2AEO

Crystal structure of cisplatinated bovine Cu,Zn superoxide dismutase

Summary for 2AEO

• Entry DOI: 10.2210/pdb2aeo/pdb
• Related: 1SXS
• Descriptor: Superoxide dismutase [Cu-Zn], COPPER (II) ION, ZINC ION, ... (5 entities in total)
• Functional Keywords: cisplatin, platinum, sod, cu, zn sod, metal based drugs, cancer, protein, oxidoreductase
• Biological source: Bos taurus (cattle)
• Cellular location: Cytoplasm: P00442
• Total number of polymer chains: 2
• Total formula weight: 32004.67

Authors

Calderone, V.,Casini, A.,Mangani, S.,Messori, L.,Orioli, P.L. (deposition date: 2005-07-23, release date: 2006-05-02, Last modification date: 2024-10-30)

• Primary citation: Calderone, V.,Casini, A.,Mangani, S.,Messori, L.,Orioli, P.L.; Structural investigation of cisplatin-protein interactions: selective platination of His19 in a cuprozinc superoxide dismutase.; Angew. Chem. Int. Ed. Engl., 45:1267-1269, 2006; PubMed: 16416478; DOI: 10.1002/anie.200502599

Experimental method

X-RAY DIFFRACTION (1.8 Å)