PDB: 35415 件ウェブページステータス検索Chemie searchBIRD

---

5U22	Structure of N2152 from Neocallimastix frontalis 分子名称: 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, IODIDE ION, ... 著者 Jones, D.R, Abbott, D.W. 登録日 2016-11-29 公開日 2017-06-14 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.748 Å) 主引用文献 Discovery and characterization of family 39 glycoside hydrolases from rumen anaerobic fungi with polyspecific activity on rare arabinosyl substrates. J. Biol. Chem., 292, 2017
8GQU	AK-42 inhibitor binding human ClC-2 TMD 分子名称: 2-[[2,6-bis(chloranyl)-3-phenylmethoxy-phenyl]amino]pyridine-3-carboxylic acid, Chloride channel protein 2 著者 Wang, L. 登録日 2022-08-30 公開日 2023-07-05 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Cryo-EM structures of ClC-2 chloride channel reveal the blocking mechanism of its specific inhibitor AK-42. Nat Commun, 14, 2023
8AE2	Cryo-EM structure of full-length human immunoglobulin M - F(ab')2 conformation 5 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IgM C2-domain from mouse, ... 著者 Chen, Q, Rosenthal, P, Tolar, P. 登録日 2022-07-12 公開日 2022-10-26 最終更新日 2022-11-09 実験手法 ELECTRON MICROSCOPY (8.5 Å) 主引用文献 Cryomicroscopy reveals the structural basis for a flexible hinge motion in the immunoglobulin M pentamer. Nat Commun, 13, 2022
6B5I	ALDH1A2 liganded with 1-(4-cyanophenyl)-N-(3-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-1H-pyrazole-4-carboxamide (compound CM121) 分子名称: 1-(4-cyanophenyl)-N-(3-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-1H-pyrazole-4-carboxamide, Retinal dehydrogenase 2 著者 Chen, Y, Zhu, J.-Y, Schonbrunn, E. 登録日 2017-09-29 公開日 2018-01-10 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural Basis of ALDH1A2 Inhibition by Irreversible and Reversible Small Molecule Inhibitors. ACS Chem. Biol., 13, 2018
3WC8	Dimeric horse cytochrome c obtained by refolding with desalting method 分子名称: Cytochrome c, DI(HYDROXYETHYL)ETHER, HEME C, ... 著者 Parui, P.P, Deshpande, M.S, Nagao, S, Kamikubo, H, Komori, H, Higuchi, Y, Kataoka, M, Hirota, S. 登録日 2013-05-25 公開日 2013-12-11 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Formation of Oligomeric Cytochrome c during Folding by Intermolecular Hydrophobic Interaction between N- and C-Terminal alpha-Helices Biochemistry, 52, 2013
8DF0	Abp1D receptor binding domain 分子名称: Abp1D Receptor Binding Domain 著者 Tamadonfar, K.O, Pinkner, J.S, Dodson, K.W, Hultgren, S.J. 登録日 2022-06-21 公開日 2023-03-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure-function correlates of fibrinogen binding by Acinetobacter adhesins critical in catheter-associated urinary tract infections. Proc.Natl.Acad.Sci.USA, 120, 2023
4QBO	VRR_NUC domain 分子名称: MAGNESIUM ION, Nuclease 著者 Smerdon, S.J, Pennell, S, Li, J. 登録日 2014-05-08 公開日 2014-09-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 FAN1 activity on asymmetric repair intermediates is mediated by an atypical monomeric virus-type replication-repair nuclease domain. Cell Rep, 8, 2014
1K05	Crystal structure of the Focal Adhesion Targeting Domain of Focal Adhesion Kinase 分子名称: FOCAL ADHESION KINASE 1 著者 Arold, S.T, Hoellerer, M.K, Noble, M.E.M. 登録日 2001-09-18 公開日 2002-01-30 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The structural basis of localization and signaling by the focal adhesion targeting domain. Structure, 10, 2002
8DKA	Abp2D receptor binding domain R86E 分子名称: Abp2D Receptor Binding Domain R86E 著者 Tamadonfar, K.O, Pinkner, J.S, Dodson, K.W, Hultgren, S.J. 登録日 2022-07-05 公開日 2023-03-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure-function correlates of fibrinogen binding by Acinetobacter adhesins critical in catheter-associated urinary tract infections. Proc.Natl.Acad.Sci.USA, 120, 2023
