7DYS
 
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6BQR
 | | Human TRPM4 ion channel in lipid nanodiscs in a calcium-free state | | 分子名称: | CHOLESTEROL HEMISUCCINATE, Transient receptor potential cation channel subfamily M member 4 | | 著者 | Autzen, H.E, Myasnikov, A.G, Campbell, M.G, Asarnow, D, Julius, D, Cheng, Y. | | 登録日 | 2017-11-28 | | 公開日 | 2017-12-20 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure of the human TRPM4 ion channel in a lipid nanodisc.
Science, 359, 2018
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6BQV
 | | Human TRPM4 ion channel in lipid nanodiscs in a calcium-bound state | | 分子名称: | CALCIUM ION, CHOLESTEROL HEMISUCCINATE, Transient receptor potential cation channel subfamily M member 4 | | 著者 | Autzen, H.E, Myasnikov, A.G, Campbell, M.G, Asarnow, D, Julius, D, Cheng, Y. | | 登録日 | 2017-11-28 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structure of the human TRPM4 ion channel in a lipid nanodisc.
Science, 359, 2018
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6DMW
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6E7P
 | | cryo-EM structure of human TRPML1 with PI35P2 | | 分子名称: | (1R,2S,3S,4R,5S,6R)-5-{[(R)-[(2R)-2,3-bis{[(1S)-1-hydroxyoctyl]oxy}propoxy](hydroxy)phosphoryl]oxy}-2,4,6-trihydroxycyclohexane-1,3-diyl bis[dihydrogen (phosphate)], Mucolipin-1 | | 著者 | Schmiege, P, Li, X. | | 登録日 | 2018-07-27 | | 公開日 | 2018-11-28 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural basis for PtdInsP2-mediated human TRPML1 regulation.
Nat Commun, 9, 2018
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6E7Y
 | | cryo-EM structure of human TRPML1 with PI45P2 | | 分子名称: | Mucolipin-1, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | | 著者 | Schmiege, P, Li, X. | | 登録日 | 2018-07-27 | | 公開日 | 2018-11-28 | | 実験手法 | ELECTRON MICROSCOPY (3.57 Å) | | 主引用文献 | Structural basis for PtdInsP2-mediated human TRPML1 regulation.
Nat Commun, 9, 2018
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6E7Z
 | | cryo-EM structure of human TRPML1 with ML-SA1 and PI35P2 | | 分子名称: | (1R,2S,3S,4R,5S,6R)-5-{[(R)-[(2R)-2,3-bis{[(1S)-1-hydroxyoctyl]oxy}propoxy](hydroxy)phosphoryl]oxy}-2,4,6-trihydroxycyclohexane-1,3-diyl bis[dihydrogen (phosphate)], 2-{2-oxo-2-[(4S)-2,2,4-trimethyl-3,4-dihydroquinolin-1(2H)-yl]ethyl}-1H-isoindole-1,3(2H)-dione, Mucolipin-1 | | 著者 | Schmiege, P, Li, X. | | 登録日 | 2018-07-27 | | 公開日 | 2018-11-28 | | 実験手法 | ELECTRON MICROSCOPY (3.73 Å) | | 主引用文献 | Structural basis for PtdInsP2-mediated human TRPML1 regulation.
Nat Commun, 9, 2018
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6DMR
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6DMU
 | | PI(4,5)P2 bound full-length rbTRPV5 | | 分子名称: | Transient receptor potential cation channel subfamily V member 5, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | | 著者 | Hughes, T.E.T, Pumroy, R.A, Moiseenkova-Bell, V.Y. | | 登録日 | 2018-06-05 | | 公開日 | 2018-10-24 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structural insights on TRPV5 gating by endogenous modulators.
