PDB: 224004 件ウェブページステータス検索Chemie searchBIRD

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7SHT	Structure of a partially disrupted IgE high affinity receptor complex bound to an omalizumab variant 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, High affinity immunoglobulin epsilon receptor subunit alpha, ... 著者 Pennington, L.F, Jardetzky, T.S. 登録日 2021-10-11 公開日 2021-12-15 実験手法 ELECTRON MICROSCOPY (7.29 Å) 主引用文献 Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex. Nat Commun, 12, 2021
3NC8	Crystal Structure of BlaC-E166A covalently bound with Mecillinam 分子名称: 2-[(1R)-1-{[(E)-azepan-1-ylmethylidene]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, Beta-lactamase, PHOSPHATE ION 著者 Tremblay, L.W, Blanchard, J.S. 登録日 2010-06-04 公開日 2011-12-14 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 BlaC-E166A covalently bound with cephalosporins and penicillins To be Published
3E62	Fragment based discovery of JAK-2 inhibitors 分子名称: 5-bromo-1H-indazol-3-amine, Tyrosine-protein kinase JAK2 著者 Antonysamy, S, Fang, W, Hirst, G, Park, F, Russell, M, Smyth, L, Sprengeler, P, Stappenbeck, F, Steensma, R, Thompson, D.A, Wilson, M, Wong, M, Zhang, A, Zhang, F. 登録日 2008-08-14 公開日 2008-10-14 最終更新日 2012-02-08 実験手法 X-RAY DIFFRACTION (1.922 Å) 主引用文献 Fragment-based discovery of JAK-2 inhibitors. Bioorg.Med.Chem.Lett., 19, 2009
3E6A	Crystal structure and Functional Analysis of Glyceraldehyde-3-phosphate Dehydrogenase from Oryza Sativa 分子名称: Glyceraldehyde-3-phosphate dehydrogenase, cytosolic, SULFATE ION 著者 Tien, Y.C, Lin, Y.H, Chang, S.L, Chen, C.J. 登録日 2008-08-15 公開日 2009-08-18 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (3.77 Å) 主引用文献 Crystal structure and Functional Analysis of Glyceraldehyde-3-phosphate Dehydrogenase from Oryza Sativa To be Published
3NHU	X-ray Crystallographic Structure Activity Relationship (SAR) of Casimiroin and its Analogs Bound to Human Quinone Reductase 2 分子名称: 6-methyl[1,3]dioxolo[4,5-h]quinolin-8(9H)-one, FLAVIN-ADENINE DINUCLEOTIDE, Ribosyldihydronicotinamide dehydrogenase [quinone], ... 著者 Sturdy, M. 登録日 2010-06-14 公開日 2012-01-11 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 X-ray Crystallographic Structure Activity Relationship (SAR) of Casimiroin and its Analogs Bound to Human Quinone Reductase 2 To be Published
3EAH	Structure of inhibited human eNOS oxygenase domain 分子名称: (3S,5E)-3-propyl-3,4-dihydrothieno[2,3-f][1,4]oxazepin-5(2H)-imine, (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, ... 著者 Garcin, E.D, Arvai, A.S, Rosenfeld, R.J, Kroeger, M.D, Crane, B.R, Andersson, G, Andrews, G, Hamley, P.J, Mallinder, P.R, Nicholls, D.J, St-Gallay, S.A, Tinker, A.C, Gensmantel, N.P, Mete, A, Cheshire, D.R, Connolly, S, Stuehr, D.J, Aberg, A, Wallace, A.V, Tainer, J.A, Getzoff, E.D. 登録日 2008-08-25 公開日 2008-10-07 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase. Nat.Chem.Biol., 4, 2008
3ETJ	Crystal structure E. coli Purk in complex with Mg, ADP, and Pi 分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, HYDROGENPHOSPHATE ION, ... 著者 Holden, H.M, Thoden, J.B. 登録日 2008-10-08 公開日 2008-10-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural analysis of the active site geometry of N(5)-Carboxyaminoimidazole ribonucleotide synthetase from Escherichia coli. Biochemistry, 47, 2008
3NO8	Crystal structure of the PHR domain from human BTBD2 Protein 分子名称: BTB/POZ domain-containing protein 2, GLYCEROL, SULFATE ION 著者 Sampathkumar, P, Miller, S, Rutter, M, Bain, K, Gheyi, T, Atwell, S, Thompson, D.A, Emtage, J.S, Wasserman, S, Sauder, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2010-06-24 公開日 2010-08-25 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of the PHR domain from human BTBD2 Protein To be Published
