Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

7YYN
DownloadVisualize
BU of 7yyn by Molmil
Mammalian Dicer in the dicing state with pre-miR-15a substrate
分子名称: 59-nt precursor of miR-15a, Isoform 2 of Endoribonuclease Dicer
著者Zanova, M, Zapletal, D, Kubicek, K, Stefl, R, Pinkas, M, Novacek, J.
登録日2022-02-18
公開日2022-11-16
実験手法ELECTRON MICROSCOPY (6.21 Å)
主引用文献Structural and functional basis of mammalian microRNA biogenesis by Dicer.
Mol.Cell, 82, 2022
7ZPI
DownloadVisualize
BU of 7zpi by Molmil
Mammalian Dicer in the "dicing state" with pre-miR-15a substrate
分子名称: 59-nt precursor of miR-15a, Endoribonuclease Dicer
著者Zanova, M, Zapletal, D, Kubicek, K, Stefl, R, Pinkas, M, Novacek, J.
登録日2022-04-27
公開日2022-11-16
実験手法ELECTRON MICROSCOPY (5.91 Å)
主引用文献Structural and functional basis of mammalian microRNA biogenesis by Dicer.
Mol.Cell, 82, 2022
1ZBH
DownloadVisualize
BU of 1zbh by Molmil
3'-end specific recognition of histone mRNA stem-loop by 3'-exonuclease
分子名称: 3'-5' exonuclease ERI1, 5'-R(*CP*CP*GP*GP*CP*UP*CP*UP*UP*UP*UP*CP*AP*GP*AP*GP*CP*CP*GP*G)-3', ADENOSINE MONOPHOSPHATE, ...
著者Cheng, Y, Patel, D.J.
登録日2005-04-08
公開日2006-09-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for 3'-end specific recognition of histone mRNA stem-loop by 3'-exonuclease, a human nuclease that also targets siRNA
To be Published
1ZBU
DownloadVisualize
BU of 1zbu by Molmil
crystal structure of full-length 3'-exonuclease
分子名称: 3'-5' exonuclease ERI1, ADENOSINE MONOPHOSPHATE, MAGNESIUM ION
著者Cheng, Y, Patel, D.J.
登録日2005-04-08
公開日2006-09-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.998 Å)
主引用文献Structural basis for 3'-end specific recognition of histone mRNA stem-loop by 3'-exonuclease, a human nuclease that also targets siRNA
To be Published
4RBY
DownloadVisualize
BU of 4rby by Molmil
First X-ray structure of RNA containing guanosine phosphorodithioate
分子名称: 5'-R(*CP*GP*CP*(2SG)P*AP*AP*UP*UP*AP*GP*CP*G)-3', STRONTIUM ION
著者Pallan, P.S, Egli, M.
登録日2014-09-13
公開日2015-09-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献Crystal Structure, Stability and siRNA Activity of Phosphorodithioate-Modified RNAs
To be Published
4RC0
DownloadVisualize
BU of 4rc0 by Molmil
X-ray structure of RNA containing guanosine phosphorodithioate
分子名称: 5'-R(*CP*GP*CP*GP*AP*AP*UP*UP*(A2M)P*(2SG)P*CP*G)-3'
著者Pallan, P.S, Egli, M.
登録日2014-09-13
公開日2015-09-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.13 Å)
主引用文献Crystal Structure, Stability and siRNA Activity of Phosphorodithioate-Modified RNAs
To be Published
4RBZ
DownloadVisualize
BU of 4rbz by Molmil
X-ray structure of RNA containing adenosine phosphorodithioate
分子名称: 5'-R(*CP*GP*CP*GP*(A2M)P*(ADS)P*UP*UP*AP*GP*CP*G)-3'
著者Pallan, P.S, Egli, M.
登録日2014-09-13
公開日2015-09-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.18 Å)
主引用文献Crystal Structure, Stability and siRNA Activity of Phosphorodithioate-Modified RNAs
To be Published
4O41
DownloadVisualize
BU of 4o41 by Molmil
Amide linked RNA
分子名称: AMIDE LINKED RNA, STRONTIUM ION
著者Pallan, P.S, Egli, M.
登録日2013-12-18
公開日2014-07-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Amides are excellent mimics of phosphate internucleoside linkages and are well tolerated in short interfering RNAs.
