7QY5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qy5 by Molmil](/molmil-images/mine/7qy5) | |
7LUI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7lui by Molmil](/molmil-images/mine/7lui) | |
6YTB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ytb by Molmil](/molmil-images/mine/6ytb) | GLYCOSYLATED KNOB/DUMMY-HOLE/DUMMY FC FRAGMENT | 分子名称: | Immunoglobulin gamma-1 heavy chain, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Kuglstatter, A, Leibrock, L, Benz, J. | 登録日 | 2020-04-24 | 公開日 | 2020-10-14 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Format chain exchange (FORCE) for high-throughput generation of bispecific antibodies in combinatorial binder-format matrices. Nat Commun, 11, 2020
|
|
8AVT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8avt by Molmil](/molmil-images/mine/8avt) | Racemic protein crystal structure of aureocin A53 from Staphylococcus aureus in the presence of glycerol 3-phosphate | 分子名称: | 1,2-ETHANEDIOL, Bacteriocin aureocin A53, D-Aureocin A53, ... | 著者 | Lander, A.J, Baumann, P, Rizkallah, P, Jin, Y, Luk, L.Y.P. | 登録日 | 2022-08-26 | 公開日 | 2023-07-26 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Roles of inter- and intramolecular tryptophan interactions in membrane-active proteins revealed by racemic protein crystallography. Commun Chem, 6, 2023
|
|
6I0K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6i0k by Molmil](/molmil-images/mine/6i0k) | Structure of quinolinate synthase in complex with 4-mercaptophthalic acid | 分子名称: | 4-mercaptoidenecyclohexa-2,5-diene-1,2-dicarboxylic acid, CHLORIDE ION, IRON/SULFUR CLUSTER, ... | 著者 | Volbeda, A, Fontecilla-Camps, J.C. | 登録日 | 2018-10-26 | 公開日 | 2019-03-20 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Design of specific inhibitors of quinolinate synthase based on [4Fe-4S] cluster coordination. Chem.Commun.(Camb.), 55, 2019
|
|
6QFV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6qfv by Molmil](/molmil-images/mine/6qfv) | Human carbonic anhydrase II with bound IrCp* complex (cofactor 8) to generate an artificial transfer hydrogenase (ATHase) | 分子名称: | 4-[2-(9-chloranyl-2',3',4',5',6'-pentamethyl-7-oxidanylidene-spiro[1$l^{4},8-diaza-9$l^{8}-iridabicyclo[4.3.0]nona-1(6),2,4-triene-9,1'-1$l^{8}-iridapentacyclo[2.2.0.0^{1,3}.0^{1,5}.0^{2,6}]hexane]-8-yl)ethyl]benzenesulfonamide, Carbonic anhydrase 2, SULFATE ION, ... | 著者 | Rebelein, J.G. | 登録日 | 2019-01-10 | 公開日 | 2019-04-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Chemical Optimization of Whole-Cell Transfer Hydrogenation Using Carbonic Anhydrase as Host Protein. Acs Catalysis, 9, 2019
|
|
7QF7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qf7 by Molmil](/molmil-images/mine/7qf7) | |
6G68
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6g68 by Molmil](/molmil-images/mine/6g68) | |
8SJ2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8sj2 by Molmil](/molmil-images/mine/8sj2) | |
6ARF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6arf by Molmil](/molmil-images/mine/6arf) | Aspergillus fumigatus Cytosolic Thiolase: Apo enzyme in complex with potassium ions | 分子名称: | Acetyl-CoA acetyltransferase, CHLORIDE ION, GLYCEROL, ... | 著者 | Marshall, A.C, Bond, C.S, Bruning, J.B. | 登録日 | 2017-08-22 | 公開日 | 2018-05-30 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.702 Å) | 主引用文献 | Structure of Aspergillus fumigatus Cytosolic Thiolase: Trapped Tetrahedral Reaction Intermediates and Activation by Monovalent Cations Acs Catalysis, 8(3), 2018
|
|
