PDB: 41522 件ウェブページステータス検索Chemie searchBIRD

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6XM0	Consensus structure of SARS-CoV-2 spike at pH 5.5 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein 著者 Zhou, T, Tsybovsky, Y, Olia, A, Kwong, P.D. 登録日 2020-06-29 公開日 2020-08-12 最終更新日 2021-12-15 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains. Cell Host Microbe, 28, 2020
1Y55	Crystal structure of the C122S mutant of E. Coli expressed avidin related protein 4 (AVR4)-biotin complex 分子名称: Avidin-related protein 4/5, BIOTIN, FORMIC ACID 著者 Eisenberg-Domovich, Y, Hytonen, V.P, Wilchek, M, Bayer, E.A, Kulomaa, M.S, Livnah, O. 登録日 2004-12-02 公開日 2005-05-24 最終更新日 2021-11-10 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 High-resolution crystal structure of an avidin-related protein: insight into high-affinity biotin binding and protein stability. Acta Crystallogr.,Sect.D, 61, 2005
1HD1	HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D0 (HNRNP D0 RBD1), NMR 分子名称: PROTEIN (HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D0) 著者 Nagata, T, Kurihara, Y, Matsuda, G, Saeki, J, Kohno, T, Yanagida, Y, Ishikawa, F, Uesugi, S, Katahira, M. 登録日 1999-05-18 公開日 2000-05-18 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Structure and interactions with RNA of the N-terminal UUAG-specific RNA-binding domain of hnRNP D0. J.Mol.Biol., 287, 1999
5L0H	Human metavinculin MVt cardiomyopathy-associated mutant R975W (residues 959-1134) in complex with PIP2 分子名称: DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, Vinculin, ... 著者 Chinthalapudi, K, Izard, T. 登録日 2016-07-27 公開日 2016-08-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization. Proc.Natl.Acad.Sci.USA, 113, 2016
6XHA	Crystal Structure of KRAS-G12V (GMPPNP-bound) in complex with RAS-binding domain (RBD) and cysteine-rich domain (CRD) of RAF1/CRAF 分子名称: CHLORIDE ION, GLYCEROL, Isoform 2B of GTPase KRas, ... 著者 Tran, T.H, Chan, A.H, Dharmaiah, S, Simanshu, D.K. 登録日 2020-06-18 公開日 2021-01-13 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.87 Å) 主引用文献 KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation. Nat Commun, 12, 2021
5NPO	Promiscuous Protein Self-Assembly as a Function of Protein Stability 分子名称: Beta-lactamase, Beta-lactamase TEM, MAGNESIUM ION 著者 Cohen-Khait, R, Dym, O, Hamer-Rogotner, S, Schreiber, G. 登録日 2017-04-18 公開日 2017-12-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Promiscuous Protein Binding as a Function of Protein Stability. Structure, 25, 2017
6XGV	Crystal Structure of KRAS-G13D (GMPPNP-bound) in complex with RAS-binding domain (RBD) and cysteine-rich domain (CRD) of RAF1/CRAF 分子名称: CHLORIDE ION, GLYCEROL, GTPase KRas, ... 著者 Tran, T.H, Chan, A.H, Dharmaiah, S, Simanshu, D.K. 登録日 2020-06-18 公開日 2021-01-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation. Nat Commun, 12, 2021
5KLG	Structure of CavAb(W195Y) in complex with Br-dihydropyridine derivative UK-59811 分子名称: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein, ... 著者 Tang, L, Gamal EL-Din, T.M, Swanson, T.M, Pryde, D.C, Scheuer, T, Zheng, N, Catterall, W.A. 登録日 2016-06-24 公開日 2016-08-31 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs. Nature, 537, 2016
6KEX	Crystal structure of reduced phosphoribulokinase from Arabidopsis thaliana 分子名称: Phosphoribulokinase 著者 Yu, A, Xie, Y, Li, M. 登録日 2019-07-05 公開日 2020-05-13 最終更新日 2020-05-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Photosynthetic Phosphoribulokinase Structures: Enzymatic Mechanisms and the Redox Regulation of the Calvin-Benson-Bassham Cycle. Plant Cell, 32, 2020
5NAO	NMR structure of TLR4 transmembrane domain (624-657) in DPC micelles 分子名称: Toll-like receptor 4 著者 Mineev, K.S, Goncharuk, S.A, Goncharuk, M.V, Arseniev, A.S. 登録日 2017-02-28 公開日 2018-03-21 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Spatial structure of TLR4 transmembrane domain in bicelles provides the insight into the receptor activation mechanism. Sci Rep, 7, 2017
6DQO	Crystal structure of SsuE FMN reductase Y118A mutant in FMN bound form. 分子名称: FLAVIN MONONUCLEOTIDE, FMN reductase (NADPH), GLYCEROL 著者 McFarlane, J.S, Ellis, H.R, Lamb, A.L. 登録日 2018-06-11 公開日 2019-01-09 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.705 Å) 主引用文献 Not as easy as pi : An insertional residue does not explain the pi-helix gain-of-function in two-component FMN reductases. Protein Sci., 28, 2019
2P24	I-Au/MBP125-135 分子名称: H-2 class II histocompatibility antigen, A-U alpha chain, A-U beta chain 著者 McBeth, C, Strong, R.K. 登録日 2007-03-06 公開日 2008-01-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 A new twist in TCR diversity revealed by a forbidden alphabeta TCR. J.Mol.Biol., 375, 2008
