7KW7
| Atomic cryoEM structure of Hsp90-Hsp70-Hop-GR | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Glucocorticoid receptor, Heat shock 70 kDa protein 1A, ... | 著者 | Wang, R.Y, Noddings, C.M, Kirschke, E, Myasnikov, A, Johnson, J.L, Agard, D.A. | 登録日 | 2020-11-30 | 公開日 | 2021-12-08 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.57 Å) | 主引用文献 | Structure of Hsp90-Hsp70-Hop-GR reveals the Hsp90 client-loading mechanism. Nature, 601, 2022
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6ZHU
| Yeast Uba1 in complex with Ubc3 and ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ubiquitin-activating enzyme E1 1, ... | 著者 | Misra, M, Schindelin, H. | 登録日 | 2020-06-23 | 公開日 | 2022-01-12 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.18 Å) | 主引用文献 | ATP induced conformational changes facilitate E1-E2 disulfide bridging in the ubiquitin system To Be Published
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6ZVH
| EDF1-ribosome complex | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Best, K.M, Denk, T, Cheng, J, Thoms, M, Berninghausen, O, Beckmann, R. | 登録日 | 2020-07-24 | 公開日 | 2020-08-19 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | EDF1 coordinates cellular responses to ribosome collisions. Elife, 9, 2020
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5LN3
| The human 26S Proteasome at 6.8 Ang. | 分子名称: | 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ... | 著者 | Schweitzer, A, Beck, F, Sakata, E, Unverdorben, P. | 登録日 | 2016-08-03 | 公開日 | 2017-03-22 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (6.8 Å) | 主引用文献 | Molecular Details Underlying Dynamic Structures and Regulation of the Human 26S Proteasome. Mol. Cell Proteomics, 16, 2017
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5GHD
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6KL7
| Beta-arrestin 1 mutant S13D/T275D | 分子名称: | 1,2-ETHANEDIOL, BARIUM ION, Beta-arrestin-1 | 著者 | Kang, H, Choi, H.J. | 登録日 | 2019-07-29 | 公開日 | 2020-01-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.794 Å) | 主引用文献 | Conformational Dynamics and Functional Implications of Phosphorylated beta-Arrestins. Structure, 28, 2020
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4RCN
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1R6T
| crystal structure of human tryptophanyl-tRNA synthetase | 分子名称: | GLYCEROL, TRYPTOPHANYL-5'AMP, Tryptophanyl-tRNA synthetase | 著者 | Yang, X.-L, Otero, F.J, Skene, R.J, McRee, D.E, Ribas de Pouplana, L, Schimmel, P. | 登録日 | 2003-10-16 | 公開日 | 2004-01-06 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structures that suggest late development of genetic code components for differentiating aromatic side chains Proc.Natl.Acad.Sci.USA, 100, 2003
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8CVT
| Human 19S-20S proteasome, state SD2 | 分子名称: | 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ... | 著者 | Zhao, J. | 登録日 | 2022-05-18 | 公開日 | 2022-11-02 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins. Proc.Natl.Acad.Sci.USA, 119, 2022
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1R6U
| Crystal structure of an active fragment of human tryptophanyl-tRNA synthetase with cytokine activity | 分子名称: | GLYCEROL, TRYPTOPHANYL-5'AMP, Tryptophanyl-tRNA synthetase | 著者 | Yang, X.-L, Otero, F.J, Skene, R.J, McRee, D.E, Ribas de Pouplana, L, Schimmel, P. | 登録日 | 2003-10-16 | 公開日 | 2004-01-06 | 最終更新日 | 2024-10-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Functional and crystal structure analysis of active site adaptations of a potent anti-angiogenic human tRNA synthetase Structure, 15, 2007
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7BHP
| Cryo-EM structure of the human Ebp1 - 80S ribosome | 分子名称: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | 著者 | Desogus, J, Bhaskar, V, Chao, J.A. | 登録日 | 2021-01-11 | 公開日 | 2021-02-03 | 最終更新日 | 2024-11-06 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Dynamic association of human Ebp1 with the ribosome. Rna, 27, 2021
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6J4I
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1WQ3
