3BGJ
 
 | | Crystal Structure of Human Orotidine 5'-monophosphate Decarboxylase Covalently Modified by 6-iodo-UMP | | 分子名称: | GLYCEROL, URIDINE-5'-MONOPHOSPHATE, Uridine 5'-monophosphate synthase | | 著者 | Liu, Y, Tang, H.L, Bello, A.M, Devalla, S, Kotra, L.P, Pai, E.F. | | 登録日 | 2007-11-26 | | 公開日 | 2008-11-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structure of Human Orotidine 5'-monophosphate Decarboxylase Covalently Modified by 6-iodo-UMP
To be Published
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4JS3
 | | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 057 | | 分子名称: | 2-chloro-4-methyl-N-(naphthalen-2-yl)-1,3-thiazole-5-carboxamide, ACETIC ACID, Dihydroorotate dehydrogenase (quinone), ... | | 著者 | Zhu, L, Li, H, Zhu, J, Ren, X. | | 登録日 | 2013-03-22 | | 公開日 | 2014-03-26 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 057
TO BE PUBLISHED
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3BHG
 | | Crystal structure of adenylosuccinate lyase from Legionella pneumophila | | 分子名称: | Adenylosuccinate lyase, GLYCEROL, SULFATE ION | | 著者 | Chang, C, Li, H, Freeman, L, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2007-11-28 | | 公開日 | 2007-12-04 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of adenylosuccinate lyase from Legionella pneumophila.
To be Published
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2PFM
 | | Crystal Structure of Adenylosuccinate Lyase (PurB) from Bacillus anthracis | | 分子名称: | Adenylosuccinate lyase, MALONATE ION | | 著者 | Levdikov, V.M, Blagova, E.V, Baumgart, M, Moroz, O.V, Wilkinson, A.J, Wilson, K.S. | | 登録日 | 2007-04-05 | | 公開日 | 2007-04-17 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structure of Adenylosuccinate Lyase (PurB) from Bacillus anthracis
To be Published
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2PS1
 | | S. cerevisiae orotate phosphoribosyltransferase complexed with orotic acid and PRPP | | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, MAGNESIUM ION, OROTIC ACID, ... | | 著者 | Gonzalez-Segura, L, Hurley, T.D, McClard, R.W. | | 登録日 | 2007-05-04 | | 公開日 | 2008-01-15 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Ternary complex formation and induced asymmetry in orotate phosphoribosyltransferase.
Biochemistry, 46, 2007
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5AT1
 | | STRUCTURAL CONSEQUENCES OF EFFECTOR BINDING TO THE T STATE OF ASPARTATE CARBAMOYLTRANSFERASE. CRYSTAL STRUCTURES OF THE UNLIGATED AND ATP-, AND CTP-COMPLEXED ENZYMES AT 2.6-ANGSTROMS RESOLUTION | | 分子名称: | ASPARTATE CARBAMOYLTRANSFERASE (T STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ... | | 著者 | Stevens, R.C, Gouaux, J.E, Lipscomb, W.N. | | 登録日 | 1990-04-26 | | 公開日 | 1990-10-15 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural consequences of effector binding to the T state of aspartate carbamoyltransferase: crystal structures of the unligated and ATP- and CTP-complexed enzymes at 2.6-A resolution.
Biochemistry, 29, 1990
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7K46
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2PRY
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4BJH
 | | Crystal Structure of the Aquifex Reactor Complex Formed by Dihydroorotase (H180A, H232A) with Dihydroorotate and Aspartate Transcarbamoylase with N-(phosphonacetyl)-L-aspartate (PALA) | | 分子名称: | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, 1,2-ETHANEDIOL, ASPARTATE CARBAMOYLTRANSFERASE, ... | | 著者 | Edwards, B.F.P, Martin, P.D, Grimley, E, Vaishnav, A, Fernando, R, Brunzelle, J.S, Cordes, M, Evans, H.G, Evans, D.R. | | 登録日 | 2013-04-18 | | 公開日 | 2013-12-18 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The Mononuclear Metal Center of Type-I Dihydroorotase from Aquifex Aeolicus.
Bmc Biochem., 14, 2013
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3D6N
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4LS0
 | | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH01B0033 | | 分子名称: | 2-{(E)-[2-(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]methyl}benzaldehyde, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... | | 著者 | Zhu, L, Li, H, Ren, X, Zhu, J. | | 登録日 | 2013-07-21 | | 公開日 | 2014-07-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DHO1B0033
To be Published
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4LC8
 | | Crystal structure of the mutant H128N of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP | | 分子名称: | 1,2-ETHANEDIOL, 6-HYDROXYURIDINE-5'-PHOSPHATE, CHLORIDE ION, ... | | 著者 | Fedorov, A.A, Fedorov, E.V, Desai, B, Gerlt, J.A, Almo, S.C. | | 登録日 | 2013-06-21 | | 公開日 | 2013-07-03 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.318 Å) | | 主引用文献 | Crystal structure of the mutant H128N of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP
To be Published
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4JGD
 | | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A016 | | 分子名称: | 1-[4-methyl-2-(naphthalen-2-ylamino)-1,3-thiazol-5-yl]ethanone, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... | | 著者 | Zhu, L, Zhu, J, Ren, X, Li, H. | | 登録日 | 2013-03-01 | | 公開日 | 2014-03-05 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A016
TO BE PUBLISHED
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7K2U
 | | DHODH IN COMPLEX WITH LIGAND 13 | | 分子名称: | 6-fluoro-2-(2'-fluoro[1,1'-biphenyl]-4-yl)-N-methoxy-3-methylquinoline-4-carboxamide, ACETATE ION, Dihydroorotate dehydrogenase (quinone), ... | | 著者 | Shaffer, P.L. | | 登録日 | 2020-09-09 | | 公開日 | 2020-10-21 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | A carboxylic acid isostere screen of the DHODH inhibitor Brequinar.
