PDB: 42091 件ウェブページステータス検索Chemie searchBIRD

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1PK9	Crystal Structure of E. coli purine nucleoside phosphorylase complexed with 2-fluoroadenosine and sulfate/phosphate 分子名称: 2-(6-AMINO-2-FLUORO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type 著者 Bennett, E.M, Li, C, Allan, P.W, Parker, W.B, Ealick, S.E. 登録日 2003-06-05 公開日 2003-11-25 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase. J.Biol.Chem., 278, 2003
1PKE	Crystal Structure of E. coli purine nucleoside phosphorylase complexed with 2-fluoro-2'-deoxyadenosine and sulfate/phosphate 分子名称: 5-(6-AMINO-2-FLUORO-PURIN-9-YL)-2-HYDROXYMETHYL-TETRAHYDRO-FURAN-3-OL, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type 著者 Bennett, E.M, Li, C, Allan, P.W, Parker, W.B, Ealick, S.E. 登録日 2003-06-05 公開日 2003-11-25 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase. J.Biol.Chem., 278, 2003
1RCT	Crystal structure of Human purine nucleoside phosphorylase complexed with INOSINE 分子名称: INOSINE, Purine nucleoside phosphorylase, SULFATE ION 著者 Canduri, F, dos Santos, D.M, Silva, R.G, Mendes, M.A, Palma, M.S, de Azevedo Jr, W.F, Basso, L.A, Santos, D.S. 登録日 2003-11-04 公開日 2004-01-20 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structures of human purine nucleoside phosphorylase complexed with inosine and ddI Biochem.Biophys.Res.Commun., 313, 2004
1JYS	Crystal Structure of E. coli MTA/AdoHcy Nucleosidase 分子名称: ADENINE, MTA/SAH nucleosidase 著者 Lee, J.E, Cornell, K.A, Riscoe, M.K, Howell, P.L. 登録日 2001-09-13 公開日 2002-10-01 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of E. coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase reveals similarity to the purine nucleoside phosphorylases. Structure, 9, 2001
1NHV	Hepatitis C virus RNA polymerase in complex with non-nucleoside analogue inhibitor 分子名称: (2S)-2-[(5-BENZOFURAN-2-YL-THIOPHEN-2-YLMETHYL)-(2,4-DICHLORO-BENZOYL)-AMINO]-3-PHENYL-PROPIONIC ACID, HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE 著者 Wang, M, Ng, K.K.S, Cherney, M.M, Chan, L, Yannopoulos, C.G, Bedard, J, Morin, N, Nguyen-Ba, N, Alaoui-Ismaili, M.H, Bethell, R.C, James, M.N.G. 登録日 2002-12-19 公開日 2003-03-18 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Non-Nucleoside Analogue Inhibitors Bind to an Allosteric Site on HCV NS5B Polymerase: Crystal Structures and Mechanism of Inhibition J.Biol.Chem., 278, 2003
1NHU	Hepatitis C virus RNA polymerase in complex with non-nucleoside analogue inhibitor 分子名称: (2S)-2-[(2,4-DICHLORO-BENZOYL)-(3-TRIFLUOROMETHYL-BENZYL)-AMINO]-3-PHENYL-PROPIONIC ACID, HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE 著者 Wang, M, Ng, K.K.S, Cherney, M.M, Chan, L, Yannopoulos, C.G, Bedard, J, Morin, N, Nguyen-Ba, N, Alaoui-Ismaili, M.H, Bethell, R.C, James, M.N.G. 登録日 2002-12-19 公開日 2003-03-18 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Non-Nucleoside Analogue Inhibitors Bind to an Allosteric Site on HCV NS5B Polymerase: Crystal Structures and Mechanism of Inhibition J.Biol.Chem., 278, 2003
1K9S	PURINE NUCLEOSIDE PHOSPHORYLASE FROM E. COLI IN COMPLEX WITH FORMYCIN A DERIVATIVE AND PHOSPHATE 分子名称: 2-(7-AMINO-6-METHYL-3H-PYRAZOLO[4,3-D]PYRIMIDIN-3-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, 2-HYDROXYMETHYL-5-(7-METHYLAMINO-3H-PYRAZOLO[4,3-D]PYRIMIDIN-3-YL)-TETRAHYDRO-FURAN-3,4-DIOL, PHOSPHATE ION, ... 著者 Koellner, G, Bzowska, A, Wielgus-Kutrowska, B, Luic, M, Steiner, T, Saenger, W, Stepinski, J. 登録日 2001-10-30 公開日 2001-11-28 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Open and closed conformation of the E. coli purine nucleoside phosphorylase active center and implications for the catalytic mechanism. J.Mol.Biol., 315, 2002
