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1HS2
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BU of 1hs2 by Molmil
SOLUTION STRUCTURE OF RNA HAIRPIN LOOP UUAAGU AS PART OF HAIRPIN R(GCGUUAAGUCGCA)
分子名称: 5'-R(*GP*CP*GP*UP*UP*AP*AP*GP*UP*CP*GP*CP*A)-3'
著者Zhang, H, Fountain, M.A, Krugh, T.R.
登録日2000-12-22
公開日2001-08-29
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural characterization of a six-nucleotide RNA hairpin loop found in Escherichia coli, r(UUAAGU).
Biochemistry, 40, 2001
1HS4
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BU of 1hs4 by Molmil
SOLUTION STRUCTURE OF RNA HAIRPIN LOOP UUAAAU AS PART OF HAIRPIN R(GCGUUAAAUCGCA)
分子名称: 5'-R(*GP*CP*GP*UP*UP*AP*AP*AP*UP*CP*GP*CP*A)-3'
著者Zhang, H, Culyba, M, Volkman, H, Krugh, T.R.
登録日2000-12-22
公開日2003-09-02
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural Characterization of Six-Nucleotide RNA Hairpin loops: r(UUAAUU), r(UUAAAU), r(UUAACU)
To be Published
3L82
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BU of 3l82 by Molmil
X-ray Crystal structure of TRF1 and Fbx4 complex
分子名称: F-box only protein 4, Telomeric repeat-binding factor 1
著者Zeng, Z.X, Wang, W, Yang, Y.T, Chen, Y, Yang, X.M, Diehl, J.A, Liu, X.D, Lei, M.
登録日2009-12-29
公開日2010-03-09
最終更新日2013-09-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis of Selective Ubiquitination of TRF1 by SCF(Fbx4)
Dev.Cell, 18, 2010
3SQD
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BU of 3sqd by Molmil
Crystal structure of human PTIP BRCT5/6-gamma H2AX complex
分子名称: Histone H2A.x, PAX-interacting protein 1
著者Yan, W, Shao, Z.H.
登録日2011-07-05
公開日2011-11-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.153 Å)
主引用文献Crystal structure of human PTIP BRCT5/6-gamma H2AX
To be Published
3UMZ
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BU of 3umz by Molmil
Crystal Structure of the human MDC1 FHA Domain
分子名称: Mediator of DNA damage checkpoint protein 1
著者Luo, S, Ye, K.
登録日2011-11-15
公開日2012-01-25
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain
Nucleic Acids Res., 40, 2012
3SHV
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BU of 3shv by Molmil
Crystal structure of human MCPH1 tandem BRCT domains-gamma H2AX complex
分子名称: Histone H2A.x, Microcephalin
著者Shao, Z.H, Li, F.D, Yan, W.
登録日2011-06-17
公開日2011-12-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Specific recognition of phosphorylated tail of H2AX by the tandem BRCT domains of MCPH1 revealed by complex structure
J.Struct.Biol., 177, 2012
3UNM
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BU of 3unm by Molmil
Crystal Structure of The Human MDC1 FHA Domain
分子名称: Mediator of DNA damage checkpoint protein 1
著者Luo, S, Ye, K.
登録日2011-11-16
公開日2012-01-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain
Nucleic Acids Res., 40, 2012
3VA4
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BU of 3va4 by Molmil
Crystal structure of the mammalian MDC1 FHA domain complexed with CHK2 pThr68 peptide
分子名称: Mediator of DNA damage checkpoint protein 1, Serine/threonine-protein kinase Chk2
著者Wu, H.H, Wu, P.Y, Huang, K.F, Kao, Y.Y, Tsai, M.D.
登録日2011-12-28
公開日2012-02-01
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Structural Delineation of MDC1-FHA Domain Binding with CHK2-pThr68.
Biochemistry, 2012
4GAC
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BU of 4gac by Molmil
High resolution structure of mouse aldehyde reductase (AKR1a4) in its apo-form
分子名称: 1,2-ETHANEDIOL, Alcohol dehydrogenase [NADP(+)], CITRATE ANION
著者Faucher, F, Jia, Z.
登録日2012-07-25
公開日2012-11-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献High-resolution structure of AKR1a4 in the apo form and its interaction with ligands.
Acta Crystallogr.,Sect.F, 68, 2012
1YCR
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BU of 1ycr by Molmil
MDM2 BOUND TO THE TRANSACTIVATION DOMAIN OF P53
分子名称: MDM2, P53
著者Kussie, P.H, Pavletich, N.P.
登録日1996-09-30
公開日1997-11-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain.
