PDB: 287 件ウェブページステータス検索Chemie searchBIRD

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4XO3	Crystal Structure of E. coli Aminopeptidase N in complex with L-Leucine 分子名称: Aminopeptidase N, GLYCEROL, LEUCINE, ... 著者 Addlagatta, A, Gumpena, R. 登録日 2015-01-16 公開日 2016-01-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of E. coli Aminopeptidase N in complex with L-Leucine To Be Published
4XMX	Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with Bestatin 分子名称: 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, Aminopeptidase N, GLYCEROL, ... 著者 Addlagatta, A, Gumpena, R, Kishor, C. 登録日 2015-01-15 公開日 2016-02-10 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with Bestatin To Be Published
4XN5	Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-Phenylalanine 分子名称: Aminopeptidase N, GLYCEROL, MALONATE ION, ... 著者 Addlagatta, A, Gumpena, R, Kishor, C. 登録日 2015-01-15 公開日 2016-02-10 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-Phenylalanine To Be Published
4XMW	Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-aspartic acid 分子名称: ASPARTIC ACID, Aminopeptidase N, GLYCEROL, ... 著者 Addlagatta, A, Gumpena, R, Kishor, C. 登録日 2015-01-15 公開日 2016-02-10 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-aspartic acid To Be Published
4XMV	Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-Arginine 分子名称: ARGININE, Aminopeptidase N, GLYCEROL, ... 著者 Addlagatta, A, Gumpena, R, Kishor, C. 登録日 2015-01-15 公開日 2016-02-10 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.92 Å) 主引用文献 Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-arginine To Be Published
4XN1	Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-Glutamate 分子名称: Aminopeptidase N, GLUTAMIC ACID, MALONATE ION, ... 著者 Addlagatta, A, Gumpena, R. 登録日 2015-01-15 公開日 2016-03-02 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-Glutamate To Be Published
4XNB	Crystal Structure of E. coli Aminopeptidase N in complex with L-Beta Homophenylalanine 分子名称: (3S)-3-AMINO-4-PHENYLBUTANOIC ACID, Aminopeptidase N, GLYCEROL, ... 著者 Addlagatta, A, Gumpena, R. 登録日 2015-01-15 公開日 2016-03-02 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal Structure of E. coli Aminopeptidase N in complex with L-Beta Homophenylalanine To Be Published
4XO5	Crystal Structure of E. coli Aminopeptidase N in complex with L-Glutamate 分子名称: Aminopeptidase N, GLUTAMIC ACID, GLYCEROL, ... 著者 Addlagatta, A, Gumpena, R. 登録日 2015-01-16 公開日 2016-01-20 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Crystal Structure of E. coli Aminopeptidase N in complex with L-Glutamate To Be Published
4Z7I	Crystal structure of insulin regulated aminopeptidase in complex with ligand 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DG025 transition-state analogue enzyme inhibitor, ... 著者 Mpakali, A, Saridakis, E, Harlos, K, Zhao, Y, Stratikos, E. 登録日 2015-04-07 公開日 2015-08-26 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.31 Å) 主引用文献 Crystal Structure of Insulin-Regulated Aminopeptidase with Bound Substrate Analogue Provides Insight on Antigenic Epitope Precursor Recognition and Processing. J Immunol., 195, 2015
4ZW5	X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 9f 分子名称: M1 family aminopeptidase, MAGNESIUM ION, ZINC ION, ... 著者 Drinkwater, N, McGowan, S. 登録日 2015-05-19 公開日 2016-03-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions. Eur.J.Med.Chem., 110, 2016
4ZX5	X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 10q 分子名称: DIMETHYL SULFOXIDE, GLYCEROL, M1 family aminopeptidase, ... 著者 Drinkwater, N, McGowan, S. 登録日 2015-05-20 公開日 2016-03-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions. Eur.J.Med.Chem., 110, 2016
4ZW6	X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 9q 分子名称: DIMETHYL SULFOXIDE, GLYCEROL, M1 family aminopeptidase, ... 著者 Drinkwater, N, McGowan, S. 登録日 2015-05-19 公開日 2016-03-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions. Eur.J.Med.Chem., 110, 2016
4ZW3	X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 9b 分子名称: GLYCEROL, M1 family aminopeptidase, MAGNESIUM ION, ... 著者 Drinkwater, N, McGowan, S. 登録日 2015-05-19 公開日 2016-03-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions. Eur.J.Med.Chem., 110, 2016
4ZX4	X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 10o 分子名称: DIMETHYL SULFOXIDE, GLYCEROL, M1 family aminopeptidase, ... 著者 Drinkwater, N, McGowan, S. 登録日 2015-05-20 公開日 2016-03-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions. Eur.J.Med.Chem., 110, 2016
