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1NEE
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BU of 1nee by Molmil
Structure of archaeal translation factor aIF2beta from Methanobacterium thermoautrophicum
分子名称: Probable translation initiation factor 2 beta subunit, ZINC ION
著者Gutierrez, P, Trempe, J.F, Siddiqui, N, Arrowsmith, C, Gehring, K.
登録日2002-12-11
公開日2004-03-09
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of the archaeal translation initiation factor aIF2beta from Methanobacterium thermoautotrophicum: Implications for translation initiation.
Protein Sci., 13, 2004
1Z8G
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BU of 1z8g by Molmil
Crystal structure of the extracellular region of the transmembrane serine protease hepsin with covalently bound preferred substrate.
分子名称: ACE-LYS-GLN-LEU-ARG-Chloromethylketone, Serine protease hepsin
著者Herter, S, Piper, D.E, Aaron, W, Gabriele, T, Cutler, G, Cao, P, Bhatt, A.S, Choe, Y, Craik, C.S, Walker, N, Meininger, D, Hoey, T, Austin, R.J.
登録日2005-03-30
公開日2005-05-03
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers
Biochem.J., 390, 2005
1DPI
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BU of 1dpi by Molmil
STRUCTURE OF LARGE FRAGMENT OF ESCHERICHIA COLI DNA POLYMERASE I COMPLEXED WITH D/TMP
分子名称: DNA POLYMERASE I KLENOW FRAGMENT, ZINC ION
著者Beese, L, Ollis, D, Steitz, T.
登録日1987-08-11
公開日1987-10-16
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMP.
Nature, 313, 1985
1EHX
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BU of 1ehx by Molmil
NMR SOLUTION STRUCTURE OF THE LAST UNKNOWN MODULE OF THE CELLULOSOMAL SCAFFOLDIN PROTEIN CIPC OF CLOSTRIDUM CELLULOLYTICUM
分子名称: SCAFFOLDIN PROTEIN
著者Mosbah, A, Belaich, A, Bornet, O, Belaich, J.P, Henrissat, B, Darbon, H.
登録日2000-02-23
公開日2000-11-17
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the module X2 1 of unknown function of the cellulosomal scaffolding protein CipC of Clostridium cellulolyticum.
J.Mol.Biol., 304, 2000
2BGN
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BU of 2bgn by Molmil
HIV-1 Tat protein derived N-terminal nonapeptide Trp2-Tat(1-9) bound to the active site of Dipeptidyl peptidase IV (CD26)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Weihofen, W.A, Liu, J, Reutter, W, Saenger, W, Fan, H.
登録日2005-01-03
公開日2005-01-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Crystal Structures of HIV-1 Tat-Derived Nonapeptides Tat-(1-9) and Trp2-Tat-(1-9) Bound to the Active Site of Dipeptidyl-Peptidase Iv (Cd26)
J.Biol.Chem., 280, 2005
3QHW
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BU of 3qhw by Molmil
Structure of a pCDK2/CyclinA transition-state mimic
分子名称: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, ADENOSINE-5'-DIPHOSPHATE, CDK2 substrate peptide: PKTPKKAKKL, ...
著者Young, M.A, Jacobsen, D.M, Bao, Z.Q.
登録日2011-01-26
公開日2011-05-25
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Briefly Bound to Activate: Transient Binding of a Second Catalytic Magnesium Activates the Structure and Dynamics of CDK2 Kinase for Catalysis.
Structure, 19, 2011
8PNT
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BU of 8pnt by Molmil
Structure of the human nuclear cap-binding complex bound to PHAX and m7G-capped RNA
分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, ...
著者Dubiez, E, Pellegrini, E, Foucher, A.E, Cusack, S, Kadlec, J.
登録日2023-07-01
公開日2024-01-17
実験手法ELECTRON MICROSCOPY (3.46 Å)
主引用文献Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex.
Cell Rep, 43, 2024
8PMP
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BU of 8pmp by Molmil
Structure of the human nuclear cap-binding complex bound to ARS2[147-871] and m7GTP
分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, ...
著者Dubiez, E, Pellegrini, E, Foucher, A.E, Cusack, S, Kadlec, J.
登録日2023-06-29
公開日2024-01-17
実験手法ELECTRON MICROSCOPY (3.43 Å)
主引用文献Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex.
Cell Rep, 43, 2024
1OXK
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BU of 1oxk by Molmil
Complex between YPD1 and SLN1 response regulator domain in space group P3(2)
分子名称: SLN1, SULFATE ION, Ypd1p
著者Xu, Q, Porter, S.W, West, A.H.
