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1MH3
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maltose binding-a1 homeodomain protein chimera, crystal form I
分子名称: maltose binding-a1 homeodomain protein chimera
著者Ke, A, Wolberger, C.
登録日2002-08-19
公開日2002-09-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Insights into binding cooperativity of MATa1/MATalpha2 from the crystal structure of a MATa1 homeodomain-maltose binding protein chimera
Protein Sci., 12, 2003
5EG0
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BU of 5eg0 by Molmil
HOXB13-MEIS1 heterodimer bound to DNA
分子名称: DNA (5'-D(*CP*CP*TP*CP*GP*TP*AP*AP*AP*AP*CP*TP*GP*TP*CP*AP*AP*C)-3'), DNA (5'-D(P*GP*TP*TP*GP*AP*CP*AP*GP*TP*TP*TP*TP*AP*CP*GP*AP*GP*G)-3'), Homeobox protein Hox-B13, ...
著者Morgunova, E, Yin, Y, Jolma, A, Popov, A, Taipale, J.
登録日2015-10-26
公開日2016-11-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.101 Å)
主引用文献Molecular basis of recognition of two distinct DNA sequences by a single transcription factor
To Be Published
1MH4
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BU of 1mh4 by Molmil
maltose binding-a1 homeodomain protein chimera, crystal form II
分子名称: maltose binding-a1 homeodomain protein chimera
著者Ke, A, Wolberger, C.
登録日2002-08-19
公開日2002-09-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Insights into binding cooperativity of MATa1/MATalpha2 from the crystal structure of a MATa1 homeodomain-maltose binding protein chimera
Protein Sci., 12, 2003
8G88
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BU of 8g88 by Molmil
Human Oct4 bound to nucleosome with human nMatn1 sequence
分子名称: Histone H2A, Histone H2B, Histone H3, ...
著者Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M.
登録日2023-02-17
公開日2023-03-22
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
8G87
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BU of 8g87 by Molmil
Human Oct4 bound to nucleosome with human nMatn1 sequence (focused refinement of Oct4 bound region)
分子名称: POU domain, class 5, transcription factor 1, ...
著者Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M.
登録日2023-02-17
公開日2023-03-22
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (8.1 Å)
主引用文献Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
8G8B
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BU of 8g8b by Molmil
Nucleosome with human nMatn1 sequence in complex with Human Oct4
分子名称: Histone H2A, Histone H2B, Histone H3, ...
著者Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M.
登録日2023-02-17
公開日2023-03-22
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
8G8G
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BU of 8g8g by Molmil
Interaction of H3 tail in LIN28B nucleosome with Oct4
分子名称: Histone H2A, Histone H2B, Histone H3, ...
著者Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M.
登録日2023-02-17
公開日2023-03-22
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
8G8E
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BU of 8g8e by Molmil
Human Oct4 bound to nucleosome with human LIN28B sequence
分子名称: LIN28B DNA (32-MER), POU domain, class 5, ...
著者Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M.
登録日2023-02-17
公開日2023-03-22
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
1AU7
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PIT-1 MUTANT/DNA COMPLEX
分子名称: CONSENSUS DNA 25-MER, DNA (5'-D(*CP*TP*TP*CP*CP*TP*CP*AP*TP*GP*TP*AP*TP*AP*TP*AP*C P*AP*TP*GP*AP*GP* GP*A)-3'), PROTEIN PIT-1
著者Jacobson, E.M, Li, P, Leon-Del-Rio, A, Rosenfeld, M.G, Aggarwal, A.K.
登録日1997-09-12
公開日1998-01-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of Pit-1 POU domain bound to DNA as a dimer: unexpected arrangement and flexibility.
Genes Dev., 11, 1997
1B8I
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BU of 1b8i by Molmil
STRUCTURE OF THE HOMEOTIC UBX/EXD/DNA TERNARY COMPLEX
分子名称: DNA (5'-D(*AP*CP*GP*TP*GP*AP*TP*TP*TP*AP*TP*GP*GP*CP*G)-3'), DNA (5'-D(*GP*TP*CP*GP*CP*CP*AP*TP*AP*AP*AP*TP*CP*AP*C)-3'), PROTEIN (HOMEOBOX PROTEIN EXTRADENTICLE), ...
著者Passner, J.M, Ryoo, H.-D, Shen, L, Mann, R.S, Aggarwal, A.K.
登録日1999-02-01
公開日1999-04-12
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of a DNA-bound Ultrabithorax-Extradenticle homeodomain complex.
Nature, 397, 1999
2R5Y
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Structure of Scr/Exd complex bound to a consensus Hox-Exd site
分子名称: DNA (5'-D(*DAP*DCP*DTP*DCP*DTP*DAP*DTP*DGP*DAP*DTP*DTP*DTP*DAP*DTP*DGP*DGP*DGP*DCP*DTP*DG)-3'), DNA (5'-D(*DTP*DCP*DAP*DGP*DCP*DCP*DCP*DAP*DTP*DAP*DAP*DAP*DTP*DCP*DAP*DTP*DAP*DGP*DAP*DG)-3'), Homeobox protein extradenticle, ...
