7YUP
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![BU of 7yup by Molmil](/molmil-images/mine/7yup) | MtaLon-Apo for the spiral oligomers of pentamer | 分子名称: | Lon protease | 著者 | Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I. | 登録日 | 2022-08-17 | 公開日 | 2023-10-25 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine. Nat Commun, 14, 2023
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7YPH
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![BU of 7yph by Molmil](/molmil-images/mine/7yph) | Open-spiral pentamer of the substrate-free Lon protease with a Y224S mutation | 分子名称: | Lon protease, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | 著者 | Li, S, Hsieh, K.Y, Kuo, C.I, Lee, S.H, Ho, M.R, Wang, C.H, Zhang, K, Chang, C.I. | 登録日 | 2022-08-03 | 公開日 | 2023-10-25 | 最終更新日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (3.68 Å) | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine. Nat Commun, 14, 2023
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7YUT
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![BU of 7yut by Molmil](/molmil-images/mine/7yut) | MtaLon-Apo for the spiral oligomers of hexamer | 分子名称: | Lon protease | 著者 | Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I. | 登録日 | 2022-08-17 | 公開日 | 2023-10-25 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine. Nat Commun, 14, 2023
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7YUX
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![BU of 7yux by Molmil](/molmil-images/mine/7yux) | MtaLon-ADP for the spiral oligomers of hexamer | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lon protease | 著者 | Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I. | 登録日 | 2022-08-18 | 公開日 | 2023-10-25 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine. Nat Commun, 14, 2023
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6FCF
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![BU of 6fcf by Molmil](/molmil-images/mine/6fcf) | CHK1 KINASE IN COMPLEX WITH COMPOUND 44 | 分子名称: | 4-[[(2~{R},3~{S})-2-methylpiperidin-3-yl]amino]-2-phenyl-thieno[3,2-c]pyridine-7-carboxamide, SULFATE ION, Serine/threonine-protein kinase Chk1 | 著者 | Read, J.A, Breed, J. | 登録日 | 2017-12-20 | 公開日 | 2018-01-17 | 最終更新日 | 2018-02-21 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Adventures in Scaffold Morphing: Discovery of Fused Ring Heterocyclic Checkpoint Kinase 1 (CHK1) Inhibitors. J. Med. Chem., 61, 2018
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6FCK
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![BU of 6fck by Molmil](/molmil-images/mine/6fck) | CHK1 KINASE IN COMPLEX WITH COMPOUND 13 | 分子名称: | 2-phenyl-4-[[(3~{S})-piperidin-3-yl]amino]-1~{H}-indole-7-carboxamide, SULFATE ION, Serine/threonine-protein kinase Chk1 | 著者 | Read, J.A, Breed, J. | 登録日 | 2017-12-20 | 公開日 | 2018-01-17 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Adventures in Scaffold Morphing: Discovery of Fused Ring Heterocyclic Checkpoint Kinase 1 (CHK1) Inhibitors. J. Med. Chem., 61, 2018
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6FC8
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![BU of 6fc8 by Molmil](/molmil-images/mine/6fc8) | CHK1 KINASE IN COMPLEX WITH COMPOUND 13 | 分子名称: | 2-(3-fluorophenyl)-4-[[(3~{S})-piperidin-3-yl]amino]thieno[3,2-c]pyridine-7-carboxamide, SULFATE ION, Serine/threonine-protein kinase Chk1 | 著者 | Read, J.A, Breed, J. | 登録日 | 2017-12-20 | 公開日 | 2018-01-17 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Adventures in Scaffold Morphing: Discovery of Fused Ring Heterocyclic Checkpoint Kinase 1 (CHK1) Inhibitors. J. Med. Chem., 61, 2018
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1Z96
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![BU of 1z96 by Molmil](/molmil-images/mine/1z96) | Crystal structure of the Mud1 UBA domain | 分子名称: | UBA-domain protein mud1 | 著者 | Trempe, J.-F, Brown, N.R, Lowe, E.D, Noble, M.E.M, Gordon, C, Campbell, I.D, Johnson, L.N, Endicott, J.A. | 登録日 | 2005-03-31 | 公開日 | 2005-10-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Mechanism of Lys48-linked polyubiquitin chain recognition by the Mud1 UBA domain Embo J., 24, 2005
