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5XAJ
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Structural mimicry of the dengue virus envelope glycoprotein revealed by the crystallographic study of an idiotype-anti-idiotype Fab complex.
分子名称: Fab E1 heavy chain, Fab E1 light chain, FabHM14c10 heavy chain, ...
著者Wong, Y.H, Goh, B.C, Lescar, J.
登録日2017-03-13
公開日2017-06-14
最終更新日2017-07-19
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural mimicry of the dengue virus envelope glycoprotein revealed by the crystallographic study of an idiotype-anti-idiotype Fab complex
J. Virol., 2017
1L9K
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dengue methyltransferase
分子名称: RNA-DIRECTED RNA POLYMERASE, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION
著者Egloff, M.P, Benarroch, D, Selisko, B, Romette, J.L, Canard, B.
登録日2002-03-25
公開日2003-03-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献An RNA cap (nucleoside-2'-O-) methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization
Embo J., 21, 2002
6DFJ
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Crystal structure of anti-Zika antibody Z021 bound to DENV-1 envelope protein DIII
分子名称: Dengue 1 Envelope DIII domain, anti-Zika antibody Z021, Heavy Chain, ...
著者Keeffe, J.R, Bjorkman, P.J.
登録日2018-05-14
公開日2018-10-24
最終更新日2018-11-14
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates.
Cell Rep, 25, 2018
1TGE
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The structure of immature Dengue virus at 12.5 angstrom
分子名称: envelope glycoprotein
著者Zhang, Y, Zhang, W, Ogata, S, Clements, D, Strauss, J.H, Baker, T.S, Kuhn, R.J, Rossmann, M.G.
登録日2004-05-28
公開日2004-09-28
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (12.5 Å)
主引用文献Conformational changes of the flavivirus e glycoprotein.
Structure, 12, 2004
5LBV
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Structural basis of zika and dengue virus potent antibody cross-neutralization
分子名称: SODIUM ION, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, envelope protein E
著者Barba-Spaeth, G.
登録日2016-06-17
公開日2016-07-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis of potent Zika-dengue virus antibody cross-neutralization.
Nature, 536, 2016
5LBS
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structural basis of Zika and Dengue virus potent antibody cross-neutralization
分子名称: 1,2-ETHANEDIOL, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE1 C8, SULFATE ION, ...
著者Vaney, M.C, Rouvinski, A, Barba-Spaeth, G, Rey, F.A.
登録日2016-06-17
公開日2016-07-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Structural basis of potent Zika-dengue virus antibody cross-neutralization.
Nature, 536, 2016
1TG8
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The structure of Dengue virus E glycoprotein
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, envelope glycoprotein
著者Zhang, Y, Zhang, W, Ogata, S, Clements, D, Strauss, J.H, Baker, T.S, Rossmann, M.G.
登録日2004-05-28
公開日2004-09-28
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Conformational changes of the flavivirus e glycoprotein
Structure, 12, 2004
5LCV
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Structural basis of Zika and Dengue virus potent antibody cross-neutralization
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 A11, FORMIC ACID, ...
著者Barba-Spaeth, G.
登録日2016-06-22
公開日2016-07-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Structural basis of potent Zika-dengue virus antibody cross-neutralization.
Nature, 536, 2016
4KVC
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2H2 Fab fragment of immature Dengue virus
分子名称: Ig heavy chain V region MOPC 21, Igh protein, Ig kappa chain V-V region MOPC 21, ...
著者Wang, Z, Rossmann, M.G.
登録日2013-05-22
公開日2013-07-24
最終更新日2017-08-02
実験手法X-RAY DIFFRACTION (2.306 Å)
主引用文献Obstruction of Dengue Virus Maturation by Fab Fragments of the 2H2 Antibody.
J.Virol., 87, 2013
5B1C
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Crystal structure of DEN4 ED3 mutant with L387I
分子名称: Envelope protein E, SULFATE ION
著者Kulkarni, M.R, Numoto, N, Ito, N, Kuroda, Y.
