5L3Z
 
 | | polyketide ketoreductase SimC7 - binary complex with NADP+ | | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, polyketide ketoreductase SimC7 | | 著者 | Schafer, M, Stevenson, C.E.M, Wilkinson, B, Lawson, D.M, Buttner, M.J. | | 登録日 | 2016-05-24 | | 公開日 | 2016-10-05 | | 最終更新日 | 2017-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Substrate-Assisted Catalysis in Polyketide Reduction Proceeds via a Phenolate Intermediate.
Cell Chem Biol, 23, 2016
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4CZ1
 | | Crystal structure of kynurenine formamidase from Bacillus anthracis complexed with 2-aminoacetophenone. | | 分子名称: | 2-aminoacetophenone, KYNURENINE FORMAMIDASE, MAGNESIUM ION, ... | | 著者 | Diaz-Saez, L, Srikannathasan, V, Zoltner, M, Hunter, W.N. | | 登録日 | 2014-04-16 | | 公開日 | 2014-04-30 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | Structure of Bacterial Kynurenine Formamidase Reveals a Crowded Binuclear-Zinc Catalytic Site Primed to Generate a Potent Nucleophile.
Biochem.J., 462, 2014
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1D7Y
 | | CRYSTAL STRUCTURE OF NADH-DEPENDENT FERREDOXIN REDUCTASE, BPHA4 | | 分子名称: | FERREDOXIN REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE | | 著者 | Senda, T, Yamada, T, Sakurai, N, Kubota, M, Nishizaki, T, Masai, E, Fukuda, M, Mitsui, Y. | | 登録日 | 1999-10-21 | | 公開日 | 2000-12-20 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of NADH-dependent ferredoxin reductase component in biphenyl dioxygenase.
J.Mol.Biol., 304, 2000
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1D8L
 | | E. COLI HOLLIDAY JUNCTION BINDING PROTEIN RUVA NH2 REGION LACKING DOMAIN III | | 分子名称: | PROTEIN (HOLLIDAY JUNCTION DNA HELICASE RUVA) | | 著者 | Nishino, T, Iwasaki, H, Kataoka, M, Ariyoshi, M, Fujita, T, Shinagawa, H, Morikawa, K. | | 登録日 | 1999-10-25 | | 公開日 | 2000-05-03 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Modulation of RuvB function by the mobile domain III of the Holliday junction recognition protein RuvA.
J.Mol.Biol., 298, 2000
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7W44
 | | Complex structure of a leaf-branch compost cutinase variant LCC ICCG_RIP | | 分子名称: | 1,2-ETHANEDIOL, IMIDAZOLE, Leaf-branch compost cutinase | | 著者 | Niu, D, Zeng, W, Huang, J.W, Chen, C.C, Liu, W.D, Guo, R.T. | | 登録日 | 2021-11-26 | | 公開日 | 2022-03-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Substrate-Binding Mode of a Thermophilic PET Hydrolase and Engineering the Enzyme to Enhance the Hydrolytic Efficacy.
Acs Catalysis, 12, 2022
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8HUD
 | | Cryo-EM structure of the EvCas9-sgRNA-target DNA ternary complex | | 分子名称: | CRISPR-associated endonuclease Cas9, Non-target DNA strand, Target DNA strand, ... | | 著者 | Tang, N, Wu, Z, Gao, Y, Chen, W, Su, M, Wang, Z, Ji, Q. | | 登録日 | 2022-12-23 | | 公開日 | 2023-12-27 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (3.43 Å) | | 主引用文献 | Molecular Basis and Genome Editing Applications of a Compact Eubacterium ventriosum CRISPR-Cas9 System.
Acs Synth Biol, 13, 2024
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7W45
 | | Complex structure of a leaf-branch compost cutinase variant LCC ICCG_KIP | | 分子名称: | CALCIUM ION, Leaf-branch compost cutinase, SODIUM ION | | 著者 | Niu, D, Zeng, W, Huang, J.W, Chen, C.C, Liu, W.D, Guo, R.T. | | 登録日 | 2021-11-26 | | 公開日 | 2022-03-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Substrate-Binding Mode of a Thermophilic PET Hydrolase and Engineering the Enzyme to Enhance the Hydrolytic Efficacy.
