5IWG
HDAC2 WITH LIGAND BRD4884
Summary for 5IWG
Entry DOI | 10.2210/pdb5iwg/pdb |
Related | 5IX0 |
Descriptor | Histone deacetylase 2, ZINC ION, CALCIUM ION, ... (9 entities in total) |
Functional Keywords | hdac histone deacetylase, hydrolase |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus : Q92769 |
Total number of polymer chains | 3 |
Total formula weight | 129270.42 |
Authors | Steinbacher, S. (deposition date: 2016-03-22, release date: 2016-08-31, Last modification date: 2024-03-06) |
Primary citation | Wagner, F.F.,Weiwer, M.,Steinbacher, S.,Schomburg, A.,Reinemer, P.,Gale, J.P.,Campbell, A.J.,Fisher, S.L.,Zhao, W.N.,Reis, S.A.,Hennig, K.M.,Thomas, M.,Muller, P.,Jefson, M.R.,Fass, D.M.,Haggarty, S.J.,Zhang, Y.L.,Holson, E.B. Kinetic and structural insights into the binding of histone deacetylase 1 and 2 (HDAC1, 2) inhibitors. Bioorg.Med.Chem., 24:4008-4015, 2016 Cited by PubMed: 27377864DOI: 10.1016/j.bmc.2016.06.040 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.66 Å) |
Structure validation
Download full validation report