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4LS0

Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH01B0033

Summary for 4LS0
Entry DOI10.2210/pdb4ls0/pdb
Related4LS1 4LS2
DescriptorDihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, OROTIC ACID, ... (6 entities in total)
Functional Keywordsoxidoreductase, fmn binding, mitochondria inner membrane, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
Biological sourceHomo sapiens (human)
Cellular locationMitochondrion inner membrane; Single-pass membrane protein: Q02127
Total number of polymer chains1
Total formula weight44516.85
Authors
Zhu, L.,Li, H.,Ren, X.,Zhu, J. (deposition date: 2013-07-21, release date: 2014-07-23, Last modification date: 2023-11-08)
Primary citationZhu, L.,Li, H.,Ren, X.,Zhu, J.
Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DHO1B0033
To be Published,
Experimental method
X-RAY DIFFRACTION (2.07 Å)
Structure validation

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