PDB: 2917 件ウェブページステータス検索Chemie searchBIRD

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2FWO	MHC Class I H-2Kd heavy chain in complex with beta-2microglobulin and peptide derived from influenza nucleoprotein 分子名称: Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-D alpha chain, ... 著者 Mitaksov, V, Fremont, D.H. 登録日 2006-02-02 公開日 2006-02-21 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural Definition of the H-2Kd Peptide-binding Motif. J.Biol.Chem., 281, 2006
8GON	SARS-CoV-2 specific private TCR RLQ7 in complex with RLQ-T1006I-HLA-A2 分子名称: Beta-2-microglobulin, MHC class I antigen, SARS-CoV-2 specific private TCR RLQ7 alpha, ... 著者 Wu, D, Mariuzza, R.A. 登録日 2022-08-25 公開日 2023-03-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.601 Å) 主引用文献 Structural insights into protection against a SARS-CoV-2 spike variant by T cell receptor (TCR) diversity. J.Biol.Chem., 299, 2023
3RWD	rhesus macaque MHC class I molecule Mamu-B*17-IW11 分子名称: Beta-2-microglobulin, Major histocompatibility complex class I, Nef IW11 peptide from Protein Nef 著者 Wu, Y, Gao, F, Liu, J, Qi, J.X, Price, D.A, Gao, G.F. 登録日 2011-05-09 公開日 2012-03-21 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.602 Å) 主引用文献 Structural basis of diverse peptide accommodation by the rhesus macaque MHC class I molecule Mamu-B*17: insights into immune protection from simian immunodeficiency virus J.Immunol., 187, 2011
3W0W	The complex between T36-5 TCR and HLA-A24 bound to HIV-1 Nef134-10(2F) peptide in space group P212121 分子名称: 10-mer peptide from Protein Nef, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... 著者 Shimizu, A, Fukai, S, Yamagata, A, Iwamoto, A. 登録日 2012-11-05 公開日 2013-11-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.603 Å) 主引用文献 Structure of TCR and antigen complexes at an immunodominant CTL epitope in HIV-1 infection SCI REP, 3, 2013
4P2O	Crystal structure of the 2B4 TCR in complex with 2A/I-Ek 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2A peptide, 2B4 T-cell receptor alpha chain, ... 著者 Birnbaum, M.E, Ozkan, E, Garcia, K.C. 登録日 2014-03-04 公開日 2014-05-21 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.603 Å) 主引用文献 Deconstructing the Peptide-MHC Specificity of T Cell Recognition. Cell, 157, 2014
4MQ7	Structure of human CD1d-sulfatide 分子名称: (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, ... 著者 Luoma, A.M, Adams, E.J. 登録日 2013-09-15 公開日 2013-12-18 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6032 Å) 主引用文献 Crystal Structure of V delta 1 T Cell Receptor in Complex with CD1d-Sulfatide Shows MHC-like Recognition of a Self-Lipid by Human gamma delta T Cells. Immunity, 39, 2013
7P0T	CRYSTAL STRUCTURE OF THE MURINE CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX H-2DB IN COMPLEX WITH LCMV-DERIVED GP33 PEPTIDE with D-AMINOACID 分子名称: Beta-2-microglobulin, CHLORIDE ION, Derived peptide gp33-41 from LCMV, ... 著者 Broggini, L, Ricagno, S. 登録日 2021-06-30 公開日 2022-03-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.605 Å) 主引用文献 l- to d-Amino Acid Substitution in the Immunodominant LCMV-Derived Epitope gp33 Highlights the Sensitivity of the TCR Recognition Mechanism for the MHC/Peptide Structure and Dynamics. Acs Omega, 7, 2022
2GAZ	Mycobacterial lipoglycan presentation by CD1d 分子名称: (2R)-3-[(HYDROXY{[(2R,3R,5S,6R)-3,4,5-TRIHYDROXY-2,6-BIS(ALPHA-D-MANNOPYRANOSYLOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]PROPAN E-1,2-DIYL DIHEXADECANOATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, T-cell surface glycoprotein CD1d1, ... 著者 Zajonc, D.M. 登録日 2006-03-09 公開日 2006-09-26 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Structural characterization of mycobacterial phosphatidylinositol mannoside binding to mouse CD1d. J.Immunol., 177, 2006
