PDB: 224004 件ウェブページステータス検索Chemie searchBIRD

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1B3Y	XYLANASE FROM PENICILLIUM SIMPLICISSIMUM, COMPLEX WITH XYLOTETRAOSE 分子名称: PROTEIN (XYLANASE), alpha-D-xylopyranose, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose 著者 Schmidt, A, Kratky, C. 登録日 1998-12-15 公開日 1999-04-06 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Xylan binding subsite mapping in the xylanase from Penicillium simplicissimum using xylooligosaccharides as cryo-protectant. Biochemistry, 38, 1999
4UMJ	Native structure of Farnesyl Pyrophosphate Synthase from Pseudomonas aeruginosa PA01, with bound ibandronic acid molecules. 分子名称: GERANYLTRANSTRANSFERASE, IBANDRONATE, MAGNESIUM ION 著者 Schmidberger, J.W, Schnell, R, Schneider, G. 登録日 2014-05-18 公開日 2015-03-11 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural Characterization of Substrate and Inhibitor Binding to Farnesyl Pyrophosphate Synthase from Pseudomonas Aeruginosa. Acta Crystallogr.,Sect.D, 71, 2015
7NMI	Transactivation domain of p53 in complex with S100P, using annexin A2 as crystallization chaperone 分子名称: CALCIUM ION, Cellular tumor antigen p53, GLYCEROL, ... 著者 Ecsedi, P, Nyitray, L. 登録日 2021-02-23 公開日 2022-03-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Transactivation domain of p53 in complex with S100P using annexin A2 as a crystallization chaperone To Be Published
7NEM	Hydrogenase-2 variant R479K - anaerobically oxidised form 分子名称: CARBONMONOXIDE-(DICYANO) IRON, CHLORIDE ION, FE3-S4 CLUSTER, ... 著者 Carr, S.B. 登録日 2021-02-04 公開日 2022-03-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 A comprehensive structural and kinetic investigation of the role of the active-site argininein bidirectional hydrogen activation by the [NiFe]-hydrogenase "Hyd-2) from Escherichia coli To Be Published
4UIU	BROMODOMAIN OF HUMAN BRD9 WITH 7-(3,4-dimethoxyphenyl)-N-(1,1-dioxo-1- thian-4-yl)-5-methyl-4-oxo-4H,5H-thieno-3,2-c-pyridine-2-carboxamide 分子名称: BROMODOMAIN-CONTAINING PROTEIN 9, N-[1,1-bis(oxidanylidene)thian-4-yl]-7-(3,4-dimethoxyphenyl)-5-methyl-4-oxidanylidene-thieno[3,2-c]pyridine-2-carboxamide 著者 Chung, C, Theodoulou, N.T, Bamborough, P, Humphreys, P.G. 登録日 2015-04-03 公開日 2015-04-22 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 The Discovery of I-Brd9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition. J.Med.Chem., 59, 2016
4ULW	Crystal structure of the ROQ-domain of human ROQUIN1 分子名称: ROQUIN-1 著者 Schuetz, A, Heinemann, U. 登録日 2014-05-14 公開日 2015-01-14 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Roquin Binding to Target Mrnas Involves a Winged Helix-Turn- Helix Motif. Nat.Commun., 5, 2014
4UFY	Crystal structure of human tankyrase 2 in complex with TA-13 分子名称: 8-METHYL-2-(4-METHYLPHENYL)-3,4-DIHYDROQUINAZOLIN-4-ONE, GLYCEROL, SULFATE ION, ... 著者 Haikarainen, T, Lehtio, L. 登録日 2015-03-20 公開日 2016-04-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure-Activity Relationships of 2-Arylquinazolin-4-Ones as Highly Selective and Potent Inhibitors of the Tankyrases. Eur.J.Med.Chem., 118, 2016
4UDX	CO2 bound to cluster C of Ni,Fe-CO dehydrogenase at true-atomic resolution 分子名称: CARBON DIOXIDE, CARBON MONOXIDE DEHYDROGENASE 2, FE (II) ION, ... 著者 Fesseler, J, Jeoung, J.-H, Dobbek, H. 登録日 2014-12-12 公開日 2015-05-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.03 Å) 主引用文献 How the [NiFe4S4] Cluster of CO Dehydrogenase Activates CO2 and NCO(-). Angew. Chem. Int. Ed. Engl., 54, 2015
4UBL	KINETIC CRYSTALLOGRAPHY OF ALPHA_E7-CARBOXYLESTERSE FROM LUCILLA CUPRINA - ABSORBED X-RAY DOSE 9.26 MGy 分子名称: DIETHYL HYDROGEN PHOSPHATE, E3 著者 Jackson, C.J, Carr, P.D, Weik, M, Huber, T, Meirelles, T, Correy, G. 登録日 2014-08-13 公開日 2015-08-19 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Mapping the Accessible Conformational Landscape of an Insect Carboxylesterase Using Conformational Ensemble Analysis and Kinetic Crystallography Structure, 24, 2016