3NRO	Crystal Structure of putative transcriptional factor Lmo1026 from Listeria monocytogenes (FRAGMENT 52-321), Northeast Structural Genomics Consortium Target LmR194 分子名称: Lmo1026 protein 著者 Kuzin, A, Su, M, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Lee, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) 登録日 2010-06-30 公開日 2010-08-04 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Northeast Structural Genomics Consortium Target LmR194 To be Published
3NV7	Crystal structure of H.pylori phosphopantetheine adenylyltransferase mutant I4V/N76Y 分子名称: ACETIC ACID, Phosphopantetheine adenylyltransferase, SULFATE ION 著者 Chen, C.H, Cheng, C.S, Yin, H.S. 登録日 2010-07-08 公開日 2011-07-13 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal structure of H.pylori phosphopantetheine adenylyltransferase mutant I4V/N76Y To be Published
3EIT	the 2.6 angstrom crystal structure of CHBP, the Cif Homologue from Burkholderia pseudomallei 分子名称: Putative ATP/GTP binding protein 著者 Yao, Q, Zhu, Y, Shao, F. 登録日 2008-09-17 公開日 2009-02-03 最終更新日 2017-10-25 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 A bacterial type III effector family uses the papain-like hydrolytic activity to arrest the host cell cycle Proc.Natl.Acad.Sci.USA, 106, 2009
3NVZ	Crystal Structure of Bovine Xanthine Oxidase in Complex with Indole-3-Aldehyde 分子名称: 1H-INDOLE-3-CARBALDEHYDE, DIOXOTHIOMOLYBDENUM(VI) ION, FE2/S2 (INORGANIC) CLUSTER, ... 著者 Cao, H, Hille, R. 登録日 2010-07-08 公開日 2011-01-19 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Substrate orientation and specificity in xanthine oxidase: crystal structures of the enzyme in complex with indole-3-acetaldehyde and guanine. Biochemistry, 53, 2014
6YEN	Crystal structure of AmpC from E. coli with Taniborbactam (VNRX-5133) 分子名称: (10aR)-2-(((1r,4R)-4-((2-aminoethyl)amino)cyclohexyl)methyl)-6-carboxy-4-hydroxy-4,10a-dihydro-10H-benzo[5,6][1,2]oxaborinino[2,3-b][1,4,2]oxazaborol-4-uide, (3~{R})-3-[2-[4-(2-azanylethylamino)cyclohexyl]ethanoylamino]-2-oxidanyl-3,4-dihydro-1,2-benzoxaborinine-8-carboxylic acid, 1,2-ETHANEDIOL, ... 著者 Lang, P.A, Brem, J, Schofield, C.J. 登録日 2020-03-25 公開日 2020-06-24 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.418 Å) 主引用文献 Bicyclic Boronates as Potent Inhibitors of AmpC, the Class C beta-Lactamase from Escherichia coli . Biomolecules, 10, 2020
6YFI	Bacteriophage EMS014 coat protein 分子名称: coat protein 著者 Rumnieks, J, Kalnins, G, Sisovs, M, Lieknina, I, Tars, K. 登録日 2020-03-26 公開日 2020-09-02 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.248 Å) 主引用文献 Three-dimensional structure of 22 uncultured ssRNA bacteriophages: Flexibility of the coat protein fold and variations in particle shapes. Sci Adv, 6, 2020
3NZP	Crystal Structure of the Biosynthetic Arginine decarboxylase SpeA from Campylobacter jejuni, Northeast Structural Genomics Consortium Target BR53 分子名称: Arginine decarboxylase, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION 著者 Forouhar, F, Lew, S, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Belote, R.L, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) 登録日 2010-07-16 公開日 2010-09-01 最終更新日 2012-02-22 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structures of bacterial biosynthetic arginine decarboxylases. Acta Crystallogr.,Sect.F, 66, 2010
3ES2	Structure of the C-terminal phosphatase domain of P. aeruginonsa RssB 分子名称: Probable two-component response regulator 著者 Levchenko, I, Grant, R.A, Sauer, R.T, Baker, T.A. 登録日 2008-10-03 公開日 2009-10-20 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 The structure of RSSB, a clpx adaptor protein that regulates sigma s To be Published