8AB2	Crystal Structure of the Lactate Dehydrogenase of Cyanobacterium Aponinum in its apo form. 分子名称: 1,2-ETHANEDIOL, L-lactate dehydrogenase, TERBIUM(III) ION, ... 著者 Robin, A.Y, Girard, E, Madern, D. 登録日 2022-07-04 公開日 2022-08-03 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Deciphering Evolutionary Trajectories of Lactate Dehydrogenases Provides New Insights into Allostery. Mol.Biol.Evol., 40, 2023
8CWL	Cryo-EM structure of Human 15-PGDH in complex with small molecule SW222746 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 15-hydroxyprostaglandin dehydrogenase [NAD(+)], 2-methyl-6-[7-(piperidine-1-carbonyl)quinoxalin-2-yl]isoquinolin-1(2H)-one 著者 Huang, W, Taylor, D.J. 登録日 2022-05-19 公開日 2023-03-08 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Small molecule inhibitors of 15-PGDH exploit a physiologic induced-fit closing system. Nat Commun, 14, 2023
5TQV	Crystal structure of NADP-dependent carbonyl reductase from Burkholderia multivorans 分子名称: NADPH-dependent carbonyl reductase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2016-10-24 公開日 2016-11-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structure of NADP-dependent carbonyl reductase from Burkholderia multivorans TO BE PUBLISHED
8DEY	Ternary complex structure of Cereblon-DDB1 bound to IKZF2(ZF2,3) and the molecular glue DKY709 分子名称: (3S)-3-[5-(1-benzylpiperidin-4-yl)-1-oxo-1,3-dihydro-2H-isoindol-2-yl]piperidine-2,6-dione, DNA damage-binding protein 1, Protein cereblon, ... 著者 Ma, X, Ornelas, E, Clifton, M.C. 登録日 2022-06-21 公開日 2023-03-08 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 Discovery and characterization of a selective IKZF2 glue degrader for cancer immunotherapy. Cell Chem Biol, 30, 2023
4QET	Structure of Aldehyde Dehydrogenase from Bacillus cereus, G224D mutant 分子名称: Aldehyde dehydrogenase, SODIUM ION 著者 Ngo, H.P.T, Hong, S.H, Oh, D.K, Kang, L.W. 登録日 2014-05-19 公開日 2015-05-20 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural and Kinetic Analysis for Cofactor-binding Residues in Mammalian-like Aldehyde Dehydrogenase from Bacillus cereus Involved in Oxidation and Reduction Activity for All-trans-retinal To be Published
8D3T	Crystal structure of GalS1 from Populus trichocarpas 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Pereira, J.H, Prabhakar, P.K, Urbanowicz, B.R, Adams, P.D. 登録日 2022-06-01 公開日 2023-03-15 最終更新日 2023-04-05 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Structural and biochemical insight into a modular beta-1,4-galactan synthase in plants. Nat.Plants, 9, 2023
8B2P	CYP153A71 from Acinetobacter dieselolei bound to octanoic acid 分子名称: Cytochrome P450 alkane hydroxylase, OCTANOIC ACID (CAPRYLIC ACID), PROTOPORPHYRIN IX CONTAINING FE 著者 Opperman, D.J, Tolmie, C. 登録日 2022-09-14 公開日 2022-11-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 CYP153A71 from Alcanivorax dieselolei: Oxidation beyond Monoterminal Hydroxylation of n-Alkanes Catalysts, 2022
3WF7	Crystal structure of S6K1 kinase domain in complex with a purine derivative 1-(9H-purin-6-yl)-N-[3-(trifluoromethyl)phenyl]piperidine-4-carboxamide 分子名称: 1-(9H-purin-6-yl)-N-[3-(trifluoromethyl)phenyl]piperidine-4-carboxamide, GLYCEROL, Ribosomal protein S6 kinase beta-1, ... 著者 Niwa, H, Shirouzu, M, Yokoyama, S. 登録日 2013-07-17 公開日 2014-08-06 最終更新日 2014-10-29 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal structures of the S6K1 kinase domain in complexes with inhibitors J.Struct.Funct.Genom., 15, 2014