著者Aggarwal, A.K, Passner, J.M, Jain, R.
登録日2007-09-04
公開日2008-02-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Functional specificity of a Hox protein mediated by the recognition of minor groove structure
Cell(Cambridge,Mass.), 131, 2007
2R5Z
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Structure of Scr/Exd complex bound to a DNA sequence derived from the fkh gene
分子名称: DNA (5'-D(*DAP*DCP*DTP*DCP*DTP*DAP*DAP*DGP*DAP*DTP*DTP*DAP*DAP*DTP*DCP*DGP*DGP*DCP*DTP*DG)-3'), DNA (5'-D(*DTP*DCP*DAP*DGP*DCP*DCP*DGP*DAP*DTP*DTP*DAP*DAP*DTP*DCP*DTP*DTP*DAP*DGP*DAP*DG)-3'), Homeobox protein extradenticle, ...
著者Aggarwal, A.K, Passner, J.M, Jain, R.
登録日2007-09-04
公開日2008-02-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Functional specificity of a Hox protein mediated by the recognition of minor groove structure
Cell(Cambridge,Mass.), 131, 2007
1HF0
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BU of 1hf0 by Molmil
Crystal structure of the DNA-binding domain of Oct-1 bound to DNA as a dimer
分子名称: DNA 5'-D(*CP*AP*CP*AP*TP*TP*TP*GP*AP*AP*AP*GP*GP* CP*AP*AP*AP*TP*GP*GP*AP*G)-3', DNA 5'-D(*CP*TP*CP*CP*AP*TP*TP*TP*GP*CP*CP*TP*TP* TP*CP*AP*AP*AP*TP*GP*TP*G)-3', OCTAMER-BINDING TRANSCRIPTION FACTOR 1
著者Remenyi, A, Tomilin, A, Pohl, E, Scholer, H.R, Wilmanns, M.
登録日2000-11-27
公開日2001-11-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Differential Dimer Activities of the Transcription Factor Oct-1 by DNA-Induced Interface Swapping
Mol.Cell, 8, 2001
1GT0
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BU of 1gt0 by Molmil
Crystal structure of a POU/HMG/DNA ternary complex
分子名称: 5'-D(*AP*TP*CP*CP*CP*AP*TP*TP*AP*GP* CP*AP*TP*CP*CP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3', 5'-D(*TP*TP*CP*TP*TP*TP*GP*TP*TP*TP* GP*GP*AP* TP*GP*CP*TP*AP*AP*TP*GP*GP*GP*A)-3', OCTAMER-BINDING TRANSCRIPTION FACTOR 1, ...
著者Remenyi, A, Wilmanns, M.
登録日2002-01-09
公開日2003-01-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of a POU/Hmg/DNA Ternary Complex Suggests Differential Assembly of Oct4 and Sox2 on Two Enhancers
Genes Dev., 17, 2003
5ZJT
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BU of 5zjt by Molmil
Structure of AbdB/Exd complex bound to a 'Black14' DNA sequence
分子名称: DNA (5'-D(*GP*CP*AP*TP*GP*AP*TP*AP*AP*AP*TP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*AP*TP*TP*TP*AP*TP*CP*AP*TP*GP*C)-3'), Homeobox protein abdominal-B, ...
著者Zeiske, T, Baburajendran, N, Kaczynska, A, Mann, R, Honig, B, Shapiro, L, Palmer, A.G.
登録日2018-03-22
公開日2018-08-29
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Intrinsic DNA Shape Accounts for Affinity Differences between Hox-Cofactor Binding Sites.
Cell Rep, 24, 2018
5ZJS
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BU of 5zjs by Molmil
Structure of AbdB/Exd complex bound to a 'Blue14' DNA sequence
分子名称: DNA (5'-D(*GP*CP*AP*TP*GP*AP*TP*TP*AP*AP*TP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*AP*TP*TP*AP*AP*TP*CP*AP*TP*GP*C)-3'), Homeobox protein abdominal-B, ...
著者Baburajendran, N, Zeiske, T, Kaczynska, A, Mann, R, Honig, B, Shapiro, L, Palmer, A.G.
登録日2018-03-22
公開日2018-08-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.896 Å)
主引用文献Intrinsic DNA Shape Accounts for Affinity Differences between Hox-Cofactor Binding Sites.
Cell Rep, 24, 2018
5WC9
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BU of 5wc9 by Molmil
Human Pit-1 and 4xCATT DNA complex
分子名称: DNA (5'-D(*CP*CP*AP*TP*TP*CP*AP*TP*TP*CP*AP*TP*TP*CP*AP*TP*TP*CP*GP*GP*A)-3'), DNA (5'-D(*CP*CP*GP*AP*AP*TP*GP*AP*AP*TP*GP*AP*AP*TP*GP*AP*AP*TP*GP*GP*T)-3'), Pituitary-specific positive transcription factor 1
著者Agarwal, S, Cho, T.Y.
