分子名称: (3R,4S)-1-[(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)METHYL]-4-[(METHYLSULFANYL)METHYL]PYRROLIDIN-3-OL, 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, GLYCEROL 著者 Cameron, S.A, Harijan, R.K, Ducati, R.G, Bonanno, J.B, Almo, S.C, Schramm, V.L. 登録日 2017-09-08 公開日 2018-09-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Transition-State Analogues of Campylobacter jejuni 5'-Methylthioadenosine Nucleosidase. ACS Chem. Biol., 13, 2018
6Z17	PqsR (MvfR) in complex with antagonist 6 分子名称: 6-chloranyl-3-[(2-propan-2-yl-2,3-dihydro-1,3-thiazol-4-yl)methyl]quinazolin-4-one, Transcriptional regulator MvfR 著者 Richardson, W.K, Emsley, J. 登録日 2020-05-12 公開日 2020-09-16 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Novel quinazolinone inhibitors of the Pseudomonas aeruginosa quorum sensing transcriptional regulator PqsR. Eur.J.Med.Chem., 208, 2020
6YSH	Lamin A 1-70 coil1A dimer stabilized by C-terminal capping 分子名称: Prelamin-A/C,Microtubule-associated protein RP/EB family member 1 著者 Stalmans, G, Lilina, A.V, Strelkov, S.V. 登録日 2020-04-22 公開日 2020-09-02 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.83 Å) 主引用文献 Addressing the Molecular Mechanism of Longitudinal Lamin Assembly Using Chimeric Fusions. Cells, 9, 2020
7QR6	Stilbene dioxygenase (NOV1) from Novosphingobium aromaticivorans: Ser283Phe mutant 分子名称: Dioxygenase, FE (III) ION, OXYGEN MOLECULE 著者 Alvigini, L, Mattevi, A. 登録日 2022-01-10 公開日 2022-08-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Rationally Guided Improvement of NOV1 Dioxygenase for the Conversion of Lignin-Derived Isoeugenol to Vanillin. Biochemistry, 62, 2023
6Q7B	Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with the NVP-BHG712 derivative ATDL09 分子名称: 3-[[4-imidazol-1-yl-6-[(3~{S})-3-oxidanylpyrrolidin-1-yl]-1,3,5-triazin-2-yl]amino]-4-methyl-~{N}-[3-(trifluoromethyl)phenyl]benzamide, Ephrin type-A receptor 2 著者 Kudlinzki, D, Troester, A, Witt, K, Linhard, V.L, Gande, S.L, Saxena, K, Schwalbe, H. 登録日 2018-12-13 公開日 2020-01-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.009 Å) 主引用文献 Effects of NVP-BHG712 chemical modifications on EPHA2 binding and affinity To Be Published
7LQM	Glucosamie-6-phosphate Deaminase from Pasturella multocida 分子名称: 1,2-ETHANEDIOL, Glucosamine-6-phosphate deaminase 著者 Subramanian, R, Srinivasachari, S. 登録日 2021-02-14 公開日 2022-01-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 A dimer between monomers and hexamers-Oligomeric variations in glucosamine-6-phosphate deaminase family. Plos One, 18, 2023
6QCG	PCNA complex with Cdt1 N-terminal PIP-box peptide 分子名称: DNA replication factor Cdt1, Proliferating cell nuclear antigen 著者 Perrakis, A, von Castelmur, E. 登録日 2018-12-28 公開日 2019-01-23 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Direct binding of Cdt2 to PCNA is important for targeting the CRL4Cdt2E3 ligase activity to Cdt1. Life Sci Alliance, 1, 2018
6HG7	Crystal structure of a collagen II fragment containing the binding site of PEDF and COMP, (POG)4-LKG HRG FTG LQG-POG(4) 分子名称: Collagen alpha-1(II) chain, SULFATE ION 著者 Gebauer, J.M, Koehler, A, Dietmar, H, Gompert, M, Neundorf, I, Zaucke, F, Koch, M, Baumann, U. 登録日 2018-08-22 公開日 2018-12-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 COMP and TSP-4 interact specifically with the novel GXKGHR motif only found in fibrillar collagens. Sci Rep, 8, 2018
5HGO	Hexameric HIV-1 CA R18G mutant 分子名称: Capsid protein P24 著者 Jacques, D.A, James, L.C. 登録日 2016-01-08 公開日 2016-08-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis. Nature, 536, 2016
6Q7I	GH3 exo-beta-xylosidase (XlnD) 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Davies, G.J, Rowland, R.J, Wu, L, Moroz, O, Blagova, E. 登録日 2018-12-13 公開日 2019-06-05 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Dynamic and Functional Profiling of Xylan-Degrading Enzymes inAspergillusSecretomes Using Activity-Based Probes. Acs Cent.Sci., 5, 2019
7LB3	Crystal structure of the second bromodomain (BD2) of human TAF1 bound to ZS1-580 分子名称: 1,2-ETHANEDIOL, 4-{4-[(3R)-3-methylmorpholin-4-yl]-6-[1-(S-methylsulfonimidoyl)cyclopropyl]pyrimidin-2-yl}-1H-indazole, Transcription initiation factor TFIID subunit 1 著者 Karim, M.R, Schonbrunn, E. 登録日 2021-01-07 公開日 2022-01-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of the second bromodomain (BD2) of human TAF1 bound to ZS1-580 To Be Published
