7LUI

Crystal structure of Vibrio cholerae DsbA in complex with bile salt taurocholate

Summary for 7LUI

• Entry DOI: 10.2210/pdb7lui/pdb
• Descriptor: Thiol:disulfide interchange protein DsbA, GLYCEROL, TAUROCHOLIC ACID, ... (4 entities in total)
• Functional Keywords: inhibitor, complex, antibacterial, oxidoreductase
• Biological source: Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
• Total number of polymer chains: 1
• Total formula weight: 21103.16

Authors

Wang, G.,Heras, B. (deposition date: 2021-02-22, release date: 2021-12-29, Last modification date: 2023-10-18)

• Primary citation: Wang, G.,Mohanty, B.,Williams, M.L.,Doak, B.C.,Dhouib, R.,Totsika, M.,McMahon, R.M.,Sharma, G.,Zheng, D.,Bentley, M.R.,Ka-Yan Chin, Y.,Horne, J.,Chalmers, D.K.,Heras, B.,Scanlon, M.J.; Selective Binding of Small Molecules to Vibrio cholerae DsbA Offers a Starting Point for the Design of Novel Antibacterials.; Chemmedchem, 17:e202100673-e202100673, 2022; PubMed: 34978144; DOI: 10.1002/cmdc.202100673

Experimental method

X-RAY DIFFRACTION (1.74 Å)