Nucleic Acids Res., 42, 2014
2X1O
DownloadVisualize
BU of 2x1o by Molmil
Gelsolin Nanobody
分子名称: GELSOLIN NANOBODY
著者Van Den Abbeele, A, Declercq, S, De Ganck, A, De Corte, V, Van Loo, B, Srinivasan, V, Steyaert, J, Van De Kerckhove, J, Gettemans, J.
登録日2010-01-03
公開日2011-01-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献A Llama-Derived Gelsolin Single-Domain Antibody Blocks Gelsolin-G-Actin Interaction.
Cell.Mol.Life Sci., 67, 2010
2X1P
DownloadVisualize
BU of 2x1p by Molmil
Gelsolin Nanobody
分子名称: GELSOLIN NANOBODY
著者Van Den Abbeele, A, Declercq, S, De Ganck, A, De Corte, V, Van Loo, B, Srinivasan, V, Steyaert, J, Van De Kerckhove, J, Gettemans, J.
登録日2010-01-03
公開日2011-01-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献A Llama-Derived Gelsolin Single-Domain Antibody Blocks Gelsolin-G-Actin Interaction.
Cell.Mol.Life Sci., 67, 2010
2X1Q
DownloadVisualize
BU of 2x1q by Molmil
Gelsolin Nanobody
分子名称: GELSOLIN NANOBODY
著者Van Den Abbeele, A, Declercq, S, De Ganck, A, De Corte, V, Van Loo, B, Srinivasan, V, Steyaert, J, Van De Kerckhove, J, Gettemans, J.
登録日2010-01-03
公開日2011-01-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.06 Å)
主引用文献A Llama-Derived Gelsolin Single-Domain Antibody Blocks Gelsolin-G-Actin Interaction.
Cell.Mol.Life Sci., 67, 2010
3TIX
DownloadVisualize
BU of 3tix by Molmil
Crystal structure of the Chp1-Tas3 complex core
分子名称: CHLORIDE ION, Chromo domain-containing protein 1, POTASSIUM ION, ...
著者Schalch, T, Joshua-Tor, L.
登録日2011-08-22
公開日2011-11-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.9001 Å)
主引用文献The Chp1-Tas3 core is a multifunctional platform critical for gene silencing by RITS.
Nat.Struct.Mol.Biol., 18, 2011
6WXQ
DownloadVisualize
BU of 6wxq by Molmil
Crystal structure of CRISPR-associated transcription factor Csa3 complexed with cA4
分子名称: CRISPR-associated transcription factor Csa3 (Type I-A), GLYCEROL, cyclic tetraadenylate
著者Xia, P, Dutta, A, Parashar, V.
登録日2020-05-11
公開日2021-11-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural basis of cyclic oligoadenylate binding to the transcription factor Csa3 outlines cross talk between type III and type I CRISPR systems.
J.Biol.Chem., 298, 2022
1YTU
DownloadVisualize
BU of 1ytu by Molmil
Structural basis for 5'-end-specific recognition of the guide RNA strand by the A. fulgidus PIWI protein
分子名称: 5'-R(P*AP*GP*AP*CP*AP*G)-3', 5'-R(P*UP*GP*UP*C)-3', MAGNESIUM ION, ...
著者Ma, J.B, Yuan, Y.R, Meister, G, Pei, Y, Tuschl, T, Patel, D.J.
登録日2005-02-11
公開日2005-04-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein.
Nature, 434, 2005
4WYQ
DownloadVisualize
BU of 4wyq by Molmil
Crystal structure of the Dicer-TRBP interface
分子名称: Endoribonuclease Dicer, Poly(UNK), RISC-loading complex subunit TARBP2
著者Wilson, R.C, Doudna, J.A.
登録日2014-11-18
公開日2014-12-17
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Dicer-TRBP Complex Formation Ensures Accurate Mammalian MicroRNA Biogenesis.
Mol.Cell, 57, 2015
4OLB
DownloadVisualize
BU of 4olb by Molmil
Crystal Structure of Human Argonaute2 Bound to Tryptophan
分子名称: 5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*U)-3', Protein argonaute-2, TRYPTOPHAN
著者Schirle, N.T, MacRae, I.J.
