PDB: 9904 件ウェブページステータス検索Chemie searchBIRD

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7S5Q	Crystal structure of SARS-CoV-2 B.1.351 variant receptor binding domain in complex with neutralizing antibodies CS44 and COVA1-16 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, COVA1-16 Heavy chain, ... 著者 Yuan, M, Wilson, I.A. 登録日 2021-09-11 公開日 2022-03-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.88 Å) 主引用文献 SARS-CoV-2 Beta variant infection elicits potent lineage-specific and cross-reactive antibodies. Science, 375, 2022
7S5R	Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibodies CV07-287 and COVA1-16 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, COVA1-16 Heavy chain, ... 著者 Yuan, M, Wilson, I.A. 登録日 2021-09-11 公開日 2022-03-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 SARS-CoV-2 Beta variant infection elicits potent lineage-specific and cross-reactive antibodies. Science, 375, 2022
5MU0	ACC1 Fab fragment in complex with citrullinated C1 epitope of CII (IA03) 分子名称: IA03 peptide containing the citrullinated C1 epitope of collagen type II,Collagen alpha-1(II) chain,IA03 peptide containing the citrullinated C1 epitope of collagen type II, heavy chain of ACC1 antibody Fab fragment, light chain of ACC1 antibody Fab fragment 著者 Dobritzsch, D, Holmdahl, R, Ge, C. 登録日 2017-01-11 公開日 2017-07-19 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage. JCI Insight, 2, 2017
7BNV	Crystal Structure of the SARS-CoV-2 Receptor Binding Domain in Complex with Antibody ION-300 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy Chain, Light Chain, ... 著者 Hall, G, Cowan, R, Carr, M. 登録日 2021-01-22 公開日 2021-11-17 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Cross-Reactive SARS-CoV-2 Neutralizing Antibodies From Deep Mining of Early Patient Responses. Front Immunol, 12, 2021
8K0C	Cryo-EM structure of conformation 1 of complex of Nipah virus attachment glycoprotein G with 1E5 neutralizing antibody 分子名称: Glycoprotein G, Heavy chain of 1E5 Fab fragments, Light chain of 1E5 Fab fragments 著者 Sun, M.M. 登録日 2023-07-08 公開日 2024-05-01 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.18 Å) 主引用文献 A potent Henipavirus cross-neutralizing antibody reveals a dynamic fusion-triggering pattern of the G-tetramer. Nat Commun, 15, 2024
8K0D	Cryo-EM structure of conformation 2 of complex of Nipah virus attachment G with 1E5 neutralizing antibody 分子名称: Glycoprotein G, The heavy chain of 1E5, The light chain of 1E5 著者 Sun, M. 登録日 2023-07-08 公開日 2024-05-01 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (2.94 Å) 主引用文献 A potent Henipavirus cross-neutralizing antibody reveals a dynamic fusion-triggering pattern of the G-tetramer. Nat Commun, 15, 2024
3J2Y	Electron Cryo-microscopy of Chikungunya VLP in complex with neutralizing antibody Fab 9.8B 分子名称: 9.8B heavy chain, 9.8B light chain 著者 Sun, S, Xiang, Y, Rossmann, M.G. 登録日 2013-01-28 公開日 2013-04-24 最終更新日 2018-07-18 実験手法 ELECTRON MICROSCOPY (14.9 Å) 主引用文献 Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization. Elife, 2, 2013
5MV4	ACC1 Fab fragment in complex with citrullinated CII616-639 epitope of collagen type II (ptm23) 分子名称: ACC1 antibody Fab fragment, heavy chain, light chain, ... 著者 Dobritzsch, D, Holmdahl, R, Ge, C. 登録日 2017-01-15 公開日 2017-07-19 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage. JCI Insight, 2, 2017
