5AB2

Crystal structure of aminopeptidase ERAP2 with ligand

Summary for 5AB2

• Entry DOI: 10.2210/pdb5ab2/pdb
• Related: 5AB0
• Descriptor: ENDOPLASMIC RETICULUM AMINOPEPTIDASE 2, GPI, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• Functional Keywords: aminopeptidase, erap2, zinc ion binding, endoplasmic reticulum, hydrolase, metalloprotease, l-rap, antigen presentation
• Biological source: HOMO SAPIENS (HUMAN); More
• Total number of polymer chains: 4
• Total formula weight: 230868.20

Authors

Mpakali, A.,Giastas, P.,Saridakis, E.,Mavridis, I.M.,Stratikos, E. (deposition date: 2015-07-31, release date: 2015-09-30, Last modification date: 2024-01-10)

• Primary citation: Mpakali, A.,Giastas, P.,Mathioudakis, N.,Mavridis, I.M.,Saridakis, E.,Stratikos, E.; Structural Basis for Antigenic Peptide Recognition and Processing by Endoplasmic Reticulum (Er) Aminopeptidase 2.; J.Biol.Chem., 290:26021-, 2015; PubMed: 26381406; DOI: 10.1074/JBC.M115.685909

Experimental method

X-RAY DIFFRACTION (2.729 Å)