PDB: 1396 件ウェブページステータス検索Chemie searchBIRD

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6T29	Crystal structure of human calmodulin-dependent protein kinase 1D (CAMK1D) bound to compound 18 (CS587) 分子名称: 1,2-ETHANEDIOL, 2-[(3~{S})-3-azanylpiperidin-1-yl]-4-[[3,5-bis(2-cyanopropan-2-yl)phenyl]amino]pyrimidine-5-carboxamide, Calcium/calmodulin-dependent protein kinase type 1D, ... 著者 Kraemer, A, Sorrell, F, Butterworth, S, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2019-10-08 公開日 2019-11-13 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.484 Å) 主引用文献 Discovery of Highly Selective Inhibitors of Calmodulin-Dependent Kinases That Restore Insulin Sensitivity in the Diet-Induced Obesityin VivoMouse Model. J.Med.Chem., 63, 2020
6MUD	Voltage-gated sodium channel NaV1.5 C-terminal domain in complex with Ca2+/Calmodulin 分子名称: CALCIUM ION, Calmodulin-1, Sodium channel protein type 5 subunit alpha 著者 Gardill, B.R, Tung, C.C, Van Petegem, F. 登録日 2018-10-23 公開日 2019-05-08 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Crystal structures of Ca2+-calmodulin bound to NaVC-terminal regions suggest role for EF-hand domain in binding and inactivation. Proc.Natl.Acad.Sci.USA, 116, 2019
6MUE	Voltage-gated sodium channel NaV1.4 IQ domain in complex with Ca2+/Calmodulin 分子名称: CALCIUM ION, Calmodulin-1, Sodium channel protein type 4 subunit alpha 著者 Gardill, B.R, Van Petegem, F. 登録日 2018-10-23 公開日 2019-05-08 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structures of Ca2+-calmodulin bound to NaVC-terminal regions suggest role for EF-hand domain in binding and inactivation. Proc.Natl.Acad.Sci.USA, 116, 2019
2RO8	Solution structure of calcium bound soybean calmodulin isoform 1 N-terminal domain 分子名称: CALCIUM ION, Calmodulin 著者 Ishida, H, Huang, H, Yamniuk, A.P, Takaya, Y, Vogel, H.J. 登録日 2008-03-14 公開日 2008-04-08 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 The solution structures of two soybean calmodulin isoforms provide a structural basis for their selective target activation properties J.Biol.Chem., 283, 2008
6PJX	Crystal Structure of G Protein-Coupled Receptor Kinase 5 (GRK5) in Complex with Calmodulin (CaM) 分子名称: CALCIUM ION, Calmodulin, G protein-coupled receptor kinase 5, ... 著者 Bhardwaj, A, Komolov, K.E, Sulon, S, Benovic, J.L. 登録日 2019-06-28 公開日 2020-12-09 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Structure of a GRK5-Calmodulin Complex Reveals Molecular Mechanism of GRK Activation and Substrate Targeting. Mol.Cell, 81, 2021
7L8V	NMR Structure of half-calcified calmodulin mutant (CaMEF12) bound to the IQ-motif of CaV1.2 分子名称: CALCIUM ION, Calmodulin-1, Voltage-dependent L-type calcium channel subunit alpha-1C 著者 Ames, J.B. 登録日 2021-01-01 公開日 2022-07-06 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Half-calcified calmodulin promotes basal activity and inactivation of the L-type calcium channel Ca V 1.2. J.Biol.Chem., 298, 2022
1DEG	THE LINKER OF DES-GLU84 CALMODULIN IS BENT AS SEEN IN THE CRYSTAL STRUCTURE 分子名称: CALCIUM ION, CALMODULIN 著者 Raghunathan, S, Chandross, R, Cheng, B.P, Persechini, A, Sobottk, S.E, Kretsinger, R.H. 登録日 1993-06-07 公開日 1994-05-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The linker of des-Glu84-calmodulin is bent. Proc.Natl.Acad.Sci.Usa, 90, 1993
1MUX	SOLUTION NMR STRUCTURE OF CALMODULIN/W-7 COMPLEX: THE BASIS OF DIVERSITY IN MOLECULAR RECOGNITION, 30 STRUCTURES 分子名称: CALCIUM ION, CALMODULIN, N-(6-AMINOHEXYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE 著者 Osawa, M, Swindells, M.B, Tanikawa, J, Tanaka, T, Mase, T, Furuya, T, Ikura, M. 登録日 1997-09-06 公開日 1998-10-14 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure of calmodulin-W-7 complex: the basis of diversity in molecular recognition. J.Mol.Biol., 276, 1998