5AB2	Crystal structure of aminopeptidase ERAP2 with ligand 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Mpakali, A, Giastas, P, Saridakis, E, Mavridis, I.M, Stratikos, E. 登録日 2015-07-31 公開日 2015-09-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.729 Å) 主引用文献 Structural Basis for Antigenic Peptide Recognition and Processing by Endoplasmic Reticulum (Er) Aminopeptidase 2. J.Biol.Chem., 290, 2015
5AEN	Structure of human Leukotriene A4 hydrolase in complex with inhibitor dimethyl(2- (4-phenoxyphenoxy)ethyl)amine 分子名称: IMIDAZOLE, LEUKOTRIENE A-4 HYDROLASE, N,N-dimethyl-2-(4-phenoxyphenoxy)ethanamine, ... 著者 Moser, D, Wittmann, S.K, Kramer, J, Blocher, R, Achenbach, J, Pogoryelov, D, Proschak, E. 登録日 2015-01-06 公開日 2015-02-11 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.864 Å) 主引用文献 Peng: A Neural Gas-Based Approach for Pharmacophore Elucidation. Method Design, Validation and Virtual Screening for Novel Ligands of Lta4H. J.Chem.Inf.Model., 55, 2015
4ZQT	Crystal structure of PfA-M1 with virtual ligand inhibitor 分子名称: (2R)-2-{[(R)-[(R)-amino(phenyl)methyl](hydroxy)phosphoryl]methyl}-4-methylpentanoic acid, GLYCEROL, M1 family aminopeptidase, ... 著者 Ruggeri, C, Drinkwater, N, McGowan, S. 登録日 2015-05-11 公開日 2015-10-07 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.981 Å) 主引用文献 Identification and Validation of a Potent Dual Inhibitor of the P. falciparum M1 and M17 Aminopeptidases Using Virtual Screening. Plos One, 10, 2015
5BPP	Structure of human Leukotriene A4 hydrolase in complex with inhibitor 4AZ 分子名称: 2-(4-butoxyphenyl)-N-hydroxyacetamide, ACETATE ION, Leukotriene A-4 hydrolase, ... 著者 Huang, J, Dong, N.N, Xiao, Q, Ou, P.Y, Wu, D, Lu, W.Q. 登録日 2015-05-28 公開日 2016-08-10 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Bufexamac ameliorates LPS-induced acute lung injury in mice by targeting LTA4H Sci Rep, 6, 2016
4ZW7	X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 9m 分子名称: DIMETHYL SULFOXIDE, GLYCEROL, M1 family aminopeptidase, ... 著者 Drinkwater, N, McGowan, S. 登録日 2015-05-19 公開日 2016-03-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions. Eur.J.Med.Chem., 110, 2016
5AB0	Crystal structure of aminopeptidase ERAP2 with ligand 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Mpakali, A, Giastas, P, Saridakis, E, Stratikos, E. 登録日 2015-07-31 公開日 2015-09-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Basis for Antigenic Peptide Recognition and Processing by Endoplasmic Reticulum (Er) Aminopeptidase 2. J.Biol.Chem., 290, 2015
4ZW8	X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 9r 分子名称: DIMETHYL SULFOXIDE, GLYCEROL, M1 family aminopeptidase, ... 著者 Drinkwater, N, McGowan, S. 登録日 2015-05-19 公開日 2016-03-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions. Eur.J.Med.Chem., 110, 2016
4ZX6	X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 10s 分子名称: DIMETHYL SULFOXIDE, GLYCEROL, M1 family aminopeptidase, ... 著者 Drinkwater, N, McGowan, S. 登録日 2015-05-20 公開日 2016-03-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions. Eur.J.Med.Chem., 110, 2016
4ZX3	X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 10b 分子名称: DIMETHYL SULFOXIDE, M1 family aminopeptidase, MAGNESIUM ION, ... 著者 Drinkwater, N, McGowan, S. 登録日 2015-05-20 公開日 2016-03-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions. Eur.J.Med.Chem., 110, 2016
4HOM	Crystal structure of porcine aminopeptidase-N complexed with substance P 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Chen, L, Lin, Y.L, Peng, G, Li, F. 登録日 2012-10-22 公開日 2012-10-31 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural basis for multifunctional roles of mammalian aminopeptidase N. Proc.Natl.Acad.Sci.USA, 109, 2012
4JBS	Crystal structure of the human Endoplasmic Reticulum Aminopeptidase 2 in complex with PHOSPHINIC PSEUDOTRIPEPTIDE inhibitor. 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Endoplasmic reticulum aminopeptidase 2, ... 著者 Saridakis, E, Birtley, J, Stratikos, E, Mavridis, I.M. 登録日 2013-02-20 公開日 2013-12-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.789 Å) 主引用文献 Rationally designed inhibitor targeting antigen-trimming aminopeptidases enhances antigen presentation and cytotoxic T-cell responses. Proc.Natl.Acad.Sci.USA, 110, 2013

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