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6GY2
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6H2V
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![BU of 6h2v by Molmil](/molmil-images/mine/6h2v) | Crystal structure of human METTL5-TRMT112 complex, the 18S rRNA m6A1832 methyltransferase at 2.5A resolution | 分子名称: | 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, DI(HYDROXYETHYL)ETHER, ... | 著者 | van Tran, N, Graille, M. | 登録日 | 2018-07-16 | 公開日 | 2019-07-31 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | The human 18S rRNA m6A methyltransferase METTL5 is stabilized by TRMT112. Nucleic Acids Res., 47, 2019
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8ADD
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![BU of 8add by Molmil](/molmil-images/mine/8add) | Viral tegument-like DUBs | 分子名称: | ATP-dependent DNA helicase | 著者 | Erven, I, Abraham, E.T, Hermanns, T, Hofmann, K, Baumann, U. | 登録日 | 2022-07-08 | 公開日 | 2023-02-15 | 最終更新日 | 2024-09-04 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A widely distributed family of eukaryotic and bacterial deubiquitinases related to herpesviral large tegument proteins. Nat Commun, 13, 2022
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6H2U
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![BU of 6h2u by Molmil](/molmil-images/mine/6h2u) | Crystal structure of human METTL5-TRMT112 complex, the 18S rRNA m6A1832 methyltransferase at 1.6A resolution | 分子名称: | 1,2-ETHANEDIOL, Methyltransferase-like protein 5, Multifunctional methyltransferase subunit TRM112-like protein, ... | 著者 | van Tran, N, Graille, M. | 登録日 | 2018-07-16 | 公開日 | 2019-07-31 | 最終更新日 | 2019-09-18 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The human 18S rRNA m6A methyltransferase METTL5 is stabilized by TRMT112. Nucleic Acids Res., 47, 2019
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2AEO
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![BU of 2aeo by Molmil](/molmil-images/mine/2aeo) | Crystal structure of cisplatinated bovine Cu,Zn superoxide dismutase | 分子名称: | COPPER (II) ION, Cisplatin, Superoxide dismutase [Cu-Zn], ... | 著者 | Calderone, V, Casini, A, Mangani, S, Messori, L, Orioli, P.L. | 登録日 | 2005-07-23 | 公開日 | 2006-05-02 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural investigation of cisplatin-protein interactions: selective platination of His19 in a cuprozinc superoxide dismutase. Angew. Chem. Int. Ed. Engl., 45, 2006
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2A4J
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![BU of 2a4j by Molmil](/molmil-images/mine/2a4j) | Solution structure of the C-terminal domain (T94-Y172) of the human centrin 2 in complex with a 17 residues peptide (P1-XPC) from xeroderma pigmentosum group C protein | 分子名称: | 17-mer peptide P1-XPC from DNA-repair protein complementing XP-C cells, Centrin 2 | 著者 | Yang, A, Miron, S, Mouawad, L, Duchambon, P, Blouquit, Y, Craescu, C.T. | 登録日 | 2005-06-29 | 公開日 | 2005-07-12 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Flexibility and plasticity of human centrin 2 binding to the xeroderma pigmentosum group C protein (XPC) from nuclear excision repair. Biochemistry, 45, 2006
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7VG2
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7VG3
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6L4P
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![BU of 6l4p by Molmil](/molmil-images/mine/6l4p) | Crystal structure of the complex between the axonemal outer-arm dynein light chain-1 and microtubule binding domain of gamma heavy chain | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Dynein light chain 1, axonemal, ... | 著者 | Toda, A, Nishikawa, Y, Tanaka, H, Yagi, T, Kurisu, G. | 登録日 | 2019-10-19 | 公開日 | 2020-02-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.703 Å) | 主引用文献 | The complex of outer-arm dynein light chain-1 and the microtubule-binding domain of the gamma heavy chain shows how axonemal dynein tunes ciliary beating. J.Biol.Chem., 295, 2020