3CLN	STRUCTURE OF CALMODULIN REFINED AT 2.2 ANGSTROMS RESOLUTION 分子名称: CALCIUM ION, CALMODULIN 著者 Babu, Y.S, Bugg, C.E, Cook, W.J. 登録日 1988-05-11 公開日 1988-07-16 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of calmodulin refined at 2.2 A resolution. J.Mol.Biol., 204, 1988
1NIW	Crystal structure of endothelial nitric oxide synthase peptide bound to calmodulin 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Nitric-oxide synthase, ... 著者 Aoyagi, M, Arvai, A.S, Tainer, J.A, Getzoff, E.D. 登録日 2002-12-26 公開日 2003-02-18 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural basis for endothelial nitric oxide synthase binding to calmodulin Embo J., 22, 2003
2BBM	SOLUTION STRUCTURE OF A CALMODULIN-TARGET PEPTIDE COMPLEX BY MULTIDIMENSIONAL NMR 分子名称: CALCIUM ION, CALMODULIN, MYOSIN LIGHT CHAIN KINASE 著者 Clore, G.M, Bax, A, Ikura, M, Gronenborn, A.M. 登録日 1992-07-16 公開日 1994-01-31 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure of a calmodulin-target peptide complex by multidimensional NMR. Science, 256, 1992
2BBN	SOLUTION STRUCTURE OF A CALMODULIN-TARGET PEPTIDE COMPLEX BY MULTIDIMENSIONAL NMR 分子名称: CALCIUM ION, CALMODULIN, MYOSIN LIGHT CHAIN KINASE 著者 Clore, G.M, Bax, A, Ikura, M, Gronenborn, A.M. 登録日 1992-07-16 公開日 1994-01-31 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure of a calmodulin-target peptide complex by multidimensional NMR. Science, 256, 1992
1CDL	TARGET ENZYME RECOGNITION BY CALMODULIN: 2.4 ANGSTROMS STRUCTURE OF A CALMODULIN-PEPTIDE COMPLEX 分子名称: CALCIUM ION, CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II ALPHA CHAIN, CALMODULIN 著者 Meador, W.E, Quiocho, F.A. 登録日 1993-10-08 公開日 1994-08-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Target enzyme recognition by calmodulin: 2.4 A structure of a calmodulin-peptide complex. Science, 257, 1992
1CTR	DRUG BINDING BY CALMODULIN: CRYSTAL STRUCTURE OF A CALMODULIN-TRIFLUOPERAZINE COMPLEX 分子名称: 10-[3-(4-METHYL-PIPERAZIN-1-YL)-PROPYL]-2-TRIFLUOROMETHYL-10H-PHENOTHIAZINE, CALCIUM ION, CALMODULIN 著者 Cook, W.J, Walter, L.J, Walter, M.R. 登録日 1994-09-21 公開日 1994-12-20 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Drug binding by calmodulin: crystal structure of a calmodulin-trifluoperazine complex. Biochemistry, 33, 1994
3IF7	Structure of Calmodulin complexed with its first endogenous inhibitor, sphingosylphosphorylcholine 分子名称: 2-{[(R)-{[(2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl]oxy}(hydroxy)phosphoryl]oxy}-N,N,N-trimethylethanaminium, CALCIUM ION, Calmodulin 著者 Kovacs, E, Harmat, V, Toth, J, Vertessy, B.G, Modos, K, Kardos, J, Liliom, K. 登録日 2009-07-24 公開日 2010-06-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure and mechanism of calmodulin binding to a signaling sphingolipid reveal new aspects of lipid-protein interactions Faseb J., 24, 2010
5TP6	Solution structure of the CaM34 with the iNOS CaM binding domain peptide 分子名称: Calmodulin, Nitric oxide synthase, inducible 著者 Piazza, M, Dieckmann, T, Guillemette, J.G. 登録日 2016-10-19 公開日 2017-09-27 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Structural Consequences of Calmodulin EF Hand Mutations. Biochemistry, 56, 2017
3G43	Crystal structure of the calmodulin-bound Cav1.2 C-terminal regulatory domain dimer 分子名称: CALCIUM ION, Calmodulin, Voltage-dependent L-type calcium channel subunit alpha-1C 著者 Fallon, J.L, Quiocho, F.A. 登録日 2009-02-03 公開日 2009-03-03 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of dimeric cardiac L-type calcium channel regulatory domains bridged by Ca2+{middle dot}calmodulins. Proc.Natl.Acad.Sci.USA, 106, 2009