Science, 274, 1996
1YCQ
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BU of 1ycq by Molmil
XENOPUS LAEVIS MDM2 BOUND TO THE TRANSACTIVATION DOMAIN OF HUMAN P53
分子名称: MDM2, P53
著者Kussie, P.H, Pavletich, N.P.
登録日1996-09-30
公開日1997-11-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain.
Science, 274, 1996
1YCB
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BU of 1ycb by Molmil
DISTAL POCKET POLARITY IN LIGAND BINDING TO MYOGLOBIN: DEOXY AND CARBONMONOXY FORMS OF A THREONINE68 (E11) MUTANT INVESTIGATED BY X-RAY CRYSTALLOGRAPHY AND INFRARED SPECTROSCOPY
分子名称: MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
著者Cameron, A.D, Smerdon, S.J, Wilkinson, A.J, Habash, J, Helliwell, J.R.
登録日1993-08-10
公開日1994-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Distal pocket polarity in ligand binding to myoglobin: deoxy and carbonmonoxy forms of a threonine68(E11) mutant investigated by X-ray crystallography and infrared spectroscopy.
Biochemistry, 32, 1993
1YCA
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BU of 1yca by Molmil
DISTAL POCKET POLARITY IN LIGAND BINDING TO MYOGLOBIN: DEOXY AND CARBONMONOXY FORMS OF A THREONINE68 (E11) MUTANT INVESTIGATED BY X-RAY CRYSTALLOGRAPHY AND INFRARED SPECTROSCOPY
分子名称: CARBON MONOXIDE, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
著者Cameron, A.D, Smerdon, S.J, Wilkinson, A.J, Habash, J, Helliwell, J.R.
登録日1993-08-10
公開日1994-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Distal pocket polarity in ligand binding to myoglobin: deoxy and carbonmonoxy forms of a threonine68(E11) mutant investigated by X-ray crystallography and infrared spectroscopy.
Biochemistry, 32, 1993
2AZM
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BU of 2azm by Molmil
Crystal structure of the MDC1 brct repeat in complex with the histone tail of gamma-H2AX
分子名称: GAMMA-H2AX HISTONE, Mediator of DNA damage checkpoint protein 1
著者Clapperton, J.A, Stucki, M, Mohammad, D, Yaffe, M.B, Jackson, S.P, Smerdon, S.J.
登録日2005-09-12
公開日2006-01-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献MDC1 Directly Binds Phosphorylated Histone H2AX to Regulate Cellular Responses to DNA Double-Strand Breaks
Cell(Cambridge,Mass.), 123, 2005
6J67
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BU of 6j67 by Molmil
Crystal structure of the compound 34 in a complex with TRF2
分子名称: 3FB-PHE-B8R-LEU-5XU-PRO, Telomeric repeat-binding factor 2
著者Chen, Y, Yang, Y, Lei, M.
登録日2019-01-14
公開日2019-02-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Cyclic Peptidic Mimetics of Apollo Peptides Targeting Telomeric Repeat Binding Factor 2 (TRF2) and Apollo Interaction.
ACS Med Chem Lett, 9, 2018
6HMO
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BU of 6hmo by Molmil
Solution structure of the RNA duplex formed by the 5'-end of U1snRNA and the 5'-splice site of SMN2 exon7 in complex with the SMN-C5 splicing modifier
分子名称: 2-(8-fluoranyl-2-methyl-imidazo[1,2-a]pyridin-6-yl)-7-(4-methylpiperazin-1-yl)pyrido[1,2-a]pyrimidin-4-one, RNA (5'-R(*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3'), RNA (5'-R(*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3')
著者Campagne, S, Allain, F.H.
登録日2018-09-12
公開日2019-08-14
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis of a small molecule targeting RNA for a specific splicing correction.
Nat.Chem.Biol., 15, 2019
6KJ4
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BU of 6kj4 by Molmil
120kV MicroED structure of FUS (37-42) SYSGYS solved from single crystal at 0.65 A
分子名称: RNA-binding protein FUS
著者Zhou, H, Luo, F, Luo, Z, Li, D, Liu, C, Li, X.
登録日2019-07-20
公開日2019-10-02
最終更新日2024-03-27
実験手法ELECTRON CRYSTALLOGRAPHY (0.65 Å)
主引用文献Programming Conventional Electron Microscopes for Solving Ultrahigh-Resolution Structures of Small and Macro-Molecules.
Anal.Chem., 91, 2019
6KJ2
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BU of 6kj2 by Molmil
200kV MicroED structure of FUS (37-42) SYSGYS solved from single crystal at 0.67 A
分子名称: RNA-binding protein FUS
著者Zhou, H, Luo, F, Luo, Z, Li, D, Liu, C, Li, X.