3VXO	HLA-A24 in complex with HIV-1 Nef134-10(2F) 分子名称: 10-mer peptide from Protein Nef, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... 著者 Shimizu, A, Fukai, S, Yamagata, A, Iwamoto, A. 登録日 2012-09-20 公開日 2013-10-23 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Structure of TCR and antigen complexes at an immunodominant CTL epitope in HIV-1 infection SCI REP, 3, 2013
6VTU	DH717.1 Fab monomer in complex with man9 glycan 分子名称: DH717.1 heavy chain, DH717.1 light chain, GLYCEROL, ... 著者 Fera, D, Bronkema, N. 登録日 2020-02-13 公開日 2020-12-30 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. Cell, 184, 2021
2HFG	Crystal structure of hBR3 bound to CB3s-Fab 分子名称: CB3s Fab heavy chain, CB3s Fab light chain (kappa), Tumor necrosis factor receptor superfamily member 13C 著者 Hymowitz, S.G. 登録日 2006-06-23 公開日 2006-11-07 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Synthetic anti-BR3 antibodies that mimic BAFF binding and target both human and murine B cells. Blood, 108, 2006
6VRM	T cell receptor-p53-HLA-A2 complex 分子名称: Beta-2-microglobulin, Cellular tumor antigen p53 peptide, MHC class I antigen, ... 著者 Wu, D, Gallagher, D.T, Gowthaman, R, Pierce, B.G, Mariuzza, R.A. 登録日 2020-02-08 公開日 2020-06-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen. Nat Commun, 11, 2020
1RK0	Mhc Class I H-2Kb Heavy Chain Complexed With beta-2 Microglobulin and Herpes Simplex Virus Glycoprotein B peptide 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, Glycoprotein B, ... 著者 Miley, M.J, Messaoudi, I, Nikolich-Zugich, J, Fremont, D.H. 登録日 2003-11-20 公開日 2004-12-14 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Structural Basis for the Restoration of TCR Recognition of an MHC Allelic Variant by Peptide Secondary Anchor Substitution J.Exp.Med., 200, 2004
4GT7	An engineered disulfide bond reversibly traps the IgE-Fc3-4 in a closed, non-receptor binding conformation 分子名称: Ig epsilon chain C region, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Wurzburg, B.A, Kim, B.K, Jardetzky, T.S. 登録日 2012-08-28 公開日 2012-09-12 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 An engineered disulfide bond reversibly traps the IgE-Fc3-4 in a closed, nonreceptor binding conformation. J.Biol.Chem., 287, 2012
5IUE	Human leukocyte antigen F (HLA-F) presents peptides and regulates immunity through interactions with NK-cell receptors 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, Peptide LEU-ILE-LEU-ARG-TRP-GLU-GLN-ASP, ... 著者 Dulberger, C.L, Adams, E.J. 登録日 2016-03-17 公開日 2017-06-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Human Leukocyte Antigen F Presents Peptides and Regulates Immunity through Interactions with NK Cell Receptors. Immunity, 46, 2017
5BRZ	MAGE-A3 reactive TCR in complex with MAGE-A3 in HLA-A1 分子名称: Beta-2-microglobulin, GLU-VAL-ASP-PRO-ILE-GLY-HIS-LEU-TYR, HLA class I histocompatibility antigen, ... 著者 Raman, M.C.C, Rizkallah, P.J, Simmons, R, Donnellan, Z, Dukes, J, Bossi, G, LeProvost, G, Mahon, T, Hickman, E, LomaX, M, Oates, J, Hassan, N, Vuidepot, A, Sami, M, Cole, D.K, Jakobsen, B.K. 登録日 2015-06-01 公開日 2016-03-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Direct molecular mimicry enables off-target cardiovascular toxicity by an enhanced affinity TCR designed for cancer immunotherapy. Sci Rep, 6, 2016
