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1DYU
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The active site base controls cofactor reactivity in Escherichia coli amine oxidase: X-ray crystallographic studies with mutational variants.
分子名称: CALCIUM ION, COPPER (II) ION, COPPER AMINE OXIDASE
著者Murray, J.M, Wilmot, C.M, Saysell, C.G, Jaeger, J, Knowles, P.F, Phillips, S.E.V, McPherson, M.J.
登録日2000-02-08
公開日2000-02-29
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献The Active Site Base Controls Cofactor Reactivity in Escherichia Coli Amine Oxidase : X-Ray Crystallographicstudies with Mutational Variants
Biochemistry, 38, 1999
5D5A
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In meso in situ serial X-ray crystallography structure of the Beta2-adrenergic receptor at 100 K
分子名称: (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol, 1,4-BUTANEDIOL, ACETAMIDE, ...
著者Huang, C.-Y, Olieric, V, Warshamanage, R, Liu, X, Kobilka, B, Kay Diederichs, K, Wang, M, Caffrey, M.
登録日2015-08-10
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.4826 Å)
主引用文献In meso in situ serial X-ray crystallography of soluble and membrane proteins at cryogenic temperatures.
Acta Crystallogr D Struct Biol, 72, 2016
1E3I
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Mouse class II alcohol dehydrogenase complex with NADH and inhibitor
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ALCOHOL DEHYDROGENASE, CLASS II, ...
著者Svensson, S, Hoog, J.O, Schneider, G, Sandalova, T.
登録日2000-06-16
公開日2000-09-12
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Crystal Structure of Mouse Class II Alcohol Dehydrogenase Reveal Determinants of Substrate Specificity and Catalytic Efficiency
J.Mol.Biol., 302, 2000
5D9Q
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Crystal Structure of the BG505 SOSIP gp140 HIV-1 Env trimer in Complex with the Broadly Neutralizing Fab PGT122 and scFv NIH45-46
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
著者Julien, J.-P, Stanfield, R.L, Ward, A.B, Wilson, I.A.
登録日2015-08-18
公開日2016-08-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (4.4 Å)
主引用文献Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design.
Plos Pathog., 12, 2016
1E3E
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BU of 1e3e by Molmil
Mouse class II alcohol dehydrogenase complex with NADH
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ALCOHOL DEHYDROGENASE, CLASS II, ...
著者Svensson, S, Hoeoeg, J.O, Schneider, G, Sandalova, T.
登録日2000-06-14
公開日2000-09-12
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Crystal Structure of Mouse Class II Alcohol Dehydrogenase Reveal Determinants of Substrate Specificity and Catalytic Efficiency
J.Mol.Biol., 302, 2000
8JZC
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Crystal structure of Geobacillus stearothermophilus NarJ
分子名称: Nitrate reductase molybdenum cofactor assembly chaperone
著者Song, W.S, Kim, J.H, Namgung, B, Cho, H.Y, Oh, H.B, Yoon, S.I.
登録日2023-07-05
公開日2024-05-15
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Complementary hydrophobic interaction of the redox enzyme maturation protein NarJ with the signal peptide of the respiratory nitrate reductase NarG.
Int.J.Biol.Macromol., 262, 2024
1E4N
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Crystal structure of the inactive mutant Monocot (Maize ZMGlu1) beta-glucosidase ZMGluE191D in complex with the natural aglycone DIMBOA
分子名称: 2,4-DIHYDROXY-7-(METHYLOXY)-2H-1,4-BENZOXAZIN-3(4H)-ONE, BETA-GLUCOSIDASE
著者Czjzek, M, Cicek, M, Bevan, D.R, Zamboni, V, Henrissat, B, Esen, A.
登録日2000-07-11
公開日2000-12-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Mechanism of Substrate (Aglycone) Specificity in Beta -Glucosidases is Revealed by Crystal Structures of Mutant Maize Beta -Glucosidase-Dimboa, -Dimboaglc, and -Dhurrin Complexes
Proc.Natl.Acad.Sci.USA, 97, 2000
6V3G
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Cryo-EM structure of Ca2+-free hsSlo1 channel
分子名称: Calcium-activated potassium channel subunit alpha-1
著者Tao, X, MacKinnon, R.
登録日2019-11-25
公開日2019-12-25
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Molecular structures of the human Slo1 K + channel in complex with beta 4.
Elife, 8, 2019
1E4L
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Crystal structure of the inactive mutant Monocot (Maize ZMGlu1) beta-glucosidase ZM Glu191Asp
分子名称: BETA-GLUCOSIDASE, CHLOROPLASTIC, GLYCEROL
著者Czjzek, M, Cicek, M, Bevan, D.R, Henrissat, B, Esen, A.