3ESO	Human transthyretin (TTR) complexed with N-(3,5-Dibromo-4-hydroxyphenyl)-2,5-dichlorobenzamide 分子名称: 2,5-dichloro-N-(3,5-dibromo-4-hydroxyphenyl)benzamide, Transthyretin 著者 Connelly, S, Wilson, I.A. 登録日 2008-10-06 公開日 2009-04-07 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.31 Å) 主引用文献 Toward optimization of the second aryl substructure common to transthyretin amyloidogenesis inhibitors using biochemical and structural studies. J.Med.Chem., 52, 2009
3OAB	Mint deletion mutant of heterotetrameric geranyl pyrophosphate synthase in complex with ligands 分子名称: 1,2-ETHANEDIOL, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, DIMETHYLALLYL S-THIOLODIPHOSPHATE, ... 著者 Hsieh, F.-L, Chang, T.-H, Ko, T.-P, Wang, A.H.-J. 登録日 2010-08-05 公開日 2010-11-03 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Enhanced specificity of mint geranyl pyrophosphate synthase by modifying the R-loop interactions J.Mol.Biol., 404, 2010
6YHN	Crystal structure of domains 4-5 of CNFy from Yersinia pseudotuberculosis 分子名称: (R,R)-2,3-BUTANEDIOL, CHLORIDE ION, Cytotoxic necrotizing factor, ... 著者 Lukat, P, Gazdag, E.M, Heidler, T.V, Blankenfeldt, W. 登録日 2020-03-30 公開日 2020-12-30 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of bacterial cytotoxic necrotizing factor CNF Y reveals molecular building blocks for intoxication. Embo J., 40, 2021
7PK5	Phosphodiesterase PdeL (EAL domain of crystals comprising full-length protein) 分子名称: Cyclic di-GMP phosphodiesterase PdeL 著者 Fadel, J, Schirmer, T. 登録日 2021-08-25 公開日 2022-09-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (4.4 Å) 主引用文献 Phosphodiesterase PdeL (EAL domain of crystals comprising full-length protein) To Be Published
3OAZ	A non-self sugar mimic of the HIV glycan shield shows enhanced antigenicity 分子名称: CHLORIDE ION, Fab 2G12, heavy chain, ... 著者 Doores, K.J, Fulton, Z, Hong, V, Patel, M.K, Scanlan, C.N, Wormald, M.R, Finn, M.G, Burton, D.R, Wilson, I.A, Davis, B.G. 登録日 2010-08-06 公開日 2011-01-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity. Proc.Natl.Acad.Sci.USA, 107, 2010
3ENW	Substrate and inhibitor complexes of ribose 5-phosphate isomerase from Vibrio vulnificus YJ016 分子名称: RIBULOSE-5-PHOSPHATE, Ribose-5-phosphate isomerase A 著者 Min, K, Kwon, T.H, Kim, T.G. 登録日 2008-09-26 公開日 2009-09-29 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structures of substrate and inhibitor complexes of ribose 5-phosphate isomerase A from Vibrio vulnificus YJ016 Mol.Cells, 27, 2009
3O6U	Crystal Structure of CPE2226 protein from Clostridium perfringens. Northeast Structural Genomics Consortium Target CpR195 分子名称: uncharacterized protein CPE2226 著者 Vorobiev, S, Su, M, Seetharaman, J, Patel, P, Xiao, R, Ciccosanti, C, Wang, H, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) 登録日 2010-07-29 公開日 2010-08-11 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structure of CPE2226 protein from Clostridium perfringens. To be Published
6ONM	Crystal Structure of (+)-Limonene Synthase Complexed with 8,9-Difluorolinalyl Diphosphate 分子名称: (+)-limonene synthase, (3R)-8-fluoro-7-(fluoromethyl)-3-methylocta-1,6-dien-3-yl trihydrogen diphosphate, MANGANESE (II) ION 著者 Prem Kumar, R, Morehouse, B.R, Yu, Q, Oprian, D.D. 登録日 2019-04-22 公開日 2019-09-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Direct Evidence of an Enzyme-Generated LPP Intermediate in (+)-Limonene Synthase Using a Fluorinated GPP Substrate Analog. Acs Chem.Biol., 14, 2019
3NTI	Crystal structure of Tudor and Aubergine [R15(me2s)] complex 分子名称: Maternal protein tudor, peptide from Aubergine 著者 Liu, H.P, Huang, Y, Li, Z.Z, Gong, W.M, Xu, R.M. 登録日 2010-07-05 公開日 2010-09-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis for methylarginine-dependent recognition of Aubergine by Tudor Genes Dev., 24, 2010

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