PDB: 9760 件ウェブページステータス検索Chemie searchBIRD

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6O3J	Crystal structure of the Fab fragment of the human HIV-1 neutralizing antibody PGZL1 in complex with its MPER peptide epitope (region 671-683 of HIV-1 gp41) and phosphatidic acid (06:0 PA) 分子名称: (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, (4S)-2-METHYL-2,4-PENTANEDIOL, MPER peptide, ... 著者 Irimia, A, Wilson, I.A. 登録日 2019-02-26 公開日 2019-12-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.416 Å) 主引用文献 An MPER antibody neutralizes HIV-1 using germline features shared among donors. Nat Commun, 10, 2019
6O3L	Crystal structure of the Fab fragment of the human HIV-1 neutralizing antibody PGZL1.H4K3 in complex with its MPER peptide epitope (region 671-683 of HIV-1 gp41). 分子名称: GLYCEROL, MPER peptide, region 671-683 of HIV-1 gp41, ... 著者 Irimia, A, Wilson, I.A. 登録日 2019-02-26 公開日 2019-12-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 An MPER antibody neutralizes HIV-1 using germline features shared among donors. Nat Commun, 10, 2019
5ESV	Crystal Structure of Broadly Neutralizing Antibody CH03, Isolated from Donor CH0219, in Complex with Scaffolded Trimeric HIV-1 Env V1V2 Domain from the Clade C Superinfecting Strain of Donor CAP256. 分子名称: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase,Envelope glycoprotein gp160, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Gorman, J, Yang, M, Kwong, P.D. 登録日 2015-11-17 公開日 2015-12-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.105 Å) 主引用文献 Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design. Nat.Struct.Mol.Biol., 23, 2016
8GKJ	Crystal Structure of the Murine MUC16 Specific Antibody AR9.6 分子名称: MUC16 antibody AR9.6 heavy chain, MUC16 antibody AR9.6 light chain 著者 Brooks, C.L, Aguilar, E.N. 登録日 2023-03-19 公開日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structure of the Murine MUC16 Specific Antibody AR9.6 To Be Published
7TH3	Single-domain VHH intrabodies neutralize ricin toxin 分子名称: Ricin chain A, VHH antibody 著者 Rudolph, M.J. 登録日 2022-01-10 公開日 2022-10-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.292 Å) 主引用文献 Single-domain antibodies neutralize ricin toxin intracellularly by blocking access to ribosomal P-stalk proteins. J.Biol.Chem., 298, 2022
7TH2	Single-domain VHH intrabodies neutralize ricin toxin 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... 著者 Rudolph, M.J, Mantis, N. 登録日 2022-01-10 公開日 2022-10-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.838 Å) 主引用文献 Single-domain antibodies neutralize ricin toxin intracellularly by blocking access to ribosomal P-stalk proteins. J.Biol.Chem., 298, 2022
6O3K	Crystal structure of the unbound Fab fragment of the human HIV-1 neutralizing antibody PGZL1.H4K3 分子名称: GLYCEROL, PGZL1.H4K3 heavy chain, PGZL1.H4K3 light chain, ... 著者 Irimia, A, Wilson, I.A. 登録日 2019-02-26 公開日 2019-12-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.451 Å) 主引用文献 An MPER antibody neutralizes HIV-1 using germline features shared among donors. Nat Commun, 10, 2019
6O3U	Crystal structure of the Fab fragment of the human HIV-1 neutralizing antibody PGZL1.H4K3 in complex with 06:0 PA 分子名称: (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, GLYCEROL, PGZL1.H4K3 heavy chain, ... 著者 Irimia, A, Wilson, I.A. 登録日 2019-02-27 公開日 2019-12-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.105 Å) 主引用文献 An MPER antibody neutralizes HIV-1 using germline features shared among donors. Nat Commun, 10, 2019
6X78	Vaccine-elicited mouse FP-targeting neutralizing antibody vFP48.03 in complex with HIV fusion peptide (residue 512-519) 分子名称: HIV fusion peptide 512-519 V2, SULFATE ION, antibody vFP48.03 heavy chain, ... 著者 Xu, K, Kwong, P.D. 登録日 2020-05-29 公開日 2021-06-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.359 Å) 主引用文献 Distinct Classes of HIV-1 Cross-Clade Neutralizing Antibodies Targeting Fusion Peptide Elicited in Mice by Diverse Immunization Regimens To Be Published
