1NEE
| Structure of archaeal translation factor aIF2beta from Methanobacterium thermoautrophicum | 分子名称: | Probable translation initiation factor 2 beta subunit, ZINC ION | 著者 | Gutierrez, P, Trempe, J.F, Siddiqui, N, Arrowsmith, C, Gehring, K. | 登録日 | 2002-12-11 | 公開日 | 2004-03-09 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the archaeal translation initiation factor aIF2beta from Methanobacterium thermoautotrophicum: Implications for translation initiation. Protein Sci., 13, 2004
|
|
1Z8G
| Crystal structure of the extracellular region of the transmembrane serine protease hepsin with covalently bound preferred substrate. | 分子名称: | ACE-LYS-GLN-LEU-ARG-Chloromethylketone, Serine protease hepsin | 著者 | Herter, S, Piper, D.E, Aaron, W, Gabriele, T, Cutler, G, Cao, P, Bhatt, A.S, Choe, Y, Craik, C.S, Walker, N, Meininger, D, Hoey, T, Austin, R.J. | 登録日 | 2005-03-30 | 公開日 | 2005-05-03 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers Biochem.J., 390, 2005
|
|
1DPI
| |
1EHX
| NMR SOLUTION STRUCTURE OF THE LAST UNKNOWN MODULE OF THE CELLULOSOMAL SCAFFOLDIN PROTEIN CIPC OF CLOSTRIDUM CELLULOLYTICUM | 分子名称: | SCAFFOLDIN PROTEIN | 著者 | Mosbah, A, Belaich, A, Bornet, O, Belaich, J.P, Henrissat, B, Darbon, H. | 登録日 | 2000-02-23 | 公開日 | 2000-11-17 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the module X2 1 of unknown function of the cellulosomal scaffolding protein CipC of Clostridium cellulolyticum. J.Mol.Biol., 304, 2000
|
|
2BGN
| HIV-1 Tat protein derived N-terminal nonapeptide Trp2-Tat(1-9) bound to the active site of Dipeptidyl peptidase IV (CD26) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Weihofen, W.A, Liu, J, Reutter, W, Saenger, W, Fan, H. | 登録日 | 2005-01-03 | 公開日 | 2005-01-27 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Crystal Structures of HIV-1 Tat-Derived Nonapeptides Tat-(1-9) and Trp2-Tat-(1-9) Bound to the Active Site of Dipeptidyl-Peptidase Iv (Cd26) J.Biol.Chem., 280, 2005
|
|
3QHW
| Structure of a pCDK2/CyclinA transition-state mimic | 分子名称: | (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, ADENOSINE-5'-DIPHOSPHATE, CDK2 substrate peptide: PKTPKKAKKL, ... | 著者 | Young, M.A, Jacobsen, D.M, Bao, Z.Q. | 登録日 | 2011-01-26 | 公開日 | 2011-05-25 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Briefly Bound to Activate: Transient Binding of a Second Catalytic Magnesium Activates the Structure and Dynamics of CDK2 Kinase for Catalysis. Structure, 19, 2011
|
|
8PNT
| Structure of the human nuclear cap-binding complex bound to PHAX and m7G-capped RNA | 分子名称: | 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, ... | 著者 | Dubiez, E, Pellegrini, E, Foucher, A.E, Cusack, S, Kadlec, J. | 登録日 | 2023-07-01 | 公開日 | 2024-01-17 | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | 主引用文献 | Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex. Cell Rep, 43, 2024
|
|
8PMP
| Structure of the human nuclear cap-binding complex bound to ARS2[147-871] and m7GTP | 分子名称: | 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, ... | 著者 | Dubiez, E, Pellegrini, E, Foucher, A.E, Cusack, S, Kadlec, J. | 登録日 | 2023-06-29 | 公開日 | 2024-01-17 | 実験手法 | ELECTRON MICROSCOPY (3.43 Å) | 主引用文献 | Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex. Cell Rep, 43, 2024
|
|
1OXK
| |
1WQJ