登録日2000-07-10
公開日2000-12-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Mechanism of Substrate (Aglycone) Specificity in Beta -Glucosidases is Revealed by Crystal Structures of Mutant Maize Beta -Glucosidase-Dimboa, -Dimboaglc, and -Dhurrin Complexes
Proc.Natl.Acad.Sci.USA, 97, 2000
6V4B
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DeCLIC N-terminal Domain 34-202
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Neur_chan_LBD domain-containing protein, ...
著者Delarue, M, Hu, H.D.
登録日2019-11-27
公開日2020-06-03
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural basis for allosteric transitions of a multidomain pentameric ligand-gated ion channel.
Proc.Natl.Acad.Sci.USA, 117, 2020
6MKF
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Crystal structure of penicillin binding protein 5 (PBP5) from Enterococcus faecium in the imipenem-bound form
分子名称: (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, SULFATE ION, penicillin binding protein 5 (PBP5)
著者Moon, T.M, Lee, C, D'Andrea, E.D, Peti, W, Page, R.
登録日2018-09-25
公開日2018-10-31
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The structures of penicillin-binding protein 4 (PBP4) and PBP5 fromEnterococciprovide structural insights into beta-lactam resistance.
J. Biol. Chem., 293, 2018
6MJL
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BU of 6mjl by Molmil
Crystal structure of ChREBP NLS peptide bound to importin alpha.
分子名称: ChREBP Peptide ASN-TYR-TRP-LYS-ARG-ARG-ILE-GLU-VAL, Importin subunit alpha-1
著者Jung, H, Uyeda, K.
登録日2018-09-21
公開日2019-09-25
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The structure of importin alpha and the nuclear localization peptide of ChREBP, and small compound inhibitors of ChREBP-importin alpha interactions.
Biochem.J., 477, 2020
6R5V
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BU of 6r5v by Molmil
The crystal structure of Glycoside Hydrolase BglX inactive mutant D286N from P. aeruginosa in complex with xylotriose
分子名称: DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, Periplasmic beta-glucosidase, ...
著者Batuecas, M.T, Hermoso, J.A.
登録日2019-03-25
公開日2020-04-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Catalytic Cycle of Glycoside Hydrolase BglX fromPseudomonas aeruginosaand Its Implications for Biofilm Formation.
Acs Chem.Biol., 15, 2020
6T8B
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FtsK motor domain with dsDNA, translocating state
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA translocase FtsK, MAGNESIUM ION, ...
著者Jean, N.L, Lowe, J.
登録日2019-10-24
公開日2019-11-20
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.65 Å)
主引用文献FtsK in motion reveals its mechanism for double-stranded DNA translocation.
Proc.Natl.Acad.Sci.USA, 117, 2020
6R5P
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The crystal structure of Glycoside Hydrolase BglX inactive mutant D286N from P. aeruginosa in complex with glucose
分子名称: MAGNESIUM ION, Periplasmic beta-glucosidase, beta-D-glucopyranose
著者Batuecas, M.T, Hermoso, J.A.
登録日2019-03-25
公開日2020-04-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Catalytic Cycle of Glycoside Hydrolase BglX fromPseudomonas aeruginosaand Its Implications for Biofilm Formation.
Acs Chem.Biol., 15, 2020
8JZD
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BU of 8jzd by Molmil
Crystal structure of Escherichia coli NarJ in complex with the signal peptide of E. coli NarG
分子名称: Nitrate reductase molybdenum cofactor assembly chaperone NarJ, Respiratory nitrate reductase 1 alpha chain
著者Song, W.S, Kim, J.H, Namgung, B, Cho, H.Y, Oh, H.B, Yoon, S.I.
登録日2023-07-05
公開日2024-05-15
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Complementary hydrophobic interaction of the redox enzyme maturation protein NarJ with the signal peptide of the respiratory nitrate reductase NarG.
Int.J.Biol.Macromol., 262, 2024
6MKH
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BU of 6mkh by Molmil
Crystal structure of pencillin binding protein 4 (PBP4) from Enterococcus faecalis in the imipenem-bound form
分子名称: (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, PHOSPHATE ION, pencillin binding protein 4 (PBP4)
著者D'Andrea, E.D, Moon, T.M, Peti, W, Page, R.
登録日2018-09-25
公開日2018-10-31
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献The structures of penicillin-binding protein 4 (PBP4) and PBP5 fromEnterococciprovide structural insights into beta-lactam resistance.