6X7W	Vaccine-elicited mouse FP-targeting neutralizing antibody vFP49.02 in complex with HIV fusion peptide (residue 512-519) 分子名称: HIV fusion peptide 512-519, SULFATE ION, antibody vFP49.02 heavy chain, ... 著者 Xu, K, Kwong, P.D. 登録日 2020-05-30 公開日 2021-06-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Distinct Classes of HIV-1 Cross-Clade Neutralizing Antibodies Targeting Fusion Peptide Elicited in Mice by Diverse Immunization Regimens To Be Published
5ESZ	Crystal Structure of Broadly Neutralizing Antibody CH04, Isolated from Donor CH0219, in Complex with Scaffolded Trimeric HIV-1 Env V1V2 Domain from the Clade AE Strain A244 分子名称: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase,Envelope glycoprotein gp160, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH04 Heavy Chain, ... 著者 Gorman, J, Yang, M, Kwong, P.D. 登録日 2015-11-17 公開日 2015-12-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (4.191 Å) 主引用文献 Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design. Nat. Struct. Mol. Biol., 23, 2016
5FEH	Crystal structure of PCT64_35B, a broadly neutralizing anti-HIV antibody 分子名称: 1,2-ETHANEDIOL, PCT64_26 Fab heavy chain, PCT64_26 Fab light chain, ... 著者 Murrell, S, Wilson, I.A. 登録日 2015-12-17 公開日 2017-08-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 HIV Envelope Glycoform Heterogeneity and Localized Diversity Govern the Initiation and Maturation of a V2 Apex Broadly Neutralizing Antibody Lineage. Immunity, 47, 2017
4O5I	Crystal structure of broadly neutralizing antibody F045-092 in complex with A/Victoria/361/2011 (H3N2) influenza hemagglutinin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab F045-092 heavy chain, ... 著者 Lee, P.S, Wilson, I.A. 登録日 2013-12-19 公開日 2014-04-16 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (6.501 Å) 主引用文献 Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus. Nat Commun, 5, 2014
4O5L	Crystal structure of broadly neutralizing antibody F045-092 分子名称: Fab F045-092 heavy chain, Fab F045-092 light chain, PHOSPHATE ION 著者 Lee, P.S, Wilson, I.A. 登録日 2013-12-19 公開日 2014-04-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5045 Å) 主引用文献 Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus. Nat Commun, 5, 2014
5ANY	Electron cryo-microscopy of chikungunya virus in complex with neutralizing antibody Fab CHK265 分子名称: E1, E2, FAB, ... 著者 Fox, J.M, Long, F, Edeling, M.A, Lin, H, Duijl-Richter, M, Fong, R.H, Kahle, K.M, Smit, J.M, Jin, J, Simmons, G, Doranz, B.J, Crowe, J.E, Fremont, D.H, Rossmann, M.G, Diamond, M.S. 登録日 2015-09-08 公開日 2015-11-25 最終更新日 2018-10-03 実験手法 ELECTRON MICROSCOPY (16.9 Å) 主引用文献 Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress. Cell(Cambridge,Mass.), 163, 2015
4N0Y	Structure of the Hepatitis C Envelope Glycoprotein E1 antigenic region 314-324 bound to the cross-neutralizing antibody IGH526 分子名称: CHLORIDE ION, GLYCEROL, HCV E1 peptide, ... 著者 Kong, L, Wilson, I.A. 登録日 2013-10-02 公開日 2015-04-01 最終更新日 2015-08-26 実験手法 X-RAY DIFFRACTION (1.749 Å) 主引用文献 Structure of Hepatitis C Virus Envelope Glycoprotein E1 Antigenic Site 314-324 in Complex with Antibody IGH526. J.Mol.Biol., 427, 2015
7WI0	SARS-CoV-2 Omicron variant spike in complex with three human neutralizing antibodies 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, IG c1437_light_IGLV1-40_IGLJ1, IG c934_light_IGKV1-5_IGKJ1, ... 著者 Zheng, Q, Li, S, Sun, H, Zheng, Z, Wang, S. 登録日 2022-01-01 公開日 2022-06-22 実験手法 ELECTRON MICROSCOPY (3.82 Å) 主引用文献 Three SARS-CoV-2 antibodies provide broad and synergistic neutralization against variants of concern, including Omicron. Cell Rep, 39, 2022