登録日2015-12-02
公開日2016-02-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.003 Å)
主引用文献Modeling and experimental assessment of a buried Leu-Ile mutation in dengue envelope domain III
Biochem.Biophys.Res.Commun., 471, 2016
6H9R
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Dengue-RdRp3-inhibitor complex soaking
分子名称: 2-(4-methoxy-3-thiophen-2-yl-phenyl)ethanoic acid, DI(HYDROXYETHYL)ETHER, Genome polyprotein, ...
著者Talapatra, S.K, Kozielski, F.
登録日2018-08-05
公開日2019-03-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Development and validation of RdRp Screen, a crystallization screen for viral RNA-dependent RNA polymerases.
Biol Open, 8, 2019
7V3G
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DENV2_NGC_Fab_C10 28degrees (2Fab:3E)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, ...
著者Shu, B, Zhang, S, Victor, A.K, Ng, T.S, Lok, S.M.
登録日2021-08-10
公開日2021-12-29
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Human antibody C10 neutralizes by diminishing Zika but enhancing dengue virus dynamics.
Cell, 184, 2021
7V3H
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DENV2_NGC_Fab_C10 28degrees (3Fab:3E)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C10 IgG heavy chain variable region, ...
著者Shu, B, Zhang, S, Victor, A.K, Ng, T.S, Lok, S.M.
登録日2021-08-10
公開日2021-12-29
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Human antibody C10 neutralizes by diminishing Zika but enhancing dengue virus dynamics.
Cell, 184, 2021
7V3I
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DENV2_NGC_Fab_C10 4degrees (3Fab:3E)
分子名称: Envelope protein E, Fab_C10_heavy_chain, Fab_C10_light_chain, ...
著者Shu, B, Zhang, S, Victor, A.K, Ng, T.S, Lok, S.M.
登録日2021-08-10
公開日2021-12-29
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Human antibody C10 neutralizes by diminishing Zika but enhancing dengue virus dynamics.
Cell, 184, 2021
7LYF
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Dengue virus RNA promoter stem-loop A fused with tRNA-scaffold
分子名称: MAGNESIUM ION, RNA promoter stem-loop A fused with tRNA
著者Lee, E.H, Choi, K.H.
登録日2021-03-06
公開日2021-05-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structures of flavivirus RNA promoters suggest two binding modes with NS5 polymerase.
Nat Commun, 12, 2021
7V3F
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DENV2_NGC_Fab_C10 28degree (1Fab:3E)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, ...
著者Shu, B, Zhang, S, Victor, A.K, Ng, T.S, Lok, S.M.
登録日2021-08-10
公開日2021-12-29
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Human antibody C10 neutralizes by diminishing Zika but enhancing dengue virus dynamics.
Cell, 184, 2021
7V3J
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DENV2:F(ab')2-local
分子名称: Envelope protein E, Fab_C10_heavy_chain, Fab_C10_light_chain, ...
著者Shu, B, Zhang, S, Victor, A.K, Ng, T.S, Lok, S.M.
登録日2021-08-10
公開日2021-12-29
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Human antibody C10 neutralizes by diminishing Zika but enhancing dengue virus dynamics.
Cell, 184, 2021
2JLS
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BU of 2jls by Molmil
Dengue virus 4 NS3 helicase in complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
著者Luo, D.H, Xu, T, Watson, R.P, Becker, D.S, Sampath, A, Jahnke, W, Yeong, S.S, Wang, C.H, Lim, S.P, Vasudevan, S.G, Lescar, J.
登録日2008-09-15
公開日2008-11-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Insights Into RNA Unwinding and ATP Hydrolysis by the Flavivirus Ns3 Protein.
Embo J., 27, 2008
2JLU
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BU of 2jlu by Molmil
Dengue virus 4 NS3 helicase in complex with ssRNA
分子名称: 5'-R(*AP*GP*AP*CP*UP*AP*AP*CP*AP*AP*CP*U)-3', GLYCEROL, SERINE PROTEASE SUBUNIT NS3
著者Luo, D.H, Xu, T, Watson, R.P, Becker, D.S, Sampath, A, Jahnke, W, Yeong, S.S, Wang, C.H, Lim, S.P, Vasudevan, S.G, Lescar, J.