1OT3	Crystal structure of Drosophila deoxyribonucleotide kinase complexed with the substrate deoxythymidine 分子名称: Deoxyribonucleoside Kinase, SULFATE ION, THYMIDINE 著者 Mikkelsen, N.E, Johansson, K, Karlsson, A, Knecht, W, Andersen, G, Piskur, J, Munch-Petersen, B, Eklund, H. 登録日 2003-03-21 公開日 2003-05-27 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Basis for Feedback Inhibition of the Deoxyribonucleoside Salvage Pathway: Studies of the Drosophila Deoxyribonucleoside Kinase. Biochemistry, 42, 2003
2D41	X-ray crystal structure of hepatitis C virus RNA-dependent RNA polymerase in complex with non-nucleoside inhibitor 分子名称: 5'-ACETYL-4-{[(2,4-DIMETHYLPHENYL)SULFONYL]AMINO}-2,2'-BITHIOPHENE-5-CARBOXYLIC ACID, polyprotein 著者 Biswal, B.K, Wang, M, Cherney, M.M, Chan, L, Yannopoulos, C.G, Bilimoria, D, Bedard, J, James, M.N.G. 登録日 2005-10-05 公開日 2006-08-01 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Non-nucleoside Inhibitors Binding to Hepatitis C Virus NS5B Polymerase Reveal a Novel Mechanism of Inhibition J.Mol.Biol., 361, 2006
2D3Z	X-ray crystal structure of hepatitis C virus RNA-dependent RNA polymerase in complex with non-nucleoside analogue inhibitor 分子名称: 5-(4-FLUOROPHENYL)-3-{[(4-METHYLPHENYL)SULFONYL]AMINO}THIOPHENE-2-CARBOXYLIC ACID, polyprotein 著者 Biswal, B.K, Wang, M, Cherney, M.M, Chan, L, Yannopoulos, C.G, Bilimoria, D, Bedard, J, James, M.N.G. 登録日 2005-10-04 公開日 2006-08-01 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Non-nucleoside Inhibitors Binding to Hepatitis C Virus NS5B Polymerase Reveal a Novel Mechanism of Inhibition J.Mol.Biol., 361, 2006
2D3U	X-ray crystal structure of hepatitis C virus RNA dependent RNA polymerase in complex with non-nucleoside analogue inhibitor 分子名称: 5-(4-CYANOPHENYL)-3-{[(2-METHYLPHENYL)SULFONYL]AMINO}THIOPHENE-2-CARBOXYLIC ACID, polyprotein 著者 Biswal, B.K, Wang, M, Cherney, M.M, Chan, L, Yannopoulos, C.G, Bilimoria, D, Bedard, J, James, M.N.G. 登録日 2005-10-02 公開日 2006-08-01 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Non-nucleoside Inhibitors Binding to Hepatitis C Virus NS5B Polymerase Reveal a Novel Mechanism of Inhibition J.Mol.Biol., 361, 2006
5KO6	Crystal Structure of Isoform 2 of Purine Nucleoside Phosphorylase from Schistosoma mansoni in complex with cytosine and ribose-1-phosphate 分子名称: 1-O-phosphono-alpha-D-ribofuranose, 6-AMINOPYRIMIDIN-2(1H)-ONE, Purine nucleoside phosphorylase 著者 Torini, J.R, Romanello, L, Bird, L, Owens, R, Brandao-Neto, J, Pereira, H.M. 登録日 2016-06-29 公開日 2017-08-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 The molecular structure of Schistosoma mansoni PNP isoform 2 provides insights into the nucleoside selectivity of PNPs. PLoS ONE, 13, 2018
1PBN	PURINE NUCLEOSIDE PHOSPHORYLASE 分子名称: PURINE NUCLEOSIDE PHOSPHORYLASE 著者 Mao, C, Ealick, S.E. 登録日 1995-07-10 公開日 1995-11-14 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Calf spleen purine nucleoside phosphorylase complexed with substrates and substrate analogues. Biochemistry, 37, 1998
3JCM	Cryo-EM structure of the spliceosomal U4/U6.U5 tri-snRNP 分子名称: 13 kDa ribonucleoprotein-associated protein, GUANOSINE-5'-TRIPHOSPHATE, N,N,7-trimethylguanosine 5'-(trihydrogen diphosphate), ... 著者 Wan, R, Yan, C, Bai, R, Wang, L, Huang, M, Wong, C.C, Shi, Y. 登録日 2015-12-23 公開日 2016-02-24 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 The 3.8 angstrom structure of the U4/U6.U5 tri-snRNP: Insights into spliceosome assembly and catalysis Science, 351, 2016
2BSX	Crystal structure of the Plasmodium falciparum purine nucleoside phosphorylase complexed with inosine 分子名称: INOSINE, PURINE NUCLEOSIDE PHOSPHORYLASE 著者 Schnick, C, Brzozowski, A.M, Dodson, E.J, Murshudov, G.N, Brannigan, J.A, Wilkinson, A.J. 登録日 2005-05-24 公開日 2005-08-18 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structures of Plasmodium Falciparum Purine Nucleoside Phosphorylase Complexed with Sulfate and its Natural Substrate Inosine Acta Crystallogr.,Sect.D, 61, 2005
