Summary for 1Z8G
| Related PRD ID | PRD_000307 |
|---|---|
| Descriptor | Serine protease hepsin, ACE-LYS-GLN-LEU-ARG-Chloromethylketone (3 entities in total) |
| Functional Keywords | serine protease hepsin, protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Homo sapiens (human) More |
| Cellular location | Membrane; Single-pass type II membrane protein P05981 |
| Total number of polymer chains | 2 |
| Total molecular weight | 41054.97 |
| Authors | Herter, S.,Piper, D.E.,Aaron, W.,Gabriele, T.,Cutler, G.,Cao, P.,Bhatt, A.S.,Choe, Y.,Craik, C.S.,Walker, N.,Meininger, D.,Hoey, T.,Austin, R.J. (deposition date: 2005-03-30, release date: 2005-05-03, Last modification date: 2012-12-12) |
| Primary citation | Herter, S.,Piper, D.E.,Aaron, W.,Gabriele, T.,Cutler, G.,Cao, P.,Bhatt, A.S.,Choe, Y.,Craik, C.S.,Walker, N.,Meininger, D.,Hoey, T.,Austin, R.J. Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers Biochem.J., 390:125-136, 2005 PubMed: 15839837 (PDB entries with the same primary citation) DOI: 10.1042/BJ20041955  Import into Mendeley |
| Experimental method | X-RAY DIFFRACTION (1.55 Å) |