| Escherichia coli tyrosyl-tRNA synthetase mutant complexed with 3-iodo-L-tyrosine | 分子名称: | 3-IODO-TYROSINE, Tyrosyl-tRNA synthetase | 著者 | Kobayashi, T, Sakamoto, K, Nureki, O, Takimura, T, Kamata, K, Sekine, R, Nishimura, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2004-09-20 | 公開日 | 2005-01-25 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis of nonnatural amino acid recognition by an engineered aminoacyl-tRNA synthetase for genetic code expansion Proc.Natl.Acad.Sci.USA, 102, 2005
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8T4S
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6D6I
| Ube2V1 in complex with ubiquitin variant Ubv.V1.1 and Ube2N/Ubc13 | 分子名称: | Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 1, Ubv.V1.1 | 著者 | Ceccarelli, D.F, Garg, P, Keszei, A, Sidhu, S, Sicheri, F. | 登録日 | 2018-04-21 | 公開日 | 2019-07-17 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.551 Å) | 主引用文献 | Structural and Functional Analysis of Ubiquitin-based Inhibitors That Target the Backsides of E2 Enzymes. J.Mol.Biol., 432, 2020
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6YBS
| Structure of a human 48S translational initiation complex - head | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S12, ... | 著者 | Brito Querido, J, Sokabe, M, Kraatz, S, Gordiyenko, Y, Skehel, M, Fraser, C, Ramakrishnan, V. | 登録日 | 2020-03-17 | 公開日 | 2020-09-16 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structure of a human 48Stranslational initiation complex. Science, 369, 2020
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6ZN5
| SARS-CoV-2 Nsp1 bound to a pre-40S-like ribosome complex - state 2 | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | 登録日 | 2020-07-06 | 公開日 | 2020-07-29 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020
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6ZOJ
| SARS-CoV-2-Nsp1-40S complex, composite map | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Schubert, K, Karousis, E.D, Jomaa, A, Scaiola, A, Echeverria, B, Gurzeler, L.-A, Leibundgut, M.L, Thiel, V, Muehlemann, O, Ban, N. | 登録日 | 2020-07-07 | 公開日 | 2020-07-22 | 最終更新日 | 2021-02-10 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation. Nat.Struct.Mol.Biol., 27, 2020
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6ZVJ
| Structure of a human ABCE1-bound 43S pre-initiation complex - State II | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Kratzat, H, Mackens-Kiani, T, Ameismeier, A, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | 登録日 | 2020-07-24 | 公開日 | 2020-10-07 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes. Embo J., 40, 2021
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1O0B
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1O0C
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7F5S
| human delta-METTL18 60S ribosome | 分子名称: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Takahashi, M, Kashiwagi, K, Ito, T. | 登録日 | 2021-06-22 | 公開日 | 2022-06-22 | 実験手法 | ELECTRON MICROSCOPY (2.72 Å) | 主引用文献 | METTL18-mediated histidine methylation of RPL3 modulates translation elongation for proteostasis maintenance. Elife, 11, 2022
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6ESB
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1A5R
| STRUCTURE DETERMINATION OF THE SMALL UBIQUITIN-RELATED MODIFIER SUMO-1, NMR, 10 STRUCTURES | 分子名称: | SUMO-1 | 著者 | Bayer, P, Arndt, A, Metzger, S, Mahajan, R, Melchior, F, Jaenicke, R, Becker, J. | 登録日 | 1998-02-18 | 公開日 | 1998-10-14 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure determination of the small ubiquitin-related modifier SUMO-1. J.Mol.Biol., 280, 1998
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1EVL
| CRYSTAL STRUCTURE OF A TRUNCATED FORM OF THREONYL-TRNA SYNTHETASE WITH A THREONYL ADENYLATE ANALOG | 分子名称: | 5'-O-(N-(L-THREONYL)-SULFAMOYL)ADENOSINE, THREONYL-TRNA SYNTHETASE, ZINC ION | 著者 | Sankaranarayanan, R, Dock-Bregeon, A.C, Rees, B, Moras, D. | 登録日 | 2000-04-20 | 公開日 | 2000-07-19 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Zinc ion mediated amino acid discrimination by threonyl-tRNA synthetase. Nat.Struct.Biol., 7, 2000
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