Nat Commun, 9, 2018
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7WRA
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7WRD
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7WRF
 | | Mouse TRPM8 in lipid nanodiscs in the presence of calcium, icilin and PI(4,5)P2 | | 分子名称: | CALCIUM ION, Icilin, SODIUM ION, ... | | 著者 | Zhao, C, Xie, Y, Guo, J. | | 登録日 | 2022-01-26 | | 公開日 | 2022-06-22 | | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | | 主引用文献 | Structures of a mammalian TRPM8 in closed state.
Nat Commun, 13, 2022
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7WRB
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7WRC
 | | Mouse TRPM8 in LMNG in the presence of calcium, icilin and PI(4,5)P2 | | 分子名称: | CALCIUM ION, Icilin, Transient receptor potential cation channel subfamily M member 8 | | 著者 | Zhao, C, Xie, Y, Guo, J. | | 登録日 | 2022-01-26 | | 公開日 | 2022-06-22 | | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | | 主引用文献 | Structures of a mammalian TRPM8 in closed state.
Nat Commun, 13, 2022
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7WRE
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6HRS
 | | Structure of the TRPML2 ELD at pH 4.5 | | 分子名称: | GLYCEROL, Mucolipin-2 | | 著者 | Bader, N, Viet, K.K, Wagner, A, Hellmich, U.A, Schindelin, H. | | 登録日 | 2018-09-28 | | 公開日 | 2019-06-19 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structure of the Human TRPML2 Ion Channel Extracytosolic/Lumenal Domain.
Structure, 27, 2019
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6HRR
 | | Structure of the TRPML2 ELD at pH 6.5 | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, GLYCEROL, ... | | 著者 | Bader, N, Viet, K.K, Wagner, A, Hellmich, U.A. | | 登録日 | 2018-09-28 | | 公開日 | 2019-06-19 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of the Human TRPML2 Ion Channel Extracytosolic/Lumenal Domain.
Structure, 27, 2019
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6PVQ
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6PVN
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6PVL
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6PVM
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5IWR
 | | Structure of Transient Receptor Potential (TRP) channel TRPV6 in the presence of barium | | 分子名称: | 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, BARIUM ION, Transient receptor potential cation channel subfamily V member 6 | | 著者 | Saotome, K, Singh, A.K, Yelshanskaya, M.V, Sobolevsky, A.I. | | 登録日 | 2016-03-22 | | 公開日 | 2016-06-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.85 Å) | | 主引用文献 | Crystal structure of the epithelial calcium channel TRPV6.
Nature, 534, 2016
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5IWT
 | | Structure of Transient Receptor Potential (TRP) channel TRPV6 in the presence of gadolinium | | 分子名称: | 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, GADOLINIUM ATOM, Transient receptor potential cation channel subfamily V member 6 | | 著者 | Saotome, K, Singh, A.K, Yelshanskaya, M.V, Sobolevsky, A.I. | | 登録日 | 2016-03-22 | | 公開日 | 2016-06-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Crystal structure of the epithelial calcium channel TRPV6.
Nature, 534, 2016
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5IWK
 | | Structure of Transient Receptor Potential (TRP) channel TRPV6 | | 分子名称: | 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, CALCIUM ION, Transient receptor potential cation channel subfamily V member 6 | | 著者 | Saotome, K, Singh, A.K, Yelshanskaya, M.V, Sobolevsky, A.I. | | 登録日 | 2016-03-22 | | 公開日 | 2016-06-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.247 Å) | | 主引用文献 | Crystal structure of the epithelial calcium channel TRPV6.
Nature, 534, 2016
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5IWP
 | | Structure of Transient Receptor Potential (TRP) channel TRPV6 in the presence of calcium | | 分子名称: | 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, CALCIUM ION, Transient receptor potential cation channel subfamily V member 6 | | 著者 | Saotome, K, Singh, A.K, Yelshanskaya, M.V, Sobolevsky, A.I. | | 登録日 | 2016-03-22 | | 公開日 | 2016-06-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.65 Å) | | 主引用文献 | Crystal structure of the epithelial calcium channel TRPV6.
Nature, 534, 2016
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