Acs Catalysis, 12, 2022
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7W1N
 | | Complex structure of a leaf-branch compost cutinase variant LCC ICCG_KRP | | 分子名称: | 1,2-ETHANEDIOL, BICINE, Leaf-branch compost cutinase | | 著者 | Niu, D, Zeng, W, Huang, J.W, Chen, C.C, Liu, W.D, Guo, R.T. | | 登録日 | 2021-11-19 | | 公開日 | 2022-03-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Substrate-Binding Mode of a Thermophilic PET Hydrolase and Engineering the Enzyme to Enhance the Hydrolytic Efficacy.
Acs Catalysis, 12, 2022
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1CXC
 | | CRYSTALLIZATION AND X-RAY STRUCTURE DETERMINATION OF CYTOCHROME C2 FROM RHODOBACTER SPHAEROIDES IN THREE CRYSTAL FORMS | | 分子名称: | CYTOCHROME C2, HEME C | | 著者 | Axelrod, H.L, Feher, G, Allen, J.P, Chirino, A.J, Day, M.W, Hsu, B.T, Rees, D.C. | | 登録日 | 1994-02-14 | | 公開日 | 1995-09-15 | | 最終更新日 | 2021-03-03 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystallization and X-ray structure determination of cytochrome c2 from Rhodobacter sphaeroides in three crystal forms.
Acta Crystallogr.,Sect.D, 50, 1994
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7WB1
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7WAY
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1D2E
 | | CRYSTAL STRUCTURE OF MITOCHONDRIAL EF-TU IN COMPLEX WITH GDP | | 分子名称: | ELONGATION FACTOR TU (EF-TU), GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | 著者 | Andersen, G.R, Thirup, S, Spremulli, L.L, Nyborg, J. | | 登録日 | 1999-09-23 | | 公開日 | 1999-09-28 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | High resolution crystal structure of bovine mitochondrial EF-Tu in complex with GDP.
J.Mol.Biol., 297, 2000
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1D7H
 | | FKBP COMPLEXED WITH DMSO | | 分子名称: | AMMONIUM ION, DIMETHYL SULFOXIDE, PROTEIN (FK506-BINDING PROTEIN), ... | | 著者 | Burkhard, P, Taylor, P, Walkinshaw, M.D. | | 登録日 | 1999-10-18 | | 公開日 | 1999-10-21 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | X-ray structures of small ligand-FKBP complexes provide an estimate for hydrophobic interaction energies.
J.Mol.Biol., 295, 2000
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6UAN
 | | B-Raf:14-3-3 complex | | 分子名称: | 14-3-3 zeta, Serine/threonine-protein kinase B-raf | | 著者 | Kondo, Y, Ognjenovic, J, Banerjee, S, Karandur, D, Merk, A, Kulhanek, K, Wong, K, Roose, J.P, Subramaniam, S, Kuriyan, J. | | 登録日 | 2019-09-11 | | 公開日 | 2019-09-25 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Cryo-EM structure of a dimeric B-Raf:14-3-3 complex reveals asymmetry in the active sites of B-Raf kinases.
Science, 366, 2019
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5LOJ
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5LP9
 | | FimA wt from S. flexneri | | 分子名称: | Major type 1 subunit fimbrin (Pilin) | | 著者 | Zyla, D, Capitani, G, Prota, A, Glockshuber, R. | | 登録日 | 2016-08-12 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (0.88626635 Å) | | 主引用文献 | Alternative folding to a monomer or homopolymer is a common feature of the type 1 pilus subunit FimA from enteroinvasive bacteria.
J.Biol.Chem., 2019
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5LOE
 | | Structure of full length Cody from Bacillus subtilis in complex with Ile | | 分子名称: | GTP-sensing transcriptional pleiotropic repressor CodY, ISOLEUCINE | | 著者 | Wilkinson, A.J, Levdikov, V.M, Blagova, E.V. | | 登録日 | 2016-08-09 | | 公開日 | 2017-01-11 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure of the Branched-chain Amino Acid and GTP-sensing Global Regulator, CodY, from Bacillus subtilis.