4O51	Crystal structure of the QAA variant of anti-hinge rabbit antibody 2095-2 in complex with IDES hinge peptide 分子名称: IDES hinge peptide, QAA-2095-2 heavy chain, QAA-2095-2 light chain 著者 Malia, T.J, Luo, J, Teplyakov, A, Gilliland, G.L. 登録日 2013-12-19 公開日 2014-03-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.204 Å) 主引用文献 Structure and specificity of an antibody targeting a proteolytically cleaved IgG hinge. Proteins, 82, 2014
4O4Y	Crystal structure of the anti-hinge rabbit antibody 2095-2 in complex with IDES hinge peptide 分子名称: 2095-2 heavy chain, 2095-2 light chain, GLYCEROL, ... 著者 Malia, T.J, Teplyakov, A, Luo, J, Gilliland, G.L. 登録日 2013-12-19 公開日 2014-03-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure and specificity of an antibody targeting a proteolytically cleaved IgG hinge. Proteins, 82, 2014
7EAM	immune complex of SARS-CoV-2 RBD and cross-neutralizing antibody 7D6 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, ... 著者 Li, T.T, Gu, Y, Li, S.W. 登録日 2021-03-07 公開日 2021-03-17 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Cross-neutralizing antibodies bind a SARS-CoV-2 cryptic site and resist circulating variants. Nat Commun, 12, 2021
5FUC	Biophysical and cellular characterisation of a junctional epitope antibody that locks IL-6 and gp80 together in a stable complex: implications for new therapeutic strategies 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, INTERLEUKIN-6, INTERLEUKIN-6 RECEPTOR SUBUNIT ALPHA, ... 著者 Adams, R, Griffin, R, Doyle, C, Ettorre, A. 登録日 2016-01-25 公開日 2017-01-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Discovery of a junctional epitope antibody that stabilizes IL-6 and gp80 protein:protein interaction and modulates its downstream signaling. Sci Rep, 7, 2017
7FEI	Complex of FMDV A/WH/CHA/09 and bovine neutralizing scFv antibody R55 分子名称: Capsid protein VP0, IG HEAVY CHAIN VARIABLE REGION, IG LAMDA CHAIN VARIABLE REGION 著者 He, Y, Li, K, Lou, Z. 登録日 2021-07-20 公開日 2021-09-29 最終更新日 2022-02-16 実験手法 ELECTRON MICROSCOPY (3.91 Å) 主引用文献 Structures of Foot-and-Mouth Disease Virus with Bovine Neutralizing Antibodies Reveal the Determinant of Intraserotype Cross-Neutralization. J.Virol., 95, 2021
6KZ0	HRV14 3C in complex with single chain antibody GGVV 分子名称: GGVV H chain, GGVV L chain, Genome polyprotein 著者 Meng, B, Yang, B, Wilson, I.A. 登録日 2019-09-21 公開日 2020-05-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Inhibitory antibodies identify unique sites of therapeutic vulnerability in rhinovirus and other enteroviruses. Proc.Natl.Acad.Sci.USA, 117, 2020
7E39	SARS-CoV-2 spike in complex with the Ab4 neutralizing antibody (State 3) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy Chain of Ab4, Light Chain of Ab4, ... 著者 Liu, C. 登録日 2021-02-08 公開日 2021-09-01 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Three epitope-distinct human antibodies from RenMab mice neutralize SARS-CoV-2 and cooperatively minimize the escape of mutants. Cell Discov, 7, 2021
7E3B	SARS-Cov-2 spike in complex with the Ab5 neutralizing antibody (focused refinement on Fab-RBD) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy Chain of Ab5, Light Chain of Ab5, ... 著者 Liu, C. 登録日 2021-02-08 公開日 2021-09-01 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Three epitope-distinct human antibodies from RenMab mice neutralize SARS-CoV-2 and cooperatively minimize the escape of mutants. Cell Discov, 7, 2021