4D3C	Crystal structure of the NK1 domain of HGF in complex with anti-HGF monoclonal antibody SFN68. 分子名称: HEPATOCYTE GROWTH FACTOR, SFN68 FAB 著者 Kang, Y.J, Kim, K.L, Cho, H.S, Chung, J.H. 登録日 2014-10-21 公開日 2016-01-13 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 A mechanistic basis for converting a receptor tyrosine kinase agonist to an antagonist. to be published
6GL1	HLA-E*01:03 in complex with the HIV epitope, RL9HIV 分子名称: ARG-MET-TYR-SER-PRO-THR-SER-ILE-LEU, Beta-2-microglobulin, MHC class I antigen, ... 著者 Walters, L.C, Gillespie, G.M, McMichael, A.J, Rozbesky, D, Jones, E.Y, Harlos, K. 登録日 2018-05-22 公開日 2018-08-08 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.623 Å) 主引用文献 Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding. Nat Commun, 9, 2018
7DZN	Crystal Structure of the cross-restricted T18A TCR and HLAB4201 bound to HIV-1 Gag TL9 peptide 分子名称: Beta-2-microglobulin, Gag-Pol polyprotein, MHC class I antigen, ... 著者 Liu, Y, Yin, L. 登録日 2021-01-25 公開日 2022-01-26 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 Cross-reactive TCR with alloreactivity for immunodominant HIV-1 epitope Gag TL9 with enhanced control of viral infection Biorxiv, 2021
8ZCM	Cryogenic Temperature Crystal Structure of Fc Fragment of Human IgG1 from Biosimilar VEGF-Trap 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Immunoglobulin gamma-1 heavy chain, ... 著者 Destan, E, DeMirci, H. 登録日 2024-04-30 公開日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 Cryogenic Temperature Crystal Structure of Fc Fragment of Human IgG1 from Biosimilar VEGF-Trap To Be Published
4L3C	Structure of HLA-A2 in complex with D76N b2m mutant and NY-ESO1 double mutant 分子名称: Beta-2-microglobulin, CHLORIDE ION, GLYCEROL, ... 著者 Halabelian, L, Giorgetti, S, Bellotti, V, Bolognesi, M, Ricagno, S. 登録日 2013-06-05 公開日 2013-12-25 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic beta 2-Microglobulin. J.Biol.Chem., 289, 2014
7BBG	CRYSTAL STRUCTURE OF HLA-A2-WT1-RMF AND FAB 11D06 分子名称: Beta-2-microglobulin, Heavy chain of Fab fragment 11D06, Light chain of Fab fragment 11D06, ... 著者 Bujotzek, A, Georges, G, Hanisch, L.J, Klein, C, Benz, J. 登録日 2020-12-17 公開日 2021-10-27 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 Targeting intracellular WT1 in AML with a novel RMF-peptide-MHC-specific T-cell bispecific antibody. Blood, 138, 2021
8TBV	Human Class I MHC HLA-A2 in complex with sorting nexin 24 (127-135) neoantigen KLSHQLVLL 分子名称: Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Arbuiso, A, Weiss, L.I, Brambley, C.A, Ma, J, Keller, G.L.J, Ayres, C.M, Baker, B.M. 登録日 2023-06-29 公開日 2024-01-17 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 Accurate modeling of peptide-MHC structures with AlphaFold. Structure, 32, 2024
4NQS	Knob-into-hole IgG Fc 分子名称: Ig gamma-1 chain C region, miniZ 著者 Eigenbrot, C, Ultsch, M. 登録日 2013-11-25 公開日 2014-03-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 Antiparallel Conformation of Knob and Hole Aglycosylated Half-Antibody Homodimers Is Mediated by a CH2-CH3 Hydrophobic Interaction. J.Mol.Biol., 426, 2014
7OW6	Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS G12D peptide (VVVGADGVGK) 分子名称: Beta-2-microglobulin, KRAS G12D peptide (VVVGADGVGK), MHC class I antigen, ... 著者 Karuppiah, V, Robinson, R.A. 登録日 2021-06-16 公開日 2022-07-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 Therapeutic high affinity T cell receptor targeting a KRASG12D cancer neoantigen Nat Commun, 13, 2022

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