5UQE	Multidomain structure of human kidney-type glutaminase(KGA/GLS) 分子名称: Glutaminase kidney isoform, mitochondrial, N,N'-[sulfanediylbis(ethane-2,1-diyl-1,3,4-thiadiazole-5,2-diyl)]bis(2-phenylacetamide) 著者 Pasquali, C.C, Dias, S.M.G, Ambrosio, A.L.B. 登録日 2017-02-08 公開日 2017-05-24 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats. J. Biol. Chem., 292, 2017
5HME	Crystal structure of Triazine Hydrolase variant (P214T/Y215H) 分子名称: Triazine hydrolase, ZINC ION 著者 Sugrue, E, Carr, P.D, Jackson, C.J. 登録日 2016-01-16 公開日 2016-11-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.151 Å) 主引用文献 Active Site Desolvation and Thermostability Trade-Offs in the Evolution of Catalytically Diverse Triazine Hydrolases. Biochemistry, 55, 2016
7LC7	Crystal structure of epoxyqueuosine reductase QueH in complex with GMP from Thermotoga maritima 分子名称: CHLORIDE ION, Epoxyqueuosine reductase QueH, FE (III) ION, ... 著者 Li, Q, Bruner, S.D. 登録日 2021-01-09 公開日 2022-01-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 The epoxyqueuosine reductase QueH in the biosynthesis of tRNA queuosine is a unique metalloenzyme To Be Published
6Q8B	Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with 5'-O-(N-(L-Leucyl)-Sulfamoyl)N3-methyluridine 分子名称: 1,2-ETHANEDIOL, Leucine--tRNA ligase, MAGNESIUM ION, ... 著者 Pang, L, De Graef, S, Strelkov, S.V, Weeks, S.D. 登録日 2018-12-14 公開日 2019-04-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Comparative analysis of pyrimidine substituted aminoacyl-sulfamoyl nucleosides as potential inhibitors targeting class I aminoacyl-tRNA synthetases. Eur.J.Med.Chem., 173, 2019
6AXG	Structure of RasGRP4 in complex with HRas 分子名称: GTPase HRas, RAS guanyl-releasing protein 4 著者 Kondo, Y, Iwig, J.S, Kuriyan, J. 登録日 2017-09-06 公開日 2017-10-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.302 Å) 主引用文献 A histidine pH sensor regulates activation of the Ras-specific guanine nucleotide exchange factor RasGRP1. Elife, 6, 2017
7LXE	ENAH EVH1 domain bound to peptide from ABI1 分子名称: Protein enabled homolog,Abl interactor 1 著者 Keating, A.E, Grant, R.A, Hwang, T.H. 登録日 2021-03-03 公開日 2022-01-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Native proline-rich motifs exploit sequence context to target actin-remodeling Ena/VASP protein ENAH. Elife, 11, 2022
8ROM	Crystal structure of human FAD synthase PAPS domain in complex with FAD 分子名称: FAD synthase, FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHATE ION 著者 Leo, G, Capaldi, S. 登録日 2024-01-11 公開日 2024-04-10 最終更新日 2024-07-24 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Structural insights into the bifunctional enzyme human FAD synthase. Structure, 32, 2024
6Q8N	GH10 endo-xylanase in complex with xylobiose epoxide inhibitor 分子名称: (1~{R},2~{S},4~{S},5~{R})-cyclohexane-1,2,3,4,5-pentol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Davies, G.J, Rowland, R.J, Wu, L, Moroz, O, Blagova, E. 登録日 2018-12-15 公開日 2019-06-05 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Dynamic and Functional Profiling of Xylan-Degrading Enzymes inAspergillusSecretomes Using Activity-Based Probes. Acs Cent.Sci., 5, 2019
6HHE	Crystal structure of the medfly Odorant Binding Protein CcapOBP22/CcapOBP69a 分子名称: 2-(2-METHOXYETHOXY)ETHANOL, Odorant binding protein OBP69a, SULFATE ION 著者 Falchetto, M, Ciossani, G, Nenci, S, Mattevi, A, Gasperi, G, Forneris, F. 登録日 2018-08-28 公開日 2018-12-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.516 Å) 主引用文献 Structural and biochemical evaluation of Ceratitis capitata odorant-binding protein 22 affinity for odorants involved in intersex communication. Insect Mol.Biol., 28, 2019
7LL5	High-resolution crystal structure of human JAK2 kinase domain (JH1) bound to PN5-150. 分子名称: 1,2-ETHANEDIOL, Tyrosine-protein kinase JAK2, {1-(ethylsulfonyl)-3-[4-(2-{[4-(1-methylpiperidin-4-yl)phenyl]amino}-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]azetidin-3-yl}acetonitrile 著者 Karim, M.R, Schonbrunn, E. 登録日 2021-02-03 公開日 2022-01-12 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 High-resolution crystal structure of human JAK2 kinase domain (JH1) bound to PN5-150. To Be Published

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