PDB: 19129 件ウェブページステータス検索Chemie searchBIRD

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8UUH	SARS-CoV-2 papain-like protease (PLpro) with inhibitor Jun12199 分子名称: 5-[2-(dimethylamino)ethoxy]-2-methyl-N-[(1R)-1-{(3M,5P)-3-(1-methyl-1H-pyrazol-4-yl)-5-[1-(propan-2-yl)-1H-pyrazol-4-yl]phenyl}ethyl]benzamide, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Ansari, A, Tan, B, Ruiz, F.X, Arnold, E, Wang, J. 登録日 2023-11-01 公開日 2024-04-03 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Design of a SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model. Science, 383, 2024
8WT8	Cryo-EM structure of the IS621 recombinase in complex with bridge RNA, donor DNA, and target DNA in the post-strand exchange state (Holliday junction intermediate) 分子名称: IS621 transposase, MAGNESIUM ION, bridge RNA, ... 著者 Hiraizumi, M, Yamashita, K, Nishimasu, H. 登録日 2023-10-18 公開日 2024-06-26 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural mechanism of bridge RNA-guided recombination. Nature, 630, 2024
2D4X	Crystal structure of a 26K fragment of HAP3 (FlgL) 分子名称: Flagellar hook-associated protein 3 著者 Imada, K, Matsunami, H, Samatey, A.F, Nagashima, S, Namba, K. 登録日 2005-10-25 公開日 2006-11-14 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of the bacterial flagellar hook-filament junction To be Published
8UZ1	Straight actin filament from Arp2/3 branch junction sample (ADP-BeFx) 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 Chavali, S.S, Chou, S.Z, Sindelar, C.V. 登録日 2023-11-14 公開日 2024-01-31 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Cryo-EM structures reveal how phosphate release from Arp3 weakens actin filament branches formed by Arp2/3 complex. Nat Commun, 15, 2024
4OET	Crystal structure of NikZ from Campylobacter jejuni, unliganded form 分子名称: GLYCEROL, Putative peptide ABC-transport system periplasmic peptide-binding protein 著者 Lebrette, H, Cavazza, C. 登録日 2014-01-13 公開日 2014-10-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Promiscuous nickel import in human pathogens: structure, thermodynamics, and evolution of extracytoplasmic nickel-binding proteins. Structure, 22, 2014
6HRC	Outward-facing PglK with ATPgammaS bound 分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, WlaB protein 著者 Perez, C, Locher, K.P. 登録日 2018-09-26 公開日 2019-03-06 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structure of Outward-Facing PglK and Molecular Dynamics of Lipid-Linked Oligosaccharide Recognition and Translocation. Structure, 27, 2019
8ICD	REGULATION OF AN ENZYME BY PHOSPHORYLATION AT THE ACTIVE SITE 分子名称: ISOCITRATE DEHYDROGENASE, ISOCITRIC ACID, MAGNESIUM ION 著者 Hurley, J.H, Dean, A.M, Sohl, J.L, Koshlandjunior, D.E, Stroud, R.M. 登録日 1990-05-30 公開日 1991-10-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Regulation of an enzyme by phosphorylation at the active site. Science, 249, 1990
4OEU	Crystal structure of NikZ from Campylobacter jejuni in complex with Ni(L-His) 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, HISTIDINE, ... 著者 Lebrette, H, Cavazza, C. 登録日 2014-01-13 公開日 2014-10-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Promiscuous nickel import in human pathogens: structure, thermodynamics, and evolution of extracytoplasmic nickel-binding proteins. Structure, 22, 2014
