5XBL
 
 | | Structure of nuclease in complex with associated protein | | 分子名称: | Associated protein, CRISPR-associated endonuclease Cas9/Csn1, RNA (98-MER) | | 著者 | Dong, D, Guo, M, Wang, S, Zhu, Y, Huang, Z. | | 登録日 | 2017-03-20 | | 公開日 | 2017-06-14 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (3.052 Å) | | 主引用文献 | Structural basis of CRISPR-SpyCas9 inhibition by an anti-CRISPR protein
Nature, 546, 2017
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3EQW
 | | A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine BSU-6042 in small unit cell | | 分子名称: | 3,6-Bis{3-[(2R)-(2-ethylpiperidino)]propionamido}acridine, 5'-D(*DGP*DGP*DGP*DGP*DTP*DTP*DTP*DTP*DGP*DGP*DGP*DG)-3', POTASSIUM ION | | 著者 | Campbell, N.H, Parkinson, G, Neidle, S. | | 登録日 | 2008-10-01 | | 公開日 | 2008-10-14 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Selectivity in Ligand Recognition of G-Quadruplex Loops.
Biochemistry, 48, 2009
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4XJE
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5FV0
 | | The cytoplasmic domain of EssC | | 分子名称: | 3'-O-[2-(METHYLAMINO)BENZOYL]ADENOSINE 5'-(TETRAHYDROGEN TRIPHOSPHATE), ADENOSINE-5'-TRIPHOSPHATE, ESX secretion system protein EccC, ... | | 著者 | Zoltner, M, Ng, W.M.A.V, Palmer, T, Hunter, W.N. | | 登録日 | 2016-02-01 | | 公開日 | 2016-03-02 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | | 主引用文献 | EssC: domain structures inform on the elusive translocation channel in the Type VII secretion system.
Biochem. J., 473, 2016
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5YDD
 | | Crystal structure of C-terminal domain of Rv1828 from Mycobacterium tuberculosis | | 分子名称: | (6R,8S,9S)-8-(hydroxymethyl)-6,11,11-tris(oxidanyl)-9-propyl-dodecanoic acid, GLYCEROL, SODIUM ION, ... | | 著者 | Singh, S, Karthiekeyan, S. | | 登録日 | 2017-09-12 | | 公開日 | 2018-09-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Characteristics of the essential pathogenicity factor Rv1828, a MerR family transcription regulator from Mycobacterium tuberculosis.
FEBS J., 285, 2018
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5EKG
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5EV1
 | | Structure I of Intact U2AF65 Recognizing a 3' Splice Site Signal | | 分子名称: | DI(HYDROXYETHYL)ETHER, DNA/RNA (5'-R(*UP*UP*U)-D(P*UP*UP*(BRU)P*U)-R(P*UP*U)-3'), SODIUM ION, ... | | 著者 | Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L. | | 登録日 | 2015-11-19 | | 公開日 | 2016-02-24 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.037 Å) | | 主引用文献 | An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal.
Nat Commun, 7, 2016
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5EV2
 | | Structure II of Intact U2AF65 Recognizing the 3' Splice Site Signal | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, DI(HYDROXYETHYL)ETHER, DNA (5'-R(P*UP*U)-D(P*UP*U)-R(P*U)-D(P*UP*(BRU)P*U)-3'), ... | | 著者 | Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L. | | 登録日 | 2015-11-19 | | 公開日 | 2016-02-24 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal.
Nat Commun, 7, 2016
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5YDC
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1YAG
 | | STRUCTURE OF THE YEAST ACTIN-HUMAN GELSOLIN SEGMENT 1 COMPLEX | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, MAGNESIUM ION, ... | | 著者 | Vorobiev, S, Strokopytov, B, Frieden, C, Almo, S.C. | | 登録日 | 1998-10-09 | | 公開日 | 1999-10-09 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The structure of nonvertebrate actin: Implications for the ATP
hydrolytic mechanism
Proc.Natl.Acad.Sci.USA, 100, 2003
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8FMF
 | | Structure of CBASS Cap5 from Pseudomonas syringae as an activated tetramer with the cyclic dinucleotide 3'2'-c-diAMP ligand (1 tetramer in the AU) | | 分子名称: | Cyclic (adenosine-(2'-5')-monophosphate-adenosine-(3'-5')-monophosphate, GLYCEROL, HEXAETHYLENE GLYCOL, ... | | 著者 | Rechkoblit, O, Kreitler, D.F, Aggarwal, A.K. | | 登録日 | 2022-12-23 | | 公開日 | 2024-02-07 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Activation of CBASS Cap5 endonuclease immune effector by cyclic nucleotides.
Nat.Struct.Mol.Biol., 31, 2024
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8FM1
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8FMG
 | | Structure of CBASS Cap5 from Pseudomonas syringae as an activated tetramer with the cyclic dinucleotide 3'2'-c-diAMP ligand (3 tetramers in the AU) | | 分子名称: | Cyclic (adenosine-(2'-5')-monophosphate-adenosine-(3'-5')-monophosphate, MAGNESIUM ION, SAVED domain-containing protein, ... | | 著者 | Rechkoblit, O, Kreitler, D.F, Aggarwal, A.K. | | 登録日 | 2022-12-23 | | 公開日 | 2024-02-07 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Activation of CBASS Cap5 endonuclease immune effector by cyclic nucleotides.