7E3C	SARS-CoV-2 spike in complex with the Ab1 neutralizing antibody (focused refinement on Fab-RBD) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Ab1, Light chain of Ab1, ... 著者 Liu, C. 登録日 2021-02-08 公開日 2021-09-01 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Three epitope-distinct human antibodies from RenMab mice neutralize SARS-CoV-2 and cooperatively minimize the escape of mutants. Cell Discov, 7, 2021
5EWI	Crystal Structure of the Human Fab VRC38.01, an HIV-1 V1V2-Directed Neutralizing Antibody Isolated from Donor N90 分子名称: VRC38.01 Heavy Chain, VRC38.01 Light Chain 著者 Gorman, J, Kwong, P.D. 登録日 2015-11-20 公開日 2016-11-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.5996 Å) 主引用文献 Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop. Immunity, 46, 2017
4G6A	Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the broadly neutralizing antibody AP33 分子名称: AP33 Heavy Chain, AP33 Light chain, E2 peptide 著者 Kong, L, Wilson, I.A, Law, M. 登録日 2012-07-18 公開日 2012-09-26 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.501 Å) 主引用文献 Structure of Hepatitis C Virus Envelope Glycoprotein E2 Antigenic Site 412 to 423 in Complex with Antibody AP33. J.Virol., 86, 2012
4POU	VHH-metal in Complex with RNase A 分子名称: Ribonuclease pancreatic, VHH Antibody 著者 Fanning, S.W, Walter, R, Horn, J.R. 登録日 2014-02-26 公開日 2014-09-24 最終更新日 2014-10-22 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural basis of an engineered dual-specific antibody: conformational diversity leads to a hypervariable loop metal-binding site. Protein Eng.Des.Sel., 27, 2014
5GMQ	Structure of MERS-CoV RBD in complex with a fully human antibody MCA1 分子名称: 1,2-ETHANEDIOL, MCA1 heavy chain, MCA1 light chain, ... 著者 Chen, C, Wang, J.M, Zou, T.T, Gao, X.P, Cui, S, Jin, Q. 登録日 2016-07-15 公開日 2017-05-31 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.703 Å) 主引用文献 Human Neutralizing Monoclonal Antibody Inhibition of Middle East Respiratory Syndrome Coronavirus Replication in the Common Marmoset. J. Infect. Dis., 215, 2017
6N7U	apo-BDBV223 Fab 分子名称: BDBV223 antibody heavy chain, BDBV223 antibody light chain 著者 King, L.B, West, B.R, Saphire, E.O. 登録日 2018-11-28 公開日 2019-03-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Cross-reactive neutralizing human survivor monoclonal antibody BDBV223 targets the ebolavirus stalk. Nat Commun, 10, 2019
5F89	Structure of the Unliganded Fab from HIV-1 Neutralising Antibody CAP248-2B that Binds to the gp120 C-terminus - gp41 Interface 分子名称: CAP248-2B Heavy Chain, CAP248-2B Light Chain 著者 Wibmer, C.K, Gorman, J, Kwong, P.D. 登録日 2015-12-09 公開日 2016-12-21 最終更新日 2017-03-29 実験手法 X-RAY DIFFRACTION (2.7842 Å) 主引用文献 Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape. PLoS Pathog., 13, 2017
4NKM	Crystal structure of engineered anti-EE scFv antibody fragment 分子名称: Engineered scFv 著者 Kalyoncu, S, Hyun, J, Pai, J.C, Johnson, J.L, Etzminger, K, Jain, A, Heaner Jr, D, Molares, I.A, Truskett, T.M, Maynard, J.A, Lieberman, R.L. 登録日 2013-11-12 公開日 2014-03-12 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (3.71 Å) 主引用文献 Effects of protein engineering and rational mutagenesis on crystal lattice of single chain antibody fragments. Proteins, 82, 2014
6N7J	BDBV223 Fab bound to synthetic peptide of Bundibugyo virus Glycoprotein Stalk 分子名称: BDBV223 antibody heavy chain, BDBV223 antibody light chain, Envelope glycoprotein 著者 King, L.B, West, B.R, Saphire, E.O. 登録日 2018-11-27 公開日 2019-03-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.684 Å) 主引用文献 Cross-reactive neutralizing human survivor monoclonal antibody BDBV223 targets the ebolavirus stalk. Nat Commun, 10, 2019

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