7M2M	NMR Structure of GCAP5 分子名称: Guanylate cyclase activator 1A, MAGNESIUM ION 著者 Ames, J.B, Cudia, D.L. 登録日 2021-03-17 公開日 2021-10-20 最終更新日 2021-11-03 実験手法 SOLUTION NMR 主引用文献 NMR and EPR-DEER Structure of a Dimeric Guanylate Cyclase Activator Protein-5 from Zebrafish Photoreceptors. Biochemistry, 60, 2021
7C9B	Crystal structure of dipeptidase-E from Xenopus laevis 分子名称: Alpha-aspartyl dipeptidase, CALCIUM ION, SODIUM ION 著者 Kumar, A, Singh, R, Makde, R.D. 登録日 2020-06-05 公開日 2021-06-09 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structure of aspartyl dipeptidase from Xenopus laevis revealed ligand binding induced loop ordering and catalytic triad assembly. Proteins, 90, 2022
5NAM	NMR structure of TLR4 transmembrane domain (624-670) in DMPG/DHPC bicelles 分子名称: Toll-like receptor 4 著者 Mineev, K.S, Goncharuk, S.A, Goncharuk, M.V, Arseniev, A.S. 登録日 2017-02-28 公開日 2017-09-06 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Spatial structure of TLR4 transmembrane domain in bicelles provides the insight into the receptor activation mechanism. Sci Rep, 7, 2017
6DLM	DHD127 分子名称: DHD127_A, DHD127_B 著者 Bick, M.J, Chen, Z, Baker, D. 登録日 2018-06-01 公開日 2018-12-19 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.753 Å) 主引用文献 Programmable design of orthogonal protein heterodimers. Nature, 565, 2019
6XHB	Crystal Structure of wild-type KRAS (GMPPNP-bound) in complex with RAS-binding domain (RBD) and cysteine-rich domain (CRD) of RAF1/CRAF (crystal form II) 分子名称: CHLORIDE ION, GLYCEROL, GTPase KRas, ... 著者 Tran, T.H, Chan, A.H, Dharmaiah, S, Simanshu, D.K. 登録日 2020-06-18 公開日 2021-01-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation. Nat Commun, 12, 2021
1GRW	C. elegans major sperm protein 分子名称: MAJOR SPERM PROTEIN 31/40/142 著者 Baker, A.M.E, Roberts, T.M, Stewart, M. 登録日 2001-12-18 公開日 2002-06-13 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 2.6 A Resolution Crystal Structure of Helices of the Motile Major Sperm Protein (Msp) of Caenorhabditis Elegans J.Mol.Biol., 319, 2002
5L7S	Crystal structure of RXLR effector PexRD54 from Phytophthora infestans 分子名称: Secreted RxLR effector peptide protein 著者 Maqbool, A, Hughes, R.K, Banfield, M.J. 登録日 2016-06-03 公開日 2016-08-03 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural Basis of Host Autophagy-related Protein 8 (ATG8) Binding by the Irish Potato Famine Pathogen Effector Protein PexRD54. J.Biol.Chem., 291, 2016
6XM4	Structure of SARS-CoV-2 spike at pH 5.5, single RBD up, conformation 2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein 著者 Zhou, T, Tsybovsky, Y, Olia, A, Kwong, P.D. 登録日 2020-06-29 公開日 2020-08-12 最終更新日 2021-12-15 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains. Cell Host Microbe, 28, 2020
6KIX	Cryo-EM structure of human MLL1-NCP complex, binding mode1 分子名称: DNA (145-MER), GLUTAMINE, Histone H2A, ... 著者 Huang, J, Xue, H, Yao, T. 登録日 2019-07-20 公開日 2019-09-11 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structural basis of nucleosome recognition and modification by MLL methyltransferases. Nature, 573, 2019
1H2B	Crystal Structure of the Alcohol Dehydrogenase from the Hyperthermophilic Archaeon Aeropyrum pernix at 1.65A Resolution 分子名称: ALCOHOL DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), OCTANOIC ACID (CAPRYLIC ACID), ... 著者 Guy, J.E, Isupov, M.N, Littlechild, J.A. 登録日 2002-08-02 公開日 2003-08-28 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 The structure of an alcohol dehydrogenase from the hyperthermophilic archaeon Aeropyrum pernix. J.Mol.Biol., 331, 2003
6DO4	KLHDC2 ubiquitin ligase in complex with SelS C-end degron 分子名称: Kelch domain-containing protein 2, SELS C-END DEGRON 著者 Rusnac, D.V, Lin, H.C, Yen, H.C.S, Zheng, N. 登録日 2018-06-08 公開日 2018-12-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Recognition of the Diglycine C-End Degron by CRL2KLHDC2Ubiquitin Ligase. Mol. Cell, 72, 2018
6XR3	X-ray Structure of SARS-CoV-2 main protease bound to GRL-024-20 at 1.45 A 分子名称: 3C-like proteinase, N-[(2S)-1-({(1S,2S)-1-(1,3-benzothiazol-2-yl)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide 著者 Anson, B, Ghosh, A.K, Mesecar, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2020-07-10 公開日 2020-08-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 X-ray Structure of SARS-CoV-2 main protease bound to GRL-024-20 at 1.45 A To Be Published
6KIV	Cryo-EM structure of human MLL1-ubNCP complex (4.0 angstrom) 分子名称: DNA (145-MER), Histone H2A, Histone H2B 1.1, ... 著者 Huang, J, Xue, H, Yao, T. 登録日 2019-07-20 公開日 2019-09-11 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structural basis of nucleosome recognition and modification by MLL methyltransferases. Nature, 573, 2019

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