5AEN
Structure of human Leukotriene A4 hydrolase in complex with inhibitor dimethyl(2- (4-phenoxyphenoxy)ethyl)amine
Summary for 5AEN
Entry DOI | 10.2210/pdb5aen/pdb |
Descriptor | LEUKOTRIENE A-4 HYDROLASE, N,N-dimethyl-2-(4-phenoxyphenoxy)ethanamine, ZINC ION, ... (6 entities in total) |
Functional Keywords | hydrolase, leukotriene (lt) a4 hydrolase/aminopeptidase, lta4h |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 1 |
Total formula weight | 70159.61 |
Authors | Moser, D.,Wittmann, S.K.,Kramer, J.,Blocher, R.,Achenbach, J.,Pogoryelov, D.,Proschak, E. (deposition date: 2015-01-06, release date: 2015-02-11, Last modification date: 2024-01-10) |
Primary citation | Moser, D.,Wittmann, S.K.,Kramer, J.,Blocher, R.,Achenbach, J.,Pogoryelov, D.,Proschak, E. Peng: A Neural Gas-Based Approach for Pharmacophore Elucidation. Method Design, Validation and Virtual Screening for Novel Ligands of Lta4H. J.Chem.Inf.Model., 55:284-, 2015 Cited by PubMed: 25625859DOI: 10.1021/CI500618U PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.864 Å) |
Structure validation
Download full validation report