| Structural Basis for the Regulation of Insulin-Like Growth Factors (IGFs) by IGF Binding Proteins (IGFBPs) | 分子名称: | Insulin-like growth factor IB, Insulin-like growth factor binding protein 4 | 著者 | Siwanowicz, I, Popowicz, G.M, Wisniewska, M, Huber, R, Kuenkele, K.P, Lang, K, Engh, R.A, Holak, T.A. | 登録日 | 2004-09-29 | 公開日 | 2005-03-01 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural basis for the regulation of insulin-like growth factors by IGF binding proteins Structure, 13, 2005
|
|
2CY3
| |
4DYZ
| |
4H76
| Crystal structure of the catalytic domain of Human MMP12 in complex with a broad spectrum hydroxamate inhibitor | 分子名称: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Stura, E.A, Vera, L, Cassar-Lajeunesse, E, Nuti, E, Dive, V, Rossello, A. | 登録日 | 2012-09-20 | 公開日 | 2013-04-24 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystallization of bi-functional ligand protein complexes. J.Struct.Biol., 182, 2013
|
|
3T82
| |
1PBE
| |
4DZ0
| |
1PEG
| Structural basis for the product specificity of histone lysine methyltransferases | 分子名称: | Histone H3, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ... | 著者 | Zhang, X, Yang, Z, Khan, S.I, Horton, J.R, Tamaru, H, Selker, E.U, Cheng, X. | 登録日 | 2003-05-21 | 公開日 | 2003-08-05 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Structural basis for the product specificity of histone lysine methyltransferases Mol.Cell, 12, 2003
|
|
4HIF
| Ultrahigh-resolution crystal structure of Z-DNA in complex with Zn2+ ions | 分子名称: | CHLORIDE ION, DNA (5'-D(*CP*GP*CP*GP*CP*G)-3'), SPERMINE (FULLY PROTONATED FORM), ... | 著者 | Drozdzal, P, Gilski, M, Kierzek, R, Lomozik, L, Jaskolski, M. | 登録日 | 2012-10-11 | 公開日 | 2013-06-05 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (0.85 Å) | 主引用文献 | Ultrahigh-resolution crystal structures of Z-DNA in complex with Mn(2+) and Zn(2+) ions. Acta Crystallogr.,Sect.D, 69, 2013
|
|
4E5Z
| |
1WER
| RAS-GTPASE-ACTIVATING DOMAIN OF HUMAN P120GAP | 分子名称: | P120GAP | 著者 | Scheffzek, K, Lautwein, A, Kabsch, W, Ahmadian, M.R, Wittinghofer, A. | 登録日 | 1996-11-20 | 公開日 | 1997-12-31 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure of the GTPase-activating domain of human p120GAP and implications for the interaction with Ras. Nature, 384, 1996
|
|
1PHP
| |
5IWG
| HDAC2 WITH LIGAND BRD4884 | 分子名称: | 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Steinbacher, S. | 登録日 | 2016-03-22 | 公開日 | 2016-08-31 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Kinetic and structural insights into the binding of histone deacetylase 1 and 2 (HDAC1, 2) inhibitors. Bioorg.Med.Chem., 24, 2016
|
|
1PJU
| Unbound form of Tomato Inhibitor-II | 分子名称: | SULFATE ION, Wound-induced proteinase inhibitor II | 著者 | Barrette-Ng, I.H, Ng, K.K.-S, Cherney, M.M, Pearce, G, Ghani, U, Ryan, C.A, James, M.N.G. | 登録日 | 2003-06-03 | 公開日 | 2003-09-16 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Unbound form of tomato inhibitor-II reveals interdomain flexibility and conformational variability in the reactive site loops J.Biol.Chem., 278, 2003
|
|
1PLC
| |
5IX0
| HDAC2 WITH LIGAND BRD7232 | 分子名称: | (3-exo)-N-(4-amino-4'-fluoro[1,1'-biphenyl]-3-yl)-8-oxabicyclo[3.2.1]octane-3-carboxamide, 1,2-ETHANEDIOL, 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, ... | 著者 | Steinbacher, S. | 登録日 | 2016-03-23 | 公開日 | 2016-08-31 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Kinetic and structural insights into the binding of histone deacetylase 1 and 2 (HDAC1, 2) inhibitors. Bioorg.Med.Chem., 24, 2016
|
|