8AVU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8avu by Molmil](/molmil-images/mine/8avu) | Racemic protein crystal structure of aureocin A53 from Staphylococcus aureus in the dimeric state | 分子名称: | 1,2-ETHANEDIOL, Bacteriocin aureocin A53, D-Aureocin A53, ... | 著者 | Lander, A.J, Baumann, P, Rizkallah, P, Jin, Y, Luk, L.Y.P. | 登録日 | 2022-08-26 | 公開日 | 2023-07-26 | 実験手法 | X-RAY DIFFRACTION (0.89 Å) | 主引用文献 | Roles of inter- and intramolecular tryptophan interactions in membrane-active proteins revealed by racemic protein crystallography. Commun Chem, 6, 2023
|
|
7L8R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7l8r by Molmil](/molmil-images/mine/7l8r) | Crystal structure of human GPX4-U46C mutant K48A | 分子名称: | Isoform Cytoplasmic of Phospholipid hydroperoxide glutathione peroxidase, THIOCYANATE ION | 著者 | Forouhar, F, Liu, H, Seibt, T, Saneto, R, Wigby, K, Friedman, J, Xia, X, Shchepinov, M.S, Ramesh, S, Conrad, M, Stockwell, B.R. | 登録日 | 2020-12-31 | 公開日 | 2021-12-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | Patient-derived variant of GPX4 reveals the structural basis for its catalytic activity and degradation mechanism Nat.Chem.Biol., 2021
|
|
8RP4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8rp4 by Molmil](/molmil-images/mine/8rp4) | Alpha-Methylacyl-CoA racemase from Mycobacterium tuberculosis (D156A mutant) | 分子名称: | 1,2-ETHANEDIOL, Alpha-methylacyl-CoA racemase, DI(HYDROXYETHYL)ETHER | 著者 | Mojanaga, O.O, Acharya, K.R, Lloyd, M.D. | 登録日 | 2024-01-12 | 公開日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | alpha-Methylacyl-CoA Racemase from Mycobacterium tuberculosis -Detailed Kinetic and Structural Characterization of the Active Site. Biomolecules, 14, 2024
|
|
8AVR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8avr by Molmil](/molmil-images/mine/8avr) | Racemic protein crystal structure of aureocin A53 from Staphylococcus aureus in the presence of sulfate | 分子名称: | 1,2-ETHANEDIOL, Bacteriocin aureocin A53, D-Aureocin A53, ... | 著者 | Lander, A.J, Baumann, P, Rizkallah, P, Jin, Y, Luk, L.Y.P. | 登録日 | 2022-08-26 | 公開日 | 2023-07-26 | 実験手法 | X-RAY DIFFRACTION (1.13 Å) | 主引用文献 | Roles of inter- and intramolecular tryptophan interactions in membrane-active proteins revealed by racemic protein crystallography. Commun Chem, 6, 2023
|
|
6HI0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6hi0 by Molmil](/molmil-images/mine/6hi0) | Klebsiella pneumoniae Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-Sulfamoyl)uridine | 分子名称: | 1,2-ETHANEDIOL, 5'-O-(N-(L-seryl)-Sulfamoyl)uridine, CALCIUM ION, ... | 著者 | Pang, L, De Graef, S, Weeks, S.D, Strelkov, S.V. | 登録日 | 2018-08-29 | 公開日 | 2019-12-18 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases. Acs Chem.Biol., 15, 2020
|
|
6G6H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6g6h by Molmil](/molmil-images/mine/6g6h) | |
6AR3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ar3 by Molmil](/molmil-images/mine/6ar3) | Structure of a Thermostable Group II Intron Reverse Transcriptase with Template-Primer and Its Functional and Evolutionary Implications (RT/Duplex (Se-Met)) | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA, GsI-IIC RT, ... | 著者 | Stamos, J.L, Lentzsch, A.M, Lambowitz, A.M. | 登録日 | 2017-08-21 | 公開日 | 2017-11-29 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.41 Å) | 主引用文献 | Structure of a Thermostable Group II Intron Reverse Transcriptase with Template-Primer and Its Functional and Evolutionary Implications. Mol. Cell, 68, 2017
|
|
6ZFA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zfa by Molmil](/molmil-images/mine/6zfa) | Structure of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with GlcIFG, alpha-1,2-mannobiose and hexatungstotellurate(VI) TEW | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE, 6-tungstotellurate(VI), ... | 著者 | Sobala, L.F, Fernandes, P.Z, Hakki, Z, Thompson, A.J, Howe, J.D, Hill, M, Zitzmann, N, Davies, S, Stamataki, Z, Butters, T.D, Alonzi, D.S, Williams, S.J, Davies, G.J. | 登録日 | 2020-06-16 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