登録日2019-07-20
公開日2019-10-02
最終更新日2024-03-27
実験手法ELECTRON CRYSTALLOGRAPHY (0.67 Å)
主引用文献Programming Conventional Electron Microscopes for Solving Ultrahigh-Resolution Structures of Small and Macro-Molecules.
Anal.Chem., 91, 2019
6KJ3
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BU of 6kj3 by Molmil
120kV MicroED structure of FUS (37-42) SYSGYS solved from merged datasets at 0.60 A
分子名称: RNA-binding protein FUS
著者Zhou, H, Luo, F, Luo, Z, Li, D, Liu, C, Li, X.
登録日2019-07-20
公開日2019-10-02
最終更新日2024-03-27
実験手法ELECTRON CRYSTALLOGRAPHY (0.6 Å)
主引用文献Programming Conventional Electron Microscopes for Solving Ultrahigh-Resolution Structures of Small and Macro-Molecules.
Anal.Chem., 91, 2019
6KE6
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BU of 6ke6 by Molmil
3.4 angstrom cryo-EM structure of yeast 90S small subunit preribosome
分子名称: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ...
著者Du, Y, Ye, K, An, W.
登録日2019-07-03
公開日2020-08-05
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献3.4 angstrom cryo-EM structure of yeast 90S small subunit preribosome
To be published
6KJ1
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BU of 6kj1 by Molmil
200kV MicroED structure of FUS (37-42) SYSGYS solved from merged datasets at 0.65 A
分子名称: RNA-binding protein FUS
著者Zhou, H, Luo, F, Luo, Z, Li, D, Liu, C, Li, X.
登録日2019-07-20
公開日2019-10-02
最終更新日2024-03-27
実験手法ELECTRON CRYSTALLOGRAPHY (0.65 Å)
主引用文献Programming Conventional Electron Microscopes for Solving Ultrahigh-Resolution Structures of Small and Macro-Molecules.
Anal.Chem., 91, 2019
6K0J
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BU of 6k0j by Molmil
The co-crystal structure of DYRK2 with a small molecule inhibitor
分子名称: 3-(2,7-dimethoxyacridin-9-yl)sulfanylpropan-1-amine, Dual specificity tyrosine-phosphorylation-regulated kinase 2
著者Tiantian, W, Xiao, J.
登録日2019-05-06
公開日2019-11-20
最終更新日2019-12-18
実験手法X-RAY DIFFRACTION (2.352 Å)
主引用文献Inhibition of dual-specificity tyrosine phosphorylation-regulated kinase 2 perturbs 26S proteasome-addicted neoplastic progression.
Proc.Natl.Acad.Sci.USA, 116, 2019
6HMI
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BU of 6hmi by Molmil
Solution structure of the RNA duplex formed by the 5'-end of U1snRNA and the 5'-splice site of SMN2 exon7
分子名称: RNA (5'-R(*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3'), RNA (5'-R(*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3')
著者Campagne, S, Allain, F.H.
登録日2018-09-12
公開日2019-08-14
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Structural basis of a small molecule targeting RNA for a specific splicing correction.
Nat.Chem.Biol., 15, 2019
1AU5
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BU of 1au5 by Molmil
SOLUTION STRUCTURE OF INTRASTRAND CISPLATIN-CROSSLINKED DNA OCTAMER D(CCTG*G*TCC):D(GGACCAGG), NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: Cisplatin, DNA (5'-D(*CP*CP*TP*GP*GP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*CP*CP*AP*GP*G)-3')
著者Yang, D, Van Boom, S.S.G.E, Reedijk, J, Van Boom, J.H, Wang, A.H.-J.
登録日1997-09-11
公開日1998-02-25
最終更新日2024-04-10
実験手法SOLUTION NMR
主引用文献Structure and isomerization of an intrastrand cisplatin-cross-linked octamer DNA duplex by NMR analysis.
Biochemistry, 34, 1995
1ATV
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BU of 1atv by Molmil
HAIRPIN WITH AGAA TETRALOOP, NMR, 4 STRUCTURES
分子名称: RNA (5'-R(*GP*GP*GP*AP*CP*CP*AP*GP*AP*AP*GP*GP*UP*CP*CP*CP*G)-3')
著者Kang, H.
登録日1997-08-14
公開日1998-02-25
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Primary Sequence at the Junction of Stem and Loop in RNA Hairpins Affects the Three-Dimensional Conformation in Solution
To be Published

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件を2024-07-17に公開中

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