J. Biol. Chem., 293, 2018
8B5W
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Crystal structure of the E3 module from UBR4
分子名称: 1,2-ETHANEDIOL, ZINC ION, cDNA FLJ12511 fis, ...
著者Virdee, S, Mabbitt, P.D, Barnsby-Greer, L.
登録日2022-09-24
公開日2023-10-04
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献UBE2A and UBE2B are recruited by an atypical E3 ligase module in UBR4.
Nat.Struct.Mol.Biol., 31, 2024
6R8G
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Crystal structure of malate dehydrogenase from Plasmodium Falciparum in complex with 4-(3,4-difluorophenyl)thiazol-2-amine
分子名称: 4-[3,4-bis(fluoranyl)phenyl]-1,3-thiazol-2-amine, Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Romero, A.R, Calderone, V, Gentili, M, Lunev, S, Groves, M, Popowicz, G, Domling, A, Sattler, M.
登録日2019-04-01
公開日2020-04-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A Fragment-Based Approach Identifies an Allosteric Pocket that Impacts Malate Dehydrogenase Activity
Commun Biol, 2021
4GL7
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Structure of human placental aromatase complexed with designed inhibitor HDDG046 (compound 5)
分子名称: (6alpha,8alpha)-6-(pent-2-yn-1-yloxy)androsta-1,4-diene-3,17-dione, Cytochrome P450 19A1, PROTOPORPHYRIN IX CONTAINING FE
著者Ghosh, D.
登録日2012-08-13
公開日2012-09-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Novel aromatase inhibitors by structure-guided design.
J.Med.Chem., 55, 2012
5AKF
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THE CRYSTAL STRUCTURE OF I-DMOI Q42AK120M IN COMPLEX WITH ITS TARGET DNA NICKED IN THE CODING STRAND A AND IN THE PRESENCE OF 2MM MN
分子名称: 25MER, 5'-D(*GP*CP*CP*TP*TP*GP*CP*CP*GP*GP*GP*TP*AP*AP)-3', 5'-D(*GP*TP*TP*CP*CP*GP*GP*CP*GP*CP*GP)-3', ...
著者Molina, R, Marcaida, M.J, Redondo, P, Marenchino, M, D'Abramo, M, Montoya, G, Prieto, J.
登録日2015-03-03
公開日2015-06-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Engineering a Nickase on the Homing Endonuclease I-Dmoi Scaffold.
J.Biol.Chem., 290, 2015
6TA5
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OprM-MexA complex from the MexAB-OprM Pseudomonas aeruginosa whole assembly reconstituted in nanodiscs
分子名称: Efflux pump membrane transporter, MexA family multidrug efflux RND transporter periplasmic adaptor subunit, Outer membrane protein OprM
著者Glavier, M, Schoehn, G, Taveau, J.C, Phan, G, Daury, L, Lambert, O, Broutin, I.
登録日2019-10-29
公開日2020-09-16
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Antibiotic export by MexB multidrug efflux transporter is allosterically controlled by a MexA-OprM chaperone-like complex.
Nat Commun, 11, 2020
8K6C
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Crystal structure of SARS-CoV-2 3CLpro M49K/S301P mutant
分子名称: 3C-like proteinase nsp5
著者Zhang, L.J, Hu, Q.
登録日2023-07-25
公開日2024-06-05
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Resistance mechanisms of SARS-CoV-2 3CLpro to the non-covalent inhibitor WU-04.
Cell Discov, 10, 2024
1DSS
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BU of 1dss by Molmil
STRUCTURE OF ACTIVE-SITE CARBOXYMETHYLATED D-GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE FROM PALINURUS VERSICOLOR
分子名称: D-GLYCERALDEHYDE-3-PHOSPHATE-DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION
著者Song, S, Lin, Z.
登録日1997-06-04
公開日1998-12-09
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Structure of active site carboxymethylated D-glyceraldehyde-3-phosphate dehydrogenase from Palinurus versicolor.
J.Mol.Biol., 287, 1999
1DYS
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Endoglucanase CEL6B from Humicola insolens
分子名称: ENDOGLUCANASE
著者Davies, G.J, Brzozowski, A.M, Dauter, M, Varrot, A, Schulein, M.
登録日2000-02-08
公開日2001-02-08
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure and Function of Humicola Insolens Family 6 Cellulases: Structure of the Endoglucanase, Cel6B, at 1.6 A Resolution
Biochem.J., 348, 2000

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