8FMH

Structure of CBASS Cap5 from Pseudomonas syringae as an activated tetramer with the cyclic dinucleotide 3'2'-c-dGAMP ligand (2 tetramers in the AU)

Summary for 8FMH

• Entry DOI: 10.2210/pdb8fmh/pdb
• Descriptor: SAVED domain-containing protein, 3'2'-cGAMP, ZINC ION, ... (8 entities in total)
• Functional Keywords: cyclic dinucleotide, bacterial immunity, cbass, cap5 effector dna endonuclease, viral defense, immune system
• Biological source: Pseudomonas syringae
• Total number of polymer chains: 8
• Total formula weight: 348663.90

Authors

Rechkoblit, O.,Kreitler, D.F.,Aggarwal, A.K. (deposition date: 2022-12-23, release date: 2024-02-07, Last modification date: 2024-02-21)

• Primary citation: Rechkoblit, O.,Sciaky, D.,Kreitler, D.F.,Buku, A.,Kottur, J.,Aggarwal, A.K.; Activation of CBASS Cap5 endonuclease immune effector by cyclic nucleotides.; Nat.Struct.Mol.Biol., 2024; PubMed: 38321146; DOI: 10.1038/s41594-024-01220-x

Experimental method

X-RAY DIFFRACTION (1.87 Å)