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4ZKP
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7VKB
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![BU of 7vkb by Molmil](/molmil-images/mine/7vkb) | Crystal structure of the a bacterial kinase complex | 分子名称: | DI(HYDROXYETHYL)ETHER, HipA (Persistence to inhibition of murein or DNA biosynthesis), HipA_C domain-containing protein, ... | 著者 | Zhen, X, Ouyang, S.Y. | 登録日 | 2021-09-29 | 公開日 | 2022-06-29 | 最終更新日 | 2022-08-03 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Molecular mechanism of toxin neutralization in the HipBST toxin-antitoxin system of Legionella pneumophila. Nat Commun, 13, 2022
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4ZNF
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8C6C
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![BU of 8c6c by Molmil](/molmil-images/mine/8c6c) | Light SFX structure of D.m(6-4)photolyase at 300ps time delay | 分子名称: | Cryptochrome-1, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL | 著者 | Cellini, A, Kumar, M, Nimmrich, A, Mutisya, J, Furrer, A, Beale, E.V, Carrillo, M, Malla, T.N, Maj, P, Dworkowskic, F, Cirelli, C, Ozerovi, D, Bacellar, C, Strandfuss, J, Weinert, T, Ihalainen, J.A, Yuan Wahlgren, W, Westenhoff, S. | 登録日 | 2023-01-11 | 公開日 | 2023-11-01 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Directed ultrafast conformational changes accompany electron transfer in a photolyase as resolved by serial crystallography. Nat.Chem., 16, 2024
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8C1U
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![BU of 8c1u by Molmil](/molmil-images/mine/8c1u) | SFX structure of D.m(6-4)photolyase | 分子名称: | Cryptochrome-1, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL | 著者 | Cellini, A, Kumar, M, Nimmrich, A, Mutisya, J, Furrer, A, Beale, E.V, Carrillo, M, Malla, T.N, Maj, P, Dworkowskic, F, Cirelli, C, Ozerovi, D, Bacellar, C, Strandfuss, J, Weinert, T, Ihalainen, J.A, Yuan Wahlgren, W, Westenhoff, S. | 登録日 | 2022-12-21 | 公開日 | 2023-11-01 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Directed ultrafast conformational changes accompany electron transfer in a photolyase as resolved by serial crystallography. Nat.Chem., 16, 2024
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8C6H
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![BU of 8c6h by Molmil](/molmil-images/mine/8c6h) | Light SFX structure of D.m(6-4)photolyase at 2ps time delay | 分子名称: | Cryptochrome-1, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL | 著者 | Cellini, A, Kumar, M, Nimmrich, A, Mutisya, J, Furrer, A, Beale, E.V, Carrillo, M, Malla, T.N, Maj, P, Dworkowskic, F, Cirelli, C, Ozerovi, D, Bacellar, C, Strandfuss, J, Weinert, T, Ihalainen, J.A, Yuan Wahlgren, W, Westenhoff, S. | 登録日 | 2023-01-11 | 公開日 | 2023-11-01 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Directed ultrafast conformational changes accompany electron transfer in a photolyase as resolved by serial crystallography. Nat.Chem., 16, 2024
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8C2E
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8C69
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![BU of 8c69 by Molmil](/molmil-images/mine/8c69) | Light SFX structure of D.m(6-4)photolyase at 100 microsecond time delay | 分子名称: | Cryptochrome-1, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL | 著者 | Cellini, A, Kumar, M, Nimmrich, A, Mutisya, J, Furrer, A, Beale, E.V, Carrillo, M, Malla, T.N, Maj, P, Dworkowskic, F, Cirelli, C, Ozerovi, D, Bacellar, C, Strandfuss, J, Weinert, T, Ihalainen, J.A, Yuan Wahlgren, W, Westenhoff, S. | 登録日 | 2023-01-11 | 公開日 | 2023-11-01 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Directed ultrafast conformational changes accompany electron transfer in a photolyase as resolved by serial crystallography. Nat.Chem., 16, 2024
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