1HAK
CRYSTAL STRUCTURE OF RECOMBINANT HUMAN PLACENTAL ANNEXIN V COMPLEXED WITH K-201 AS A CALCIUM CHANNEL ACTIVITY INHIBITOR
Summary for 1HAK
Entry DOI | 10.2210/pdb1hak/pdb |
Descriptor | ANNEXIN V, 4-[3-{1-(4-BENZYL)PIPERODINYL}PROPIONYL]-7-METHOXY-2,3,4,5-TERTRAHYDRO-1,4-BENZOTHIAZEPINE (3 entities in total) |
Functional Keywords | annexin v, lipocortin v, endonexin ii, placenta anticoagulant protein-i, 35kda calelectrin, inhibitor of blood coagulation, calcium/phospholipid-binding, calcium-phospholipid-binding complex |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 72810.61 |
Authors | Ago, H.,Inagaki, E.,Miyano, M. (deposition date: 1997-12-10, release date: 1999-02-16, Last modification date: 2024-05-22) |
Primary citation | Kaneko, N.,Ago, H.,Matsuda, R.,Inagaki, E.,Miyano, M. Crystal structure of annexin V with its ligand K-201 as a calcium channel activity inhibitor. J.Mol.Biol., 274:16-20, 1997 Cited by PubMed: 9398511DOI: 10.1006/jmbi.1997.1375 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
Download full validation report