7V3H

DENV2_NGC_Fab_C10 28degrees (3Fab:3E)

Summary for 7V3H

• Entry DOI: 10.2210/pdb7v3h/pdb
• EMDB information: 31679
• Descriptor: Envelope protein E, Small envelope protein M, C10 IgG light chain variable region, ... (6 entities in total)
• Functional Keywords: complex, antibody, virus, virus-immune system complex, virus/immune system
• Biological source: Dengue virus type 2 (strain Thailand/NGS-C/1944) (DENV-2); More
• Total number of polymer chains: 12
• Total formula weight: 265614.64

Authors

Shu, B.,Zhang, S.,Victor, A.K.,Ng, T.S.,Lok, S.M. (deposition date: 2021-08-10, release date: 2021-12-29)

• Primary citation: Lim, X.X.,Shu, B.,Zhang, S.,Tan, A.W.K.,Ng, T.S.,Lim, X.N.,Chew, V.S.,Shi, J.,Screaton, G.R.,Lok, S.M.,Anand, G.S.; Human antibody C10 neutralizes by diminishing Zika but enhancing dengue virus dynamics.; Cell, 184:6067-6080.e13, 2021; PubMed: 34852238; DOI: 10.1016/j.cell.2021.11.009

Experimental method

ELECTRON MICROSCOPY (3.6 Å)