3HII	Crystal structure of human diamine oxidase in complex with the inhibitor pentamidine 分子名称: 1,5-BIS(4-AMIDINOPHENOXY)PENTANE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Amiloride-sensitive amine oxidase, ... 著者 McGrath, A.P, Guss, J.M. 登録日 2009-05-20 公開日 2009-10-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.149 Å) 主引用文献 Structure and inhibition of human diamine oxidase Biochemistry, 48, 2009
1AVB	ARCELIN-1 FROM PHASEOLUS VULGARIS L 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ARCELIN-1, ... 著者 Mourey, L, Pedelacq, J.D, Fabre, C, Rouge, P, Samama, J.P. 登録日 1997-09-15 公開日 1998-10-14 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of the arcelin-1 dimer from Phaseolus vulgaris at 1.9-A resolution. J.Biol.Chem., 273, 1998
7N0E	Co-complex of the histidine kinase region of RetS and the dimerization and histidine phosphotransfer domain of GacS 分子名称: Histidine kinase 著者 Ryan Kaler, K, Schubot, F.D, Nix, J. 登録日 2021-05-25 公開日 2022-03-09 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 RetS inhibits Pseudomonas aeruginosa biofilm formation by disrupting the canonical histidine kinase dimerization interface of GacS. J.Biol.Chem., 297, 2021
1AXM	HEPARIN-LINKED BIOLOGICALLY-ACTIVE DIMER OF FIBROBLAST GROWTH FACTOR 分子名称: 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, ACIDIC FIBROBLAST GROWTH FACTOR 著者 DiGabriele, A.D, Lax, I, Chen, D.I, Svahn, C.M, Jaye, M, Schlessinger, J, Hendrickson, W.A. 登録日 1997-10-16 公開日 1998-04-22 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure of a heparin-linked biologically active dimer of fibroblast growth factor. Nature, 393, 1998
7NPA	Crystal structure of the Coenzyme F420-dependent sulfite reductase from Methanothermococcus thermolithotrophicus at 1.55-A resolution 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... 著者 Jespersen, M, Wagner, T. 登録日 2021-02-26 公開日 2022-03-23 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structures of the sulfite detoxifying F 420 -dependent enzyme from Methanococcales. Nat.Chem.Biol., 2023
4UI8	Crystal structure of human tankyrase 2 in complex with TA-55 分子名称: 8-HYDROXY-2-[4-(TRIFLUOROMETHYL)PHENYL]-3,4-DIHYDROQUINAZOLIN-4-ONE, GLYCEROL, SULFATE ION, ... 著者 Haikarainen, T, Lehtio, L. 登録日 2015-03-27 公開日 2016-04-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structure-Activity Relationships of 2-Arylquinazolin-4-Ones as Highly Selective and Potent Inhibitors of the Tankyrases. Eur.J.Med.Chem., 118, 2016
4UHI	HUMAN STEROL 14-ALPHA DEMETHYLASE (CYP51) IN COMPLEX WITH VFV IN C121 SPACE GROUP 分子名称: N-[(1R)-1-(3,4'-difluorobiphenyl-4-yl)-2-(1H-imidazol-1-yl)ethyl]-4-(5-phenyl-1,3,4-oxadiazol-2-yl)benzamide, PROTOPORPHYRIN IX CONTAINING FE, STEROL 14-ALPHA DEMETHYLASE 著者 Hargrove, T.Y, Wawrzak, Z, I Lepesheva, G. 登録日 2015-03-24 公開日 2016-06-08 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Human Sterol 14Alpha-Demethylase (Cyp51) as a Target for Anticancer Chemotherapy: Towards Structure-Aided Drug Design. J.Lipid Res., 57, 2016
7NNJ	Crystal Structure of NUDT4 (Diphosphoinositol polyphosphate phosphohydrolase 2) in complex with 4-O-Bn-1-PCP-InsP4 (AMR2105) 分子名称: 1,2-ETHANEDIOL, Diphosphoinositol polyphosphate phosphohydrolase 2, FORMIC ACID, ... 著者 Dubianok, Y, Arruda Bezerra, G, Raux, B, Diaz Saez, L, Riley, A.M, Potter, B.V.L, Huber, K.V.M, von Delft, F. 登録日 2021-02-24 公開日 2022-03-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.755 Å) 主引用文献 Crystal Structure of NUDT4 (Diphosphoinositol polyphosphate phosphohydrolase 2) in complex with 4-O-Bn-1-PCP-InsP4 (AMR2105) To Be Published
