5IY4
 
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1FST
 | | CRYSTAL STRUCTURE OF TRUNCATED HUMAN RHOGDI TRIPLE MUTANT | | 分子名称: | RHO GDP-DISSOCIATION INHIBITOR 1 | | 著者 | Longenecker, K.L, Garrard, S.M, Sheffield, P.J, Derewenda, Z.S. | | 登録日 | 2000-09-11 | | 公開日 | 2001-05-02 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Protein crystallization by rational mutagenesis of surface residues: Lys to Ala mutations promote crystallization of RhoGDI.
Acta Crystallogr.,Sect.D, 57, 2001
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5J0A
 | | Crystal structure of PDZ-binding kinase | | 分子名称: | 4'-HYDROXYCINNAMIC ACID, Lymphokine-activated killer T-cell-originated protein kinase, SULFATE ION | | 著者 | Zou, Q.W, Zhou, H, Yang, X. | | 登録日 | 2016-03-28 | | 公開日 | 2016-09-07 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | | 主引用文献 | The crystal structure of an inactive dimer of PDZ-binding kinase
Biochem.Biophys.Res.Commun., 476, 2016
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5IVE
 | | Linked KDM5A Jmj Domain Bound to the Inhibitor N8 ( 5-methyl-7-oxo-6-(propan-2-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile) | | 分子名称: | 5-methyl-7-oxo-6-(propan-2-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile, Lysine-specific demethylase 5A, MANGANESE (II) ION | | 著者 | Horton, J.R, Cheng, X. | | 登録日 | 2016-03-20 | | 公開日 | 2016-07-27 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.783 Å) | | 主引用文献 | Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds.
Cell Chem Biol, 23, 2016
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1H6K
 | | nuclear Cap Binding Complex | | 分子名称: | 20 KDA NUCLEAR CAP BINDING PROTEIN, CBP80 | | 著者 | Mazza, C, Ohno, M, Segref, A, Mattaj, I.W, Cusack, S. | | 登録日 | 2001-06-18 | | 公開日 | 2001-09-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structure of the Human Nuclear CAP Binding Complex
Mol.Cell, 8, 2001
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1H69
 | | CRYSTAL STRUCTURE OF HUMAN NAD[P]H-QUINONE OXIDOREDUCTASE CO WITH 2,3,5,6,TETRAMETHYL-P-BENZOQUINONE (DUROQUINONE) AT 2.5 ANGSTROM RESOLUTION | | 分子名称: | 3-(HYDROXYMETHYL)-1-METHYL-5-(2-METHYLAZIRIDIN-1-YL)-2-PHENYL-1H-INDOLE-4,7-DIONE, FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H DEHYDROGENASE [QUINONE] 1 | | 著者 | Faig, M, Bianchet, M.A, Chen, S, Winski, S, Ross, D, Amzel, L.M. | | 登録日 | 2001-06-08 | | 公開日 | 2001-09-05 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Structure-Based Development of Anticancer Drugs: Complexes of Nad(P)H:Quinone Oxidoreductase 1 with Chemotherapeutic Quinones
Structure, 9, 2001
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1HD0
 | | HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D0 (HNRNP D0 RBD1), NMR | | 分子名称: | PROTEIN (HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D0) | | 著者 | Nagata, T, Kurihara, Y, Matsuda, G, Saeki, J, Kohno, T, Yanagida, Y, Ishikawa, F, Uesugi, S, Katahira, M. | | 登録日 | 1999-05-18 | | 公開日 | 2000-05-18 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and interactions with RNA of the N-terminal UUAG-specific RNA-binding domain of hnRNP D0.
J.Mol.Biol., 287, 1999
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1HG5
 | | CALM-N N-terminal domain of clathrin assembly lymphoid myeloid leukaemia protein, inositol(1,2,3,4,5,6)P6 complex | | 分子名称: | CLATHRIN ASSEMBLY PROTEIN SHORT FORM, INOSITOL HEXAKISPHOSPHATE | | 著者 | Ford, M.G.J, Evans, P.R, McMahon, H.T. | | 登録日 | 2000-12-12 | | 公開日 | 2001-02-12 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Simultaneous Binding of Ptdins(4,5)P2 and Clathrin by Ap180 in the Nucleation of Clathrin Lattices on Membranes
Science, 291, 2001
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1HG2
 | | CALM-N N-terminal domain of clathrin assembly lymphoid myeloid leukaemia protein, Inositol(4,5)P2 complex | | 分子名称: | CLATHRIN ASSEMBLY PROTEIN SHORT FORM, D-MYO-INOSITOL-4,5-BISPHOSPHATE | | 著者 | Ford, M.G.J, Evans, P.R, McMahon, H.T. | | 登録日 | 2000-12-12 | | 公開日 | 2001-02-12 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Simultaneous Binding of Ptdins(4,5)P2 and Clathrin by Ap180 in the Nucleation of Clathrin Lattices on Membranes
Science, 291, 2001
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1H6O
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5JLJ
 | | Crystal Structure of KPT8602 in complex with CRM1-Ran-RanBP1 | | 分子名称: | (2R)-3-{3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}-2-(pyrimidin-5-yl)propanamide, CHLORIDE ION, Exportin-1, ... | | 著者 | Fung, H.Y, Chook, Y.M. | | 登録日 | 2016-04-27 | | 公開日 | 2016-06-29 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Next-generation XPO1 inhibitor shows improved efficacy and in vivo tolerability in hematological malignancies.