2LV6	The complex between Ca-Calmodulin and skeletal muscle myosin light chain kinase from combination of NMR and aqueous and contrast-matched SAXS data 分子名称: CALCIUM ION, Calmodulin, Myosin light chain kinase 2, ... 著者 Grishaev, A.V, Anthis, N.J, Clore, G.M. 登録日 2012-06-29 公開日 2013-02-20 最終更新日 2024-05-01 実験手法 SOLUTION NMR, SOLUTION SCATTERING 主引用文献 Contrast-matched small-angle X-ray scattering from a heavy-atom-labeled protein in structure determination: application to a lead-substituted calmodulin-peptide complex. J.Am.Chem.Soc., 134, 2012
2L7L	Solution structure of Ca2+/calmodulin complexed with a peptide representing the calmodulin-binding domain of calmodulin kinase I 分子名称: CALCIUM ION, Calcium/calmodulin-dependent protein kinase type 1, Calmodulin 著者 Gifford, J.L, Ishida, H, Vogel, H.J. 登録日 2010-12-13 公開日 2011-05-18 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Fast methionine-based solution structure determination of calcium-calmodulin complexes. J.Biomol.Nmr, 50, 2011
3EWV	Crystal Structure of calmodulin complexed with a peptide 分子名称: CALCIUM ION, Calmodulin, Tumor necrosis factor receptor superfamily member 16 著者 Jiang, T, Cao, P, Gong, Y, Yu, H.J, Gui, W.J, Zhang, W.T. 登録日 2008-10-16 公開日 2009-10-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural insights into the mechanism of calmodulin binding to death receptors. Acta Crystallogr.,Sect.D, 70, 2014
2N27	Competitive inhibition of TRPV1 calmodulin interaction by vanilloids 分子名称: (6E)-N-(4-hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide, CALCIUM ION, Calmodulin 著者 Hetenyi, A, Nemeth, L, Weber, E, Szakonyi, G, Winter, Z, Josvay, K, Bartus, E, Olah, Z, Martinek, T.A. 登録日 2015-04-29 公開日 2016-07-06 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Competitive inhibition of TRPV1-calmodulin interaction by vanilloids. Febs Lett., 590, 2016
2KN2	Solution structure of the C-terminal domain of soybean calmodulin isoform 4 fused with the calmodulin-binding domain of NtMKP1 分子名称: CALCIUM ION, Calmodulin 著者 Ishida, H, Rainaldi, M, Vogel, H.J. 登録日 2009-08-12 公開日 2009-08-25 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structural studies of soybean calmodulin isoform 4 bound to the calmodulin-binding domain of tobacco mitogen-activated protein kinase phosphatase-1 provide insights into a sequential target binding mode. J.Biol.Chem., 284, 2009
2LQC	NMR solution structure of a Ca2+-Calmodulin with a binding motif (NSCaTE) peptide from the N-terminal cytoplasmic domain of the L-type Voltage-Cated Calcium Channel alpha1C subunit 分子名称: CALCIUM ION, Calmodulin, Voltage-dependent L-type calcium channel subunit alpha-1C 著者 Liu, Z. 登録日 2012-02-29 公開日 2012-06-06 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Structural basis for the regulation of L-type voltage-gated calcium channels: interactions between the N-terminal cytoplasmic domain and Ca(2+)-calmodulin. Front Mol Neurosci, 5, 2012
2KDU	Structural basis of the Munc13-1/Ca2+-Calmodulin interaction: A novel 1-26 calmodulin binding motif with a bipartite binding mode 分子名称: CALCIUM ION, Calmodulin, Protein unc-13 homolog A 著者 Rodriguez-Castaneda, F.A, Maestre-Martinez, M, Coudevylle, N, Dimova, K, Jahn, O, Junge, H, Becker, S, Brose, N, Carlomagno, T, Griesinger, C. 登録日 2009-01-19 公開日 2009-12-15 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Modular architecture of Munc13/calmodulin complexes: dual regulation by Ca2+ and possible function in short-term synaptic plasticity. Embo J., 29, 2010
2LGF	Solution structure of Ca2+/calmodulin complexed with a peptide representing the calmodulin-binding domain of L-selectin 分子名称: CALCIUM ION, Calmodulin, L-selectin 著者 Gifford, J.L, Ishida, H, Vogel, H.J. 登録日 2011-07-25 公開日 2012-06-13 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural Insights into Calmodulin-regulated L-selectin Ectodomain Shedding. J.Biol.Chem., 287, 2012

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