Summary for 4EJ7
| Entry DOI | 10.2210/pdb4ej7/pdb |
| Related | 4FEU 4FEV 4FEW 4FEX 4GKH 4GKI |
| Descriptor | Aminoglycoside 3'-phosphotransferase AphA1-IAB, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ... (5 entities in total) |
| Functional Keywords | center for structural genomics of infectious diseases, csgid, niaid, national institute of allergy and infectious diseases, eukaryotic protein kinase-like fold, alpha/beta protein, transferase, phosphotransferase, aminoglycoside phosphotransferase, antibiotic resistance, aminoglycosides, kanamycin, gtp, intracellular |
| Biological source | Acinetobacter baumannii |
| Total number of polymer chains | 3 |
| Total formula weight | 103424.08 |
| Authors | Stogios, P.J.,Minasov, G.,Tan, K.,Evdokimova, E.,Egorova, O.,Di Leo, R.,Shakya, T.,Wright, G.D.,Savchenko, A.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2012-04-06, release date: 2012-04-18, Last modification date: 2013-09-04) |
| Primary citation | Stogios, P.J.,Spanogiannopoulos, P.,Evdokimova, E.,Egorova, O.,Shakya, T.,Todorovic, N.,Capretta, A.,Wright, G.D.,Savchenko, A. Structure-guided optimization of protein kinase inhibitors reverses aminoglycoside antibiotic resistance. Biochem.J., 454:191-200, 2013 Cited by PubMed: 23758273DOI: 10.1042/BJ20130317 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.29 Å) |
Structure validation
Download full validation report