4UCT	Fragment bound to H.influenza NAD dependent DNA ligase 分子名称: 1-(2,4-dimethylbenzyl)-6-oxo-1,6-dihydropyridine-3-carboxamide, 2-amino-6-methyl-5-(propan-2-yloxy)-3H-[1,2,4]triazolo[1,5-a]pyrimidin-8-ium, DNA LIGASE 著者 Hale, M, Brassington, C, Carcanague, D, Embrey, K, Eyermann, C.J, Giacobbe, R.A, Gingipali, L, Gowravaram, M, Harang, J, Howard, T, Ioannidis, G, Jahic, H, Kutschke, A, Laganas, V.A, Loch, J, Miller, M.D, Murphy-Benenato, K.E, Oguto, H, Otterbein, L, Patel, S.J, Shapiro, A.B, Boriack-Sjodin, P.A. 登録日 2014-12-04 公開日 2015-10-14 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 From Fragments to Leads: Novel Bacterial Nad+-Dependent DNA Ligase Inhibitors Tetrahedron Lett., 56, 2015
4UI7	Crystal structure of human tankyrase 2 in complex with TA-49 分子名称: 8-HYDROXY-2-(4-METHYLPHENYL)-3,4-DIHYDROQUINAZOLIN-4-ONE, GLYCEROL, SULFATE ION, ... 著者 Haikarainen, T, Lehtio, L. 登録日 2015-03-27 公開日 2016-04-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure-Activity Relationships of 2-Arylquinazolin-4-Ones as Highly Selective and Potent Inhibitors of the Tankyrases. Eur.J.Med.Chem., 118, 2016
7NP8	Crystal structure of the Coenzyme F420-dependent sulfite reductase from Methanocaldococcus jannaschii at 2.3-A resolution 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, CHLORIDE ION, ... 著者 Jespersen, M, Wagner, T. 登録日 2021-02-26 公開日 2022-03-23 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structures of the sulfite detoxifying F 420 -dependent enzyme from Methanococcales. Nat.Chem.Biol., 2023
7MYV	Plasmodium falciparum HAD5/PMM 分子名称: MAGNESIUM ION, Phosphomannomutase 著者 Frasse, P.M, Odom John, A.R, Goldberg, D.E. 登録日 2021-05-21 公開日 2022-03-30 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.51 Å) 主引用文献 Enzymatic and structural characterization of HAD5, an essential phosphomannomutase of malaria-causing parasites. J.Biol.Chem., 298, 2022
7ZY9	Structure of D165A/D167A double mutant of Chit33 from Trichoderma harzianum complexed with chitintetraose. 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Endochitinase 33 著者 Jimenez-Ortega, E, Sanz-Aparicio, J. 登録日 2022-05-24 公開日 2022-08-31 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure-Function Insights into the Fungal Endo -Chitinase Chit33 Depict its Mechanism on Chitinous Material. Int J Mol Sci, 23, 2022
4UB9	Structural and catalytic characterization of molinate hydrolase 分子名称: Molinate hydrolase, ZINC ION 著者 Leite, J.P, Duarte, M, Paiva, A, Ferreira-da-Silva, F, Matias, P.M, Nunes, O, Gales, L. 登録日 2014-08-12 公開日 2015-06-24 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Structure-guided engineering of molinate hydrolase for the degradation of thiocarbamate pesticides. Plos One, 10, 2015
7N3S	Human bisphosphoglycerate mutase complex with 2-phosphoglycolate 分子名称: 2-PHOSPHOGLYCOLIC ACID, Bisphosphoglycerate mutase 著者 Aljahdali, A.S, Musayev, F.N, Safo, M.K. 登録日 2021-06-01 公開日 2022-04-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Molecular insight into 2-phosphoglycolate activation of the phosphatase activity of bisphosphoglycerate mutase. Acta Crystallogr D Struct Biol, 78, 2022
7N3R	The ternary complex of human Bisphosphoglycerate mutase with 3-phosphoglycerate and 2-phosphoglycolate 分子名称: 2-PHOSPHOGLYCOLIC ACID, 3-PHOSPHOGLYCERIC ACID, Bisphosphoglycerate mutase 著者 Aljahdali, A.S, Musayev, F.N, Safo, M.K. 登録日 2021-06-01 公開日 2022-04-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Molecular insight into 2-phosphoglycolate activation of the phosphatase activity of bisphosphoglycerate mutase. Acta Crystallogr D Struct Biol, 78, 2022

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