Nat.Struct.Mol.Biol., 31, 2024
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8FMH
 | | Structure of CBASS Cap5 from Pseudomonas syringae as an activated tetramer with the cyclic dinucleotide 3'2'-c-dGAMP ligand (2 tetramers in the AU) | | 分子名称: | 3'2'-cGAMP, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Rechkoblit, O, Kreitler, D.F, Aggarwal, A.K. | | 登録日 | 2022-12-23 | | 公開日 | 2024-02-07 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Activation of CBASS Cap5 endonuclease immune effector by cyclic nucleotides.
Nat.Struct.Mol.Biol., 31, 2024
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5WQD
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8DGC
 | | Avs3 bound to phage PhiV-1 terminase | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, SeAvs3, ... | | 著者 | Wilkinson, M.E, Gao, L, Strecker, J, Makarova, K.S, Macrae, R.K, Koonin, E.V, Zhang, F. | | 登録日 | 2022-06-23 | | 公開日 | 2022-08-03 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Prokaryotic innate immunity through pattern recognition of conserved viral proteins.
Science, 377, 2022
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3DU8
 | | Crystal structure of GSK-3 beta in complex with NMS-869553A | | 分子名称: | (7S)-2-(2-aminopyrimidin-4-yl)-7-(2-fluoroethyl)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one, Glycogen synthase kinase-3 beta | | 著者 | Bossi, R.T. | | 登録日 | 2008-07-17 | | 公開日 | 2009-03-03 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | First Cdc7 kinase inhibitors: pyrrolopyridinones as potent and orally active antitumor agents. 2. Lead discovery.
J.Med.Chem., 52, 2009
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1U2Z
 | | Crystal structure of histone K79 methyltransferase Dot1p from yeast | | 分子名称: | Histone-lysine N-methyltransferase, H3 lysine-79 specific, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Sawada, K, Yang, Z, Horton, J.R, Collins, R.E, Zhang, X, Cheng, X. | | 登録日 | 2004-07-20 | | 公開日 | 2004-09-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of the conserved core of the yeast Dot1p, a nucleosomal histone H3 lysine 79 methyltransferase
J.Biol.Chem., 279, 2004
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8DFS
 | | type I-C Cascade bound to AcrIF2 | | 分子名称: | Anti-CRISPR protein 30, CRISPR-associated protein, CT1133 family, ... | | 著者 | O'Brien, R.E, Bravo, J.P.K, Ramos, D, Hibshman, G.N, Wright, J.T, Taylor, D.W. | | 登録日 | 2022-06-22 | | 公開日 | 2023-02-22 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural snapshots of R-loop formation by a type I-C CRISPR Cascade.
Mol.Cell, 83, 2023
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8DFO
 | | type I-C Cascade bound to AcrIC4 | | 分子名称: | AcrIC4, CRISPR-associated protein, CT1133 family, ... | | 著者 | O'Brien, R.E, Bravo, J.P.K, Ramos, D, Hibshman, G.N, Wright, J.T, Taylor, D.W. | | 登録日 | 2022-06-22 | | 公開日 | 2023-02-15 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural snapshots of R-loop formation by a type I-C CRISPR Cascade.
Mol.Cell, 83, 2023
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8DEX
 | | type I-C Cascade | | 分子名称: | CRISPR-associated protein, CT1133 family, TM1801 family, ... | | 著者 | O'Brien, R.E, Bravo, J.P.K, Ramos, D, Hibshman, G.N, Wright, J.T, Taylor, D.W. | | 登録日 | 2022-06-21 | | 公開日 | 2023-02-15 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structural snapshots of R-loop formation by a type I-C CRISPR Cascade.
Mol.Cell, 83, 2023
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1ZJE
 | | 12mer-spd | | 分子名称: | 5'-D(*AP*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*T)-3', 5'-D(*TP*AP*GP*CP*CP*CP*CP*GP*CP*CP*CP*C)-3' | | 著者 | Dohm, J.A, Hsu, M.H, Hwu, J.R, Huang, R.C, Moudrianakis, E.N, Lattman, E.E, Gittis, A.G. | | 登録日 | 2005-04-28 | | 公開日 | 2005-05-10 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Influence of Ions, Hydration, and the Transcriptional Inhibitor P4N on the Conformations of the Sp1 Binding Site.
J.Mol.Biol., 349, 2005
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3N4S
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3N4R
 | | Structure of Csm1 C-terminal domain, R3 form | | 分子名称: | MALONATE ION, Monopolin complex subunit CSM1, PENTAETHYLENE GLYCOL | | 著者 | Corbett, K.D, Harrison, S.C. | | 登録日 | 2010-05-22 | | 公開日 | 2010-09-01 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.602 Å) | | 主引用文献 | The Monopolin Complex Crosslinks Kinetochore Components to Regulate Chromosome-Microtubule Attachments.
Cell(Cambridge,Mass.), 142, 2010
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4ZLX
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