登録日2003-04-02
公開日2003-12-16
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Yeast YPD1/SLN1 Complex. Insights into Molecular Recognition in Two-Component Signaling Systems.
Structure, 11, 2003
1WQJ
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BU of 1wqj by Molmil
Structural Basis for the Regulation of Insulin-Like Growth Factors (IGFs) by IGF Binding Proteins (IGFBPs)
分子名称: Insulin-like growth factor IB, Insulin-like growth factor binding protein 4
著者Siwanowicz, I, Popowicz, G.M, Wisniewska, M, Huber, R, Kuenkele, K.P, Lang, K, Engh, R.A, Holak, T.A.
登録日2004-09-29
公開日2005-03-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis for the regulation of insulin-like growth factors by IGF binding proteins
Structure, 13, 2005
2CY3
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BU of 2cy3 by Molmil
CRYSTAL STRUCTURE OF CYTOCHROME C3 FROM DESULFOVIBRIO DESULFURICANS NORWAY AT 1.7 ANGSTROMS RESOLUTION
分子名称: CYTOCHROME C3, HEME C
著者Czjzek, M, Payan, F, Haser, R.
登録日1994-07-01
公開日1994-10-15
最終更新日2021-03-03
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of cytochrome c3 from Desulfovibrio desulfuricans Norway at 1.7 A resolution.
J.Mol.Biol., 243, 1994
4DYZ
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BU of 4dyz by Molmil
Crystal Structure of the apo form of Human H-Ferritin variant MIC1
分子名称: CALCIUM ION, COPPER (II) ION, Ferritin heavy chain
著者Tezcan, F.A, Huard, D.J.E.
登録日2012-02-29
公開日2013-01-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Re-engineering protein interfaces yields copper-inducible ferritin cage assembly.
Nat.Chem.Biol., 9, 2013
4H76
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BU of 4h76 by Molmil
Crystal structure of the catalytic domain of Human MMP12 in complex with a broad spectrum hydroxamate inhibitor
分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Stura, E.A, Vera, L, Cassar-Lajeunesse, E, Nuti, E, Dive, V, Rossello, A.
登録日2012-09-20
公開日2013-04-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystallization of bi-functional ligand protein complexes.
J.Struct.Biol., 182, 2013
3T82
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BU of 3t82 by Molmil
Human Carbonic Anhydrase II in complex with Acetylated Carbohydrate Sulfamates
分子名称: 3,4-di-O-acetyl-6-O-sulfamoyl-alpha-D-glucopyranose, Carbonic anhydrase 2, ZINC ION
著者Hofmann, A, Wang, C.K.
登録日2011-08-01
公開日2011-10-19
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.002 Å)
主引用文献Promiscuity of carbonic anhydrase II. Unexpected ester hydrolysis of carbohydrate-based sulfamate inhibitors.
J.Am.Chem.Soc., 133, 2011
1PBE
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BU of 1pbe by Molmil
CRYSTAL STRUCTURE OF THE P-HYDROXYBENZOATE HYDROXYLASE-SUBSTRATE COMPLEX REFINED AT 1.9 ANGSTROMS RESOLUTION. ANALYSIS OF THE ENZYME-SUBSTRATE AND ENZYME-PRODUCT COMPLEXES
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOATE HYDROXYLASE, P-HYDROXYBENZOIC ACID
著者Schreuder, H.A, Hol, W.G.J, Drenth, J.
登録日1994-07-06
公開日1994-09-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the p-hydroxybenzoate hydroxylase-substrate complex refined at 1.9 A resolution. Analysis of the enzyme-substrate and enzyme-product complexes.
J.Mol.Biol., 208, 1989
4DZ0
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BU of 4dz0 by Molmil
Crystal structure of the Cu-adduct of human H-Ferritin variant MIC1 labeled with a dansyl fluorophore
分子名称: 5-(1-SULFONAPHTHYL)-ACETYLAMINO-ETHYLAMINE, CALCIUM ION, COPPER (II) ION, ...
著者Tezcan, F.A, Huard, D.J.E.
登録日2012-02-29
公開日2013-01-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Re-engineering protein interfaces yields copper-inducible ferritin cage assembly.
Nat.Chem.Biol., 9, 2013
1PEG
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BU of 1peg by Molmil
Structural basis for the product specificity of histone lysine methyltransferases
分子名称: Histone H3, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ...