J. Biol. Chem., 292, 2017
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5SZT
 | | Crystal structure of the large fragment of DNA Polymerase I from Thermus aquaticus in a closed ternary complex with 7-(N-(10-hydroxydecanoyl)-aminopentenyl)-7-deaza-2'-dATP | | 分子名称: | 7-(N-(10-hydroxydecanoyl)-aminopentenyl)-7-deaza-2'-dATP, ACETATE ION, DNA (5'-D(*AP*AP*AP*TP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... | | 著者 | Hottin, A, Betz, K, Marx, A. | | 登録日 | 2016-08-15 | | 公開日 | 2016-12-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural Basis for the KlenTaq DNA Polymerase Catalysed Incorporation of Alkene- versus Alkyne-Modified Nucleotides.
Chemistry, 23, 2017
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1CXN
 | | REFINED THREE-DIMENSIONAL SOLUTION STRUCTURE OF A SNAKE CARDIOTOXIN: ANALYSIS OF THE SIDE-CHAIN ORGANISATION SUGGESTS THE EXISTENCE OF A POSSIBLE PHOSPHOLIPID BINDING SITE | | 分子名称: | CARDIOTOXIN GAMMA | | 著者 | Gilquin, B, Roumestand, C, Zinn-Justin, S, Menez, A, Toma, F. | | 登録日 | 1994-07-08 | | 公開日 | 1994-12-20 | | 最終更新日 | 2022-02-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Refined three-dimensional solution structure of a snake cardiotoxin: analysis of the side-chain organization suggests the existence of a possible phospholipid binding site.
Biopolymers, 33, 1993
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2IKG
 | | Aldose reductase complexed with nitrophenyl-oxadiazol type inhibitor at 1.43 A | | 分子名称: | 4-[3-(3-NITROPHENYL)-1,2,4-OXADIAZOL-5-YL]BUTANOIC ACID, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Steuber, H, Koch, C, Heine, A, Klebe, G. | | 登録日 | 2006-10-02 | | 公開日 | 2007-05-01 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | Structural and Thermodynamic Study on Aldose Reductase: Nitro-substituted Inhibitors with Strong Enthalpic Binding Contribution
J.Mol.Biol., 368, 2007
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4XQW
 | | X-ray structure analysis of xylanase-N44E with MES at pH6.0 | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Endo-1,4-beta-xylanase 2, IODIDE ION | | 著者 | Wan, Q, Park, J.M, Riccardi, D.M, Hanson, L.B, Fisher, Z, Smith, J.C, Ostermann, A, Schrader, T, Graham, D.E, Coates, L, Langan, P, Kovalevsky, A.Y. | | 登録日 | 2015-01-20 | | 公開日 | 2015-09-23 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Direct determination of protonation states and visualization of hydrogen bonding in a glycoside hydrolase with neutron crystallography.
Proc.Natl.Acad.Sci.USA, 112, 2015
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1GBU
 | | DEOXY (BETA-(C93A,C112G)) HUMAN HEMOGLOBIN | | 分子名称: | HEMOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | | 著者 | Vasquez, G.B, Ji, X, Fronticelli, C, Gilliland, G.L. | | 登録日 | 1996-01-04 | | 公開日 | 1997-01-11 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Cysteines beta93 and beta112 as probes of conformational and functional events at the human hemoglobin subunit interfaces.
Biophys.J., 76, 1999
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1CQX
 | | Crystal structure of the flavohemoglobin from Alcaligenes eutrophus at 1.75 A resolution | | 分子名称: | 1-[GLYCEROLYLPHOSPHONYL]-2-[8-(2-HEXYL-CYCLOPROPYL)-OCTANAL-1-YL]-3-[HEXADECANAL-1-YL]-GLYCEROL, FLAVIN-ADENINE DINUCLEOTIDE, FLAVOHEMOPROTEIN, ... | | 著者 | Ermler, U, Siddiqui, R.A, Cramm, R, Friedrich, B. | | 登録日 | 1999-08-12 | | 公開日 | 1999-08-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal structure of the flavohemoglobin from Alcaligenes eutrophus at 1.75 A resolution.
EMBO J., 14, 1995
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1CQL
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4EJ7
 | | Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, ATP-bound | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Aminoglycoside 3'-phosphotransferase AphA1-IAB, CALCIUM ION, ... | | 著者 | Stogios, P.J, Minasov, G, Tan, K, Evdokimova, E, Egorova, O, Di Leo, R, Shakya, T, Wright, G.D, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2012-04-06 | | 公開日 | 2012-04-18 | | 最終更新日 | 2013-09-04 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Structure-guided optimization of protein kinase inhibitors reverses aminoglycoside antibiotic resistance.
Biochem.J., 454, 2013
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