PDB: 658 件ウェブページステータス検索Chemie searchBIRD

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6R81	Multidrug resistance transporter BmrA mutant E504A bound with ATP and Mg solved by Cryo-EM 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Lipid A export ATP-binding/permease protein MsbA, MAGNESIUM ION 著者 Wiseman, B, Chaptal, V, Zampieri, V, Magnard, S, Hogbom, M, Falson, P. 登録日 2019-03-30 公開日 2020-05-06 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Substrate-bound and substrate-free outward-facing structures of a multidrug ABC exporter. Sci Adv, 8, 2022
2I6W	Crystal structure of the multidrug efflux transporter AcrB 分子名称: Acriflavine resistance protein B 著者 Das, D, Xu, Q.S, Kim, S.H. 登録日 2006-08-29 公開日 2007-05-01 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Crystal structure of the multidrug efflux transporter AcrB at 3.1A resolution reveals the N-terminal region with conserved amino acids. J.Struct.Biol., 158, 2007
8UWU	EmrE structure in the proton-bound state (WT/L51I heterodimer) 分子名称: SMR family multidrug efflux protein EmrE 著者 Li, J, Sae Her, A, Besch, A, Ramirez, B, Crames, M, Banigan, J.R, Mueller, C, Marsiglia, W.M, Zhang, Y, Traaseth, N.J. 登録日 2023-11-08 公開日 2024-05-29 最終更新日 2024-07-03 実験手法 SOLID-STATE NMR, SOLUTION NMR 主引用文献 Dynamics underlie the drug recognition mechanism by the efflux transporter EmrE. Nat Commun, 15, 2024
6A6M	Crystal structure of an outward-open nucleotide-bound state of the eukaryotic ABC multidrug transporter CmABCB1 分子名称: ATP-binding cassette, sub-family B, member 1, ... 著者 Kato, H, Nakatsu, T, Kodan, A. 登録日 2018-06-28 公開日 2019-02-20 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Inward- and outward-facing X-ray crystal structures of homodimeric P-glycoprotein CmABCB1. Nat Commun, 10, 2019
6A6N	Crystal structure of an inward-open apo state of the eukaryotic ABC multidrug transporter CmABCB1 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ATP-binding cassette, sub-family B, ... 著者 Kato, H, Nakatsu, T, Kodan, A. 登録日 2018-06-28 公開日 2019-01-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.02 Å) 主引用文献 Inward- and outward-facing X-ray crystal structures of homodimeric P-glycoprotein CmABCB1. Nat Commun, 10, 2019
3AOD	Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket 分子名称: (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, Acriflavine resistance protein B, RIFAMPICIN 著者 Nakashima, R, Sakurai, K, Yamaguchi, A. 登録日 2010-09-23 公開日 2011-11-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket Nature, 480, 2011
3AOB	Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket 分子名称: Acriflavine resistance protein B, RIFAMPICIN 著者 Nakashima, R, Sakurai, K, Yamaguchi, A. 登録日 2010-09-23 公開日 2011-11-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket Nature, 480, 2011
3AOC	Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket 分子名称: Acriflavine resistance protein B, ERYTHROMYCIN A 著者 Nakashima, R, Sakurai, K, Yamaguchi, A. 登録日 2010-09-23 公開日 2011-11-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.34 Å) 主引用文献 Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket Nature, 480, 2011
3AOA	Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket 分子名称: Acriflavine resistance protein B 著者 Nakashima, R, Sakurai, K, Yamaguchi, A. 登録日 2010-09-23 公開日 2011-11-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket Nature, 480, 2011
2HQD	Conformation of the AcrB Multidrug Efflux Pump in Mutants of the Putative Proton Relay Pathway 分子名称: Acriflavine resistance protein B 著者 Su, C.-C, Li, M, Gu, R, Takatsuka, Y, McDermott, G, Nikaido, H, Yu, E.W. 登録日 2006-07-18 公開日 2007-04-17 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.65 Å) 主引用文献 Conformation of the AcrB multidrug efflux pump in mutants of the putative proton relay pathway J.Bacteriol., 188, 2006
2HQF	Conformation of the AcrB Multidrug Efflux Pump in Mutants of the Putative Proton Relay Pathway 分子名称: Acriflavine resistance protein B 著者 Su, C.-C, Li, M, Gu, R, Takatsuka, Y, McDermott, G, Nikaido, H, Yu, E.W. 登録日 2006-07-18 公開日 2007-04-17 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3.38 Å) 主引用文献 Conformation of the AcrB multidrug efflux pump in mutants of the putative proton relay pathway J.Bacteriol., 188, 2006
2HQC	Conformation of the AcrB Multidrug Efflux Pump in Mutants of the Putative Proton Relay Pathway 分子名称: Acriflavine resistance protein B 著者 Su, C.-C, Li, M, Gu, R, Takatsuka, Y, McDermott, G, Nikaido, H, Yu, E.W. 登録日 2006-07-18 公開日 2007-04-17 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3.56 Å) 主引用文献 Conformation of the AcrB multidrug efflux pump in mutants of the putative proton relay pathway J.Bacteriol., 188, 2006
2HQG	Conformation of the AcrB Multidrug Efflux Pump in Mutants of the Putative Proton Relay Pathway 分子名称: Acriflavine resistance protein B 著者 Su, C.-C, Li, M, Gu, R, Takatsuka, Y, McDermott, G, Nikaido, H, Yu, E.W. 登録日 2006-07-18 公開日 2007-04-17 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3.38 Å) 主引用文献 Conformation of the AcrB multidrug efflux pump in mutants of the putative proton relay pathway J.Bacteriol., 188, 2006