登録日2014-01-23
公開日2014-02-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.899 Å)
主引用文献The crystal structure of human Argonaute2.
Science, 336, 2012
4OLA
DownloadVisualize
BU of 4ola by Molmil
Crystal Structure of Human Argonaute2
分子名称: 5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*U)-3', ISOPROPYL ALCOHOL, PHENOL, ...
著者Schirle, N.T, MacRae, I.J.
登録日2014-01-23
公開日2014-02-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The crystal structure of human Argonaute2.
Science, 336, 2012
5JRE
DownloadVisualize
BU of 5jre by Molmil
Crystal structure of NeC3PO in complex with ssDNA.
分子名称: 9-METHYL-9H-PURIN-6-AMINE, ADENINE, NEQ131, ...
著者Gan, J, Zhang, J.
登録日2016-05-06
公開日2016-09-28
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for single-stranded RNA recognition and cleavage by C3PO
Nucleic Acids Res., 44, 2016
5JRC
DownloadVisualize
BU of 5jrc by Molmil
Crystal structure of NeC3PO in complex with ssRNA.
分子名称: CALCIUM ION, NEQ131, ssRNA
著者Zhang, J, Gan, J.
登録日2016-05-06
公開日2016-09-28
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for single-stranded RNA recognition and cleavage by C3PO
Nucleic Acids Res., 44, 2016
5JR9
DownloadVisualize
BU of 5jr9 by Molmil
Crystal structure of apo-NeC3PO
分子名称: NEQ131
著者Zhang, J, Gan, J.
登録日2016-05-06
公開日2016-09-28
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for single-stranded RNA recognition and cleavage by C3PO
Nucleic Acids Res., 44, 2016
5W6V
DownloadVisualize
BU of 5w6v by Molmil
The Structure of human Argonaute-1 in complex with the hook motif of human GW182
分子名称: Protein argonaute-1, RNA (5'-R(P*AP*AP*UP*AP*UP*UP*AP*AP*AP*A)-3'), Trinucleotide repeat-containing gene 6A protein
著者Elkayam, E, Faehnle, C.R, Joshua-Tor, L.
登録日2017-06-17
公開日2017-07-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.828 Å)
主引用文献Multivalent Recruitment of Human Argonaute by GW182.
Mol. Cell, 67, 2017
7Y8P
DownloadVisualize
BU of 7y8p by Molmil
Crystal structure of 4'-selenoRNA duplex
分子名称: COBALT HEXAMMINE(III), RNA (5'-R(*GP*GP*AP*(IKS)P*(ILK)P*(IKS)P*GP*AP*GP*UP*CP*C)-3')
著者Kondo, J, Minakawa, N, Ohta, M, Takahashi, H, Tarashima, N.
登録日2022-06-24
公開日2023-05-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Synthesis and properties of fully-modified 4'-selenoRNA, an endonuclease-resistant RNA analog.
Bioorg.Med.Chem., 76, 2022
4TXD
DownloadVisualize
BU of 4txd by Molmil
Crystal structure of Thermofilum pendens Csc2
分子名称: Csc2, ZINC ION
著者Hrle, A, Conti, E.
登録日2014-07-03
公開日2014-08-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.818 Å)
主引用文献Structural analyses of the CRISPR protein Csc2 reveal the RNA-binding interface of the type I-D Cas7 family.
Rna Biol., 11, 2014
3VEM
DownloadVisualize
BU of 3vem by Molmil
Structural basis of transcriptional gene silencing mediated by Arabidopsis MOM1
分子名称: Helicase protein MOM1
著者Nishikura, T, Petty, T.J, Halazonetis, T, Paszkowski, J, Thore, S.
登録日2012-01-09
公開日2012-03-07
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural Basis of Transcriptional Gene Silencing Mediated by Arabidopsis MOM1.
PLOS GENET., 8, 2012
3PJA
DownloadVisualize
BU of 3pja by Molmil
Crystal structure of human C3PO complex
分子名称: Translin, Translin-associated protein X
著者Huang, N, Zhang, H.
登録日2010-11-09
公開日2011-05-11
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of C3PO and mechanism of human RISC activation.
Nat.Struct.Mol.Biol., 18, 2011

220760

件を2024-06-05に公開中

PDB statisticsPDBj update infoContact PDBjnumon