著者Zhang, X, Yang, Z, Khan, S.I, Horton, J.R, Tamaru, H, Selker, E.U, Cheng, X.
登録日2003-05-21
公開日2003-08-05
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Structural basis for the product specificity of histone lysine methyltransferases
Mol.Cell, 12, 2003
4HIF
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BU of 4hif by Molmil
Ultrahigh-resolution crystal structure of Z-DNA in complex with Zn2+ ions
分子名称: CHLORIDE ION, DNA (5'-D(*CP*GP*CP*GP*CP*G)-3'), SPERMINE (FULLY PROTONATED FORM), ...
著者Drozdzal, P, Gilski, M, Kierzek, R, Lomozik, L, Jaskolski, M.
登録日2012-10-11
公開日2013-06-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (0.85 Å)
主引用文献Ultrahigh-resolution crystal structures of Z-DNA in complex with Mn(2+) and Zn(2+) ions.
Acta Crystallogr.,Sect.D, 69, 2013
4E5Z
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BU of 4e5z by Molmil
Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair
分子名称: AP24 DNA complementary strand, AP24 DNA strand, DNA damage-binding protein 1, ...
著者Yeh, J.I, Du, S.
登録日2012-03-15
公開日2012-08-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair.
Proc.Natl.Acad.Sci.USA, 109, 2012
1WER
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BU of 1wer by Molmil
RAS-GTPASE-ACTIVATING DOMAIN OF HUMAN P120GAP
分子名称: P120GAP
著者Scheffzek, K, Lautwein, A, Kabsch, W, Ahmadian, M.R, Wittinghofer, A.
登録日1996-11-20
公開日1997-12-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of the GTPase-activating domain of human p120GAP and implications for the interaction with Ras.
Nature, 384, 1996
1PHP
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BU of 1php by Molmil
STRUCTURE OF THE ADP COMPLEX OF THE 3-PHOSPHOGLYCERATE KINASE FROM BACILLUS STEAROTHERMOPHILUS AT 1.65 ANGSTROMS
分子名称: 3-PHOSPHOGLYCERATE KINASE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Davies, G.J, Watson, H.C.
登録日1994-04-12
公開日1994-06-22
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure of the ADP complex of the 3-phosphoglycerate kinase from Bacillus stearothermophilus at 1.65 A.
Acta Crystallogr.,Sect.D, 50, 1994
5IWG
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BU of 5iwg by Molmil
HDAC2 WITH LIGAND BRD4884
分子名称: 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
著者Steinbacher, S.
登録日2016-03-22
公開日2016-08-31
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Kinetic and structural insights into the binding of histone deacetylase 1 and 2 (HDAC1, 2) inhibitors.
Bioorg.Med.Chem., 24, 2016
1PJU
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BU of 1pju by Molmil
Unbound form of Tomato Inhibitor-II
分子名称: SULFATE ION, Wound-induced proteinase inhibitor II
著者Barrette-Ng, I.H, Ng, K.K.-S, Cherney, M.M, Pearce, G, Ghani, U, Ryan, C.A, James, M.N.G.
登録日2003-06-03
公開日2003-09-16
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Unbound form of tomato inhibitor-II reveals interdomain flexibility and conformational variability in the reactive site loops
J.Biol.Chem., 278, 2003
1PLC
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BU of 1plc by Molmil
ACCURACY AND PRECISION IN PROTEIN CRYSTAL STRUCTURE ANALYSIS: RESTRAINED LEAST-SQUARES REFINEMENT OF THE CRYSTAL STRUCTURE OF POPLAR PLASTOCYANIN AT 1.33 ANGSTROMS RESOLUTION
分子名称: COPPER (II) ION, PLASTOCYANIN
著者Guss, J.M, Freeman, H.C.
登録日1992-03-11
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献Accuracy and precision in protein structure analysis: restrained least-squares refinement of the structure of poplar plastocyanin at 1.33 A resolution.
Acta Crystallogr.,Sect.B, 48, 1992
5IX0
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HDAC2 WITH LIGAND BRD7232
分子名称: (3-exo)-N-(4-amino-4'-fluoro[1,1'-biphenyl]-3-yl)-8-oxabicyclo[3.2.1]octane-3-carboxamide, 1,2-ETHANEDIOL, 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, ...
著者Steinbacher, S.
登録日2016-03-23
公開日2016-08-31
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Kinetic and structural insights into the binding of histone deacetylase 1 and 2 (HDAC1, 2) inhibitors.
Bioorg.Med.Chem., 24, 2016

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