7LB3
Crystal structure of the second bromodomain (BD2) of human TAF1 bound to ZS1-580
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Transcription initiation factor TFIID subunit 1 | polymer | 137 | 15882.8 | 1 | UniProt (P21675) Pfam (PF00439) In PDB | Homo sapiens (Human) | Cell cycle gene 1 protein,TBP-associated factor 250 kDa,p250,Transcription initiation factor TFIID 250 kDa subunit,TAFII250 |
| 2 | A | 4-{4-[(3R)-3-methylmorpholin-4-yl]-6-[1-(S-methylsulfonimidoyl)cyclopropyl]pyrimidin-2-yl}-1H-indazole | non-polymer | 412.5 | 1 | Chemie (XXS) | |||
| 3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | water | water | 18.0 | 154 | Chemie (HOH) |
Sequence modifications
A: 1501 - 1635 (UniProt: P21675)
| PDB | External Database | Details |
|---|---|---|
| Ser 1499 | - | expression tag |
| Met 1500 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15882.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 474.6 | |
| All* | Total formula weight | 16357.4 |