4OEV	Crystal structure of NikZ from Campylobacter jejuni in complex with Ni(II) ion 分子名称: GLYCEROL, NICKEL (II) ION, OXALATE ION, ... 著者 Lebrette, H, Cavazza, C. 登録日 2014-01-13 公開日 2014-10-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Promiscuous nickel import in human pathogens: structure, thermodynamics, and evolution of extracytoplasmic nickel-binding proteins. Structure, 22, 2014
3E3U	Crystal structure of Mycobacterium tuberculosis peptide deformylase in complex with inhibitor 分子名称: N-[(2R)-2-{[(2S)-2-(1,3-benzoxazol-2-yl)pyrrolidin-1-yl]carbonyl}hexyl]-N-hydroxyformamide, NICKEL (II) ION, Peptide deformylase 著者 Meng, W, Xu, M, Pan, S, Koehn, J. 登録日 2008-08-08 公開日 2009-01-20 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Peptide deformylase inhibitors of Mycobacterium tuberculosis: synthesis, structural investigations, and biological results. Bioorg.Med.Chem.Lett., 18, 2008
6OQP	U-AITx-Ate1 分子名称: SER-LYS-TRP-ILE-CYS-ALA-ASN-ARG-SER-VAL-CYS-PRO-ILE 著者 Elnahriry, K.A, Wai, D.C.C, Norton, R.S. 登録日 2019-04-28 公開日 2019-07-31 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Structural and functional characterisation of a novel peptide from the Australian sea anemone Actinia tenebrosa. Toxicon, 168, 2019
3ETQ	X-ray structure of cysteine-free fragment of mHCN2 C-terminal region from amino acids 443-630 including C508N, C584S, and C601S mutations 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 著者 Flynn, G.E. 登録日 2008-10-08 公開日 2009-06-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Mapping the structure and conformational movements of proteins with transition metal ion FRET. Nat.Methods, 6, 2009
6P79	Engineered single chain antibody C9+C14 ScFv 分子名称: Engineered antibody heavy chain, Engineered antibody light chain 著者 Zhang, Y, Li, W, Marshall, N. 登録日 2019-06-05 公開日 2020-04-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.583 Å) 主引用文献 Computer-based Engineering of Thermostabilized Antibody Fragments. Aiche J, 66, 2020
4IMK	Uncrossed Fab binding to human Angiopoietin 2 分子名称: GLYCEROL, Heavy Chain, Light Chain, ... 著者 Fenn, S, Schiller, C, Griese, J.J, Hopfner, K.-P, Kettenberger, H. 登録日 2013-01-03 公開日 2013-04-17 最終更新日 2013-05-22 実験手法 X-RAY DIFFRACTION (2.202 Å) 主引用文献 Crystal Structure of an Anti-Ang2 CrossFab Demonstrates Complete Structural and Functional Integrity of the Variable Domain. Plos One, 8, 2013
6PLC	Structure of human DNA polymerase eta complexed with 8OA in the template base paired with incoming non-hydrolyzable GTP 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(A38)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... 著者 Koag, M.C, Lee, S. 登録日 2019-06-30 公開日 2020-04-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Mutagenesis mechanism of the major oxidative adenine lesion 7,8-dihydro-8-oxoadenine. Nucleic Acids Res., 48, 2020
4IML	CrossFab binding to human Angiopoietin 2 分子名称: Crossed heavy chain (VH-Ckappa), Crossed light chain (VL-CH1), GLYCEROL 著者 Fenn, S, Schiller, C, Griese, J, Hopfner, K.-P, Kettenberger, H. 登録日 2013-01-03 公開日 2013-04-17 最終更新日 2013-05-22 実験手法 X-RAY DIFFRACTION (2.931 Å) 主引用文献 Crystal Structure of an Anti-Ang2 CrossFab Demonstrates Complete Structural and Functional Integrity of the Variable Domain. Plos One, 8, 2013
6PZS	Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with JR005 分子名称: 4-[({[(1R,2R,5R)-6,6-dimethylbicyclo[3.1.1]heptan-2-yl]methyl}amino)methyl]-N-hydroxybenzamide, CHLORIDE ION, Hdac6 protein, ... 著者 Osko, J.D, Christianson, D.W. 登録日 2019-08-01 公開日 2020-02-05 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Exploring Structural Determinants of Inhibitor Affinity and Selectivity in Complexes with Histone Deacetylase 6. J.Med.Chem., 63, 2020
