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5AEN

Structure of human Leukotriene A4 hydrolase in complex with inhibitor dimethyl(2- (4-phenoxyphenoxy)ethyl)amine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
LEUKOTRIENE A-4 HYDROLASEpolymer60869006.51UniProt (P09960)
Pfam (PF17900)
Pfam (PF01433)
Pfam (PF09127)
HOMO SAPIENS (HUMAN)LTA-4 HYDROLASE, LEUKOTRIENE A4 HYDROLASE, LEUKOTRIENE A(4)
2B
(A)
N,N-dimethyl-2-(4-phenoxyphenoxy)ethanaminenon-polymer257.31Chemie (DP8)
3C
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
4D, E, F, G
(A)
YTTERBIUM (III) IONnon-polymer173.04Chemie (YB)
5H, I
(A)
IMIDAZOLEnon-polymer69.12Chemie (IMD)
6J
(A)
waterwater18.0608Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight69006.5
Non-Polymers*Number of molecules8
Total formula weight1153.1
All*Total formula weight70159.6
*Water molecules are not included.

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PDB entries from 2025-07-16

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