8D3Z	Crystal structure of GalS1 in complex with Manganese from Populus trichocarpas 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Galactan synthase, ... 著者 Pereira, J.H, Prabhakar, P.K, Urbanowicz, B.R, Adams, P.D. 登録日 2022-06-01 公開日 2023-03-15 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Structural and biochemical insight into a modular beta-1,4-galactan synthase in plants. Nat.Plants, 9, 2023
6B7V	Structure of hen egg-white lysozyme pre-treated with high-pressure homogenization at 120 MPa 分子名称: ACETATE ION, CHLORIDE ION, GLYCEROL, ... 著者 Morais, M.A.B, Nascimento, A.F.Z, Tominaga, C.Y, Cristianini, M, Tribst, A.A.L, Murakami, M.T. 登録日 2017-10-05 公開日 2018-07-25 実験手法 X-RAY DIFFRACTION (1.482 Å) 主引用文献 How high pressure pre-treatments affect the function and structure of hen egg-white lysozyme Innov Food Sci Emerg Technol, 47, 2018
1JN7	Solution Structure of a CCHH mutant of the ninth CCHC Zinc Finger of U-shaped 分子名称: U-shaped TRANSCRIPTIONAL COFACTOR, ZINC ION 著者 Kowalski, K, Mackay, J.P. 登録日 2001-07-23 公開日 2002-09-25 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Characterization of the Conserved Interaction between GATA and FOG Family Proteins J.Biol.Chem., 277, 2002
8AF6	Room temperature SSX structure of GH11 xylanase from Nectria haematococca (4000 frames) 分子名称: Endo-1,4-beta-xylanase 著者 Oberthuer, D, Andaleeb, H, Betzel, C, Perbandt, M, Yefanov, O, Zielinski, K. 登録日 2022-07-15 公開日 2022-11-16 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Rapid and efficient room-temperature serial synchrotron crystallography using the CFEL TapeDrive. Iucrj, 9, 2022
8DJD	CRYSTAL STRUCTURE OF GLYCOGEN SYNTHASE KINASE 3 BETA COMPLEXED WITH 3-[(CYCLOPROPYLMETHYL)AMINO] -N-(4-PHENYLPYRIDIN-3-YL)IMIDAZO[1,2-B]PYRIDAZINE-8-CARBOX AMIDE 分子名称: 2-[(cyclopropanecarbonyl)amino]-N-(5-phenylpyridin-3-yl)pyridine-4-carboxamide, Glycogen synthase kinase-3 beta 著者 Lewis, H.A, Muckelbauer, J.K. 登録日 2022-06-30 公開日 2023-03-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.205 Å) 主引用文献 Structure-activity relationship (SAR) studies on substituted N-(pyridin-3-yl)-2-amino-isonicotinamides as highly potent and selective glycogen synthase kinase-3 (GSK-3) inhibitors. Bioorg.Med.Chem.Lett., 81, 2023
5MBC	Structure of a bacterial light-regulated adenylyl cylcase 分子名称: Beta subunit of photoactivated adenylyl cyclase, CHLORIDE ION, FLAVIN MONONUCLEOTIDE 著者 Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. 登録日 2016-11-08 公開日 2017-04-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase. J. Mol. Biol., 429, 2017
8DJE	CRYSTAL STRUCTURE OF GLYCOGEN SYNTHASE KINASE 3 BETA COMPLEXED WITH 3-[(CYCLOPROPYLMETHYL)AMINO] -N-(4-PHENYLPYRIDIN-3-YL)IMIDAZO[1,2-B]PYRIDAZINE-8-CARBOX AMIDE 分子名称: (4S)-3-[(cyclopropylmethyl)amino]-N-(4-phenylpyridin-3-yl)imidazo[1,2-b]pyridazine-8-carboxamide, Glycogen synthase kinase-3 beta 著者 Lewis, H.A, Muckelbauer, J.K. 登録日 2022-06-30 公開日 2023-03-22 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.374 Å) 主引用文献 Design, Structure-Activity Relationships, and In Vivo Evaluation of Potent and Brain-Penetrant Imidazo[1,2- b ]pyridazines as Glycogen Synthase Kinase-3 beta (GSK-3 beta ) Inhibitors. J.Med.Chem., 66, 2023
8B27	Dihydroprecondylocarpine acetate synthase from Catharanthus roseus 分子名称: Dehydroprecondylocarpine acetate synthase, SULFATE ION 著者 Langley, C, Basquin, J, Caputi, L, O'Connor, S.E. 登録日 2022-09-13 公開日 2022-11-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Expansion of the Catalytic Repertoire of Alcohol Dehydrogenases in Plant Metabolism. Angew.Chem.Int.Ed.Engl., 61, 2022

<780781782783784785786787788789790791792793794795>