6PZR	Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with Resminostat 分子名称: 1,2-ETHANEDIOL, Hdac6 protein, IODIDE ION, ... 著者 Osko, J.D, Christianson, D.W. 登録日 2019-08-01 公開日 2020-02-05 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Exploring Structural Determinants of Inhibitor Affinity and Selectivity in Complexes with Histone Deacetylase 6. J.Med.Chem., 63, 2020
6Q0Z	Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with JS28 分子名称: 2-(4-bromophenyl)-N-hydroxy-1,3-oxazole-4-carboxamide, Hdac6 protein, POTASSIUM ION, ... 著者 Osko, J.D, Christianson, D.W. 登録日 2019-08-02 公開日 2020-02-05 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Exploring Structural Determinants of Inhibitor Affinity and Selectivity in Complexes with Histone Deacetylase 6. J.Med.Chem., 63, 2020
6PZO	Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with YX-153 分子名称: Hdac6 protein, N-{[4-(hydroxycarbamoyl)phenyl]methyl}-2-(trifluoromethyl)pyridine-3-carboxamide, POTASSIUM ION, ... 著者 Osko, J.D, Christianson, D.W. 登録日 2019-08-01 公開日 2020-02-05 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Exploring Structural Determinants of Inhibitor Affinity and Selectivity in Complexes with Histone Deacetylase 6. J.Med.Chem., 63, 2020
6PZU	Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with AP-1-62-A 分子名称: Hdac6 protein, N-[(benzyloxy)carbonyl]-L-leucyl-N-{[4-(hydroxycarbamoyl)phenyl]methyl}-L-alaninamide, POTASSIUM ION, ... 著者 Osko, J.D, Christianson, D.W. 登録日 2019-08-01 公開日 2020-02-05 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Exploring Structural Determinants of Inhibitor Affinity and Selectivity in Complexes with Histone Deacetylase 6. J.Med.Chem., 63, 2020
6Q3Q	Arabidopsis OM64 TPR domain 分子名称: GLY-SER-LYS-MET-GLU-GLU-VAL-ASP, GLYCEROL, Outer envelope protein 64, ... 著者 Schwenkert, S. 登録日 2018-12-04 公開日 2018-12-19 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Phosphorylation of the outer membrane mitochondrial protein OM64 influences protein import into mitochondria. Mitochondrion, 44, 2019
6QEC	DNA binding domain of LUX ARRYTHMO in complex with DNA 分子名称: DNA (5'-D(*AP*TP*TP*CP*GP*AP*AP*TP*AP*T*TP*AP*TP*AP*TP*TP*CP*GP*AP*A)-3'), GLYCEROL, Transcription factor LUX 著者 Zubieta, C, Nayak, A. 登録日 2019-01-07 公開日 2020-02-05 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Molecular mechanisms of Evening Complex activity inArabidopsis. Proc.Natl.Acad.Sci.USA, 117, 2020
6QPL	Crystal structure of Spindlin1 in complex with the inhibitor MS31 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Johansson, C, Krojer, T, Xiong, Y, Jin, J, Arrowsmith, C.H, Bountra, C, Edwards, A, Oppermann, U.C.T. 登録日 2019-02-14 公開日 2019-07-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Discovery of a Potent and Selective Fragment-like Inhibitor of Methyllysine Reader Protein Spindlin 1 (SPIN1). J.Med.Chem., 62, 2019
4IKC	Crystal Structure of catalytic domain of PTPRQ 分子名称: CHLORIDE ION, Phosphotidylinositol phosphatase PTPRQ, SULFATE ION 著者 Yu, K.R, Ryu, S.E, Kim, S.J. 登録日 2012-12-26 公開日 2013-07-31 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Structural basis for the dephosphorylating activity of PTPRQ towards phosphatidylinositide substrates Acta Crystallogr.,Sect.D, 69, 2013

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