Leukemia, 30, 2016
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1HAK
 | | CRYSTAL STRUCTURE OF RECOMBINANT HUMAN PLACENTAL ANNEXIN V COMPLEXED WITH K-201 AS A CALCIUM CHANNEL ACTIVITY INHIBITOR | | 分子名称: | 4-[3-{1-(4-BENZYL)PIPERODINYL}PROPIONYL]-7-METHOXY-2,3,4,5-TERTRAHYDRO-1,4-BENZOTHIAZEPINE, ANNEXIN V | | 著者 | Ago, H, Inagaki, E, Miyano, M. | | 登録日 | 1997-12-10 | | 公開日 | 1999-02-16 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of annexin V with its ligand K-201 as a calcium channel activity inhibitor.
J.Mol.Biol., 274, 1997
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1HD1
 | | HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D0 (HNRNP D0 RBD1), NMR | | 分子名称: | PROTEIN (HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D0) | | 著者 | Nagata, T, Kurihara, Y, Matsuda, G, Saeki, J, Kohno, T, Yanagida, Y, Ishikawa, F, Uesugi, S, Katahira, M. | | 登録日 | 1999-05-18 | | 公開日 | 2000-05-18 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and interactions with RNA of the N-terminal UUAG-specific RNA-binding domain of hnRNP D0.
J.Mol.Biol., 287, 1999
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1HH4
 | | Rac1-RhoGDI complex involved in NADPH oxidase activation | | 分子名称: | GERAN-8-YL GERAN, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Grizot, S, Faure, J, Fieschi, F, Vignais, P.V, Dagher, M.-C, Pebay-Peyroula, E. | | 登録日 | 2000-12-20 | | 公開日 | 2001-08-28 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal Structure of the Rac1-Rhogdi Complex Involved in Nadph Oxidase Activation
Biochemistry, 40, 2001
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1FCX
 | | ISOTYPE SELECTIVITY OF THE HUMAN RETINOIC ACID NUCLEAR RECEPTOR HRAR: THE COMPLEX WITH THE RARGAMMA-SELECTIVE RETINOID BMS184394 | | 分子名称: | 6-[HYDROXY-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTALEN-2-YL)-METHYL]-NAPHTALENE-2-CARBOXYLIC ACID, DODECYL-ALPHA-D-MALTOSIDE, RETINOIC ACID RECEPTOR GAMMA-1 | | 著者 | Klaholz, B.P, Mitschler, A, Moras, D, Structural Proteomics in Europe (SPINE) | | 登録日 | 2000-07-19 | | 公開日 | 2000-09-11 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | | 主引用文献 | Structural basis for isotype selectivity of the human retinoic acid nuclear receptor.
J.Mol.Biol., 302, 2000
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5K4L
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5JY3
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1F95
 | | SOLUTION STRUCTURE OF DYNEIN LIGHT CHAIN 8 (DLC8) AND BIM PEPTIDE COMPLEX | | 分子名称: | BCL2-LIKE 11 (APOPTOSIS FACILITATOR), DYNEIN | | 著者 | Fan, J.-S, Zhang, Q, Tochio, H, Li, M, Zhang, M. | | 登録日 | 2000-07-07 | | 公開日 | 2001-02-28 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis of diverse sequence-dependent target recognition by the 8 kDa dynein light chain.
J.Mol.Biol., 306, 2001
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1FCY
 | | ISOTYPE SELECTIVITY OF THE HUMAN RETINOIC ACID NUCLEAR RECEPTOR HRAR: THE COMPLEX WITH THE RARBETA/GAMMA-SELECTIVE RETINOID CD564 | | 分子名称: | 6-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTALENE-2-CARBONYL)-NAPHTALENE-2-CARBOXYLIC ACID, DODECYL-ALPHA-D-MALTOSIDE, RETINOIC ACID RECEPTOR GAMMA-1 | | 著者 | Klaholz, B.P, Mitschler, A, Moras, D, Structural Proteomics in Europe (SPINE) | | 登録日 | 2000-07-19 | | 公開日 | 2000-09-11 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structural basis for isotype selectivity of the human retinoic acid nuclear receptor.