登録日2008-09-15
公開日2008-11-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Insights Into RNA Unwinding and ATP Hydrolysis by the Flavivirus Ns3 Protein.
Embo J., 27, 2008
2JLX
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Dengue virus 4 NS3 helicase in complex with ssRNA and ADP-Vanadate
分子名称: 5'-R(*AP*GP*AP*CP*UP*AP*AP*CP*AP*AP*CP*U)-3', ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ...
著者Luo, D.H, Xu, T, Watson, R.P, Becker, D.S, Sampath, A, Jahnke, W, Yeong, S.S, Wang, C.H, Lim, S.P, Vasudevan, S.G, Lescar, J.
登録日2008-09-15
公開日2008-11-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Insights Into RNA Unwinding and ATP Hydrolysis by the Flavivirus Ns3 Protein.
Embo J., 27, 2008
2JLW
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Dengue virus 4 NS3 helicase in complex with ssRNA2
分子名称: 5'-R(*UP*AP*GP*AP*CP*UP*AP*AP*CP*AP*AP*CP*U)-3', GLYCEROL, PHOSPHATE ION, ...
著者Luo, D.H, Xu, T, Watson, R.P, Becker, D.S, Sampath, A, Jahnke, W, Yeong, S.S, Wang, C.H, Lim, S.P, Vasudevan, S.G, Lescar, J.
登録日2008-09-15
公開日2008-11-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Insights Into RNA Unwinding and ATP Hydrolysis by the Flavivirus Ns3 Protein
Embo J., 27, 2008
2JLR
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Dengue virus 4 NS3 helicase in complex with AMPPNP
分子名称: MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SERINE PROTEASE SUBUNIT NS3
著者Luo, D.H, Xu, T, Watson, R.P, Becker, D.S, Sampath, A, Jahnke, W, Yeong, S.S, Wang, C.H, Lim, S.P, Vasudevan, S.G, Lescar, J.
登録日2008-09-15
公開日2008-11-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Insights Into RNA Unwinding and ATP Hydrolysis by the Flavivirus Ns3 Protein.
Embo J., 27, 2008
2JLY
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Dengue virus 4 NS3 helicase in complex with ssRNA and ADP-Phosphate
分子名称: 5'-R(*AP*GP*AP*CP*UP*AP*AP*CP*AP*AP*CP*U)-3', ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ...
著者Luo, D.H, Xu, T, Watson, R.P, Becker, D.S, Sampath, A, Jahnke, W, Yeong, S.S, Wang, C.H, Lim, S.P, Vasudevan, S.G, Lescar, J.
登録日2008-09-15
公開日2008-11-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Insights Into RNA Unwinding and ATP Hydrolysis by the Flavivirus Ns3 Protein.
Embo J., 27, 2008
2JLV
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Dengue virus 4 NS3 helicase in complex with ssRNA and AMPPNP
分子名称: 5'-R(*AP*GP*AP*CP*UP*AP*AP*CP*AP*AP*CP*U)-3', CHLORIDE ION, GLYCEROL, ...
著者Luo, D.H, Xu, T, Watson, R.P, Becker, D.S, Sampath, A, Jahnke, W, Yeong, S.S, Wang, C.H, Lim, S.P, Vasudevan, S.G, Lescar, J.
登録日2008-09-15
公開日2008-11-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Insights Into RNA Unwinding and ATP Hydrolysis by the Flavivirus Ns3 Protein
Embo J., 27, 2008
2JLQ
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Dengue virus 4 NS3 helicase structure, apo enzyme.
分子名称: CHLORIDE ION, GLYCEROL, SERINE PROTEASE SUBUNIT NS3
著者Luo, D.H, Xu, T, Watson, R.P, Becker, D.S, Sampath, A, Jahnke, W, Yeong, S.S, Wang, C.H, Lim, S.P, Vasudevan, S.G, Lescar, J.
登録日2008-09-15
公開日2008-11-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Insights Into RNA Unwinding and ATP Hydrolysis by the Flavivirus Ns3 Protein.
Embo J., 27, 2008

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