2ONK	ABC transporter ModBC in complex with its binding protein ModA 分子名称: MAGNESIUM ION, Molybdate/tungstate ABC transporter, ATP-binding protein, ... 著者 Hollenstein, K, Frei, D.C, Locher, K.P. 登録日 2007-01-24 公開日 2007-03-06 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structure of an ABC transporter in complex with its binding protein. Nature, 446, 2007
6OWS	Cryo-EM structure of an Acinetobacter baumannii multidrug efflux pump 分子名称: Efflux pump membrane transporter, PHOSPHATIDYLETHANOLAMINE 著者 Su, C.-C. 登録日 2019-05-10 公開日 2019-06-19 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (2.98 Å) 主引用文献 Cryo-Electron Microscopy Structure of an Acinetobacter baumannii Multidrug Efflux Pump. Mbio, 10, 2019
7B8Q	Acinetobacter baumannii multidrug transporter AdeB in L*OO state 分子名称: Efflux pump membrane transporter 著者 Ornik-Cha, A, Reitz, J, Seybert, A, Frangakis, A, Pos, K.M. 登録日 2020-12-13 公開日 2021-10-20 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.84 Å) 主引用文献 Structural and functional analysis of the promiscuous AcrB and AdeB efflux pumps suggests different drug binding mechanisms. Nat Commun, 12, 2021
7B8P	Acinetobacter baumannii multidrug transporter AdeB in OOO state 分子名称: Efflux pump membrane transporter 著者 Ornik-Cha, A, Reitz, J, Seybert, A, Frangakis, A, Pos, K.M. 登録日 2020-12-13 公開日 2021-10-20 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.54 Å) 主引用文献 Structural and functional analysis of the promiscuous AcrB and AdeB efflux pumps suggests different drug binding mechanisms. Nat Commun, 12, 2021
2CBZ	Structure of the human Multidrug Resistance Protein 1 Nucleotide Binding Domain 1 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1 著者 Ramaen, O, Leulliot, N, Sizun, C, Ulryck, N, Pamlard, O, Lallemand, J.-Y, van Tilbeurgh, H, Jacquet, E. 登録日 2006-01-10 公開日 2006-05-17 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure of the Human Multidrug Resistance Protein 1 Nucleotide Binding Domain 1 Bound to Mg(2+)/ATP Reveals a Non-Productive Catalytic Site. J.Mol.Biol., 359, 2006
8FFK	Klebsiella pneumoniae AcrB multidrug efflux pump apo form 分子名称: Efflux pump membrane transporter 著者 Zhang, Z. 登録日 2022-12-08 公開日 2023-04-05 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.82 Å) 主引用文献 Cryo-EM Structures of the Klebsiella pneumoniae AcrB Multidrug Efflux Pump. Mbio, 14, 2023
8FFS	Erythromycin bound Klebsiella pneumoniae AcrB multidrug efflux pump 分子名称: ERYTHROMYCIN A, Efflux pump membrane transporter 著者 Zhang, Z. 登録日 2022-12-09 公開日 2023-04-05 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.96 Å) 主引用文献 Cryo-EM Structures of the Klebsiella pneumoniae AcrB Multidrug Efflux Pump. Mbio, 14, 2023
3WMG	Crystal structure of an inward-facing eukaryotic ABC multidrug transporter G277V/A278V/A279V mutant in complex with an cyclic peptide inhibitor, aCAP 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ATP-binding cassette, sub-family B, ... 著者 Kodan, A, Yamaguchi, T, Nakatsu, T, Sakiyama, K, Hipolito, C.J, Fujioka, A, Hirokane, R, Ikeguchi, K, Watanabe, B, Hirtake, J, Kimura, Y, Suga, H, Ueda, K, Kato, H. 登録日 2013-11-18 公開日 2014-04-30 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis for gating mechanisms of a eukaryotic P-glycoprotein homolog. Proc.Natl.Acad.Sci.USA, 111, 2014
3WME	Crystal structure of an inward-facing eukaryotic ABC multidrug transporter 分子名称: ATP-binding cassette, sub-family B, member 1, ... 著者 Kodan, A, Yamaguchi, T, Nakatsu, T, Kato, H. 登録日 2013-11-18 公開日 2014-03-19 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.751 Å) 主引用文献 Structural basis for gating mechanisms of a eukaryotic P-glycoprotein homolog. Proc.Natl.Acad.Sci.USA, 111, 2014
6TQE	The structure of ABC transporter Rv1819c without addition of substrate 分子名称: ABC transporter ATP-binding protein/permease, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION 著者 Rempel, S, Gati, C, Slotboom, D.J, Guskov, A. 登録日 2019-12-16 公開日 2020-04-01 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 A mycobacterial ABC transporter mediates the uptake of hydrophilic compounds. Nature, 580, 2020
6TQF	The structure of ABC transporter Rv1819c in AMP-PNP bound state 分子名称: ABC transporter ATP-binding protein/permease, DODECYL-BETA-D-MALTOSIDE, MAGNESIUM ION, ... 著者 Rempel, S, Gati, C, Slotboom, D.J, Guskov, A. 登録日 2019-12-16 公開日 2020-04-01 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 A mycobacterial ABC transporter mediates the uptake of hydrophilic compounds. Nature, 580, 2020
1L7V	Bacterial ABC Transporter Involved in B12 Uptake 分子名称: CYCLO-TETRAMETAVANADATE, VITAMIN B12 TRANSPORT SYSTEM PERMEASE PROTEIN BTUC, Vitamin B12 transport ATP-binding protein btuD 著者 Locher, K.P, Lee, A.T, Rees, D.C. 登録日 2002-03-18 公開日 2002-05-15 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 The E. coli BtuCD structure: a framework for ABC transporter architecture and mechanism. Science, 296, 2002

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