Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0016020 | cellular_component | membrane |
| A | 0070008 | molecular_function | serine-type exopeptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR CHAIN L OF ACE-LYS-GLN-LEU-ARG-CHLOROMETHYLKETONE |
| Chain | Residue |
| A | HIS203 |
| A | GLN350 |
| A | GLY351 |
| A | SER353 |
| A | SER376 |
| A | TRP377 |
| A | GLY378 |
| A | THR379 |
| A | GLY380 |
| A | CYS381 |
| A | GLY388 |
| A | TYR243 |
| A | HOH476 |
| A | HOH524 |
| L | HOH188 |
| L | HOH267 |
| L | HOH268 |
| L | HOH302 |
| L | HOH409 |
| A | GLU252 |
| A | ASN254 |
| A | TYR301 |
| A | GLN331 |
| A | ASP347 |
| A | ALA348 |
| A | CYS349 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
| Chain | Residue | Details |
| A | LEU199-CYS204 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DAcqGDSGGPFV |
| Chain | Residue | Details |
| A | ASP347-VAL358 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 97 |
| Details | Domain: {"description":"SRCR"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 242 |
| Details | Domain: {"description":"Peptidase S1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00274","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"source":"PubMed","id":"12962630","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"15839837","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | ASP257 | |
| A | HIS203 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | SER353 | |
| A | GLY354 | |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | SER353 | |
| A | GLY351 | |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | SER353 | |
| A | ASP257 | |
| A | HIS203 | |
| site_id | CSA5 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | SER353 | |
| A | GLY354 | |
| A | ASP257 | |
| A | HIS203 | |
| site_id | CSA6 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | SER353 | |
| A | ASP257 | |
| A | SER376 | |
| A | GLY351 | |
| A | HIS203 | |
| site_id | CSA7 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | SER353 | |
| A | ASP257 | |
| A | GLY351 | |
| A | HIS203 | |
1Z8G
