7LB3

Crystal structure of the second bromodomain (BD2) of human TAF1 bound to ZS1-580

Summary for 7LB3

• Entry DOI: 10.2210/pdb7lb3/pdb
• Descriptor: Transcription initiation factor TFIID subunit 1, 4-{4-[(3R)-3-methylmorpholin-4-yl]-6-[1-(S-methylsulfonimidoyl)cyclopropyl]pyrimidin-2-yl}-1H-indazole, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: bromodomain, taf1, non-bet, bet, kinase inhibitor, atr, dual brd-kinase, transferase, gene regulation
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 16357.39

Authors

Karim, M.R.,Schonbrunn, E. (deposition date: 2021-01-07, release date: 2022-01-12, Last modification date: 2023-10-18)

• Primary citation: Karim, M.R.,Schonbrunn, E.; Crystal structure of the second bromodomain (BD2) of human TAF1 bound to ZS1-580; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)