2ON6	Crystal structure of human purine nucleoside phosphorylase mutant H257F with Imm-H 分子名称: 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, Purine nucleoside phosphorylase 著者 Rinaldo-Matthis, A, Murkin, A.S, Almo, S.C, Schramm, V.L. 登録日 2007-01-23 公開日 2007-05-22 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.503 Å) 主引用文献 Neighboring Group Participation in the Transition State of Human Purine Nucleoside Phosphorylase Biochemistry, 46, 2007
2OC4	Crystal structure of human purine nucleoside phosphorylase mutant H257D with Imm-H 分子名称: 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, PHOSPHATE ION, Purine nucleoside phosphorylase 著者 Rinaldo-Matthis, A, Almo, S.C, Schramm, V.L. 登録日 2006-12-20 公開日 2007-05-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.592 Å) 主引用文献 Neighboring Group Participation in the Transition State of Human Purine Nucleoside Phosphorylase Biochemistry, 46, 2007
2OC9	Crystal structure of human purine nucleoside phosphorylase mutant H257G with Imm-H 分子名称: 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, PHOSPHATE ION, Purine nucleoside phosphorylase 著者 Rinaldo-Matthis, A, Almo, S.C, Schramm, V.L. 登録日 2006-12-20 公開日 2007-05-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Neighboring Group Participation in the Transition State of Human Purine Nucleoside Phosphorylase Biochemistry, 46, 2007
2Q7O	Structure of human purine nucleoside phosphorylase in complex with L-Immucillin-H 分子名称: 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, PHOSPHATE ION, Purine nucleoside phosphorylase 著者 Rinaldo-Matthis, A, Almo, S.C, Schramm, V.L. 登録日 2007-06-07 公開日 2008-01-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 L-Enantiomers of transition state analogue inhibitors bound to human purine nucleoside phosphorylase. J.Am.Chem.Soc., 130, 2008
4D8Y	Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in space group P212121 at pH 5.6 分子名称: GLYCEROL, Purine nucleoside phosphorylase deoD-type, SULFATE ION 著者 Santos, C.R, Meza, A.N, Martins, N.H, Giuseppe, P.O, Murakami, M.T. 登録日 2012-01-11 公開日 2012-09-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
4D8X	Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in space group P6322 at pH 4.6 分子名称: Purine nucleoside phosphorylase deoD-type 著者 Santos, C.R, Meza, A.N, Martins, N.H, Giuseppe, P.O, Murakami, M.T. 登録日 2012-01-11 公開日 2012-09-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
4DA6	Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in complex with ganciclovir 分子名称: 9-(1,3-DIHYDROXY-PROPOXYMETHANE)GUANINE, CHLORIDE ION, DIMETHYL SULFOXIDE, ... 著者 Martins, N.H, Giuseppe, P.O, Meza, A.N, Murakami, M.T. 登録日 2012-01-12 公開日 2012-09-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
4D8V	Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis at pH 4.2 分子名称: ADENINE, Purine nucleoside phosphorylase deoD-type, SULFATE ION 著者 Santos, C.R, Meza, A.N, Martins, N.H, Giuseppe, P.O, Murakami, M.T. 登録日 2012-01-11 公開日 2012-09-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
4DA0	Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in complex with 2'-deoxyguanosine 分子名称: 2'-DEOXY-GUANOSINE, CHLORIDE ION, Purine nucleoside phosphorylase deoD-type 著者 Martins, N.H, Giuseppe, P.O, Meza, A.N, Murakami, M.T. 登録日 2012-01-12 公開日 2012-09-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
4D98	Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in space group H32 at pH 7.5 分子名称: CHLORIDE ION, GLYCEROL, Purine nucleoside phosphorylase deoD-type, ... 著者 Santos, C.R, Meza, A.N, Martins, N.H, Giuseppe, P.O, Murakami, M.T. 登録日 2012-01-11 公開日 2012-09-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012

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