Bioorg.Med.Chem.Lett., 30, 2020
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2PRZ
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4JTT
 | | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 066 | | 分子名称: | 2,4-dimethyl-N-(naphthalen-2-yl)-1,3-thiazole-5-carboxamide, ACETATE ION, Dihydroorotate dehydrogenase (quinone), ... | | 著者 | Zhu, L, Li, H, Zhu, J, Ren, X. | | 登録日 | 2013-03-24 | | 公開日 | 2014-03-26 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 057
TO BE PUBLISHED
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3BK0
 | | Crystal Structure of Human Orotidine 5'-monophosphate Decarboxylase Complexed with 5-CN-UMP | | 分子名称: | 5-CYANO-URIDINE-5'-MONOPHOSPHATE, GLYCEROL, SULFATE ION, ... | | 著者 | Liu, Y, Tang, H.L, Avina, M.E.M, Kotra, L.P, Pai, E.F. | | 登録日 | 2007-12-05 | | 公開日 | 2008-11-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal Structure of Human Orotidine 5'-monophosphate Decarboxylase Complexed with 5-CN-UMP
To be Published
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4LS2
 | | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A313 | | 分子名称: | 2-[(E)-{2-[4-(3-methoxyphenyl)-1,3-thiazol-2-yl]hydrazinylidene}methyl]benzoic acid, ACETATE ION, Dihydroorotate dehydrogenase (quinone), ... | | 著者 | Zhu, L, Li, H, Ren, X, Zhu, J. | | 登録日 | 2013-07-21 | | 公開日 | 2014-07-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A313
To be Published
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2ZZ6
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4LUJ
 | | Crystal structure of Orotidine 5'-monophosphate decarboxylase from methanocaldococcus jannaschii complexed with inhibitor BMP | | 分子名称: | 6-HYDROXYURIDINE-5'-PHOSPHATE, Orotidine 5'-phosphate decarboxylase | | 著者 | Fedorov, A.A, Fedorov, E.V, Desai, B, Gerlt, J.A, Almo, S.C. | | 登録日 | 2013-07-25 | | 公開日 | 2013-08-07 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure of Orotidine 5'-monophosphate decarboxylase from methanocaldococcus jannaschii complexed with inhibitor BMP
To be Published
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3DBP
 | | Crystal Structure of Human Orotidine 5'-Monophosphate Decarboxylase Complexed with 6-NH2-UMP | | 分子名称: | 6-AMINOURIDINE 5'-MONOPHOSPHATE, Orotidine 5'-phosphate decarboxylase, SULFATE ION | | 著者 | Liu, Y, To, T, Bello, A.M, Kotra, L.P, Pai, E.F. | | 登録日 | 2008-06-02 | | 公開日 | 2009-06-23 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal Structure of Human Orotidine 5'-Monophosphate Decarboxylase Complexed with 6-NH2-UMP
To be Published
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2PRH
 | | The structures of apo- and inhibitor bound human dihydroorotate dehydrogenase reveal conformational flexibility within the inhibitor binding site | | 分子名称: | 6-CHLORO-2-(2'-FLUOROBIPHENYL-4-YL)-3-METHYLQUINOLINE-4-CARBOXYLIC ACID, DECYLAMINE-N,N-DIMETHYL-N-OXIDE, Dihydroorotate dehydrogenase, ... | | 著者 | Walse, B, Dufe, V.T, Al-Karadaghi, S. | | 登録日 | 2007-05-04 | | 公開日 | 2008-05-20 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The structures of human dihydroorotate dehydrogenase with and without inhibitor reveal conformational flexibility in the inhibitor and substrate binding sites
Biochemistry, 47, 2008
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4JTU
 | | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with brequinar analogue | | 分子名称: | 6-bromo-2-{4-[(2R)-butan-2-yl]phenyl}-3-methylquinoline-4-carboxylic acid, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... | | 著者 | Zhu, L, Zhu, J, Ren, X, Li, H. | | 登録日 | 2013-03-24 | | 公開日 | 2014-03-26 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 057
To be Published
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3AT1
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4LUI
 | | Crystal structure of Orotidine 5'-monophosphate decarboxylase from methanocaldococcus jannaschii | | 分子名称: | CHLORIDE ION, Orotidine 5'-phosphate decarboxylase | | 著者 | Fedorov, A.A, Fedorov, E.V, Desai, B, Gerlt, J.A, Almo, S.C. | | 登録日 | 2013-07-25 | | 公開日 | 2013-08-07 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure of Orotidine 5'-monophosphate decarboxylase from methanocaldococcus jannaschii
To be Published
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