登録日2017-06-29
公開日2017-11-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Biochemical and structural characterization of a novel cooperative binding mode by Pit-1 with CATT repeats in the macrophage migration inhibitory factor promoter.
Nucleic Acids Res., 46, 2018
5ZJR
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BU of 5zjr by Molmil
Structure of AbdB/Exd complex bound to a 'Magenta14' DNA sequence
分子名称: DNA (5'-D(*GP*TP*CP*GP*TP*AP*AP*AP*TP*CP*AP*TP*GP*C)-3'), DNA (5'-D(P*GP*CP*AP*TP*GP*AP*TP*TP*TP*AP*CP*GP*AP*C)-3'), Homeobox protein abdominal-B, ...
著者Zeiske, T, Baburajendran, N, Kaczynska, A, Mann, R, Honig, B, Shapiro, L, Palmer, A.G.
登録日2018-03-22
公開日2018-08-29
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.03 Å)
主引用文献Intrinsic DNA Shape Accounts for Affinity Differences between Hox-Cofactor Binding Sites.
Cell Rep, 24, 2018
1O4X
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BU of 1o4x by Molmil
TERNARY COMPLEX OF THE DNA BINDING DOMAINS OF THE OCT1 AND SOX2 TRANSCRIPTION FACTORS WITH A 19MER OLIGONUCLEOTIDE FROM THE HOXB1 REGULATORY ELEMENT
分子名称: 5'-D(*CP*AP*TP*TP*AP*GP*CP*AP*TP*GP*AP*CP*AP*AP*AP*GP*AP*CP*A)-3', 5'-D(*TP*GP*TP*CP*TP*TP*TP*GP*TP*CP*AP*TP*GP*CP*TP*AP*AP*TP*G)-3', Transcription factor SOX-2, ...
著者Clore, G.M, Williams, D.C.
登録日2003-07-17
公開日2004-01-27
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Molecular basis for synergistic transcriptional activation by Oct1 and Sox2 revealed from the solution structure of the 42-kDa Oct1.Sox2.Hoxb1-DNA ternary transcription factor complex.
J.Biol.Chem., 279, 2004
1OCT
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CRYSTAL STRUCTURE OF THE OCT-1 POU DOMAIN BOUND TO AN OCTAMER SITE: DNA RECOGNITION WITH TETHERED DNA-BINDING MODULES
分子名称: DNA (5'-D(*AP*CP*CP*TP*TP*AP*TP*TP*TP*GP*CP*AP*TP*AP*C)-3'), DNA (5'-D(*TP*GP*TP*AP*TP*GP*CP*AP*AP*AP*TP*AP*AP*GP*G)-3'), PROTEIN (OCT-1 POU DOMAIN)
著者Klemm, J.D, Rould, M.A, Aurora, R, Herr, W, Pabo, C.O.
登録日1994-05-09
公開日1994-08-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules.
Cell(Cambridge,Mass.), 77, 1994
1S7E
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BU of 1s7e by Molmil
Solution structure of HNF-6
分子名称: Hepatocyte nuclear factor 6
著者Liao, X, Sheng, W.
登録日2004-01-29
公開日2004-12-28
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of the hepatocyte nuclear factor 6alpha and its interaction with DNA.
J.Biol.Chem., 279, 2004
2D5V
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BU of 2d5v by Molmil
Crystal structure of HNF-6alpha DNA-binding domain in complex with the TTR promoter
分子名称: 5'-D(*AP*TP*TP*AP*TP*TP*GP*AP*CP*TP*TP*AP*GP*A)-3', 5'-D(*TP*CP*TP*AP*AP*GP*TP*CP*AP*AP*TP*AP*AP*T)-3', ACETATE ION, ...
著者Iyaguchi, D, Yao, M, Watanabe, N, Nishihira, J, Tanaka, I.
登録日2005-11-07
公開日2006-12-05
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献DNA recognition mechanism of the ONECUT homeodomain of transcription factor HNF-6
Structure, 15, 2007
8OTS
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BU of 8ots by Molmil
OCT4 and MYC-MAX co-bound to a nucleosome
分子名称: DNA (127-MER), Green fluorescent protein,POU domain, class 5, ...
著者Michael, A.K, Stoos, L, Kempf, G, Cavadini, S, Thoma, N.
登録日2023-04-21
公開日2023-05-24
最終更新日2023-07-26
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cooperation between bHLH transcription factors and histones for DNA access.
Nature, 619, 2023
8OSB
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TWIST1-TCF4-ALX4 complex on specific DNA
分子名称: DNA (25-MER), Homeobox protein aristaless-like 4, Transcription factor 4, ...
著者Morgunova, E, Kim, S, Popov, A, Wysocka, J, Taipale, J.
登録日2023-04-18
公開日2024-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献DNA-guided transcription factor cooperativity shapes face and limb mesenchyme.
Cell, 187, 2024

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件を2024-10-16に公開中

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