4EJ7

Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, ATP-bound

Replaces:  3R78

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Aminoglycoside 3'-phosphotransferase AphA1-IAB	polymer	292	33771.8	3	UniProt (B0VD92)	Acinetobacter baumannii
2	D, J, P (A, B, C)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	3	Chemie (ATP)
3	E, F, G, H, K... (A, B, C)	CALCIUM ION	non-polymer		40.1	12	Chemie (CA)
4	I (A)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
5	T, U, V (A, B, C)	water	water		18.0	294	Chemie (HOH)

Sequence modifications

A, B, C: 1 - 271 (UniProt: B0VD92)

PDB	External Database	Details
Mse -20	-	expression tag
Gly -19	-	expression tag
Ser -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Arg -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	101315.5
Non-Polymers*	Number of molecules	16
	Total formula weight	2108.6
All*	Total formula weight	103424.1

*Water molecules are not included.