J.Mol.Biol., 302, 2000
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1F96
 | | SOLUTION STRUCTURE OF DYNEIN LIGHT CHAIN 8 (DLC8) AND NNOS PEPTIDE COMPLEX | | 分子名称: | DYNEIN LIGHT CHAIN 8, PROTEIN (NNOS, NEURONAL NITRIC OXIDE SYNTHASE) | | 著者 | Fan, J.S, Zhang, Q, Tochio, H, Li, M, Zhang, M. | | 登録日 | 2000-07-07 | | 公開日 | 2001-02-28 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis of diverse sequence-dependent target recognition by the 8 kDa dynein light chain.
J.Mol.Biol., 306, 2001
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5KDH
 | | CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH A DIHYDROPYRIDOPYRIMIDINE SCAFFOLD INHIBITOR | | 分子名称: | (5~{S})-1-ethyl-5-(4-methylphenyl)-8,9-dihydro-5~{H}-furo[3,4]pyrido[3,5-~{b}]pyrimidine-2,4,6-trione, 1,2-ETHANEDIOL, Bromodomain-containing protein 4, ... | | 著者 | Zhu, J.-Y, Schonbrunn, E. | | 登録日 | 2016-06-08 | | 公開日 | 2017-08-02 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | BET Bromodomain Inhibitors with One-Step Synthesis Discovered from Virtual Screen.
J. Med. Chem., 60, 2017
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1H66
 | | CRYSTAL STRUCTURE OF HUMAN NAD[P]H-QUINONE OXIDOREDUCTASE CO WITH 2,5-diaziridinyl-3-hydroxyl-6-methyl-1,4-benzoquinone | | 分子名称: | 2,5-DIAZIRIDIN-1-YL-3-(HYDROXYMETHYL)-6-METHYLCYCLOHEXA-2,5-DIENE-1,4-DIONE, FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H DEHYDROGENASE [QUINONE] 1 | | 著者 | Faig, M, Bianchet, M.A, Winski, S, Ross, D, Amzel, L.M. | | 登録日 | 2001-06-06 | | 公開日 | 2001-09-05 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure-Based Development of Anticancer Drugs: Complexes of Nad(P)H:Quinone Oxidoreductase 1 with Chemotherapeutic Quinones
Structure, 9, 2001
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1FCZ
 | | ISOTYPE SELECTIVITY OF THE HUMAN RETINOIC ACID NUCLEAR RECEPTOR HRAR: THE COMPLEX WITH THE PANAGONIST RETINOID BMS181156 | | 分子名称: | 4-[3-OXO-3-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-PROPENYL]-BENZOIC ACID, DODECYL-ALPHA-D-MALTOSIDE, RETINOIC ACID RECEPTOR GAMMA-1 | | 著者 | Klaholz, B.P, Mitschler, A, Moras, D, Structural Proteomics in Europe (SPINE) | | 登録日 | 2000-07-19 | | 公開日 | 2000-09-11 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | | 主引用文献 | Structural basis for isotype selectivity of the human retinoic acid nuclear receptor.
J.Mol.Biol., 302, 2000
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1H89
 | | CRYSTAL STRUCTURE OF TERNARY PROTEIN-DNA COMPLEX2 | | 分子名称: | CAAT/ENHANCER BINDING PROTEIN BETA, DNA(5'-(*CP*CP*AP*GP*TP*CP*CP*GP*TP*TP*AP* AP*GP*GP*AP*TP*TP*GP*CP*GP*CP*CP*AP*CP*AP*T)-3'), DNA(5'-(*GP*AP*TP*GP*TP*GP*GP*CP*GP*CP*AP* AP*TP*CP*CP*TP*TP*AP*AP*CP*GP*GP*AP*CP*TP*G)-3'), ... | | 著者 | Tahirov, T.H, Ogata, K. | | 登録日 | 2001-01-30 | | 公開日 | 2002-01-28 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Mechanism of C-Myb-C/Ebpbeta Cooperation from Separated Sites on a Promoter
Cell(Cambridge,Mass.), 108, 2002
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1HFA
 | | CALM-N N-terminal domain of clathrin assembly lymphoid myeloid leukaemia protein, PI(4,5)P2 complex | | 分子名称: | CLATHRIN ASSEMBLY PROTEIN SHORT FORM, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | | 著者 | Ford, M.G.J, Evans, P.R, McMahon, H.T. | | 登録日 | 2000-11-30 | | 公開日 | 2001-02-12 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Simultaneous Binding of Ptdins(4,5)P2 and Clathrin by Ap180 in the Nucleation of Clathrin Lattices on Membranes
Science, 291, 2001
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