5HF7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5hf7 by Molmil](/molmil-images/mine/5hf7) | TDG enzyme-substrate complex | 分子名称: | DNA (28-MER), G/T mismatch-specific thymine DNA glycosylase | 著者 | Pozharski, E, Malik, S.S, Drohat, A.C. | 登録日 | 2016-01-06 | 公開日 | 2016-09-28 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Structural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residues. Nucleic Acids Res., 44, 2016
|
|
6FT1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ft1 by Molmil](/molmil-images/mine/6ft1) | Crystal structure of oxidised Flavodoxin 1 from Bacillus cereus (1.4 A resolution) | 分子名称: | FLAVIN MONONUCLEOTIDE, Flavodoxin, SULFATE ION, ... | 著者 | Gudim, I, Lofstad, M, Hersleth, H.-P. | 登録日 | 2018-02-20 | 公開日 | 2018-07-11 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | High-resolution crystal structures reveal a mixture of conformers of the Gly61-Asp62 peptide bond in an oxidized flavodoxin from Bacillus cereus. Protein Sci., 27, 2018
|
|
8AVS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8avs by Molmil](/molmil-images/mine/8avs) | Racemic protein crystal structure of aureocin A53 from Staphylococcus aureus in the presence of citrate and acetate | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Bacteriocin aureocin A53, ... | 著者 | Lander, A.J, Baumann, P, Rizkallah, P, Jin, Y, Luk, L.Y.P. | 登録日 | 2022-08-26 | 公開日 | 2023-07-26 | 実験手法 | X-RAY DIFFRACTION (1.21 Å) | 主引用文献 | Roles of inter- and intramolecular tryptophan interactions in membrane-active proteins revealed by racemic protein crystallography. Commun Chem, 6, 2023
|
|
6ARG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6arg by Molmil](/molmil-images/mine/6arg) | Aspergillus fumigatus Cytosolic Thiolase: Apo enzyme in complex with rubidium ions | 分子名称: | Acetyl-CoA acetyltransferase, CHLORIDE ION, GLYCEROL, ... | 著者 | Marshall, A.C, Bond, C.S, Bruning, J.B. | 登録日 | 2017-08-22 | 公開日 | 2018-05-30 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.782 Å) | 主引用文献 | Structure of Aspergillus fumigatus Cytosolic Thiolase: Trapped Tetrahedral Reaction Intermediates and Activation by Monovalent Cations Acs Catalysis, 8(3), 2018
|
|
5UJ8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5uj8 by Molmil](/molmil-images/mine/5uj8) | Human Origin Recognition Complex subunits 2 and 3 | 分子名称: | Origin recognition complex subunit 2, Origin recognition complex subunit 3 | 著者 | Tocilj, A, On, K.F, Elkayam, E, Joshua-Tor, L. | 登録日 | 2017-01-17 | 公開日 | 2017-02-08 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (6 Å) | 主引用文献 | Structure of the active form of human Origin Recognition Complex and its ATPase motor module. Elife, 6, 2017
|
|
5H5Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5h5y by Molmil](/molmil-images/mine/5h5y) | |
5UK8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5uk8 by Molmil](/molmil-images/mine/5uk8) | The co-structure of (R)-4-(6-(1-(cyclopropylsulfonyl)cyclopropyl)-2-(1H-indol-4-yl)pyrimidin-4-yl)-3-methylmorpholine and a rationally designed PI3K-alpha mutant that mimics ATR | 分子名称: | (R)-4-(6-(1-(cyclopropylsulfonyl)cyclopropyl)-2-(1H-indol-4-yl)pyrimidin-4-yl)-3-methylmorpholine, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | 著者 | Knapp, M.S, Mamo, M, Elling, R.A. | 登録日 | 2017-01-20 | 公開日 | 2017-06-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Rationally Designed PI3K alpha Mutants to Mimic ATR and Their Use to Understand Binding Specificity of ATR Inhibitors. J. Mol. Biol., 429, 2017
|
|