7WHZ	SARS-CoV-2 spike protein in complex with three human neutralizing antibodies 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, IG c1437_light_IGLV1-40_IGLJ1, IG c934_light_IGKV1-5_IGKJ1, ... 著者 Zheng, Q, Li, S, Sun, H, Zheng, Z, Wang, S. 登録日 2022-01-01 公開日 2022-06-22 実験手法 ELECTRON MICROSCOPY (3.42 Å) 主引用文献 Three SARS-CoV-2 antibodies provide broad and synergistic neutralization against variants of concern, including Omicron. Cell Rep, 39, 2022
7F2S	Crystal structure of anti S-gatifloxacin antibody Fab fragment apo form 分子名称: 1,2-ETHANEDIOL, Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, ... 著者 Wang, L.T, Jiao, W.Y, Shen, X, Lei, H.T. 登録日 2021-06-14 公開日 2021-12-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Conformational adaptability determining antibody recognition to distomer: structure analysis of enantioselective antibody against chiral drug gatifloxacin Rsc Adv, 11, 2021
7F35	Crystal structure of anti S-gatifloxacin antibody Fab fragment in complex with S-gatifloxacin 分子名称: 1,2-ETHANEDIOL, 1-cyclopropyl-6-fluoro-8-methoxy-7-[(3S)-3-methylpiperazin-1-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, Antibody Fab fragment heavy chain, ... 著者 Wang, L.T, Jiao, W.Y, Shen, X, Lei, H.T. 登録日 2021-06-15 公開日 2021-12-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Conformational adaptability determining antibody recognition to distomer: structure analysis of enantioselective antibody against chiral drug gatifloxacin Rsc Adv, 11, 2021
6N32	Anti-HIV-1 Fab 2G12 re-refinement 分子名称: Fab 2G12 heavy chain, Fab 2G12 light chain, SULFATE ION 著者 Calarese, D.A, Stanfield, R.L, Wilson, I.A. 登録日 2018-11-14 公開日 2018-11-28 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Antibody domain exchange is an immunological solution to carbohydrate cluster recognition. Science, 300, 2003
7WKI	Structure of the ultra-affinity complex between CFH and a nanobody 分子名称: Anti-CFH nanobody (VHH), Complement factor H 著者 Caaveiro, J.M.M, Yokoo, T, Tsumoto, K. 登録日 2022-01-10 公開日 2022-11-23 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Antibody recognition of complement factor H reveals a flexible loop involved in atypical hemolytic uremic syndrome pathogenesis. J.Biol.Chem., 298, 2022
4X80	Crystal Structure of murine 7B4 Fab monoclonal antibody against ADAMTS5 分子名称: IgG1 7B4 FAB Heavy chain, IgG1 7B4 FAB Light Chain 著者 Larkin, J, Lohr, T.A, Elefante, L, Shearin, J, Matico, R, Su, J.-L, Xue, Y, Liu, F, Genell, C, Miller, R.E, Tran, P.B, Malfait, A.-M, Maier, C.C, Matheny, C.J. 登録日 2014-12-09 公開日 2015-04-08 最終更新日 2015-08-05 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Translational development of an ADAMTS-5 antibody for osteoarthritis disease modification. Osteoarthr. Cartil., 23, 2015
4X8J	Crystal Structure of murine 12F4 Fab monoclonal antibody against ADAMTS5 分子名称: 12F4 FAB Heavy chain, 12F4 FAB Light chain, NONAETHYLENE GLYCOL, ... 著者 Larkin, J, Lohr, T.A, Elefante, L, Shearin, J, Matico, R, Su, J.-L, Xue, Y, Liu, F, Genell, C, Miller, R.E, Tran, P.B, Malfait, A.-M, Maier, C.C, Matheny, C.J. 登録日 2014-12-10 公開日 2015-04-08 最終更新日 2015-08-05 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Translational development of an ADAMTS-5 antibody for osteoarthritis disease modification. Osteoarthr. Cartil., 23, 2015
6XE1	Structure of SARS-CoV-2 spike protein receptor binding domain in complex with a potent neutralizing antibody, CV30 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CV30 Fab Heavy chain, CV30 Fab Kappa chain, ... 著者 Hurlburt, N.K, Pancera, M. 登録日 2020-06-11 公開日 2020-07-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structural basis for potent neutralization of SARS-CoV-2 and role of antibody affinity maturation. Nat Commun, 11, 2020

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